AU4761996A - Conformationally constrained reverse-turn library and methods relating thereto - Google Patents

Conformationally constrained reverse-turn library and methods relating thereto

Info

Publication number
AU4761996A
AU4761996A AU47619/96A AU4761996A AU4761996A AU 4761996 A AU4761996 A AU 4761996A AU 47619/96 A AU47619/96 A AU 47619/96A AU 4761996 A AU4761996 A AU 4761996A AU 4761996 A AU4761996 A AU 4761996A
Authority
AU
Australia
Prior art keywords
library
turn
methods relating
conformationally constrained
constrained reverse
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU47619/96A
Inventor
Michael Kahn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecumetics Ltd
Original Assignee
Molecumetics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecumetics Ltd filed Critical Molecumetics Ltd
Publication of AU4761996A publication Critical patent/AU4761996A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU47619/96A 1995-01-20 1996-01-19 Conformationally constrained reverse-turn library and methods relating thereto Abandoned AU4761996A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37590495A 1995-01-20 1995-01-20
US375904 1995-01-20
PCT/US1996/000786 WO1996022304A1 (en) 1995-01-20 1996-01-19 Conformationally constrained reverse-turn library and methods relating thereto

Publications (1)

Publication Number Publication Date
AU4761996A true AU4761996A (en) 1996-08-07

Family

ID=23482840

Family Applications (1)

Application Number Title Priority Date Filing Date
AU47619/96A Abandoned AU4761996A (en) 1995-01-20 1996-01-19 Conformationally constrained reverse-turn library and methods relating thereto

Country Status (5)

Country Link
EP (1) EP0804460A1 (en)
JP (1) JPH10512570A (en)
AU (1) AU4761996A (en)
CA (1) CA2210349A1 (en)
WO (1) WO1996022304A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184223B1 (en) * 1995-10-27 2001-02-06 Molecumetics Ltd. Reverse-turn mimetics and methods relating thereto
EP1015479A4 (en) * 1997-04-11 2002-07-24 Lilly Co Eli Combinatorial libraries of peptidomimetic macrocycles and processes therefor
AU742747B2 (en) * 1998-03-24 2002-01-10 Mimetica Pty Ltd Peptide turn mimetics
AUPP254898A0 (en) * 1998-03-24 1998-04-23 University Of Queensland, The Peptide turn mimetics
CA2284459C (en) * 1999-10-04 2012-12-11 Neokimia Inc. Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery
WO2004035587A1 (en) 2002-10-17 2004-04-29 Myriad Genetics, Inc. Reverse-turn mimetics and composition and methods relating thereto
EP1648923B1 (en) * 2003-07-31 2008-12-31 Tranzyme Pharma Inc. Spatially-defined macrocycles incorporating peptide bond surrogates
EP1648922B9 (en) * 2003-07-31 2013-04-03 Tranzyme Pharma Inc. Spatially-defined macrocyclic compounds useful for drug discovery
US8088733B2 (en) 2006-07-06 2012-01-03 Tranzyme Pharma Inc. Methods of using macrocyclic agonists of the ghrelin receptor for treatment of gastrointestinal motility disorders
JP2009040696A (en) * 2007-08-07 2009-02-26 Kikkoman Corp New angiotensin converting enzyme-inhibiting peptide
US8343958B2 (en) 2008-02-29 2013-01-01 Mimetica Pty Ltd 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5-receptor antagonists
US8377925B2 (en) 2008-02-29 2013-02-19 Mimetica Pty Ltd Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor
US8008291B2 (en) 2008-02-29 2011-08-30 Mimetica Pty Ltd 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5 receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013878A2 (en) * 1991-02-07 1992-08-20 Board Of Trustees Of The University Of Illinois Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
WO1994003494A1 (en) * 1992-08-06 1994-02-17 The Board Of Trustees Of The University Of Illinois Conformationally restricted mimetics of reverse turns and peptides containing the same
IL107166A (en) * 1992-10-01 2000-10-31 Univ Columbia Complex combinatorial chemical libraries encoded with tags
ES2204921T3 (en) * 1993-05-27 2004-05-01 Selectide Corporation SOLID PHASE LIBRARIES CODED, TOPOLOGICALLY SECREGATED.

Also Published As

Publication number Publication date
JPH10512570A (en) 1998-12-02
EP0804460A1 (en) 1997-11-05
CA2210349A1 (en) 1996-07-25
WO1996022304A1 (en) 1996-07-25

Similar Documents

Publication Publication Date Title
AU6931396A (en) Toothbrush and method for its manufacture
AU6584296A (en) Well completion system and method
AU2438595A (en) Morpholino-subunit combinatorial library and method
AU6315396A (en) Method for partioning and encoding data
AU5268696A (en) Novel compounds and methods for therapy
AU6400596A (en) Access portal and method
AU5154196A (en) Puzzle
AU6976996A (en) Computer telephony integration system and method
AU4748296A (en) Carrying case and work platform
AU8700798A (en) Intravascular apparatus and method
EP0851759A4 (en) Compounds and methods
AU1372897A (en) 2-amino-heterocycles and therapeutic uses therefor
AU6146596A (en) Lower-energy hydrogen methods and structures
AU7384796A (en) Dynamic swirl filter assemblies and methods
AU4761996A (en) Conformationally constrained reverse-turn library and methods relating thereto
AU5860996A (en) Computer game
AU5386396A (en) Mfc-quick change method and apparatus
AU6015096A (en) Antiviral method and antiviral agent
EP0737014A3 (en) Coding apparatus and methods
AU7287596A (en) Strengthening agent
AU5188296A (en) Carbopeptoids and carbonucleotoids
AU5163196A (en) Immunosuppressant
AU4794296A (en) System and method for perspective representation
AU9169398A (en) Soundproofing product and method for making same
AU692714B2 (en) Moulding methods and apparatus