AU470567B2 - Substituted indenyl acetic acids - Google Patents

Substituted indenyl acetic acids

Info

Publication number
AU470567B2
AU470567B2 AU37792/72A AU3779272A AU470567B2 AU 470567 B2 AU470567 B2 AU 470567B2 AU 37792/72 A AU37792/72 A AU 37792/72A AU 3779272 A AU3779272 A AU 3779272A AU 470567 B2 AU470567 B2 AU 470567B2
Authority
AU
Australia
Prior art keywords
acetic acids
substituted indenyl
indenyl acetic
substituted
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU37792/72A
Other languages
English (en)
Other versions
AU3779272A (en
Inventor
HOWARD JONES and MICHAEL WALTER FORDICE TSUNG-YING SHEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU3779272A publication Critical patent/AU3779272A/en
Application granted granted Critical
Publication of AU470567B2 publication Critical patent/AU470567B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU37792/72A 1971-01-21 1972-01-11 Substituted indenyl acetic acids Expired AU470567B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10862771A 1971-01-21 1971-01-21
USUS108627 1971-01-21

Publications (2)

Publication Number Publication Date
AU3779272A AU3779272A (en) 1973-07-12
AU470567B2 true AU470567B2 (en) 1976-03-18

Family

ID=22323233

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37792/72A Expired AU470567B2 (en) 1971-01-21 1972-01-11 Substituted indenyl acetic acids

Country Status (8)

Country Link
JP (1) JPS5654313B1 (xx)
AU (1) AU470567B2 (xx)
CA (1) CA983951A (xx)
CH (1) CH574405A5 (xx)
DE (1) DE2202715A1 (xx)
FR (1) FR2122589B1 (xx)
GB (1) GB1370028A (xx)
NL (1) NL7200058A (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI62287C (fi) * 1973-12-20 1982-12-10 Merck & Co Inc Foerfarande foer framstaellning av 5-fluor-2-metyl-1-(p-metylsulfinylbensyliden)-inden-3-aettiksyra
GR71725B (xx) * 1977-11-10 1983-06-22 Hoffmann La Roche
US6214876B1 (en) * 1994-07-21 2001-04-10 Eli Lilly And Company Indene-1-acetamide sPLA2 inhibitors
ES2274725B1 (es) * 2005-11-08 2008-04-01 Laboratorios Del Dr. Esteve, S.A. Indeno derivados, su preparacion y su uso como medicamentos.
US9862698B2 (en) 2014-12-16 2018-01-09 Adt Pharmaceuticals, Inc. Indenyl compounds, pharmaceutical compositions, and medical uses thereof
US20160168108A1 (en) 2014-12-16 2016-06-16 Adt Pharmaceuticals, Inc. Method of treating or preventing ras-mediated diseases
CA3096700C (en) 2018-04-26 2023-08-22 Adt Pharmaceuticals, Llc Anticancer indenes, indanes, azaindenes, azaindanes, pharmaceutical compositions and uses

Also Published As

Publication number Publication date
GB1370028A (en) 1974-10-09
JPS5654313B1 (xx) 1981-12-24
DE2202715A1 (de) 1972-07-27
CA983951A (en) 1976-02-17
NL7200058A (xx) 1972-07-25
CH574405A5 (xx) 1976-04-15
AU3779272A (en) 1973-07-12
FR2122589A1 (xx) 1972-09-01
FR2122589B1 (xx) 1975-02-07

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