AU4538489A - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
AU4538489A
AU4538489A AU45384/89A AU4538489A AU4538489A AU 4538489 A AU4538489 A AU 4538489A AU 45384/89 A AU45384/89 A AU 45384/89A AU 4538489 A AU4538489 A AU 4538489A AU 4538489 A AU4538489 A AU 4538489A
Authority
AU
Australia
Prior art keywords
polyoxyethylene glycol
component
pharmaceutical compositions
carboxylic acid
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU45384/89A
Other versions
AU625276B2 (en
Inventor
Maria Oksana Bachynsky
Martin Howard Infeld
Navnit Shah
Joel Unowsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU4538489A publication Critical patent/AU4538489A/en
Application granted granted Critical
Publication of AU625276B2 publication Critical patent/AU625276B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

Pharmaceutical product containing (a) a compound with antibacterial activity, and (b) an effective amount of an absorption-promoting 2-component system which contains as first component (b 1) an ether composed of a C6-C18-alcohol and polyoxyethylene glycol and as second component either (b 2-1) a polyoxyethylene glycol C6-C18-carboxylic acid glyceride ester, or (b 2-2) a C6-C18-carboxylic acid or a pharmaceutically utilisable salt thereof, or (b 2-3) an ester composed of two or more C6-C18-carboxylic acids, glycerol and a polyoxyethylene glycol.
AU45384/89A 1988-11-22 1989-11-21 Pharmaceutical compositions Ceased AU625276B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27459088A 1988-11-22 1988-11-22
US274590 1988-11-22

Publications (2)

Publication Number Publication Date
AU4538489A true AU4538489A (en) 1990-05-31
AU625276B2 AU625276B2 (en) 1992-07-09

Family

ID=23048828

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45384/89A Ceased AU625276B2 (en) 1988-11-22 1989-11-21 Pharmaceutical compositions

Country Status (15)

Country Link
EP (1) EP0370481B1 (en)
JP (1) JPH0774165B2 (en)
KR (1) KR900007412A (en)
AT (1) ATE94765T1 (en)
AU (1) AU625276B2 (en)
CA (1) CA2003340A1 (en)
DE (1) DE58905681D1 (en)
DK (1) DK585889A (en)
HU (1) HU205713B (en)
IE (1) IE63119B1 (en)
IL (1) IL92357A (en)
NZ (1) NZ231447A (en)
PH (1) PH26390A (en)
YU (1) YU221889A (en)
ZA (1) ZA898331B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4115849A1 (en) * 1991-05-15 1992-11-19 Lohmann Therapie Syst Lts PENETRATION PROMOTING SUBSTANCE
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
SI9400338A (en) * 1994-08-31 1996-04-30 Lek D D Vancomycin hydrochloride suspensions for peroral use and for filling into soft ,gelatine capsules.
IT1275802B1 (en) * 1994-11-03 1997-10-17 Hoffmann La Roche INTERFERONE COMPOSITION
FR2775188B1 (en) * 1998-02-23 2001-03-09 Lipha IMMEDIATE RELEASE ORAL EXTENDED RELEASE GALENIC FORM COMPRISING AN ABSORPTION PROMOTING AGENT AND USE OF THE ABSORPTION PROMOTING AGENT
IL125244A (en) * 1998-07-07 2002-12-01 Yissum Res Dev Co Pharmaceutical compositions containing low-melting waxes
US7658938B2 (en) 1999-02-22 2010-02-09 Merrion Reasearch III Limited Solid oral dosage form containing an enhancer
US8119159B2 (en) 1999-02-22 2012-02-21 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
EP1154761B1 (en) * 1999-02-22 2008-02-20 Merrion Research I Limited Solid oral dosage form containing an enhancer
EP1390383B1 (en) 2001-05-11 2012-02-29 Isis Pharmaceuticals, Inc. Antisense permeation enhancers
CA2648594C (en) 2006-04-07 2012-10-16 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
US20090280169A1 (en) 2008-05-07 2009-11-12 Merrion Research Iii Limited Compositions of peptides and processes of preparation thereof
PT2343982T (en) 2008-09-17 2017-07-04 Chiasma Inc Pharmaceutical compositions and related methods of delivery
WO2011120033A1 (en) 2010-03-26 2011-09-29 Merrion Research Iii Limited Pharmaceutical compositions of selective factor xa inhibitors for oral administration
JP2014501784A (en) 2011-01-07 2014-01-23 メリオン・リサーチ・Ｉｉｉ・リミテッド Pharmaceutical composition of iron for oral administration
CN107205948B (en) 2015-01-29 2021-12-14 诺和诺德股份有限公司 Tablets comprising a GLP-1 agonist and an enteric coating
US10238709B2 (en) 2015-02-03 2019-03-26 Chiasma, Inc. Method of treating diseases
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1168949A (en) * 1979-08-13 1984-06-12 William G. Gorman Cleansing compositions
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
EP0126348A2 (en) * 1983-05-19 1984-11-28 Kyoto Pharmaceutical Industries, Ltd. Composition for rectal administration and method of promoting rectal drug absorption
JPS59212427A (en) * 1983-05-19 1984-12-01 Kyoto Yakuhin Kogyo Kk Composition for rectum administration
CA1256799A (en) * 1984-02-22 1989-07-04 Walter Fuller Suppositories
EP0179583A1 (en) * 1984-10-04 1986-04-30 Merck & Co. Inc. A system for enhancing the water dissolution rate and solubility of poorly soluble drugs

Also Published As

Publication number Publication date
ZA898331B (en) 1990-07-25
KR900007412A (en) 1990-06-01
PH26390A (en) 1992-07-02
AU625276B2 (en) 1992-07-09
EP0370481B1 (en) 1993-09-22
DE58905681D1 (en) 1993-10-28
IE893718L (en) 1990-05-22
YU221889A (en) 1992-05-28
NZ231447A (en) 1992-09-25
JPH0774165B2 (en) 1995-08-09
EP0370481A2 (en) 1990-05-30
ATE94765T1 (en) 1993-10-15
CA2003340A1 (en) 1990-05-22
IE63119B1 (en) 1995-03-22
IL92357A0 (en) 1990-07-26
IL92357A (en) 1994-10-07
JPH02180837A (en) 1990-07-13
HUT52374A (en) 1990-07-28
DK585889D0 (en) 1989-11-21
DK585889A (en) 1990-05-23
HU896123D0 (en) 1990-02-28
HU205713B (en) 1992-06-29
EP0370481A3 (en) 1991-01-16

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