AU4499499A - A polypeptide structure for use as a scaffold - Google Patents

A polypeptide structure for use as a scaffold

Info

Publication number
AU4499499A
AU4499499A AU44994/99A AU4499499A AU4499499A AU 4499499 A AU4499499 A AU 4499499A AU 44994/99 A AU44994/99 A AU 44994/99A AU 4499499 A AU4499499 A AU 4499499A AU 4499499 A AU4499499 A AU 4499499A
Authority
AU
Australia
Prior art keywords
scaffold
polypeptide structure
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU44994/99A
Inventor
Johan Desmet
Hendricus Hoogenboom
Simon Hufton
Erwin Sablon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Innogenetics NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA
Publication of AU4499499A publication Critical patent/AU4499499A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
AU44994/99A 1999-04-01 1999-04-01 A polypeptide structure for use as a scaffold Abandoned AU4499499A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1999/002283 WO2000060070A1 (en) 1999-04-01 1999-04-01 A polypeptide structure for use as a scaffold

Publications (1)

Publication Number Publication Date
AU4499499A true AU4499499A (en) 2000-10-23

Family

ID=8167259

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44994/99A Abandoned AU4499499A (en) 1999-04-01 1999-04-01 A polypeptide structure for use as a scaffold

Country Status (4)

Country Link
EP (1) EP1163339A1 (en)
AU (1) AU4499499A (en)
CA (1) CA2367212A1 (en)
WO (1) WO2000060070A1 (en)

Families Citing this family (39)

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EP1318195A1 (en) * 2001-12-10 2003-06-11 CatchMabs B.V. A structure for presenting desired peptide sequences
US9321832B2 (en) 2002-06-28 2016-04-26 Domantis Limited Ligand
DE60335000D1 (en) 2002-09-06 2010-12-30 Isogenica Ltd IN VITRO PEPTIDE EXPRESSION BANK
WO2004101620A2 (en) * 2003-05-01 2004-11-25 Compound Therapeutics, Inc. Serum albumin scaffold-based proteins and uses thereof
US20060008844A1 (en) 2004-06-17 2006-01-12 Avidia Research Institute c-Met kinase binding proteins
US7749694B2 (en) 2004-12-31 2010-07-06 The Regents Of The University Of California C-type lectin fold as a scaffold for massive sequence variation
WO2007134303A2 (en) 2006-05-15 2007-11-22 Avidbiotics Corporation Modified bacteriocins and methods for their use
US7700729B2 (en) 2006-05-15 2010-04-20 Avidbiotics Corporation Modified bacteriocins and methods for their use
US8445639B2 (en) 2006-05-15 2013-05-21 Avidbiotics Corporation Recombinant bacteriophage and methods for their use
CN101641115B (en) 2007-03-08 2013-04-24 卡罗拜奥斯制药公司 Epha3 antibodies for the treatment of solid tumors
AU2009307249B2 (en) 2008-10-20 2012-11-01 Gwangju Institute Of Science And Technology Bipodal peptide binder
CN102405237A (en) 2009-03-06 2012-04-04 卡罗拜奥斯制药公司 Treatment of leukemias and chronic myeloproliferative diseases with antibodies to epha3
AU2010326024A1 (en) 2009-12-02 2012-07-05 Amgen Inc. Binding proteins that bind to human FGFR1c, human beta-Klotho and both human FGFR1c and human beta-Klotho
CN109310766A (en) * 2016-02-26 2019-02-05 伊蒙纽斯私人有限公司 Multispecific molecule
AU2017238172A1 (en) 2016-03-21 2018-09-13 Marengo Therapeutics, Inc. Multispecific and multifunctional molecules and uses thereof
CN117327650A (en) 2016-04-13 2024-01-02 维维雅生物技术公司 Ex vivo BITE activated T cells
WO2017210598A1 (en) 2016-06-03 2017-12-07 Amgen Inc. Compositions and methods for treating an articular disorder
WO2018057955A1 (en) 2016-09-23 2018-03-29 Elstar Therapeutics, Inc. Multispecific antibody molecules comprising lambda and kappa light chains
WO2018151820A1 (en) 2017-02-16 2018-08-23 Elstar Therapeutics, Inc. Multifunctional molecules comprising a trimeric ligand and uses thereof
WO2018195283A1 (en) 2017-04-19 2018-10-25 Elstar Therapeutics, Inc. Multispecific molecules and uses thereof
WO2018201047A1 (en) 2017-04-28 2018-11-01 Elstar Therapeutics, Inc. Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
EP3630836A1 (en) 2017-05-31 2020-04-08 Elstar Therapeutics, Inc. Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
WO2019035938A1 (en) 2017-08-16 2019-02-21 Elstar Therapeutics, Inc. Multispecific molecules that bind to bcma and uses thereof
EP3720881A1 (en) 2017-12-08 2020-10-14 Elstar Therapeutics, Inc. Multispecific molecules and uses thereof
US20210238280A1 (en) 2018-03-14 2021-08-05 Elstar Therapeutics, Inc. Multifunctional molecules that bind to calreticulin and uses thereof
EP3765516A2 (en) 2018-03-14 2021-01-20 Elstar Therapeutics, Inc. Multifunctional molecules and uses thereof
DE202019005887U1 (en) 2018-07-03 2023-06-14 Marengo Therapeutics, Inc. Anti-TCR antibody molecules and uses thereof
US20220242957A1 (en) 2018-09-27 2022-08-04 Marengo Therapeutics, Inc. Csf1r/ccr2 multispecific antibodies
CA3130628A1 (en) 2019-02-21 2020-08-27 Marengo Therapeutics, Inc. Multifunctional molecules that bind to t cells and uses thereof to treat autoimmune disorders
CN114126714A (en) 2019-02-21 2022-03-01 马伦戈治疗公司 anti-TCR antibody molecules and uses thereof
CN114026122A (en) 2019-02-21 2022-02-08 马伦戈治疗公司 Multifunctional molecules that bind to T cell-associated cancer cells and uses thereof
JP2022521937A (en) 2019-02-21 2022-04-13 マレンゴ・セラピューティクス，インコーポレーテッド Antibody molecules that bind to NKp30 and their use
JP2022521750A (en) 2019-02-21 2022-04-12 マレンゴ・セラピューティクス，インコーポレーテッド Multifunctional molecule that binds to calreticulin and its use
EP4084821A4 (en) 2020-01-03 2024-04-24 Marengo Therapeutics Inc Multifunctional molecules that bind to cd33 and uses thereof
EP4139363A1 (en) 2020-04-24 2023-03-01 Marengo Therapeutics, Inc. Multifunctional molecules that bind to t cell related cancer cells and uses thereof
EP4204458A1 (en) 2020-08-26 2023-07-05 Marengo Therapeutics, Inc. Methods of detecting trbc1 or trbc2
KR20230074144A (en) 2020-08-26 2023-05-26 마렝고 테라퓨틱스, 인크. Antibody molecules that bind to NKp30 and uses thereof
AU2021331075A1 (en) 2020-08-26 2023-04-06 Marengo Therapeutics, Inc. Multifunctional molecules that bind to calreticulin and uses thereof
WO2022216993A2 (en) 2021-04-08 2022-10-13 Marengo Therapeutics, Inc. Multifuntional molecules binding to tcr and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773253A (en) * 1993-01-22 1998-06-30 Bristol-Myers Squibb Company MYPPPY variants of CTL A4 and uses thereof
AUPP221098A0 (en) * 1998-03-06 1998-04-02 Diatech Pty Ltd V-like domain binding molecules
EP0947582A1 (en) * 1998-03-31 1999-10-06 Innogenetics N.V. A polypeptide structure for use as a scaffold

Also Published As

Publication number Publication date
EP1163339A1 (en) 2001-12-19
WO2000060070A1 (en) 2000-10-12
CA2367212A1 (en) 2000-10-12

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase