AU4342000A - Soluble recombinant endostatin and method of making same from (streptomyces sp) - Google Patents

Soluble recombinant endostatin and method of making same from (streptomyces sp)

Info

Publication number
AU4342000A
AU4342000A AU43420/00A AU4342000A AU4342000A AU 4342000 A AU4342000 A AU 4342000A AU 43420/00 A AU43420/00 A AU 43420/00A AU 4342000 A AU4342000 A AU 4342000A AU 4342000 A AU4342000 A AU 4342000A
Authority
AU
Australia
Prior art keywords
streptomyces
making same
soluble recombinant
recombinant endostatin
endostatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU43420/00A
Inventor
Charles L. Desanti
William R. Strohl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU4342000A publication Critical patent/AU4342000A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
AU43420/00A 1999-04-13 2000-04-12 Soluble recombinant endostatin and method of making same from (streptomyces sp) Abandoned AU4342000A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12908499P 1999-04-13 1999-04-13
US60129084 1999-04-13
PCT/US2000/009747 WO2000060945A1 (en) 1999-04-13 2000-04-12 SOLUBLE RECOMBINANT ENDOSTATIN AND METHOD OF MAKING SAME FROM $i(STREPTOMYCES SP)

Publications (1)

Publication Number Publication Date
AU4342000A true AU4342000A (en) 2000-11-14

Family

ID=22438387

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43420/00A Abandoned AU4342000A (en) 1999-04-13 2000-04-12 Soluble recombinant endostatin and method of making same from (streptomyces sp)

Country Status (2)

Country Link
AU (1) AU4342000A (en)
WO (1) WO2000060945A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001060839A2 (en) * 2000-02-18 2001-08-23 The United States Of America, As Represented By Secretary Of The Department Of Health And Human Services Method for refolding recombinant endostatin
EP1668129B1 (en) * 2003-08-29 2008-10-29 Children's Medical Center Corporation Anti-angiogenic peptides from the n-terminus of endostatin
US7524811B2 (en) 2003-08-29 2009-04-28 Children's Medical Center Corporation Anti-angiogenic peptides from the N-terminus of endostatin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5854205A (en) * 1995-10-23 1998-12-29 The Children's Medical Center Corporation Therapeutic antiangiogenic compositions and methods
NZ321356A (en) * 1995-10-23 1998-11-25 Childrens Medical Center Endostatin and its use in antiangiogenic compositions

Also Published As

Publication number Publication date
WO2000060945A1 (en) 2000-10-19

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase