AU4319189A - Production of interleukin-2 polypeptides in pichia pastoris yeast cells - Google Patents

Production of interleukin-2 polypeptides in pichia pastoris yeast cells

Info

Publication number
AU4319189A
AU4319189A AU43191/89A AU4319189A AU4319189A AU 4319189 A AU4319189 A AU 4319189A AU 43191/89 A AU43191/89 A AU 43191/89A AU 4319189 A AU4319189 A AU 4319189A AU 4319189 A AU4319189 A AU 4319189A
Authority
AU
Australia
Prior art keywords
interleukin
polypeptides
production
yeast cells
pichia pastoris
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU43191/89A
Inventor
Geneva Ruth Davis
Gonul Velicelebi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIBIA Neurosciences Inc
Original Assignee
Salk Institute Biotechnology Industrial Associates Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Institute Biotechnology Industrial Associates Inc filed Critical Salk Institute Biotechnology Industrial Associates Inc
Publication of AU4319189A publication Critical patent/AU4319189A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU43191/89A 1988-09-09 1989-09-07 Production of interleukin-2 polypeptides in pichia pastoris yeast cells Abandoned AU4319189A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24296488A 1988-09-09 1988-09-09
US242964 1994-05-16

Publications (1)

Publication Number Publication Date
AU4319189A true AU4319189A (en) 1990-04-02

Family

ID=22916817

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43191/89A Abandoned AU4319189A (en) 1988-09-09 1989-09-07 Production of interleukin-2 polypeptides in pichia pastoris yeast cells

Country Status (4)

Country Link
AU (1) AU4319189A (en)
IE (1) IE892880L (en)
IL (1) IL91512A0 (en)
WO (1) WO1990002810A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
WO1992013951A1 (en) * 1991-02-04 1992-08-20 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of human serum albumin in methylotrophic yeast cells
WO1992017595A1 (en) * 1991-04-01 1992-10-15 The Salk Institute Biotechnology/Industrial Associates, Inc. Genes which influence pichia proteolytic activity, and uses therefor
KR20030044695A (en) * 2001-11-30 2003-06-09 정종문 Manufacturing method of recombinant protein human interleukin-2 in pichia pastoris and pichia pastoris expressing recombinant protein human interleukin-2
CN100383249C (en) * 2005-04-28 2008-04-23 中国人民解放军第三军医大学 Expression of interleukin 24 from yeast cell
CN106191181B (en) 2016-07-22 2019-12-13 江苏江山聚源生物技术有限公司 Fermentation process for expressing recombinant protein by pichia pastoris
WO2024173576A1 (en) * 2023-02-14 2024-08-22 Amcyte Pharma, Inc. Interleukin formulations for ex vivo use
WO2024173571A1 (en) * 2023-02-14 2024-08-22 Amcyte Pharma, Inc. Interleukin formulations for in vivo use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511502A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins

Also Published As

Publication number Publication date
WO1990002810A1 (en) 1990-03-22
IE892880L (en) 1990-03-09
IL91512A0 (en) 1990-04-29

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