AU4310600A - Spectral bio-imaging of the eye - Google Patents

Spectral bio-imaging of the eye

Info

Publication number
AU4310600A
AU4310600A AU43106/00A AU4310600A AU4310600A AU 4310600 A AU4310600 A AU 4310600A AU 43106/00 A AU43106/00 A AU 43106/00A AU 4310600 A AU4310600 A AU 4310600A AU 4310600 A AU4310600 A AU 4310600A
Authority
AU
Australia
Prior art keywords
eye
imaging
spectral bio
bio
spectral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU43106/00A
Inventor
Michael Adel
Robert A. Buckwald
Dario Cabib
Tamir Gil
Eli Horn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Spectral Imaging Ltd
Original Assignee
Applied Spectral Imaging Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12984299A external-priority patent/IL129842A/en
Priority claimed from US09/307,569 external-priority patent/US6276798B1/en
Application filed by Applied Spectral Imaging Ltd filed Critical Applied Spectral Imaging Ltd
Publication of AU4310600A publication Critical patent/AU4310600A/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/50—Image enhancement or restoration using two or more images, e.g. averaging or subtraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/2823—Imaging spectrometer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
    • G01J3/50—Measurement of colour; Colour measuring devices, e.g. colorimeters using electric radiation detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
    • G01J3/50—Measurement of colour; Colour measuring devices, e.g. colorimeters using electric radiation detectors
    • G01J3/502—Measurement of colour; Colour measuring devices, e.g. colorimeters using electric radiation detectors using a dispersive element, e.g. grating, prism
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/00—2D [Two Dimensional] image generation
    • G06T11/001—Texturing; Colouring; Generation of texture or colour
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/90—Determination of colour characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14555—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for the eye fundus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/7257—Details of waveform analysis characterised by using transforms using Fourier transforms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
    • G01J2003/467—Colour computing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
    • G01J3/462—Computing operations in or between colour spaces; Colour management systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
    • G01J3/50—Measurement of colour; Colour measuring devices, e.g. colorimeters using electric radiation detectors
    • G01J3/51—Measurement of colour; Colour measuring devices, e.g. colorimeters using electric radiation detectors using colour filters
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10141—Special mode during image acquisition
    • G06T2207/10152—Varying illumination
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30041—Eye; Retina; Ophthalmic

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Theoretical Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Optics & Photonics (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Eye Examination Apparatus (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AU43106/00A 1999-05-07 2000-05-03 Spectral bio-imaging of the eye Abandoned AU4310600A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IL12984299A IL129842A (en) 1999-05-07 1999-05-07 Method and apparatus for spectral bio-imaging of the eye
IL129842 1999-05-07
US09/307,569 US6276798B1 (en) 1998-09-29 1999-05-10 Spectral bio-imaging of the eye
US09307569 1999-05-10
PCT/IL2000/000255 WO2000067635A1 (en) 1999-05-07 2000-05-03 Spectral bio-imaging of the eye

Publications (1)

Publication Number Publication Date
AU4310600A true AU4310600A (en) 2000-11-21

Family

ID=26323836

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43106/00A Abandoned AU4310600A (en) 1999-05-07 2000-05-03 Spectral bio-imaging of the eye

Country Status (4)

Country Link
EP (1) EP1182960A1 (en)
JP (1) JP2002543863A (en)
AU (1) AU4310600A (en)
WO (1) WO2000067635A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7711403B2 (en) * 2001-04-05 2010-05-04 Rhode Island Hospital Non-invasive determination of blood components
GB2375679A (en) * 2001-04-09 2002-11-20 Patrick Kerr Retinal function camera using plural light wavelengths to produce a retinal function image showing haemoglobin oxygenation.
EP1461769A1 (en) * 2001-12-31 2004-09-29 Gyros AB Method and arrangement for reducing noise in a microfluid device
US7221783B2 (en) 2001-12-31 2007-05-22 Gyros Patent Ab Method and arrangement for reducing noise
JP4080812B2 (en) * 2002-08-09 2008-04-23 浜松ホトニクス株式会社 System that can measure chromaticity in visible and invisible regions
DE10362401B3 (en) 2002-08-28 2022-03-10 Carl Zeiss Meditec Ag Microscopy system and microscopy method
US20040202356A1 (en) * 2003-04-10 2004-10-14 Stookey George K. Optical detection of dental caries
WO2005084526A1 (en) * 2004-02-20 2005-09-15 Riken Retina function optical measuring method and instrument
US7500751B2 (en) * 2004-03-12 2009-03-10 Yokohama Tlo Company Ltd. Ocular fundus portion analyzer and ocular fundus portion analyzing method
JP4505852B2 (en) * 2004-04-13 2010-07-21 学校法人早稲田大学 Fundus spectral imaging device
US7270543B2 (en) 2004-06-29 2007-09-18 Therametric Technologies, Inc. Handpiece for caries detection
KR20070083854A (en) * 2004-09-29 2007-08-24 머티리얼스 리서치 서비시즈 Ir spectrographic apparatus and method for diagnosis of disease
JP4656924B2 (en) * 2004-12-03 2011-03-23 株式会社トプコン Spectral fundus image data measurement device
JP4756854B2 (en) * 2004-12-03 2011-08-24 株式会社トプコン Spectral fundus image data measuring apparatus and measuring method
JP4594208B2 (en) * 2005-10-25 2010-12-08 株式会社スペクトラテック Functional confocal image display device
GB0608258D0 (en) * 2006-04-26 2006-06-07 Perkinelmer Singapore Pte Ltd Spectroscopy using attenuated total internal reflectance (ATR)
JP5094066B2 (en) * 2006-07-20 2012-12-12 富士フイルム株式会社 Method and apparatus for operating image processing apparatus, and electronic endoscope system
US8360771B2 (en) 2006-12-28 2013-01-29 Therametric Technologies, Inc. Handpiece for detection of dental demineralization
EP2370951B1 (en) 2008-11-27 2016-10-05 Koninklijke Philips N.V. Generation of a multicolour image of an unstained biological specimen
JP5618533B2 (en) * 2008-12-26 2014-11-05 キヤノン株式会社 Optical coherence tomographic information acquisition apparatus, imaging apparatus, and imaging method
JP5478103B2 (en) * 2009-04-15 2014-04-23 興和株式会社 Image processing method
JP2011002341A (en) * 2009-06-18 2011-01-06 Olympus Corp Microscopic system, specimen observation method, and program
JP5576993B2 (en) 2012-05-30 2014-08-20 パナソニック株式会社 Image measuring apparatus, image measuring method, and image measuring system
EP3275361B1 (en) * 2016-07-29 2024-06-05 Leica Instruments (Singapore) Pte. Ltd. Medical imaging apparatus and method for the imaging of a light-sensitive object, such as biological tissue
EP3826528A4 (en) 2018-07-25 2022-07-27 Natus Medical Incorporated Real-time removal of ir led reflections from an image
US20200288965A1 (en) * 2019-03-11 2020-09-17 Spring Biomed Vision Ltd. System and method for enhanced imaging of biological tissue
JP2021048958A (en) * 2019-09-24 2021-04-01 株式会社ニコン Imaging method, ophthalmologic apparatus, and program
TWI714378B (en) 2019-12-04 2020-12-21 國立臺灣大學 A large-angle optical raster scanning system for high speed deep tissue imaging
CN114343625B (en) * 2021-12-17 2024-04-26 杭州电子科技大学 Non-contact capillary blood gas parameter determination method based on color image analysis and application

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5784162A (en) * 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
EP0767361B1 (en) * 1993-07-22 2000-02-23 Applied Spectral Imaging Ltd. Method and apparatus for spectral imaging

Also Published As

Publication number Publication date
WO2000067635A1 (en) 2000-11-16
JP2002543863A (en) 2002-12-24
EP1182960A1 (en) 2002-03-06

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase