AU3769997A - 2,3-dihydro-1,4-benzothiazepines, their preparation and their use as intermediates - Google Patents

2,3-dihydro-1,4-benzothiazepines, their preparation and their use as intermediates

Info

Publication number
AU3769997A
AU3769997A AU37699/97A AU3769997A AU3769997A AU 3769997 A AU3769997 A AU 3769997A AU 37699/97 A AU37699/97 A AU 37699/97A AU 3769997 A AU3769997 A AU 3769997A AU 3769997 A AU3769997 A AU 3769997A
Authority
AU
Australia
Prior art keywords
benzothiazepines
dihydro
intermediates
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU37699/97A
Inventor
Nicholas John Holman
Gerald Bernard Tometzki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll GmbH filed Critical Knoll GmbH
Publication of AU3769997A publication Critical patent/AU3769997A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
AU37699/97A 1996-08-02 1997-07-22 2,3-dihydro-1,4-benzothiazepines, their preparation and their use as intermediates Abandoned AU3769997A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9616279.7A GB9616279D0 (en) 1996-08-02 1996-08-02 Chemical process
GB9616279 1996-08-02
PCT/EP1997/003945 WO1998005657A1 (en) 1996-08-02 1997-07-22 2,3-dihydro-1,4-benzothiazepines, their preparation and their use as intermediates

Publications (1)

Publication Number Publication Date
AU3769997A true AU3769997A (en) 1998-02-25

Family

ID=10797933

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37699/97A Abandoned AU3769997A (en) 1996-08-02 1997-07-22 2,3-dihydro-1,4-benzothiazepines, their preparation and their use as intermediates

Country Status (3)

Country Link
AU (1) AU3769997A (en)
GB (1) GB9616279D0 (en)
WO (1) WO1998005657A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7015212B1 (en) 1999-05-12 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Thiazepine inhibitors of HIV-1 integrase
US7544678B2 (en) * 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
WO2008021432A2 (en) * 2006-08-17 2008-02-21 The Trustees Of Columbia University In The City Of New York Compositions and methods for treatment of conditions affecting the nervous system
ME01989B (en) 2008-03-03 2012-08-31 Servier Lab Process for preparing benzothiazepines from gamma-aminoalkylbenzenes
CN111620838A (en) * 2020-05-16 2020-09-04 西安都创医药科技有限公司 Preparation method of chloro-benzothiepin compound, product prepared by preparation method and application of chloro-benzothiepin compound
CN111548325A (en) * 2020-05-16 2020-08-18 西安都创医药科技有限公司 Preparation method of halogenated benzothiazepine compound, product prepared by preparation method and application of product
CN111518055A (en) * 2020-05-16 2020-08-11 西安都创医药科技有限公司 Preparation method of benzothiazepine oxide, product prepared by preparation method and application of product
CN111574475B (en) * 2020-06-03 2022-09-20 西安都创医药科技有限公司 Preparation method of halogenated benzothiepin oxide, product prepared by preparation method and application of product

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9203347D0 (en) * 1992-02-17 1992-04-01 Wellcome Found Hypolipidaemic compounds
CA2148584A1 (en) * 1992-11-09 1994-05-26 John Rosindale Housley Therapeutic agents

Also Published As

Publication number Publication date
GB9616279D0 (en) 1996-09-11
WO1998005657A1 (en) 1998-02-12

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