AU3340797A - Modified oligonucleotides - Google Patents

Modified oligonucleotides

Info

Publication number
AU3340797A
AU3340797A AU33407/97A AU3340797A AU3340797A AU 3340797 A AU3340797 A AU 3340797A AU 33407/97 A AU33407/97 A AU 33407/97A AU 3340797 A AU3340797 A AU 3340797A AU 3340797 A AU3340797 A AU 3340797A
Authority
AU
Australia
Prior art keywords
modified oligonucleotides
oligonucleotides
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU33407/97A
Inventor
Alain De Mesmaeker
Jacques Lebreton
Sebastian Wendeborn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG, Novartis AG filed Critical Ciba Geigy AG
Publication of AU3340797A publication Critical patent/AU3340797A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
AU33407/97A 1996-06-28 1997-06-19 Modified oligonucleotides Abandoned AU3340797A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96810431 1996-06-28
EP96810431 1996-06-28
PCT/EP1997/003192 WO1998000434A1 (en) 1996-06-28 1997-06-19 Modified oligonucleotides

Publications (1)

Publication Number Publication Date
AU3340797A true AU3340797A (en) 1998-01-21

Family

ID=8225638

Family Applications (1)

Application Number Title Priority Date Filing Date
AU33407/97A Abandoned AU3340797A (en) 1996-06-28 1997-06-19 Modified oligonucleotides

Country Status (3)

Country Link
AU (1) AU3340797A (en)
WO (1) WO1998000434A1 (en)
ZA (1) ZA975742B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10238722A1 (en) 2002-08-23 2004-03-11 Bayer Ag Improving attention, concentration, cognition, learning and/or memory performance, using selective phosphodiesterase 9A inhibitors, preferably 4H-pyrazolo-(3,4-d)-pyrimidin-4-one derivatives
US8648085B2 (en) 2007-11-30 2014-02-11 Boehringer Ingelheim International Gmbh 1, 5-dihydro-pyrazolo (3, 4-D) pyrimidin-4-one derivatives and their use as PDE9A mudulators for the treatment of CNS disorders
UA105362C2 (en) 2008-04-02 2014-05-12 Бьорингер Ингельхайм Интернациональ Гмбх 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
CA2736304A1 (en) 2008-09-08 2010-03-11 Boehringer Ingelheim International Gmbh Pyrazolopyrimidines and their use for the treatment of cns disorders
JP5763539B2 (en) 2008-10-24 2015-08-12 アイシス ファーマシューティカルズ， インコーポレーテッド 5 'and 2' bis-substituted nucleosides and oligomeric compounds produced therefrom
US8987435B2 (en) 2008-10-24 2015-03-24 Isis Pharmaceuticals, Inc. Oligomeric compounds and methods
PT2414363E (en) 2009-03-31 2014-02-26 Boehringer Ingelheim Int 1-heterocyclyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one derivatives and their use as pde9a modulators
EP2625186B1 (en) 2010-04-28 2016-07-27 Ionis Pharmaceuticals, Inc. 5' modified nucleosides and oligomeric compounds prepared therefrom
JP6005628B2 (en) 2010-04-28 2016-10-12 アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． Modified nucleosides, analogs thereof, and oligomeric compounds prepared therefrom
UA110347C2 (en) 2010-08-12 2015-12-25 Бьорінгер Інгельхайм Інтернаціональ Гмбх Derivative 6-cycloalkanes 1.5 dyhidropirazol [3,4-d] pyrimidine-4-one and their use as inhibitors pde9a
CN103209987B (en) 2010-09-22 2017-06-06 艾丽奥斯生物制药有限公司 Substituted nucleotide analog
US8809345B2 (en) 2011-02-15 2014-08-19 Boehringer Ingelheim International Gmbh 6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders
EP2794630A4 (en) 2011-12-22 2015-04-01 Alios Biopharma Inc Substituted phosphorothioate nucleotide analogs
CN104321333A (en) 2012-03-21 2015-01-28 沃泰克斯药物股份有限公司 Solid forms of a thiophosphoramidate nucleotide prodrug
NZ630805A (en) 2012-03-22 2016-01-29 Alios Biopharma Inc Pharmaceutical combinations comprising a thionucleotide analog
GB201700595D0 (en) * 2017-01-13 2017-03-01 Univ Oxford Innovation Ltd Oligonucleotide ligation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378825A (en) * 1990-07-27 1995-01-03 Isis Pharmaceuticals, Inc. Backbone modified oligonucleotide analogs
DK0741741T3 (en) * 1994-01-26 2002-12-23 Novartis Ag Modified oligonucleotides
EP0714907A1 (en) * 1994-11-30 1996-06-05 F. Hoffmann-La Roche Ag Oligoribonucleotides with amide backbone

Also Published As

Publication number Publication date
WO1998000434A1 (en) 1998-01-08
ZA975742B (en) 1997-12-29

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