AU3310189A - A monoclonal antibody against pseudomonas aeruginosa, the preparation and use thereof - Google Patents
A monoclonal antibody against pseudomonas aeruginosa, the preparation and use thereofInfo
- Publication number
- AU3310189A AU3310189A AU33101/89A AU3310189A AU3310189A AU 3310189 A AU3310189 A AU 3310189A AU 33101/89 A AU33101/89 A AU 33101/89A AU 3310189 A AU3310189 A AU 3310189A AU 3310189 A AU3310189 A AU 3310189A
- Authority
- AU
- Australia
- Prior art keywords
- monoclonal antibody
- pseudomonas aeruginosa
- preparation
- antibody against
- against pseudomonas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- General Physics & Mathematics (AREA)
- Oncology (AREA)
- Virology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
A monoclonal antibody (mAb) which cross-reacts with all 19 of the hitherto known Pseudomonas aeruginosa serotypes is described. The sequence of the variable regions is given. This mAb can be used as diagnostic aid, as active substance or as active substance carrier.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3813023A DE3813023A1 (en) | 1988-04-19 | 1988-04-19 | MONOCLONAL ANTIBODY AGAINST PSEUDOMONAS AERUGINOSA, ITS PRODUCTION AND USE |
DE3813023 | 1988-04-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU3310189A true AU3310189A (en) | 1989-10-26 |
AU622446B2 AU622446B2 (en) | 1992-04-09 |
Family
ID=6352325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU33101/89A Ceased AU622446B2 (en) | 1988-04-19 | 1989-04-18 | A monoclonal antibody against pseudomonas aeruginosa, the preparation and use thereof |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0338395B1 (en) |
JP (1) | JPH0213376A (en) |
KR (1) | KR890016165A (en) |
AT (1) | ATE116374T1 (en) |
AU (1) | AU622446B2 (en) |
DE (2) | DE3813023A1 (en) |
DK (1) | DK186289A (en) |
ES (1) | ES2065932T3 (en) |
FI (1) | FI891816A (en) |
PT (1) | PT90296B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU5675790A (en) * | 1989-05-09 | 1990-11-29 | Cetus Corporation | Human monoclonal antibodies to sero-specific determinants of gram-negative bacteria |
CA2038978A1 (en) * | 1990-04-06 | 1991-10-07 | Richard P. Darveau | Antibodies for the treatment and diagnosis of pseudomonas aeruginosa infections |
CA2627309A1 (en) * | 2005-10-28 | 2007-05-03 | Meiji Seika Kaisha, Ltd. | Pseudomonas aeruginosa outer membrane protein pa5158 |
EP2220247A4 (en) | 2007-11-16 | 2011-10-26 | Nuvelo Inc | Antibodies to lrp6 |
WO2011138391A1 (en) | 2010-05-06 | 2011-11-10 | Novartis Ag | Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies |
CA2798432A1 (en) | 2010-05-06 | 2011-11-10 | Novartis Ag | Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies |
SG11201401717VA (en) | 2011-11-04 | 2014-05-29 | Novartis Ag | Low density lipoprotein-related protein 6 (lrp6) - half life extender constructs |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0256713A3 (en) * | 1986-08-06 | 1989-02-15 | Merck & Co. Inc. | Therapeutic human antipseudomonas aeruginosa antibodies |
JPS63267295A (en) * | 1986-12-03 | 1988-11-04 | Sumitomo Chem Co Ltd | Human antibody, antibody gene and corresponding recombinant |
US4870161A (en) * | 1987-09-25 | 1989-09-26 | The United States Of America As Represented By The Department Of Health And Human Services | Reagents and probes for distinguishing and isolating different GTP-binding proteins |
DK8189A (en) * | 1988-01-12 | 1989-07-13 | Bunge Australia | ANTIGEN-ANTIBODY CONJUGATES, THEIR PREPARATION AND USE |
WO1990012088A1 (en) * | 1989-04-13 | 1990-10-18 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | MONOCLONAL ANTIBODIES TO HUMAN GLUTATHIONE S TRANSFERASE Pi |
-
1988
- 1988-04-19 DE DE3813023A patent/DE3813023A1/en not_active Withdrawn
-
1989
- 1989-04-12 EP EP89106463A patent/EP0338395B1/en not_active Expired - Lifetime
- 1989-04-12 ES ES89106463T patent/ES2065932T3/en not_active Expired - Lifetime
- 1989-04-12 AT AT89106463T patent/ATE116374T1/en not_active IP Right Cessation
- 1989-04-12 DE DE58908815T patent/DE58908815D1/en not_active Expired - Lifetime
- 1989-04-17 FI FI891816A patent/FI891816A/en not_active Application Discontinuation
- 1989-04-18 DK DK186289A patent/DK186289A/en not_active Application Discontinuation
- 1989-04-18 AU AU33101/89A patent/AU622446B2/en not_active Ceased
- 1989-04-18 KR KR1019890005050A patent/KR890016165A/en not_active Application Discontinuation
- 1989-04-18 PT PT90296A patent/PT90296B/en not_active IP Right Cessation
- 1989-04-19 JP JP1099924A patent/JPH0213376A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
FI891816A (en) | 1989-10-20 |
DE3813023A1 (en) | 1989-11-16 |
DK186289D0 (en) | 1989-04-18 |
DE58908815D1 (en) | 1995-02-09 |
AU622446B2 (en) | 1992-04-09 |
PT90296A (en) | 1989-11-10 |
ES2065932T3 (en) | 1995-03-01 |
EP0338395B1 (en) | 1994-12-28 |
KR890016165A (en) | 1989-11-28 |
EP0338395A2 (en) | 1989-10-25 |
PT90296B (en) | 1995-01-31 |
FI891816A0 (en) | 1989-04-17 |
JPH0213376A (en) | 1990-01-17 |
ATE116374T1 (en) | 1995-01-15 |
DK186289A (en) | 1989-12-18 |
EP0338395A3 (en) | 1990-03-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB2185266B (en) | Monoclonal antibodies cross-reactive and cross-protective against p. aeruginosa serotypes | |
AU7566991A (en) | Monoclonal antibody and immunoconjugates for the treatment and detection of b cell disorders | |
ES508637A0 (en) | "PROCEDURE FOR THE PREPARATION OF SULFATE ALDEHIDE D-PHENYLALANYL-L-ARGININE". | |
CA2093928A1 (en) | Monoclonal antibodies for detection and treatment of cancer | |
AU628948B2 (en) | Monoclonal antibodies (mabs) against tumor-associated antigens, the preparation and use thereof | |
AU2724492A (en) | Antibodies in immunosuppression | |
ZA846214B (en) | Monoclonal antibodies with specificity for membrane-associated antigens | |
AU7198291A (en) | Human monoclonal antibodies against rabies viruses, the production and the use thereof | |
AU3310189A (en) | A monoclonal antibody against pseudomonas aeruginosa, the preparation and use thereof | |
AU7160691A (en) | Monoclonal antibodies which neutralize hiv-1 infection and their anti-idiotypes | |
AU2456888A (en) | Monoclonal antibodies specific for HIV and hybridomas for their production | |
IE880976L (en) | Human tumour-associated antigen | |
EP0176365A3 (en) | Human monoclonal antibody and its preparation | |
AU616667B2 (en) | Monoclonal antibodies against e7 protein of human type 16 papillomavirus, a process for their preparation, and their use | |
AU584690B2 (en) | E87ag antigen of pseudomonas aeruginosa, monoclonal antibody against it, and hybridoma | |
AU1796692A (en) | Anti-idiotypic monoclonal antibodies for mucoid pseudomonas aeruginosa, their preparation and use | |
DE3860517D1 (en) | HERMETICALLY TIGHT ROTATIONAL TRANSMISSION DEVICE WITH METAL BELLOWS, ESPECIALLY FOR VALVES WITH SIMPLE 90 DEGREES. | |
NO903347D0 (en) | PROCEDURE FOR THE PREPARATION OF 14,17ALFA-ETHANO AND ETHANOESTRATRIAGES. | |
EP0327648A4 (en) | Human monoclonal antibody and drug for prophylaxis and treatment of infectious diseases comprising same as effective ingredient. | |
AU1626492A (en) | Monoclonal antibodies against the plasmin-antiplasmin complex, a method for the preparation thereof and the use thereof | |
AU6596390A (en) | Monoclonal antibodies cross-reactive and cross-protective against p. aeruginosa serotypes | |
CA2088370A1 (en) | New use of monoclonal antibody | |
EP0450573A3 (en) | Antibodies for the treatment and diagnosis of pseudomonas aeruginosa infections | |
AU3283693A (en) | Specific antibodies against activated platelets, the preparation thereof and the use thereof in diagnosis and therapy | |
AR243932A1 (en) | Hybridomas, procedure for their preparation, monoclonal antibodies, the procedure for their preparation and a compound for diagnosis based on the antibody. |