AU3064989A - Modified gene sequences encoding modified tpa and products therefrom - Google Patents
Modified gene sequences encoding modified tpa and products therefromInfo
- Publication number
- AU3064989A AU3064989A AU30649/89A AU3064989A AU3064989A AU 3064989 A AU3064989 A AU 3064989A AU 30649/89 A AU30649/89 A AU 30649/89A AU 3064989 A AU3064989 A AU 3064989A AU 3064989 A AU3064989 A AU 3064989A
- Authority
- AU
- Australia
- Prior art keywords
- sequence
- transfected
- host cell
- dna sequence
- cell transformed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15269188A | 1988-02-05 | 1988-02-05 | |
US152691 | 1988-02-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU3064989A true AU3064989A (en) | 1989-08-25 |
Family
ID=22543990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU30649/89A Abandoned AU3064989A (en) | 1988-02-05 | 1989-02-03 | Modified gene sequences encoding modified tpa and products therefrom |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0400054A1 (ja) |
JP (1) | JPH04500752A (ja) |
AU (1) | AU3064989A (ja) |
WO (1) | WO1989007145A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU619803B2 (en) * | 1988-02-05 | 1992-02-06 | Genzyme Corporation | Rearranged tissue plasminogen activators and method for producing same |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2047702C (en) * | 1989-03-06 | 2000-10-24 | Joseph F. Sambrook | Serpin resistant chymotrypsin superfamily proteases particularly pai-1 resistant t-pa, complementary inhibitor mutants; compositions; genes; expression |
US5866413A (en) * | 1989-03-06 | 1999-02-02 | Board Of Regents Of The University Of Texas System | Pai-1 mutants |
US5242688A (en) * | 1990-12-24 | 1993-09-07 | Eli Lilly And Company | Method of treating thromboembolic disorders by administration of diglycosylated t-pa variants |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1987003906A1 (en) * | 1985-12-20 | 1987-07-02 | The Upjohn Company | Tissue plasminogen activator (tpa) analogs |
-
1989
- 1989-02-03 WO PCT/US1989/000464 patent/WO1989007145A1/en not_active Application Discontinuation
- 1989-02-03 JP JP50240589A patent/JPH04500752A/ja active Pending
- 1989-02-03 EP EP19890902589 patent/EP0400054A1/en not_active Withdrawn
- 1989-02-03 AU AU30649/89A patent/AU3064989A/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU619803B2 (en) * | 1988-02-05 | 1992-02-06 | Genzyme Corporation | Rearranged tissue plasminogen activators and method for producing same |
Also Published As
Publication number | Publication date |
---|---|
WO1989007145A1 (en) | 1989-08-10 |
EP0400054A1 (en) | 1990-12-05 |
JPH04500752A (ja) | 1992-02-13 |
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