AU3063089A - Renin inhibiting peptides with polar end groups - Google Patents

Renin inhibiting peptides with polar end groups

Info

Publication number
AU3063089A
AU3063089A AU30630/89A AU3063089A AU3063089A AU 3063089 A AU3063089 A AU 3063089A AU 30630/89 A AU30630/89 A AU 30630/89A AU 3063089 A AU3063089 A AU 3063089A AU 3063089 A AU3063089 A AU 3063089A
Authority
AU
Australia
Prior art keywords
end groups
polar end
inhibiting peptides
renin inhibiting
renin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU30630/89A
Other versions
AU632468B2 (en
Inventor
Gordon L. Bundy
Jed F. Fisher
Jackson B. Hester Jr.
Michael F. Lipton
Norman A. Nelson
Suvit Thaisrivongs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU3063089A publication Critical patent/AU3063089A/en
Application granted granted Critical
Publication of AU632468B2 publication Critical patent/AU632468B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU30630/89A 1988-02-01 1989-01-27 Renin inhibiting peptides with polar end groups Expired - Fee Related AU632468B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15112988A 1988-02-01 1988-02-01
US151129 1988-02-01

Publications (2)

Publication Number Publication Date
AU3063089A true AU3063089A (en) 1989-08-25
AU632468B2 AU632468B2 (en) 1993-01-07

Family

ID=22537440

Family Applications (1)

Application Number Title Priority Date Filing Date
AU30630/89A Expired - Fee Related AU632468B2 (en) 1988-02-01 1989-01-27 Renin inhibiting peptides with polar end groups

Country Status (9)

Country Link
EP (2) EP0397779A1 (en)
JP (1) JPH03502328A (en)
KR (1) KR900700502A (en)
AU (1) AU632468B2 (en)
DK (1) DK183090A (en)
IL (1) IL89110A0 (en)
NZ (1) NZ227786A (en)
WO (1) WO1989007109A1 (en)
ZA (1) ZA89723B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2084150T3 (en) 1989-12-22 1996-05-01 Commw Scient Ind Res Org AMINO ACIDS, PEPTIDES OR THEIR DERIVATIVES ASSOCIATED WITH FATS.
US5583198A (en) * 1989-12-22 1996-12-10 Commonwealth Scientific And Industrial Research Organization Amino acids, peptides or derivatives thereof coupled to fats
DE4037437A1 (en) * 1990-11-24 1992-05-27 Hoechst Ag Amino diol DERIVATIVES
US5691368A (en) * 1995-01-11 1997-11-25 Hoechst Marion Roussel, Inc. Substituted oxazolidine calpain and/or cathepsin B inhibitors
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
US7026289B2 (en) 1997-05-13 2006-04-11 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Method and compositions for treating hyperlipidemia and other conditions
DK0981363T3 (en) 1997-05-13 2003-12-01 Sod Conseils Rech Applic Somatostatin agonists for reducing body weight
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
DK1401863T3 (en) 2001-06-08 2009-05-25 Ipsen Pharma Chimeric somatostatin-dopamine analogues
US20080207527A1 (en) * 2004-09-17 2008-08-28 Comentis, Inc. Bicyclic Compounds Which Inhibit Beta-Secretase Activity and Methods of Use Thereof
KR20080015079A (en) 2005-04-08 2008-02-18 코멘티스, 인코포레이티드 Compounds which inhibit beta-secretase activity and methods of use thereof
CN107446053A (en) 2008-06-12 2017-12-08 益普生生物创新有限公司 The suppression of cancer
KR101642363B1 (en) 2008-06-12 2016-07-25 입센 바이오이노베이션 리미티드 Suppression of neuroendocrine diseases
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
AU2014280847B2 (en) 2013-06-13 2019-07-04 Antisense Therapeutics Ltd Combination therapy
CN108558685B (en) * 2017-06-08 2020-11-20 西安力邦制药有限公司 2, 6-disubstituted phenol meglumine derivative and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0163237A3 (en) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
EP0486478A3 (en) * 1984-08-06 1992-08-12 The Upjohn Company Renin-inhibiting peptides
US4729985A (en) * 1985-08-09 1988-03-08 Pfizer Inc. Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
NL8800100A (en) * 1987-01-21 1988-08-16 Sandoz Ag NEW PEPTIDE DERIVATIVES AND METHODS FOR PREPARING AND USING THESE DERIVATIVES.

Also Published As

Publication number Publication date
JPH03502328A (en) 1991-05-30
DK183090D0 (en) 1990-07-31
KR900700502A (en) 1990-08-13
EP0397779A1 (en) 1990-11-22
ZA89723B (en) 1989-10-25
IL89110A0 (en) 1989-08-15
DK183090A (en) 1990-09-14
EP0329295A1 (en) 1989-08-23
AU632468B2 (en) 1993-01-07
WO1989007109A1 (en) 1989-08-10
NZ227786A (en) 1992-02-25

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