AU3053489A - Rearranged tissue plasminogen activators and method for producing same - Google Patents

Rearranged tissue plasminogen activators and method for producing same

Info

Publication number
AU3053489A
AU3053489A AU30534/89A AU3053489A AU3053489A AU 3053489 A AU3053489 A AU 3053489A AU 30534/89 A AU30534/89 A AU 30534/89A AU 3053489 A AU3053489 A AU 3053489A AU 3053489 A AU3053489 A AU 3053489A
Authority
AU
Australia
Prior art keywords
rearranged
tissue plasminogen
producing same
plasminogen activators
activators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU30534/89A
Other versions
AU619803B2 (en
Inventor
David J. Livingston
William Markland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Integrated Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Integrated Genetics Inc filed Critical Integrated Genetics Inc
Priority claimed from PCT/US1989/000465 external-priority patent/WO1989007146A1/en
Publication of AU3053489A publication Critical patent/AU3053489A/en
Assigned to GENZYME CORPORATION reassignment GENZYME CORPORATION Alteration of Name(s) of Applicant(s) under S113 Assignors: INTEGRATED GENETICS INC.
Application granted granted Critical
Publication of AU619803B2 publication Critical patent/AU619803B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
AU30534/89A 1988-02-05 1989-02-03 Rearranged tissue plasminogen activators and method for producing same Expired - Fee Related AU619803B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15269288A 1988-02-05 1988-02-05
US152692 1988-02-05
PCT/US1989/000465 WO1989007146A1 (en) 1988-02-05 1989-02-03 Rearranged tissue plasminogen activators and method for producing same

Publications (2)

Publication Number Publication Date
AU3053489A true AU3053489A (en) 1989-08-25
AU619803B2 AU619803B2 (en) 1992-02-06

Family

ID=26779361

Family Applications (1)

Application Number Title Priority Date Filing Date
AU30534/89A Expired - Fee Related AU619803B2 (en) 1988-02-05 1989-02-03 Rearranged tissue plasminogen activators and method for producing same

Country Status (1)

Country Link
AU (1) AU619803B2 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU600463B2 (en) * 1985-12-20 1990-08-16 Pharmacia & Upjohn Company Tissue plasminogen activator (tpa) analogs
WO1989007145A1 (en) * 1988-02-05 1989-08-10 Integrated Genetics, Inc. Modified gene sequences encoding modified tpa and products therefrom

Also Published As

Publication number Publication date
AU619803B2 (en) 1992-02-06

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