AU2900389A - Transgenic testing systems for mutagens and carcinogens - Google Patents
Transgenic testing systems for mutagens and carcinogensInfo
- Publication number
- AU2900389A AU2900389A AU29003/89A AU2900389A AU2900389A AU 2900389 A AU2900389 A AU 2900389A AU 29003/89 A AU29003/89 A AU 29003/89A AU 2900389 A AU2900389 A AU 2900389A AU 2900389 A AU2900389 A AU 2900389A
- Authority
- AU
- Australia
- Prior art keywords
- mutagens
- carcinogens
- testing systems
- transgenic
- transgenic testing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 231100000357 carcinogen Toxicity 0.000 title 1
- 239000003183 carcinogenic agent Substances 0.000 title 1
- 239000003471 mutagenic agent Substances 0.000 title 1
- 231100000707 mutagenic chemical Toxicity 0.000 title 1
- 230000009261 transgenic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
- G01N33/5017—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/30—Animal model comprising expression system for selective cell killing, e.g. toxins, enzyme dependent prodrug therapy using ganciclovir
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13238387A | 1987-12-15 | 1987-12-15 | |
US132383 | 1987-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2900389A true AU2900389A (en) | 1989-07-19 |
Family
ID=22453778
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU29003/89A Abandoned AU2900389A (en) | 1987-12-15 | 1988-12-08 | Transgenic testing systems for mutagens and carcinogens |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0390857A4 (en) |
JP (1) | JPH03502882A (en) |
KR (1) | KR900700621A (en) |
AU (1) | AU2900389A (en) |
WO (1) | WO1989005864A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991015116A1 (en) * | 1990-03-30 | 1991-10-17 | Amrad Corporation Limited | Doubly transgenic animals |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0370813A3 (en) * | 1988-11-25 | 1991-06-19 | Exemplar Corporation | Rapid screening mutagenesis and teratogenesis assay |
US5174986A (en) * | 1989-07-05 | 1992-12-29 | Genpharm International, Inc. | Method for determining oncogenic potential of a chemical compound |
CA2351200A1 (en) * | 1989-12-01 | 1991-06-13 | Gene Pharming Europe Bv | Production of recombinant polypeptides by bovine species and transgenic methods |
GB9003791D0 (en) * | 1990-02-20 | 1990-04-18 | Ludwig Inst Cancer Res | Transgenic animals,cell lines therefrom,and their use |
US5569824A (en) * | 1991-01-04 | 1996-10-29 | Baylor College Of Medicine | Transgenic mice containing a disrupted p53 gene |
AU1236092A (en) * | 1991-01-04 | 1992-08-17 | Baylor College Of Medicine | Tumor susceptible non-human animals |
US5866759A (en) * | 1991-02-20 | 1999-02-02 | Ludwig Institute For Cancer Research | Transgenic mice expressing TSSV40 large T antigen |
GB9113097D0 (en) * | 1991-06-18 | 1991-08-07 | Boehringer Ingelheim Int | Chimeric gene |
WO1993017123A1 (en) * | 1992-02-27 | 1993-09-02 | Ohio University | Mutagenicity testing using reporter genes with modified methylation frequencies |
AU4240293A (en) * | 1992-05-08 | 1993-12-13 | Exemplar Corporation | Anti-neoplastic in vivo drug screen |
DE19525285C2 (en) * | 1995-06-28 | 1999-04-15 | Inst Pflanzengenetik & Kultur | In vitro test procedure for the detection of chemical-induced embryotoxic / teratogenic effects |
GB9707141D0 (en) * | 1997-04-08 | 1997-05-28 | Inst Of Food Research | Biological assay |
US6063359A (en) * | 1997-09-26 | 2000-05-16 | Washington University | Method for determining oncogenic activity of a substance |
DE19818422A1 (en) * | 1998-04-24 | 1999-10-28 | Stefan Harjes | Method for determining absolute mutagenicity and error rate of polymerases in amplification reactions |
WO2001090339A2 (en) * | 2000-05-23 | 2001-11-29 | Warner-Lambert Company | Methods and compositions to activate genes in cells |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1466256A (en) * | 1973-06-20 | 1977-03-02 | Grindstedvaerket As | 2,5-substituted furans and their production |
US4302535A (en) * | 1979-09-27 | 1981-11-24 | Massachusetts Institute Of Technology | Assay for mutagenesis in heterozygous diploid human lymphoblasts |
IL62479A (en) * | 1981-03-25 | 1984-11-30 | Yeda Res & Dev | Assay for the determination of carcinogenicity |
US4792520A (en) * | 1984-02-16 | 1988-12-20 | University Of Cincinnati | Methods and kits for identifying mutagenic agents and molecular mutations in DNA in mammalian cells |
US4736866A (en) * | 1984-06-22 | 1988-04-12 | President And Fellows Of Harvard College | Transgenic non-human mammals |
DE3681738D1 (en) * | 1986-10-15 | 1991-10-31 | Battelle Memorial Institute, Carouge, Genf/Geneve, Ch | |
ATE132266T1 (en) * | 1987-05-01 | 1996-01-15 | Stratagene Inc | MUTAGENEOSIS TESTING USING NON-HUMAN LIVING BEINGS CONTAINING TEST DNA SEQUENCES |
WO1989009272A1 (en) * | 1988-03-22 | 1989-10-05 | Chemical Industry Institute Of Toxicology | A transgenic mouse for measurement and characterization of mutation induction in vivo |
ZA892518B (en) * | 1988-04-08 | 1989-12-27 | Intracel Corp | Method for the in-vivo production and testing of proteins by recombinant gene expression in selected host-cells |
EP0370813A3 (en) * | 1988-11-25 | 1991-06-19 | Exemplar Corporation | Rapid screening mutagenesis and teratogenesis assay |
-
1988
- 1988-12-08 AU AU29003/89A patent/AU2900389A/en not_active Abandoned
- 1988-12-08 WO PCT/US1988/004382 patent/WO1989005864A1/en not_active Application Discontinuation
- 1988-12-08 JP JP1500889A patent/JPH03502882A/en active Pending
- 1988-12-08 EP EP19890901002 patent/EP0390857A4/en not_active Withdrawn
-
1989
- 1989-08-16 KR KR1019890701537A patent/KR900700621A/en not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991015116A1 (en) * | 1990-03-30 | 1991-10-17 | Amrad Corporation Limited | Doubly transgenic animals |
Also Published As
Publication number | Publication date |
---|---|
JPH03502882A (en) | 1991-07-04 |
EP0390857A1 (en) | 1990-10-10 |
WO1989005864A1 (en) | 1989-06-29 |
EP0390857A4 (en) | 1991-04-17 |
KR900700621A (en) | 1990-08-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB2212016B (en) | Calibration system | |
AU1541788A (en) | System for isolating and identifying leukocytes | |
GB8819032D0 (en) | Independent wheel-suspension system | |
GB8900949D0 (en) | Function inspecting system | |
AU2900389A (en) | Transgenic testing systems for mutagens and carcinogens | |
GB8706125D0 (en) | Checking system configuration | |
GB2202641B (en) | Recording systems | |
GB8804169D0 (en) | Aids prognosis test | |
AU6887287A (en) | Signal distribution system for selective testing | |
AU2486488A (en) | Automatic measurement system | |
GB8806894D0 (en) | Braking-power amplifier | |
KR900008756B1 (en) | Amplifier | |
GB8729515D0 (en) | Signal receiving arrangement | |
GB2209894B (en) | Signal amplifier | |
GB8721287D0 (en) | R f signal distribution | |
KR960009738B1 (en) | Amplifier | |
EP0320779A3 (en) | Sense amplifier | |
GB8715676D0 (en) | Solenoid system | |
GB2211305B (en) | Flow tester | |
HK66696A (en) | Recording and evaluating system for cue signals | |
GB8828560D0 (en) | Resilience testing | |
GB8724932D0 (en) | Analysing signals | |
AU2717488A (en) | Ectoparasiticides | |
HUT49410A (en) | Gluten-enteropathy test | |
EP0338316A3 (en) | Bandpass amplifier |