AU2857889A - Method for producing affino-enzymatic compounds for visual indication of cholesterol on skin surface based on cholesterol affinant detecting agent and visualizing agent and application thereof - Google Patents

Method for producing affino-enzymatic compounds for visual indication of cholesterol on skin surface based on cholesterol affinant detecting agent and visualizing agent and application thereof

Info

Publication number
AU2857889A
AU2857889A AU28578/89A AU2857889A AU2857889A AU 2857889 A AU2857889 A AU 2857889A AU 28578/89 A AU28578/89 A AU 28578/89A AU 2857889 A AU2857889 A AU 2857889A AU 2857889 A AU2857889 A AU 2857889A
Authority
AU
Australia
Prior art keywords
cholesterol
agent
affino
affinant
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU28578/89A
Other versions
AU615709B2 (en
Inventor
Irina Pavlovna Adrianova
Lev Alexandrovich Andrianov
Dmitry-Borisovich Gudkov
Jury Mikhailovich Lopukhin
Alexandr Borisovich Rabovsky
Viktor Vikrotovich Zuevsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NAUCHNO-ISSLEDOVATELSKY INSTITUT FIZIKO-KHIMICHESKOI MEDITSINY
Original Assignee
NII FIZ KHIM MEDITSINY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NII FIZ KHIM MEDITSINY filed Critical NII FIZ KHIM MEDITSINY
Publication of AU2857889A publication Critical patent/AU2857889A/en
Application granted granted Critical
Publication of AU615709B2 publication Critical patent/AU615709B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Used as detecting agent A are steroid glycosides, triterpene glycosides, hydrophobic proteins, proteinaceous toxins or polyene antibiotics which have an affinity for cholesterol, and as visualisation agent B are enzymes. To increase the sensitivity of the prepared compounds, the detecting agent A and the visualisation agent B are immobilised on a crosslinking agent C, for which low or high molecular weight compounds are used. <IMAGE>
AU28578/89A 1988-01-19 1989-01-18 Method for producing affino-enzymatic compounds for visual indication of cholesterol on skin surface based on cholesterol affinant detecting agent and visualizing agent and application thereof Expired - Fee Related AU615709B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU884357046A SU1675769A1 (en) 1988-01-19 1988-01-19 Method for preparation of agent, used for visual detection of cholesterol on the skin surface

Publications (2)

Publication Number Publication Date
AU2857889A true AU2857889A (en) 1989-07-20
AU615709B2 AU615709B2 (en) 1991-10-10

Family

ID=21347013

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28578/89A Expired - Fee Related AU615709B2 (en) 1988-01-19 1989-01-18 Method for producing affino-enzymatic compounds for visual indication of cholesterol on skin surface based on cholesterol affinant detecting agent and visualizing agent and application thereof

Country Status (13)

Country Link
EP (1) EP0338189B1 (en)
JP (1) JPH01289498A (en)
CN (1) CN1048925A (en)
AT (1) ATE137336T1 (en)
AU (1) AU615709B2 (en)
CA (1) CA1335968C (en)
CS (1) CS274496B2 (en)
DD (1) DD289604A5 (en)
DE (1) DE58909664D1 (en)
FI (1) FI890266A (en)
HU (1) HUT56973A (en)
PL (1) PL277263A1 (en)
SU (2) SU1675769A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5489510A (en) * 1988-01-19 1996-02-06 2860601 Canada Inc. Method for visual indication of cholesterol on skin surface agents used therefor and methods for producing such agents
RU94044169A (en) * 1994-12-16 1996-10-20 И.А. Кочетов Multiple analytical member
LT4121B (en) 1995-06-01 1997-03-25 Akcine Bendrove Biofa Kit for the cholesterol vizualization on the skin and process for preparing conjugate for use in cholesterol determination
RU2130189C1 (en) * 1997-02-20 1999-05-10 Александр Сергеевич Парфенов Method for determining tissular cholesterol in skin
CA2465427A1 (en) * 2004-04-28 2005-10-28 Imi International Medical Innovations Inc. Direct assay of cholesterol in skin samples removed by tape stripping
CN100564539C (en) * 2004-12-31 2009-12-02 浙江伊利康生物技术有限公司 The mensuration reagent and the preparation method of cholesterol in the high-density lipoprotein (HDL)
CN104181312B (en) * 2014-08-08 2016-06-01 安徽易康达光电科技有限公司 A kind of skin free cholesterol noninvasive detection device for atherosclerosis risk assessment

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071020A (en) * 1976-06-03 1978-01-31 Xienta, Inc. Apparatus and methods for performing in-vivo measurements of enzyme activity
US4401122A (en) * 1979-08-02 1983-08-30 Children's Hospital Medical Center Cutaneous methods of measuring body substances
US4458686A (en) * 1979-08-02 1984-07-10 Children's Hospital Medical Center Cutaneous methods of measuring body substances
EP0118543A1 (en) * 1982-09-01 1984-09-19 University Of Southern California Substituted n-benzenesulfonyloxyphthalimides

Also Published As

Publication number Publication date
EP0338189B1 (en) 1996-04-24
FI890266A (en) 1989-07-20
JPH01289498A (en) 1989-11-21
CS274496B2 (en) 1991-04-11
PL277263A1 (en) 1989-09-04
CS34889A2 (en) 1990-08-14
SU1675770A1 (en) 1991-09-07
FI890266A0 (en) 1989-01-18
EP0338189A3 (en) 1990-05-02
AU615709B2 (en) 1991-10-10
DE58909664D1 (en) 1996-05-30
HUT56973A (en) 1991-10-28
CA1335968C (en) 1995-06-20
CN1048925A (en) 1991-01-30
ATE137336T1 (en) 1996-05-15
SU1675769A1 (en) 1991-09-07
DD289604A5 (en) 1991-05-02
EP0338189A2 (en) 1989-10-25

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