AU2818200A - Homology models of the glucocorticoid receptor - Google Patents

Homology models of the glucocorticoid receptor

Info

Publication number
AU2818200A
AU2818200A AU28182/00A AU2818200A AU2818200A AU 2818200 A AU2818200 A AU 2818200A AU 28182/00 A AU28182/00 A AU 28182/00A AU 2818200 A AU2818200 A AU 2818200A AU 2818200 A AU2818200 A AU 2818200A
Authority
AU
Australia
Prior art keywords
glucocorticoid receptor
homology models
homology
models
glucocorticoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU28182/00A
Inventor
Mikael Gillner
Paulette Greenidge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Karo Pharma AB
Original Assignee
Karo Bio AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9904441.4A external-priority patent/GB9904441D0/en
Priority claimed from GBGB9909151.4A external-priority patent/GB9909151D0/en
Application filed by Karo Bio AB filed Critical Karo Bio AB
Publication of AU2818200A publication Critical patent/AU2818200A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/20Protein or domain folding

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
AU28182/00A 1999-03-01 2000-03-01 Homology models of the glucocorticoid receptor Abandoned AU2818200A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9904441 1999-03-01
GBGB9904441.4A GB9904441D0 (en) 1999-03-01 1999-03-01 Homology models of the glucocorticoid receptor
GBGB9909151.4A GB9909151D0 (en) 1999-04-22 1999-04-22 Homology models of the glucocorticoid receptor
GB9909151 1999-04-22
PCT/GB2000/000727 WO2000052050A2 (en) 1999-03-01 2000-03-01 Homology models of the glucocorticoid receptor

Publications (1)

Publication Number Publication Date
AU2818200A true AU2818200A (en) 2000-09-21

Family

ID=26315184

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28182/00A Abandoned AU2818200A (en) 1999-03-01 2000-03-01 Homology models of the glucocorticoid receptor

Country Status (2)

Country Link
AU (1) AU2818200A (en)
WO (1) WO2000052050A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020197670A1 (en) * 2001-06-22 2002-12-26 Price Thomas M. Membrane associated progesterone receptor
AU2002355929A1 (en) * 2001-07-17 2003-03-03 Smithkline Beecham Corporation Crystallized glucocorticoid receptor ligand binding domain polypeptide and screening methods employing same
GB0209507D0 (en) * 2002-04-25 2002-06-05 Karobio Ab Nuclear receptor structure
EP1375517A1 (en) * 2002-06-21 2004-01-02 Smithkline Beecham Corporation Structure of a glucocorticoid receptor ligand binding domain comprising an expanded binding pocket and methods employing same
DE60331103D1 (en) * 2002-07-18 2010-03-11 Bristol Myers Squibb Co COMPOSITIONS AND METHODS RELATED TO THE NUCLEAR HORMON RECEPTOR POT II

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0873361B1 (en) * 1995-12-13 2006-11-02 The Regents Of The University Of California Crystals of the ligand-binding domain of the thyroid hormone receptor complexed to a ligand
US6266622B1 (en) * 1995-12-13 2001-07-24 Regents Of The University Of California Nuclear receptor ligands and ligand binding domains
EP0980386A2 (en) * 1997-06-10 2000-02-23 Karo Bio Ab Estrogen receptor crystals and ligands
CA2324060A1 (en) * 1998-03-30 1999-10-07 The Regents Of The University Of California Methods and compounds for modulating nuclear receptor activity

Also Published As

Publication number Publication date
WO2000052050A2 (en) 2000-09-08
WO2000052050A3 (en) 2000-12-28

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase