AU2657597A - Use of allosteric haemoglobin modifier for treating solid tumors and inhibiting tumor metastases - Google Patents

Use of allosteric haemoglobin modifier for treating solid tumors and inhibiting tumor metastases

Info

Publication number
AU2657597A
AU2657597A AU26575/97A AU2657597A AU2657597A AU 2657597 A AU2657597 A AU 2657597A AU 26575/97 A AU26575/97 A AU 26575/97A AU 2657597 A AU2657597 A AU 2657597A AU 2657597 A AU2657597 A AU 2657597A
Authority
AU
Australia
Prior art keywords
haemoglobin
allosteric
modifier
solid tumors
inhibiting tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU26575/97A
Inventor
Beverly A Teicher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dana Farber Cancer Institute Inc
Original Assignee
Dana Farber Cancer Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Institute Inc filed Critical Dana Farber Cancer Institute Inc
Publication of AU2657597A publication Critical patent/AU2657597A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU26575/97A 1996-03-21 1997-03-21 Use of allosteric haemoglobin modifier for treating solid tumors and inhibiting tumor metastases Abandoned AU2657597A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1381896P 1996-03-21 1996-03-21
US60013818 1996-03-21
PCT/US1997/003465 WO1997034594A2 (en) 1996-03-21 1997-03-21 Use of allosteric haemoglobin modifier for treating solid tumors and inhibiting tumor metastases

Publications (1)

Publication Number Publication Date
AU2657597A true AU2657597A (en) 1997-10-10

Family

ID=21761928

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26575/97A Abandoned AU2657597A (en) 1996-03-21 1997-03-21 Use of allosteric haemoglobin modifier for treating solid tumors and inhibiting tumor metastases

Country Status (2)

Country Link
AU (1) AU2657597A (en)
WO (1) WO1997034594A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1381311A4 (en) 2001-02-23 2005-04-27 Allos Therapeutics Inc Methods and reagents to acquire mri signals and images
US20070293698A1 (en) 2004-04-22 2007-12-20 Allos Therapeutics, Inc. Compositions of Allosteric Hemoglobin Modifiers and Methods of Making the Same
EP3092213B1 (en) * 2013-12-27 2019-10-23 Virginia Commonwealth University Allosteric hemoglobin modifiers with nitric oxide releasing moiety

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248785A (en) * 1990-02-12 1993-09-28 Virginia Commonwealth University Using allosteric hemoglobin modifiers to decrease oxygen affinity in blood
US5432191A (en) * 1990-02-12 1995-07-11 The Center For Innovative Technology Allosteric hemoglobin modifiers to decrease oxygen affinity in blood

Also Published As

Publication number Publication date
WO1997034594A3 (en) 1997-12-24
WO1997034594A2 (en) 1997-09-25

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