AU2557188A - Adheson variants - Google Patents

Adheson variants

Info

Publication number
AU2557188A
AU2557188A AU25571/88A AU2557188A AU2557188A AU 2557188 A AU2557188 A AU 2557188A AU 25571/88 A AU25571/88 A AU 25571/88A AU 2557188 A AU2557188 A AU 2557188A AU 2557188 A AU2557188 A AU 2557188A
Authority
AU
Australia
Prior art keywords
adheson
variants
adheson variants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU25571/88A
Other versions
AU618969B2 (en
Inventor
Daniel J. Capon
Timothy J. Gregory
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Priority claimed from PCT/US1988/003414 external-priority patent/WO1989002922A1/en
Publication of AU2557188A publication Critical patent/AU2557188A/en
Application granted granted Critical
Publication of AU618969B2 publication Critical patent/AU618969B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70514CD4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/32Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/55Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
AU25571/88A 1987-10-02 1988-10-03 Adheson variants Expired AU618969B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10432987A 1987-10-02 1987-10-02
US104329 1987-10-02
US25078588A 1988-09-28 1988-09-28
US250785 1988-09-28
PCT/US1988/003414 WO1989002922A1 (en) 1987-10-02 1988-10-03 Adheson variants

Publications (2)

Publication Number Publication Date
AU2557188A true AU2557188A (en) 1989-04-18
AU618969B2 AU618969B2 (en) 1992-01-16

Family

ID=27375846

Family Applications (1)

Application Number Title Priority Date Filing Date
AU25571/88A Expired AU618969B2 (en) 1987-10-02 1988-10-03 Adheson variants

Country Status (1)

Country Link
AU (1) AU618969B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2065010A1 (en) * 1989-08-23 1991-02-24 Brian Seed Non-human primate cd4 polypeptides, fusions thereof, dna encoding, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3751751T2 (en) * 1986-08-21 1996-10-17 Univ Columbia DNA ENCODING THE T CELL SURFACE PROTEIN T4 AND USE OF T4 FRAGMENTS IN THE TREATMENT OF AIDS

Also Published As

Publication number Publication date
AU618969B2 (en) 1992-01-16

Similar Documents

Publication Publication Date Title
AU614965B2 (en) Thiadiazinones
AU583762B2 (en) Piperazinyl-heterocyclic compounds
AU1249788A (en) Structural element
AU2611588A (en) New phenylethanolamines
AU2204688A (en) Improved system
AU1407388A (en) Substituted di-t-butylphenols
AU2222388A (en) Peptidylheterocycles
AU1381888A (en) Timeswitches
AU1301788A (en) Chemo-radio-immuno-conjugates
AU2050788A (en) Chocolate
AU2084888A (en) Platewarmer system
AU2142288A (en) New aluminium-magnesium-hydroxy-compounds
AU1764488A (en) Substituted 5-methylamino-1-arylpyrazoles
AU1210388A (en) Novel aminohydrocarbyl-substituted ketoximosilanes
AU2665388A (en) 17-methylene-and 17-ethylidene-estratrienes
AU1590788A (en) Leukaemia-inhibitory factor
AU2142888A (en) Novel complex
AU1158888A (en) Scraper-spreader
AU578867B1 (en) Tack-off assembly
AU2586688A (en) Moth- and beetle-proofing agents
AU1366388A (en) Videosystem
AU2505988A (en) 3-aminopyrazolin-5-ones
AU2021888A (en) Sulphonylaminoguanidinoazines
AU2698888A (en) Naphthothiazepinones
AU2456688A (en) Dripulator