AU2555592A - Method for synthesizing glucuronides of 4,5-epoxy morphinanes - Google Patents

Method for synthesizing glucuronides of 4,5-epoxy morphinanes

Info

Publication number
AU2555592A
AU2555592A AU25555/92A AU2555592A AU2555592A AU 2555592 A AU2555592 A AU 2555592A AU 25555/92 A AU25555/92 A AU 25555/92A AU 2555592 A AU2555592 A AU 2555592A AU 2555592 A AU2555592 A AU 2555592A
Authority
AU
Australia
Prior art keywords
morphinanes
glucuronides
synthesizing
epoxy
synthesizing glucuronides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU25555/92A
Inventor
Alfred Adophe Henri Mertz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IREPA (INSTITUT REGIONAL DE PROMOTION de la RECHERCHE APPLIQUEE)
Original Assignee
IREPA (INSTITUT REGIONAL DE PROMOTION de la RECHERCHE APPLIQUEE)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IREPA (INSTITUT REGIONAL DE PROMOTION de la RECHERCHE APPLIQUEE) filed Critical IREPA (INSTITUT REGIONAL DE PROMOTION de la RECHERCHE APPLIQUEE)
Publication of AU2555592A publication Critical patent/AU2555592A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU25555/92A 1991-09-04 1992-09-04 Method for synthesizing glucuronides of 4,5-epoxy morphinanes Abandoned AU2555592A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9110927 1991-09-04
FR9110927A FR2680786B1 (en) 1991-09-04 1991-09-04 PROCESS FOR THE SYNTHESIS OF GLUCURONIDES OF 4,5-EPOXY MORPHINANES.

Publications (1)

Publication Number Publication Date
AU2555592A true AU2555592A (en) 1993-04-05

Family

ID=9416616

Family Applications (1)

Application Number Title Priority Date Filing Date
AU25555/92A Abandoned AU2555592A (en) 1991-09-04 1992-09-04 Method for synthesizing glucuronides of 4,5-epoxy morphinanes

Country Status (4)

Country Link
EP (1) EP0602151A1 (en)
AU (1) AU2555592A (en)
FR (1) FR2680786B1 (en)
WO (1) WO1993005057A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU672365B2 (en) * 1991-08-06 1996-10-03 Cenes Limited A process for making morphine-6-glucuronide or substituted morphine-6-glucuronide

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977326A (en) * 1991-08-06 1999-11-02 Salford Ultrafine Chemicals And Research Limited Process for making morphine-6-glucuronide or substituted morphine-6-glucuronide
GB9325065D0 (en) * 1993-12-07 1994-02-02 Salford Ultrafine Chem & Res An enzymatic process for making morphine-6-glucuronide or substituted morphine-6-glucuronide
DE4403709A1 (en) * 1994-02-07 1995-08-10 Lohmann Therapie Syst Lts Pharmaceutical composition for systemic transdermal administration with the active ingredient morphine-6-glucuronide
AT403162B (en) * 1995-10-11 1997-11-25 Nycomed Austria Gmbh NEW MORPHINE-6-GLUCURONIDE CRYSTAL SHAPE
DE19541921A1 (en) * 1995-11-10 1997-05-15 Nycomed Arzneimittel Gmbh New crystalline form of morphone-6-glucuronide, useful as analgesic
EP0816375A1 (en) * 1995-11-29 1998-01-07 Rolabo Sl Glycoconjugates of opiated substances
US5908927A (en) * 1996-05-22 1999-06-01 High Standard Products Corporation Synthesis of deuterated opiate glucuronides
GB9711118D0 (en) * 1997-05-29 1997-07-23 Rolabo Sl Compound
HUP0100841A3 (en) * 1998-02-02 2003-03-28 Cenes Ltd Cambridge Glycosidation of 4,5-epoxymorphinan-6-ols
PL344141A1 (en) 1998-05-13 2001-10-08 Cenes Ltd Process for preparation of 4,5-epoxymorphinan-6-oxyglucuronides
IL139773A0 (en) * 1998-06-06 2002-02-10 Cenes Ltd Morphine-6-glucuronide synthesis
US6740641B2 (en) * 2001-07-27 2004-05-25 Euro-Celtique, S.A. Sugar derivatives of hydromorphone, dihydromorphine and dihydromorphine, compositions thereof and uses for treating or preventing pain
GB0218811D0 (en) * 2002-08-14 2002-09-18 Cenes Ltd Salts of morphine-6-glucuronide
CN103421063B (en) * 2012-05-23 2016-04-06 宜昌人福药业有限责任公司 A kind of method of synthesizing morphine-6-β-D-Glucose aldehydic acid glycosides
EP3528873A2 (en) 2016-10-21 2019-08-28 Somniferum Labs LLC Apparatus for controlled delivery of opioid and other medications
CN108727444B (en) * 2017-04-19 2020-10-23 宜昌人福药业有限责任公司 Synthesis method of morphine-6-beta-D-glucuronide and intermediate compound thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2058243T3 (en) * 1988-01-12 1994-11-01 Baker Norton Pharma DERIVATIVES OF THE GLUCURONIC ACID FROM OPIACEAN ANTAGONISTS.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU672365B2 (en) * 1991-08-06 1996-10-03 Cenes Limited A process for making morphine-6-glucuronide or substituted morphine-6-glucuronide

Also Published As

Publication number Publication date
FR2680786B1 (en) 1995-03-10
EP0602151A1 (en) 1994-06-22
FR2680786A1 (en) 1993-03-05
WO1993005057A1 (en) 1993-03-18

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