AU2456792A - 2-hydroxymethylpyridines, the corresponding pyridine n-oxides and their derivatives, processes for their preparation and their use - Google Patents

2-hydroxymethylpyridines, the corresponding pyridine n-oxides and their derivatives, processes for their preparation and their use

Info

Publication number
AU2456792A
AU2456792A AU24567/92A AU2456792A AU2456792A AU 2456792 A AU2456792 A AU 2456792A AU 24567/92 A AU24567/92 A AU 24567/92A AU 2456792 A AU2456792 A AU 2456792A AU 2456792 A AU2456792 A AU 2456792A
Authority
AU
Australia
Prior art keywords
hydroxymethylpyridines
oxides
derivatives
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU24567/92A
Inventor
Martin Bickel
Kurt Kesseler
Bernd Scharbert
Klaus Weidmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU2456792A publication Critical patent/AU2456792A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AU24567/92A 1991-09-19 1992-09-18 2-hydroxymethylpyridines, the corresponding pyridine n-oxides and their derivatives, processes for their preparation and their use Abandoned AU2456792A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4131219 1991-09-19
DE4131219 1991-09-19
DE4136346 1991-11-05
DE4136346 1991-11-05

Publications (1)

Publication Number Publication Date
AU2456792A true AU2456792A (en) 1993-03-25

Family

ID=25907490

Family Applications (1)

Application Number Title Priority Date Filing Date
AU24567/92A Abandoned AU2456792A (en) 1991-09-19 1992-09-18 2-hydroxymethylpyridines, the corresponding pyridine n-oxides and their derivatives, processes for their preparation and their use

Country Status (7)

Country Link
EP (1) EP0533130A1 (en)
JP (1) JPH05213883A (en)
AU (1) AU2456792A (en)
CA (1) CA2078590A1 (en)
FI (1) FI924164A (en)
IL (1) IL103206A0 (en)
NO (1) NO923638L (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103037693A (en) * 2010-05-24 2013-04-10 范德比尔特大学 Substituted-6-methylnicotinamides as MGLUR5 positive allosteric modulators

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0567997A1 (en) * 1992-04-30 1993-11-03 Hoechst Aktiengesellschaft 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical
TW200409629A (en) 2002-06-27 2004-06-16 Bristol Myers Squibb Co 2,4-disubstituted-pyridine N-oxides useful as HIV reverse transcriptase inhibitors
US7932272B2 (en) 2003-09-30 2011-04-26 Eisai R&D Management Co., Ltd. Antifungal agent containing heterocyclic compound
JP4874958B2 (en) 2005-03-30 2012-02-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 Antifungal agents containing pyridine derivatives
TWI385169B (en) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd Heterocyclic substituted pyridine derivatives and antifungal agent containing same
US8183264B2 (en) 2006-09-21 2012-05-22 Eisai R&D Managment Co., Ltd. Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
CN102702185A (en) 2007-04-27 2012-10-03 卫材R&D管理有限公司 Heterocycle-substituted pyridine derivative's salt or crystal thereof
US8513287B2 (en) 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US8188119B2 (en) 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
EA019511B1 (en) 2009-05-28 2014-04-30 Новартис Аг Substituted aminopropionic derivatives as neprilysin inhibitors
MA33364B1 (en) 2009-05-28 2012-06-01 Novartis Ag SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors
SI2956464T1 (en) 2013-02-14 2018-08-31 Novartis Ag Substituted bisphenyl butanoic phosphonic acid derivatives as nep (neutral endopeptidase) inhibitors
JP6301371B2 (en) 2013-02-14 2018-04-11 ノバルティス アーゲー Substituted bisphenylbutanoic acid derivatives as NEP inhibitors with improved in vivo efficacy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE113036T1 (en) * 1988-08-04 1994-11-15 Hoechst Ag IMPROVED PROCESS FOR THE PRODUCTION OF N,N-BIS(ALKOXYALKYL)-PYRIDINE-2,4-DICARBONIC DIAMIDES.
DE3933802A1 (en) * 1989-10-10 1991-04-18 Basf Ag Pyridine derivatives and their use to combat unwanted plant growth
ZA91291B (en) * 1990-01-16 1991-09-25 Hoechst Ag Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof
DE4032147A1 (en) * 1990-10-10 1992-04-16 Bayer Ag USE OF SUBSTITUTED 2-MERCAPTONICOTINSAEUREDERIVATES FOR THE CAPACITY OF ENDOPARASITES, NEW SUBSTITUTED 2-MERCAPTONICOTINSAEUREDERIVATES AND METHOD FOR THE PRODUCTION THEREOF

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103037693A (en) * 2010-05-24 2013-04-10 范德比尔特大学 Substituted-6-methylnicotinamides as MGLUR5 positive allosteric modulators

Also Published As

Publication number Publication date
CA2078590A1 (en) 1993-03-20
FI924164A0 (en) 1992-09-17
JPH05213883A (en) 1993-08-24
FI924164A (en) 1993-03-20
NO923638L (en) 1993-03-22
EP0533130A1 (en) 1993-03-24
NO923638D0 (en) 1992-09-18
IL103206A0 (en) 1993-02-21

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