AU2380800A - Structural basis for pterin function in nitric oxide synthase - Google Patents

Structural basis for pterin function in nitric oxide synthase

Info

Publication number
AU2380800A
AU2380800A AU23808/00A AU2380800A AU2380800A AU 2380800 A AU2380800 A AU 2380800A AU 23808/00 A AU23808/00 A AU 23808/00A AU 2380800 A AU2380800 A AU 2380800A AU 2380800 A AU2380800 A AU 2380800A
Authority
AU
Australia
Prior art keywords
pterin
function
nitric oxide
oxide synthase
structural basis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU23808/00A
Inventor
Vladimir Kral
Pavel Martasek
Bettie Sue S. Masters
Thomas L. Poulos
C. S. Raman
Linda J. Roman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System filed Critical University of Texas System
Publication of AU2380800A publication Critical patent/AU2380800A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0073—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
    • C12N9/0075—Nitric-oxide synthase (1.14.13.39)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
AU23808/00A 1998-12-22 1999-12-22 Structural basis for pterin function in nitric oxide synthase Abandoned AU2380800A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11320498P 1998-12-22 1998-12-22
US60113204 1998-12-22
PCT/US1999/030707 WO2000037653A1 (en) 1998-12-22 1999-12-22 Structural basis for pterin function in nitric oxide synthase

Publications (1)

Publication Number Publication Date
AU2380800A true AU2380800A (en) 2000-07-12

Family

ID=22348141

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23808/00A Abandoned AU2380800A (en) 1998-12-22 1999-12-22 Structural basis for pterin function in nitric oxide synthase

Country Status (4)

Country Link
EP (1) EP1141320A1 (en)
AU (1) AU2380800A (en)
CA (1) CA2361196A1 (en)
WO (1) WO2000037653A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004291082A1 (en) * 2003-11-13 2005-06-02 The General Hospital Corporation Methods for treating pain
PT1708690T (en) 2003-11-17 2016-09-19 Biomarin Pharm Inc Treatment of phenylketonuria with bh4
US9216178B2 (en) 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018156A1 (en) * 1992-03-05 1993-09-16 The General Hospital Corporation Endothelial nitric oxide synthase
US5498539A (en) * 1992-07-02 1996-03-12 Daiichi Pharmaceutical Co., Ltd. Bovine endothelial nitric oxide synthase nucleic acids
US5744340A (en) * 1995-06-09 1998-04-28 Schering Corporation Expression of human inducible nitric oxide synthase
US5919682A (en) * 1995-08-24 1999-07-06 Board Of Regents, University Of Texas System Overproduction of neuronal nitric oxide synthase
US6150500A (en) * 1996-07-12 2000-11-21 Salerno; John C. Activators of endothelial nitric oxide synthase

Also Published As

Publication number Publication date
WO2000037653A1 (en) 2000-06-29
EP1141320A1 (en) 2001-10-10
CA2361196A1 (en) 2000-06-29

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase