AU2355895A - Mac-1 i-domain protein useful in blocking adhesion and migration of neutrophils - Google Patents

Mac-1 i-domain protein useful in blocking adhesion and migration of neutrophils

Info

Publication number
AU2355895A
AU2355895A AU23558/95A AU2355895A AU2355895A AU 2355895 A AU2355895 A AU 2355895A AU 23558/95 A AU23558/95 A AU 23558/95A AU 2355895 A AU2355895 A AU 2355895A AU 2355895 A AU2355895 A AU 2355895A
Authority
AU
Australia
Prior art keywords
neutrophils
mac
migration
domain protein
protein useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU23558/95A
Inventor
Donald C. Anderson
Mary L Bajt-Jaeschke
Michael B Fairbanks
Robert L Heinrikson
Che-Shen C. Tomich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU2355895A publication Critical patent/AU2355895A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70553—Integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU23558/95A 1994-04-26 1995-04-19 Mac-1 i-domain protein useful in blocking adhesion and migration of neutrophils Abandoned AU2355895A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US233596 1988-08-18
US23359694A 1994-04-26 1994-04-26
PCT/US1995/004439 WO1995029243A1 (en) 1994-04-26 1995-04-19 Mac-1 i-domain protein useful in blocking adhesion and migration of neutrophils

Publications (1)

Publication Number Publication Date
AU2355895A true AU2355895A (en) 1995-11-16

Family

ID=22877913

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23558/95A Abandoned AU2355895A (en) 1994-04-26 1995-04-19 Mac-1 i-domain protein useful in blocking adhesion and migration of neutrophils

Country Status (4)

Country Link
EP (1) EP0758393A1 (en)
JP (1) JPH09512426A (en)
AU (1) AU2355895A (en)
WO (1) WO1995029243A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU710612B2 (en) * 1995-12-13 1999-09-23 Abbvie Inc. Endothelial cell proliferation inhibitor and method of use
JP4426650B2 (en) * 1996-05-03 2010-03-03 アボット・ラボラトリーズ Novel anti-angiogenic peptide, polynucleotide encoding it, and method for inhibiting angiogenesis
WO1999006545A2 (en) * 1997-08-01 1999-02-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Composition and method for the detection of diseases associated with amyloid-like fibril or protein aggregate formation
EP1005654B1 (en) 1997-08-01 2006-04-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Novel method of detecting amyloid-like fibrils or protein aggregates
JP2003527439A (en) 2000-03-17 2003-09-16 ミレニアム・ファーマシューティカルズ・インコーポレイテッド Method for suppressing stenosis and restenosis using a mixture of anti-CD18 antibody and anti-CCR2 antibody
AU2013248972A1 (en) 2012-04-20 2014-11-13 Adhaere Pharmaceuticals, Inc. Compounds and methods for regulating integrins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0364690A3 (en) * 1988-08-23 1990-07-18 Dana Farber Cancer Institute The alpha-subunit of the mac-1 leukocyte adhesion receptor

Also Published As

Publication number Publication date
WO1995029243A1 (en) 1995-11-02
JPH09512426A (en) 1997-12-16
EP0758393A1 (en) 1997-02-19

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