AU2298301A - Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators - Google Patents

Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators

Info

Publication number
AU2298301A
AU2298301A AU22983/01A AU2298301A AU2298301A AU 2298301 A AU2298301 A AU 2298301A AU 22983/01 A AU22983/01 A AU 22983/01A AU 2298301 A AU2298301 A AU 2298301A AU 2298301 A AU2298301 A AU 2298301A
Authority
AU
Australia
Prior art keywords
inhibitors
flavones
cyclooxygenase
nitric oxide
potassium channel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU22983/01A
Inventor
Yang Ling Ling Chen
Tony Jer-Fu Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Southern Illinois University System
Original Assignee
Southern Illinois University System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Illinois University System filed Critical Southern Illinois University System
Publication of AU2298301A publication Critical patent/AU2298301A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
AU22983/01A 1999-10-20 2000-10-20 Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators Abandoned AU2298301A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16061299P 1999-10-20 1999-10-20
US60160612 1999-10-20
PCT/US2000/041396 WO2001030342A1 (en) 1999-10-20 2000-10-20 Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators

Publications (1)

Publication Number Publication Date
AU2298301A true AU2298301A (en) 2001-05-08

Family

ID=22577612

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22983/01A Abandoned AU2298301A (en) 1999-10-20 2000-10-20 Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators

Country Status (2)

Country Link
AU (1) AU2298301A (en)
WO (1) WO2001030342A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA80682C2 (en) * 2001-08-06 2007-10-25 Pharmacia Corp Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
DE10139793A1 (en) * 2001-08-14 2003-02-27 Beiersdorf Ag Use of wogonin for the production of cosmetic or dermatological preparations for the prophylaxis and treatment of inflammatory skin conditions and / or for skin protection in the case of sensitive, dry skin
DE10139791A1 (en) * 2001-08-14 2003-02-27 Beiersdorf Ag Use of Oroxylin A for the production of cosmetic or dermatological preparations for the prophylaxis and treatment of inflammatory skin conditions and / or for skin protection in the case of sensitive, dry skin
DE60313754T2 (en) * 2002-03-06 2008-01-24 The Medical Research and Education Trust, San Diego BOTANICAL EXTRACT WITH ANTICIPATIVE ACTIVITY INCLUDING ISOLIQUIRITIGENIN
EP1808172A3 (en) * 2002-03-06 2010-05-26 Activephyto Technologies Limited Botanical extract compositions and methods of use
US6884783B2 (en) 2002-05-03 2005-04-26 Unigen Pharmaceuticals, Inc. 7-Hydroxy chromones as potent antioxidants
US6740677B2 (en) * 2002-08-19 2004-05-25 Hong Xue Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2′ hydroxyflavonoids
CN1674889A (en) * 2002-08-19 2005-09-28 华晶基因技术有限公司 Methods of predicting GABAa receptor efficacies for flavonoid compounds and uses therefor
CA2502975A1 (en) * 2002-10-22 2004-05-06 Jenken Biosciences, Inc. Chromones and chromone derivatives and uses thereof
KR100609007B1 (en) * 2003-12-09 2006-08-09 한국화학연구원 Chrysin derivaties for inhibitiing selectively cox-2 enzyme
TWI454261B (en) 2007-01-09 2014-10-01 Unigen Inc Chromones as therapeutic agents
CN105078957B (en) * 2014-05-04 2017-11-21 中国医学科学院基础医学研究所 Trihydroxyflavone is preparing the purposes in being used to treat or prevent the medicine of abdominal aneurvsm
CN107556278A (en) * 2017-09-08 2018-01-09 湖北中医药大学 A kind of the flavanone alcohols compound and its preparation method and purposes of fluorine substitution
CN113750085B (en) * 2020-06-02 2023-08-29 中国科学院上海药物研究所 Use of natural compounds and derivatives thereof for the treatment of arterial lesions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8588398A (en) * 1997-07-25 1999-02-16 Duke University Composition for protection from damage by ischemia

Also Published As

Publication number Publication date
WO2001030342A9 (en) 2001-10-18
WO2001030342A1 (en) 2001-05-03

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase