AU2237095A - Method for delivering biologically active materials using a thioester or thioether prodrug - Google Patents

Method for delivering biologically active materials using a thioester or thioether prodrug

Info

Publication number
AU2237095A
AU2237095A AU22370/95A AU2237095A AU2237095A AU 2237095 A AU2237095 A AU 2237095A AU 22370/95 A AU22370/95 A AU 22370/95A AU 2237095 A AU2237095 A AU 2237095A AU 2237095 A AU2237095 A AU 2237095A
Authority
AU
Australia
Prior art keywords
thioester
thioether
prodrug
biologically active
active materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU22370/95A
Inventor
Stephen J. Galli
Maureen H McAloon
Richard J Sharpe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arcturus Pharmaceutical Corp
Original Assignee
Arcturus Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arcturus Pharmaceutical Corp filed Critical Arcturus Pharmaceutical Corp
Publication of AU2237095A publication Critical patent/AU2237095A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU22370/95A 1994-04-01 1995-04-03 Method for delivering biologically active materials using a thioester or thioether prodrug Abandoned AU2237095A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22185694A 1994-04-01 1994-04-01
US221856 1994-04-01
PCT/US1995/004084 WO1995026719A1 (en) 1994-04-01 1995-04-03 Method for delivering biologically active materials using a thioester or thioether prodrug

Publications (1)

Publication Number Publication Date
AU2237095A true AU2237095A (en) 1995-10-23

Family

ID=22829688

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22370/95A Abandoned AU2237095A (en) 1994-04-01 1995-04-03 Method for delivering biologically active materials using a thioester or thioether prodrug

Country Status (2)

Country Link
AU (1) AU2237095A (en)
WO (1) WO1995026719A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2277011A1 (en) * 1997-01-13 1998-07-16 Universite Laval Membrane-permeable derivatives converted intracellularly into active peptides
CN1261803A (en) 1997-07-01 2000-08-02 埃瑟若詹尼克斯公司 Antioxidant enhancement of therapy for hyperproliferative conditions
GB9811692D0 (en) * 1998-06-01 1998-07-29 Medical Res Council Improvements in or relating to uptake of substances by cells
US6416737B1 (en) 1998-11-19 2002-07-09 Board Of Trustees Of The University Of Arkansas Increasing bone strength with selected bisphosphonates
JP5201546B2 (en) * 2008-01-18 2013-06-05 学校法人近畿大学 N-acetylcysteine-conjugated bile acid, pharmaceutical composition containing the same and method for producing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS171787B1 (en) * 1973-11-09 1976-11-29
US4286964A (en) * 1979-10-12 1981-09-01 Seed Brian S Polyfunctional epoxides and halohydrins used as bridging groups to bind aromatic amine group-containing alcohols and thiols to hydroxyl bearing substrates

Also Published As

Publication number Publication date
WO1995026719A1 (en) 1995-10-12

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