AU2206701A - A reversible linkage technology for controlled conjugation - Google Patents

A reversible linkage technology for controlled conjugation

Info

Publication number
AU2206701A
AU2206701A AU22067/01A AU2206701A AU2206701A AU 2206701 A AU2206701 A AU 2206701A AU 22067/01 A AU22067/01 A AU 22067/01A AU 2206701 A AU2206701 A AU 2206701A AU 2206701 A AU2206701 A AU 2206701A
Authority
AU
Australia
Prior art keywords
reversible linkage
linkage technology
controlled conjugation
conjugation
controlled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU22067/01A
Inventor
Nicholas Flinn
Tony Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Sanofi Pasteur Holding Ltd
Original Assignee
SmithKline Beecham Biologicals SA
Acambis Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9930233.3A external-priority patent/GB9930233D0/en
Priority claimed from GB0004096A external-priority patent/GB0004096D0/en
Priority claimed from GB0020708A external-priority patent/GB0020708D0/en
Priority claimed from GB0020707A external-priority patent/GB0020707D0/en
Application filed by SmithKline Beecham Biologicals SA, Acambis Research Ltd filed Critical SmithKline Beecham Biologicals SA
Publication of AU2206701A publication Critical patent/AU2206701A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AU22067/01A 1999-12-21 2000-12-21 A reversible linkage technology for controlled conjugation Abandoned AU2206701A (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GBGB9930233.3A GB9930233D0 (en) 1999-12-21 1999-12-21 A reversible linkage technology for controlled conjugation
GB9930233 1999-12-21
GB0004096A GB0004096D0 (en) 2000-02-22 2000-02-22 A reversible linkage technology for controlled conjugation
GB0004096 2000-02-22
GB0020708A GB0020708D0 (en) 2000-08-22 2000-08-22 A reversible linkage technology for controlled conjugation
GB0020708 2000-08-22
GB0020707A GB0020707D0 (en) 2000-08-22 2000-08-22 A reversible linkage technology for controlled conjugation
GB0020707 2000-08-22
PCT/GB2000/004935 WO2001045745A2 (en) 1999-12-21 2000-12-21 A reversible linkage technology for controlled conjugation

Publications (1)

Publication Number Publication Date
AU2206701A true AU2206701A (en) 2001-07-03

Family

ID=27447796

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22067/01A Abandoned AU2206701A (en) 1999-12-21 2000-12-21 A reversible linkage technology for controlled conjugation

Country Status (2)

Country Link
AU (1) AU2206701A (en)
WO (1) WO2001045745A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050007454A (en) * 2002-04-08 2005-01-18 아무라 테라피틱스 리미티드 Organic molecules
WO2020113094A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4033714C3 (en) * 1990-10-24 1995-09-07 Brahms Diagnostica Gmbh New hapten analysis based on the principle of an antigen-antibody reaction
JPH072895A (en) * 1993-04-28 1995-01-06 Eli Lilly & Co Antibody - drug conjugate
US6001364A (en) * 1993-05-05 1999-12-14 Gryphon Sciences Hetero-polyoxime compounds and their preparation by parallel assembly
WO1995003321A1 (en) * 1993-07-20 1995-02-02 Bionebraska, Inc. Method for endomodification of proteins
WO1997024459A1 (en) * 1995-12-29 1997-07-10 Phanos Technologoes, Inc. Method for reducing unwanted cellular adhesions
GB9621985D0 (en) * 1996-10-22 1996-12-18 Peptide Therapeutics Ltd A solid-phase technology for the preparation of libraries of bi-directally functionalised drug-like molecules
MXPA01008612A (en) * 1999-02-25 2003-06-24 Smithkline Beecham Biolog Epitopes or mimotopes derived from the c-epsilon-3 or c-epsilon-4 domains of ige, antagonists thereof, and their therapeutic uses.

Also Published As

Publication number Publication date
WO2001045745A3 (en) 2002-05-10
WO2001045745A2 (en) 2001-06-28

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase