AU2186497A - Milk of transgenic animals containing human alpha1-antitrypsin and use of human alpha1-antitrypsin to treat bile acid related diseases - Google Patents

Milk of transgenic animals containing human alpha1-antitrypsin and use of human alpha1-antitrypsin to treat bile acid related diseases

Info

Publication number
AU2186497A
AU2186497A AU21864/97A AU2186497A AU2186497A AU 2186497 A AU2186497 A AU 2186497A AU 21864/97 A AU21864/97 A AU 21864/97A AU 2186497 A AU2186497 A AU 2186497A AU 2186497 A AU2186497 A AU 2186497A
Authority
AU
Australia
Prior art keywords
antitrypsin
human alpha1
milk
related diseases
transgenic animals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU21864/97A
Inventor
Joyce Carlson
Sabina-Marija Janciauskiene
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JANCIAUSKIENE SABINA MARIJA
Original Assignee
JANCIAUSKIENE SABINA MARIJA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JANCIAUSKIENE SABINA MARIJA filed Critical JANCIAUSKIENE SABINA MARIJA
Publication of AU2186497A publication Critical patent/AU2186497A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
AU21864/97A 1996-03-21 1997-03-20 Milk of transgenic animals containing human alpha1-antitrypsin and use of human alpha1-antitrypsin to treat bile acid related diseases Abandoned AU2186497A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9601091A SE9601091L (en) 1996-03-21 1996-03-21 Use of a protein substance for the binding of steroid-like molecules
SE9601091 1996-03-21
PCT/SE1997/000465 WO1997034628A1 (en) 1996-03-21 1997-03-20 Milk of transgenic animals containing human alpha1-antitrypsin and use of human alpha1-antitrypsin to treat bile acid related diseases

Publications (1)

Publication Number Publication Date
AU2186497A true AU2186497A (en) 1997-10-10

Family

ID=20401887

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21864/97A Abandoned AU2186497A (en) 1996-03-21 1997-03-20 Milk of transgenic animals containing human alpha1-antitrypsin and use of human alpha1-antitrypsin to treat bile acid related diseases

Country Status (4)

Country Link
EP (1) EP0904102A1 (en)
AU (1) AU2186497A (en)
SE (1) SE9601091L (en)
WO (1) WO1997034628A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69940700D1 (en) * 1998-11-19 2009-05-20 Pharming Intellectual Pty Bv STABILIZATION OF MILK TRANSGENER PETS
US7030289B2 (en) 1998-11-19 2006-04-18 Ppl Therapeutics (Scotland) Ltd Stabilization of milk from transgenic animals
WO2000044390A1 (en) * 1999-02-01 2000-08-03 John Lezdey Treatment of bladder and gastrointestinal mastocytosis
AUPP971399A0 (en) * 1999-04-12 1999-05-06 Life Therapeutics Limited Separation of plasma components
JPWO2009008120A1 (en) * 2007-07-12 2010-09-02 杉山　雄一 Membrane protein stabilizer and stabilization method
CN108697704A (en) 2016-02-22 2018-10-23 诺华股份有限公司 Use the method for FXR agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873316A (en) * 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
US5439824A (en) * 1993-05-06 1995-08-08 The United States Of America Increased expression of α-1-antitrypsin in expression vectors through the inclusion of intron II

Also Published As

Publication number Publication date
EP0904102A1 (en) 1999-03-31
WO1997034628A1 (en) 1997-09-25
SE9601091D0 (en) 1996-03-21
SE9601091L (en) 1997-09-22

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