AU2142588A - Pharmaceutical structure - Google Patents

Pharmaceutical structure

Info

Publication number
AU2142588A
AU2142588A AU21425/88A AU2142588A AU2142588A AU 2142588 A AU2142588 A AU 2142588A AU 21425/88 A AU21425/88 A AU 21425/88A AU 2142588 A AU2142588 A AU 2142588A AU 2142588 A AU2142588 A AU 2142588A
Authority
AU
Australia
Prior art keywords
protein
haptens
immunogenic
pharmaceutical structure
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU21425/88A
Other versions
AU627154B2 (en
Inventor
Paul Messner
Wolfgang Mundt
Uwe B. Sleytr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2142588A publication Critical patent/AU2142588A/en
Application granted granted Critical
Publication of AU627154B2 publication Critical patent/AU627154B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

In the pharmaceutical structure haptens and/or immunogenic or immunostimulant substances are bound to a protein carrier. In order to obtain accurately definable binding sites of the haptens and/or immunogenic or immunostimulant substances on the protein carrier, the latter is formed by protein molecules or protein-containing molecules which are, where appropriate, covalently crosslinked with one another and arranged in a crystalline or paracrystalline manner. <IMAGE>
AU21425/88A 1987-08-21 1988-08-19 Pharmaceutical structure Ceased AU627154B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3727987 1987-08-21
DE19873727987 DE3727987A1 (en) 1987-08-21 1987-08-21 PHARMACEUTICAL STRUCTURE

Publications (2)

Publication Number Publication Date
AU2142588A true AU2142588A (en) 1989-03-16
AU627154B2 AU627154B2 (en) 1992-08-20

Family

ID=6334228

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21425/88A Ceased AU627154B2 (en) 1987-08-21 1988-08-19 Pharmaceutical structure

Country Status (7)

Country Link
EP (1) EP0306473B1 (en)
JP (1) JP2708487B2 (en)
AT (1) ATE97323T1 (en)
AU (1) AU627154B2 (en)
DE (2) DE3727987A1 (en)
ES (1) ES2061734T3 (en)
IL (1) IL87390A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7249491A (en) * 1990-03-02 1991-09-18 Alberta Research Council Inc. Improved immunogenic compositions
DE4115038A1 (en) * 1991-05-08 1992-11-12 Genentech Inc NEW CONJUGATES, COMPOSED OF A GLYCOPROTEIN AND A NUCLEIC ACID-BINDING SUBSTANCE
US20080254058A1 (en) * 2004-12-14 2008-10-16 Alk-Abello A/S Pharmaceutical Composition Comprising a Bacterial Cell Displaying a Heterologous Proteinaceous Compound
ES2383857B1 (en) 2010-11-23 2013-05-13 Consejo Superior De Investigaciones Científicas (Csic) HAPTENS AND IMMUNOREACTIVE AND ITS USE IN THE OBTAINING OF FAMILY ANTIBODIES AND IMMUNO TESTS FOR QUINOLONES

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6789910D0 (en) * 1966-10-17 1973-05-17 Fmc Corp PROCESS TO PREPARE EDIBLE CONTAINING MICRO CRYSTALLINE COLLAGEN
US4166767A (en) * 1976-03-25 1979-09-04 Dainippon Pharmaceutical Co., Ltd. Insolubilized antibody
DE2636206C3 (en) * 1976-08-12 1981-06-04 C.H. Boehringer Sohn, 6507 Ingelheim Carrier-fixed enzymes and their manufacture and use
JPS5428813A (en) * 1977-08-09 1979-03-03 Yuuichi Yamamura Solid preparation containing cell membrane extract substance used as suspension when using same
US4411832A (en) * 1979-11-26 1983-10-25 Pedro Cuatrecasas Polysaccharide matrices comprising macromolecular spacer arms for use as adsorbents in affinity chromatography techniques
DE3167679D1 (en) * 1980-03-31 1985-01-24 Inst Int Pathologie Cellulaire Pharmaceutical forms, their preparation and compositions containing the same
US4465668A (en) * 1981-02-27 1984-08-14 Asahi Kasei Kogyo Kabushiki Kaisha Method for improving intestinal absorption of cephalosporin derivatives
DE3224788A1 (en) * 1981-07-17 1983-02-03 South African Inventions Development Corp., Scientia, Pretoria,Transvaal CARRIER-TIED IMMUNOGENIC MATERIAL
AT373278B (en) * 1982-03-23 1984-01-10 Inst Po Mikrobiologia METHOD FOR IMMOBILIZING MICROBIC CELLS WITH A GLUCOSE ISOMERASE ACTIVITY
US4604376A (en) * 1982-04-21 1986-08-05 Research Corporation Enteric compounds and complexes
US4663160A (en) * 1983-03-14 1987-05-05 Miles Laboratories, Inc. Vaccines for gram-negative bacteria
US4486344A (en) * 1983-03-28 1984-12-04 Miles Laboratories, Inc. Urea-linked immunogens, antibodies, and preparative method
SE8405493D0 (en) * 1984-11-01 1984-11-01 Bror Morein IMMUNOGENT COMPLEX AND KITCHEN FOR PREPARING IT AND USING IT AS IMMUNOSTIMENTING AGENTS
CA1267087A (en) * 1985-02-14 1990-03-27 Nicolaas Visser Synthetic immunogen

Also Published As

Publication number Publication date
IL87390A0 (en) 1989-01-31
ES2061734T3 (en) 1994-12-16
EP0306473B1 (en) 1993-11-18
EP0306473A1 (en) 1989-03-08
JP2708487B2 (en) 1998-02-04
ATE97323T1 (en) 1993-12-15
AU627154B2 (en) 1992-08-20
IL87390A (en) 1993-07-08
DE3727987A1 (en) 1989-03-02
DE3885680D1 (en) 1993-12-23
JPH01207245A (en) 1989-08-21

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