AU2023257191A1 - Cxcr4-targeting compounds, and methods of making and using the same - Google Patents
Cxcr4-targeting compounds, and methods of making and using the same Download PDFInfo
- Publication number
- AU2023257191A1 AU2023257191A1 AU2023257191A AU2023257191A AU2023257191A1 AU 2023257191 A1 AU2023257191 A1 AU 2023257191A1 AU 2023257191 A AU2023257191 A AU 2023257191A AU 2023257191 A AU2023257191 A AU 2023257191A AU 2023257191 A1 AU2023257191 A1 AU 2023257191A1
- Authority
- AU
- Australia
- Prior art keywords
- residue
- compound
- lys
- independently
- forms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/13—Labelling of peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263332885P | 2022-04-20 | 2022-04-20 | |
| US63/332,885 | 2022-04-20 | ||
| PCT/CA2023/050538 WO2023201435A1 (en) | 2022-04-20 | 2023-04-20 | Cxcr4-targeting compounds, and methods of making and using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2023257191A1 true AU2023257191A1 (en) | 2024-10-10 |
Family
ID=88418769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2023257191A Pending AU2023257191A1 (en) | 2022-04-20 | 2023-04-20 | Cxcr4-targeting compounds, and methods of making and using the same |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250242064A1 (https=) |
| EP (1) | EP4511384A1 (https=) |
| JP (1) | JP2025513489A (https=) |
| CN (1) | CN119325480A (https=) |
| AU (1) | AU2023257191A1 (https=) |
| CA (1) | CA3249424A1 (https=) |
| WO (1) | WO2023201435A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025218761A1 (zh) * | 2024-04-17 | 2025-10-23 | 晶核生物医药科技(上海)有限公司 | 环状肽类化合物、其药物组合物及其应用 |
| CN120137854B (zh) * | 2025-05-13 | 2025-09-23 | 中国农业大学 | 一种具有广泛pH适应性的有机磷矿化复合菌群及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2377579A1 (en) * | 2007-05-30 | 2011-10-19 | Eli Lilly and Company | Cyclic peptide CXCR4 antagonists |
| KR20230145543A (ko) * | 2017-09-05 | 2023-10-17 | 메인라인 바이오사이언스 | 고친화성 cxcr4 선택적 결합 콘쥬게이트 및 그 사용 방법 |
| JP2021165234A (ja) * | 2018-07-03 | 2021-10-14 | 富士フイルム富山化学株式会社 | Ｃｘｃｒ４結合性化合物もしくはその塩またはそれらと金属との錯体 |
| US20220218852A1 (en) * | 2019-04-18 | 2022-07-14 | Provincial Health Services Authority | Novel radiolabelled cxcr4-targeting compounds for diagnosis and therapy |
| JP2023549469A (ja) * | 2020-10-21 | 2023-11-27 | プロビンシャル・ヘルス・サービシーズ・オーソリティ | 新規ｃｘｃｒ４標的化合物 |
-
2023
- 2023-04-20 EP EP23790818.1A patent/EP4511384A1/en active Pending
- 2023-04-20 AU AU2023257191A patent/AU2023257191A1/en active Pending
- 2023-04-20 JP JP2024562169A patent/JP2025513489A/ja active Pending
- 2023-04-20 CA CA3249424A patent/CA3249424A1/en active Pending
- 2023-04-20 CN CN202380039010.3A patent/CN119325480A/zh active Pending
- 2023-04-20 US US18/855,675 patent/US20250242064A1/en active Pending
- 2023-04-20 WO PCT/CA2023/050538 patent/WO2023201435A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN119325480A (zh) | 2025-01-17 |
| JP2025513489A (ja) | 2025-04-24 |
| EP4511384A1 (en) | 2025-02-26 |
| WO2023201435A1 (en) | 2023-10-26 |
| CA3249424A1 (en) | 2023-10-26 |
| WO2023201435A8 (en) | 2023-12-28 |
| US20250242064A1 (en) | 2025-07-31 |
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