AU2022426492A1 - Respiratory stimulant parenteral formulations - Google Patents

Respiratory stimulant parenteral formulations Download PDF

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Publication number
AU2022426492A1
AU2022426492A1 AU2022426492A AU2022426492A AU2022426492A1 AU 2022426492 A1 AU2022426492 A1 AU 2022426492A1 AU 2022426492 A AU2022426492 A AU 2022426492A AU 2022426492 A AU2022426492 A AU 2022426492A AU 2022426492 A1 AU2022426492 A1 AU 2022426492A1
Authority
AU
Australia
Prior art keywords
formulation
substituted
compound
parenteral
storage conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2022426492A
Other languages
English (en)
Inventor
Isaac AGYEMANG
Jiayi Chen
Frank Diana
Devon E. DODD
Joseph V. PERGOLIZZI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enalare Therapeutics Inc
Original Assignee
Enalare Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enalare Therapeutics Inc filed Critical Enalare Therapeutics Inc
Publication of AU2022426492A1 publication Critical patent/AU2022426492A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AU2022426492A 2021-12-27 2022-12-23 Respiratory stimulant parenteral formulations Pending AU2022426492A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163293985P 2021-12-27 2021-12-27
US63/293,985 2021-12-27
US202263313472P 2022-02-24 2022-02-24
US63/313,472 2022-02-24
PCT/US2022/053935 WO2023129502A1 (en) 2021-12-27 2022-12-23 Respiratory stimulant parenteral formulations

Publications (1)

Publication Number Publication Date
AU2022426492A1 true AU2022426492A1 (en) 2024-07-18

Family

ID=86992921

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2022426492A Pending AU2022426492A1 (en) 2021-12-27 2022-12-23 Respiratory stimulant parenteral formulations

Country Status (9)

Country Link
US (1) US20230210857A1 (https=)
EP (1) EP4456900A4 (https=)
JP (1) JP2025501169A (https=)
KR (1) KR20240150426A (https=)
AU (1) AU2022426492A1 (https=)
CA (1) CA3242509A1 (https=)
MX (1) MX2024008162A (https=)
TW (1) TW202333732A (https=)
WO (1) WO2023129502A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230414624A1 (en) * 2022-06-24 2023-12-28 Enalare Therapeutics Inc. Methods of treating neurological ventilatory insufficiency

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199901968T2 (xx) * 1996-12-24 1999-12-21 Biogen, Inc. Sabit s�v� interferon form�lleri.
US20120295911A1 (en) * 2010-11-29 2012-11-22 Galleon Pharmaceuticals, Inc. Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases
AU2011336764B2 (en) * 2010-11-29 2017-02-23 Galleon Pharmaceuticals, Inc. Novel compounds as respiratory stimulants for treatment of breathing control disorders or diseases
DK2701684T3 (en) * 2011-04-28 2017-09-18 Platform Brightworks Two Ltd Improved parenteral formulations of lipophilic pharmaceuticals and methods for their preparation and use
SG11201503505QA (en) * 2012-11-15 2015-06-29 Galleon Pharmaceuticals Inc Novel orally bioavailable breathing control modulating compounds, and methods of using same
GB201502412D0 (en) * 2015-02-13 2015-04-01 Canbex Therapeutics Ltd Therapeutic use

Also Published As

Publication number Publication date
KR20240150426A (ko) 2024-10-15
CA3242509A1 (en) 2023-07-06
EP4456900A1 (en) 2024-11-06
WO2023129502A1 (en) 2023-07-06
MX2024008162A (es) 2024-09-17
TW202333732A (zh) 2023-09-01
JP2025501169A (ja) 2025-01-17
US20230210857A1 (en) 2023-07-06
EP4456900A4 (en) 2025-12-24

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