AU2022358311A1 - Cochlea injection devices, systems, and methods for otology - Google Patents
Cochlea injection devices, systems, and methods for otology Download PDFInfo
- Publication number
- AU2022358311A1 AU2022358311A1 AU2022358311A AU2022358311A AU2022358311A1 AU 2022358311 A1 AU2022358311 A1 AU 2022358311A1 AU 2022358311 A AU2022358311 A AU 2022358311A AU 2022358311 A AU2022358311 A AU 2022358311A AU 2022358311 A1 AU2022358311 A1 AU 2022358311A1
- Authority
- AU
- Australia
- Prior art keywords
- micro
- cannula
- guidewire
- cochlea
- scala tympani
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 102
- 210000003477 cochlea Anatomy 0.000 title claims description 121
- 238000002347 injection Methods 0.000 title claims description 6
- 239000007924 injection Substances 0.000 title claims description 6
- 210000001079 scala tympani Anatomy 0.000 claims description 81
- 239000003814 drug Substances 0.000 claims description 61
- 229940124597 therapeutic agent Drugs 0.000 claims description 61
- 239000012528 membrane Substances 0.000 claims description 46
- 239000012530 fluid Substances 0.000 claims description 41
- 210000000959 ear middle Anatomy 0.000 claims description 21
- 210000003454 tympanic membrane Anatomy 0.000 claims description 18
- 238000012384 transportation and delivery Methods 0.000 claims description 13
- 210000000883 ear external Anatomy 0.000 claims description 7
- 238000012800 visualization Methods 0.000 claims description 6
- 230000004044 response Effects 0.000 claims description 4
- 238000004891 communication Methods 0.000 claims description 2
- 210000003027 ear inner Anatomy 0.000 abstract description 17
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 7
- 206010011878 Deafness Diseases 0.000 abstract description 4
- 208000016354 hearing loss disease Diseases 0.000 abstract description 4
- 238000002560 therapeutic procedure Methods 0.000 abstract description 4
- 231100000888 hearing loss Toxicity 0.000 abstract description 3
- 230000010370 hearing loss Effects 0.000 abstract description 3
- 208000032625 disorder of ear Diseases 0.000 abstract description 2
- 238000001802 infusion Methods 0.000 description 23
- 239000013598 vector Substances 0.000 description 12
- 206010011891 Deafness neurosensory Diseases 0.000 description 9
- 208000009966 Sensorineural Hearing Loss Diseases 0.000 description 9
- 239000003795 chemical substances by application Substances 0.000 description 9
- 231100000879 sensorineural hearing loss Toxicity 0.000 description 9
- 208000023573 sensorineural hearing loss disease Diseases 0.000 description 9
- 238000013459 approach Methods 0.000 description 7
- 230000001225 therapeutic effect Effects 0.000 description 6
- 208000027601 Inner ear disease Diseases 0.000 description 4
- 238000009792 diffusion process Methods 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000027530 Meniere disease Diseases 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 210000000417 chorda tympani nerve Anatomy 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 238000001415 gene therapy Methods 0.000 description 3
- 239000007943 implant Substances 0.000 description 3
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 3
- 229910001000 nickel titanium Inorganic materials 0.000 description 3
- 230000037361 pathway Effects 0.000 description 3
- 210000004049 perilymph Anatomy 0.000 description 3
- 150000003384 small molecules Chemical class 0.000 description 3
- 230000006641 stabilisation Effects 0.000 description 3
- 238000011105 stabilization Methods 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 206010008642 Cholesteatoma Diseases 0.000 description 2
- 206010033078 Otitis media Diseases 0.000 description 2
- 206010033109 Ototoxicity Diseases 0.000 description 2
- 210000003484 anatomy Anatomy 0.000 description 2
- 239000000090 biomarker Substances 0.000 description 2
- 238000009530 blood pressure measurement Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 238000002405 diagnostic procedure Methods 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 238000012377 drug delivery Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000002388 eustachian tube Anatomy 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000007726 management method Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 231100000262 ototoxicity Toxicity 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 208000012639 Balance disease Diseases 0.000 description 1
- 206010016717 Fistula Diseases 0.000 description 1
- 229910052688 Gadolinium Inorganic materials 0.000 description 1
- 206010019196 Head injury Diseases 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 206010023567 Labyrinthitis Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 239000004696 Poly ether ether ketone Substances 0.000 description 1
- 206010041243 Social avoidant behaviour Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 206010045210 Tympanic Membrane Perforation Diseases 0.000 description 1
- 208000014769 Usher Syndromes Diseases 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 208000014070 Vestibular schwannoma Diseases 0.000 description 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 description 1
- 208000004064 acoustic neuroma Diseases 0.000 description 1
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 1
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 208000027625 autoimmune inner ear disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- JUPQTSLXMOCDHR-UHFFFAOYSA-N benzene-1,4-diol;bis(4-fluorophenyl)methanone Chemical compound OC1=CC=C(O)C=C1.C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 JUPQTSLXMOCDHR-UHFFFAOYSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 208000013407 communication difficulty Diseases 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000013170 computed tomography imaging Methods 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000003412 degenerative effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 235000012489 doughnuts Nutrition 0.000 description 1
- 230000003890 fistula Effects 0.000 description 1
- UIWYJDYFSGRHKR-UHFFFAOYSA-N gadolinium atom Chemical compound [Gd] UIWYJDYFSGRHKR-UHFFFAOYSA-N 0.000 description 1
- 238000001476 gene delivery Methods 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 210000002768 hair cell Anatomy 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000022760 infectious otitis media Diseases 0.000 description 1
- 230000004968 inflammatory condition Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000012977 invasive surgical procedure Methods 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 150000002605 large molecules Chemical class 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 210000001595 mastoid Anatomy 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000002324 minimally invasive surgery Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000007372 neural signaling Effects 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 206010033103 otosclerosis Diseases 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229920002530 polyetherether ketone Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 235000008113 selfheal Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 201000000200 vestibular neuronitis Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
- A61F11/20—Ear surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00064—Constructional details of the endoscope body
- A61B1/00071—Insertion part of the endoscope body
- A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
- A61B1/00087—Tools
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/012—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor
- A61B1/015—Control of fluid supply or evacuation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/227—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for ears, i.e. otoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/84—Drainage tubes; Aspiration tips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0662—Ears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Acoustics & Sound (AREA)
- Otolaryngology (AREA)
- Psychology (AREA)
- Pulmonology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163249938P | 2021-09-29 | 2021-09-29 | |
| US63/249,938 | 2021-09-29 | ||
| PCT/US2022/044846 WO2023055719A1 (en) | 2021-09-29 | 2022-09-27 | Cochlea injection devices, systems, and methods for otology |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2022358311A1 true AU2022358311A1 (en) | 2024-04-11 |
Family
ID=85783441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2022358311A Pending AU2022358311A1 (en) | 2021-09-29 | 2022-09-27 | Cochlea injection devices, systems, and methods for otology |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240398625A1 (https=) |
| EP (1) | EP4408362A4 (https=) |
| JP (1) | JP2024535927A (https=) |
| CN (1) | CN118284390A (https=) |
| AU (1) | AU2022358311A1 (https=) |
| CA (1) | CA3233538A1 (https=) |
| WO (1) | WO2023055719A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117224207B (zh) * | 2023-09-06 | 2025-04-18 | 中国人民解放军总医院第一医学中心 | 一种可视性鼓膜穿刺针及其使用方法 |
| WO2025188524A1 (en) * | 2024-03-06 | 2025-09-12 | Spiral Therapeutics Inc. | System for treating ear disorders |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040133099A1 (en) * | 2002-12-18 | 2004-07-08 | Dyer R. Kent | Otologic nanotechnology |
| CN102186528B (zh) * | 2008-10-15 | 2013-08-07 | Med-El电气医疗器械有限公司 | 内耳给药装置 |
| US10130514B2 (en) * | 2011-09-26 | 2018-11-20 | Incube Labs, Llc | System and method for delivery of a therapeutic agent to the inner ear |
| US10821276B2 (en) * | 2012-12-14 | 2020-11-03 | The Trustees Of Columbia University In The City Of New York | System and method to locally deliver therapeutic agent to inner ear |
| US20220032020A1 (en) * | 2018-12-05 | 2022-02-03 | Cochlear Limited | Therapeutic substance storage and delivery |
| US10492670B1 (en) | 2018-12-18 | 2019-12-03 | 3Nt Medical Ltd. | Ear visualization and treatment system |
| JP7793515B2 (ja) * | 2019-11-21 | 2026-01-05 | ザ チャールズ スターク ドレイパー ラボラトリー， インク． | マイクロポンプを介した内耳への薬物の短期的及び長期的な送達用の経正円窓膜カテーテルの挿入を補助するための手工具 |
| CN115515542B (zh) * | 2020-01-24 | 2026-02-06 | 斯皮拉尔诊疗有限公司 | 用于耳科的装置、系统和方法 |
-
2022
- 2022-09-27 AU AU2022358311A patent/AU2022358311A1/en active Pending
- 2022-09-27 CA CA3233538A patent/CA3233538A1/en active Pending
- 2022-09-27 EP EP22877202.6A patent/EP4408362A4/en active Pending
- 2022-09-27 JP JP2024519397A patent/JP2024535927A/ja active Pending
- 2022-09-27 WO PCT/US2022/044846 patent/WO2023055719A1/en not_active Ceased
- 2022-09-27 CN CN202280077419.XA patent/CN118284390A/zh active Pending
- 2022-09-27 US US18/696,834 patent/US20240398625A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2024535927A (ja) | 2024-10-02 |
| EP4408362A1 (en) | 2024-08-07 |
| EP4408362A4 (en) | 2025-01-01 |
| WO2023055719A1 (en) | 2023-04-06 |
| CA3233538A1 (en) | 2023-04-06 |
| US20240398625A1 (en) | 2024-12-05 |
| CN118284390A (zh) | 2024-07-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2017261535B2 (en) | Implant device, tool, and methods relating to treatment of paranasal sinuses | |
| RU2740165C2 (ru) | Устройство для субретинального введения терапевтического средства изогнутой иглой | |
| ES2738298T3 (es) | Sistemas y métodos de suministro de fármacos, tratamiento y monitoreo | |
| CA2809948C (en) | Fluid management catheter with optical tip and methods of using same | |
| US20240398625A1 (en) | Cochlea injection devices, systems, and methods for otology | |
| CN115426990A (zh) | 通过鼓膜进入中耳和内耳的微创工具和方法 | |
| WO2021225442A1 (en) | Fluid injection device for injecting a fluid behind the tympanic membrane | |
| JP2022529950A (ja) | 誘導針および関連するカテーテル挿入装置 | |
| US20240374884A1 (en) | Microneedle Apparatus And System For Perforation Of The Round Window Membrane | |
| US20240398220A1 (en) | Endoscopic systems and methods for treating hearing loss | |
| CN114042233B (zh) | 一种脑室转流术旁通系统 | |
| RU2738627C1 (ru) | Полуавтоматическая игла для трепан-биопсии опухолей головки поджелудочной железы и дистального отдела холедоха | |
| US20250195268A1 (en) | Apparatus for subretinal administration of therapeutic agent via dual-curved needle | |
| RU2716200C1 (ru) | Эндоскопический способ установки люмбального катетера в субарахноидальное пространство | |
| JP2005211397A (ja) | 粘膜下注入針 | |
| JPWO2023055719A5 (https=) | ||
| HK40123414A (zh) | 用於经由双弯针来视网膜下施用治疗剂的装置 | |
| Maghsoudi | Air bubble barrier to syringe contamination | |
| JP2017169995A (ja) | 耳鼻科用注射針、鼓室内薬剤注入用注射針 |