AU2022326485A1 - Methods and compositions for treating cancer - Google Patents

Methods and compositions for treating cancer Download PDF

Info

Publication number
AU2022326485A1
AU2022326485A1 AU2022326485A AU2022326485A AU2022326485A1 AU 2022326485 A1 AU2022326485 A1 AU 2022326485A1 AU 2022326485 A AU2022326485 A AU 2022326485A AU 2022326485 A AU2022326485 A AU 2022326485A AU 2022326485 A1 AU2022326485 A1 AU 2022326485A1
Authority
AU
Australia
Prior art keywords
days
compound
administering
weeks
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2022326485A
Other languages
English (en)
Inventor
Steven FRUCHTMAN
Matthew PARRIS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Traws Pharma Inc
Original Assignee
Onconova Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onconova Therapeutics Inc filed Critical Onconova Therapeutics Inc
Publication of AU2022326485A1 publication Critical patent/AU2022326485A1/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/26Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2022326485A 2021-08-12 2022-08-11 Methods and compositions for treating cancer Pending AU2022326485A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163232409P 2021-08-12 2021-08-12
US63/232,409 2021-08-12
PCT/US2022/040092 WO2023018891A1 (en) 2021-08-12 2022-08-11 Methods and compositions for treating cancer

Publications (1)

Publication Number Publication Date
AU2022326485A1 true AU2022326485A1 (en) 2024-02-29

Family

ID=85200519

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2022326485A Pending AU2022326485A1 (en) 2021-08-12 2022-08-11 Methods and compositions for treating cancer

Country Status (11)

Country Link
US (1) US20240299326A1 (https=)
EP (1) EP4384498A1 (https=)
JP (1) JP2024531238A (https=)
CN (1) CN118076583A (https=)
AU (1) AU2022326485A1 (https=)
CA (1) CA3228644A1 (https=)
CO (1) CO2024002786A2 (https=)
GB (1) GB2628229A (https=)
IL (1) IL310759A (https=)
MX (1) MX2024001935A (https=)
WO (1) WO2023018891A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5156389B2 (ja) * 2005-01-05 2013-03-06 テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション 薬剤耐性増殖性疾患の治療剤
WO2014089483A1 (en) * 2012-12-07 2014-06-12 Onconova Therapeutics, Inc. Methods and compositions for treatment of cancer
JP2018530590A (ja) * 2015-10-14 2018-10-18 タリックス ファーマシューティカルズ リミテッド 表皮水疱症の処置のための方法及び組成物
CA3076610A1 (en) * 2017-09-22 2019-03-28 University Of Miami Methods and compositions for the treatment of epidermolysis bullosa

Also Published As

Publication number Publication date
WO2023018891A1 (en) 2023-02-16
US20240299326A1 (en) 2024-09-12
GB2628229A (en) 2024-09-18
MX2024001935A (es) 2024-03-21
CO2024002786A2 (es) 2024-03-18
GB202402730D0 (en) 2024-04-10
CA3228644A1 (en) 2023-02-16
CN118076583A (zh) 2024-05-24
WO2023018891A8 (en) 2023-09-21
IL310759A (en) 2024-04-01
JP2024531238A (ja) 2024-08-29
EP4384498A1 (en) 2024-06-19

Similar Documents

Publication Publication Date Title
TWI831916B (zh) 包含tno155和瑞博西尼之藥物組合
JP7025781B2 (ja) CCケモカイン受容体9(CCR9)の阻害剤と抗α4β7インテグリン遮断抗体の併用療法
EP3443962B1 (en) Quinoline derivative for treating gastric cancer
US20230372346A1 (en) Treatment regimens for exon-20 insertion mutant egfr cancers
AU2003242646A1 (en) Combinations comprising epothilones and pharmaceutical uses thereof
TW202539662A (zh) 抗腫瘤組合物
CN113018429A (zh) 治疗卵巢癌的药物组合
US20240299326A1 (en) Methods and compositions for treating cancer
CN115484944B (zh) 使用ccr9抑制剂和抗il-23阻断抗体治疗炎症性肠病的组合物和方法
CN113939315A (zh) 治疗黑色素瘤的联用药物组合物
WO2023011631A1 (zh) 治疗小细胞肺癌的药物组合
MD4879C1 (ro) Utilizare a derivatului bisamidic al acidului malonic pentru tratarea bolilor alergice şi altor boli umane şi animaliere
EP3967309B1 (en) Quinoline derivative and antibody toripalimab soft tissue sarcoma combination therapy
US20240374600A1 (en) Methods and compositions for treating cancer
US20240366610A1 (en) Methods and compositions for treating cancer
WO2023230286A2 (en) Methods and compositions for treating cancer
EP4433060A1 (en) Methods and compositions for treating cancer
US20230092001A1 (en) Furaneol glycoside compound, pharmaceutical composition thereof, preparation method therefor, and application thereof
US20240269099A1 (en) Methods and compositions for treating cancer
WO2025247187A1 (zh) 抗trop2抗体药物偶联物和抗pd-l1/cd47双特异抗体联合治疗肿瘤的用途
WO2024186641A1 (en) Methods and compositions for treating cancer
WO2023230220A2 (en) Methods and compositions for treating cancer
WO2024107661A2 (en) Methods and compositions for treating cancer
CN120131937A (zh) 治疗骨与软组织肿瘤的药物组合
WO2025247186A1 (zh) 抗trop2抗体药物偶联物和vegf-a抑制剂联合治疗肿瘤的用途