AU2022229350A1 - Arylsulfonamides as orexin receptor agonists - Google Patents

Arylsulfonamides as orexin receptor agonists Download PDF

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AU2022229350A1
AU2022229350A1 AU2022229350A AU2022229350A AU2022229350A1 AU 2022229350 A1 AU2022229350 A1 AU 2022229350A1 AU 2022229350 A AU2022229350 A AU 2022229350A AU 2022229350 A AU2022229350 A AU 2022229350A AU 2022229350 A1 AU2022229350 A1 AU 2022229350A1
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compound
alkyl
disease
regulation
sleep
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Dehui Zhang
Yanan Zhang
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RTI International Inc
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RTI International Inc
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    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ ARYLSULFONAMIDES AS OREXIN RECEPTOR AGONISTS