AU2021414296A1 - Circulating transcription factor analysis - Google Patents
Circulating transcription factor analysis Download PDFInfo
- Publication number
- AU2021414296A1 AU2021414296A1 AU2021414296A AU2021414296A AU2021414296A1 AU 2021414296 A1 AU2021414296 A1 AU 2021414296A1 AU 2021414296 A AU2021414296 A AU 2021414296A AU 2021414296 A AU2021414296 A AU 2021414296A AU 2021414296 A1 AU2021414296 A1 AU 2021414296A1
- Authority
- AU
- Australia
- Prior art keywords
- dna
- transcription factor
- subject
- fragment
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2545/00—Reactions characterised by their quantitative nature
- C12Q2545/10—Reactions characterised by their quantitative nature the purpose being quantitative analysis
- C12Q2545/114—Reactions characterised by their quantitative nature the purpose being quantitative analysis involving a quantitation step
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/131—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a member of a cognate binding pair, i.e. extends to antibodies, haptens, avidin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063131722P | 2020-12-29 | 2020-12-29 | |
| US63/131,722 | 2020-12-29 | ||
| PCT/EP2021/087813 WO2022144407A1 (en) | 2020-12-29 | 2021-12-29 | Circulating transcription factor analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2021414296A1 true AU2021414296A1 (en) | 2023-07-27 |
Family
ID=79927307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2021414296A Pending AU2021414296A1 (en) | 2020-12-29 | 2021-12-29 | Circulating transcription factor analysis |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240318226A1 (https=) |
| EP (1) | EP4271833A1 (https=) |
| JP (1) | JP2024501063A (https=) |
| KR (1) | KR20230132485A (https=) |
| CN (1) | CN116917496A (https=) |
| AU (1) | AU2021414296A1 (https=) |
| CA (1) | CA3206465A1 (https=) |
| IL (1) | IL303977A (https=) |
| MX (1) | MX2023007818A (https=) |
| TW (1) | TW202242130A (https=) |
| WO (1) | WO2022144407A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115851951A (zh) * | 2022-12-12 | 2023-03-28 | 广州优泽生物技术有限公司 | 含多组学标志物组合物的早期肝癌检测模型构建及试剂盒 |
| WO2024133222A1 (en) * | 2022-12-19 | 2024-06-27 | Belgian Volition Srl | Assessment of biological samples for nucleic acid analysis |
| GB202303562D0 (en) * | 2023-03-10 | 2023-04-26 | Belgian Volition Sprl | Sample collection for liquid biopsy |
| WO2025073909A1 (en) | 2023-10-04 | 2025-04-10 | Belgian Volition Srl | Pcr method for detecting ctcf occupied cfdna fragments |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0319376D0 (en) | 2003-08-18 | 2003-09-17 | Chroma Therapeutics Ltd | Histone modification detection |
| GB201115098D0 (en) | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes containing histone variants |
| GB201115095D0 (en) | 2011-09-01 | 2011-10-19 | Singapore Volition Pte Ltd | Method for detecting nucleosomes containing nucleotides |
| PT2788767T (pt) | 2011-12-07 | 2017-12-06 | Belgian Volition Sprl | Método de detecção de adutos de nucleosoma |
| IL305462A (en) | 2015-07-23 | 2023-10-01 | Univ Hong Kong Chinese | DNA fragmentation pattern analysis suitable clean |
| LT3334841T (lt) * | 2015-08-12 | 2020-02-10 | Cemm - Forschungszentrum Für Molekulare Medizin Gmbh | Nukleorūgščių tyrimo būdai |
| WO2017034970A1 (en) * | 2015-08-21 | 2017-03-02 | The General Hospital Corporation | Combinatorial single molecule analysis of chromatin |
| GB201604806D0 (en) | 2016-03-22 | 2016-05-04 | Singapore Volition Pte Ltd | Method of identifying a cancer of unknown origin |
| CN112119166B (zh) * | 2018-03-13 | 2025-08-22 | 耶路撒冷希伯来大学伊萨姆研发有限公司 | 无细胞dna染色质免疫沉淀的诊断应用 |
| WO2020206143A1 (en) * | 2019-04-05 | 2020-10-08 | Claret Bioscience, Llc | Methods and compositions for analyzing nucleic acid |
-
2021
- 2021-12-28 TW TW110149064A patent/TW202242130A/zh unknown
- 2021-12-29 KR KR1020237025577A patent/KR20230132485A/ko active Pending
- 2021-12-29 MX MX2023007818A patent/MX2023007818A/es unknown
- 2021-12-29 EP EP21847723.0A patent/EP4271833A1/en active Pending
- 2021-12-29 US US18/260,018 patent/US20240318226A1/en active Pending
- 2021-12-29 WO PCT/EP2021/087813 patent/WO2022144407A1/en not_active Ceased
- 2021-12-29 CA CA3206465A patent/CA3206465A1/en active Pending
- 2021-12-29 AU AU2021414296A patent/AU2021414296A1/en active Pending
- 2021-12-29 IL IL303977A patent/IL303977A/en unknown
- 2021-12-29 CN CN202180094755.0A patent/CN116917496A/zh active Pending
- 2021-12-29 JP JP2023539832A patent/JP2024501063A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20230132485A (ko) | 2023-09-15 |
| MX2023007818A (es) | 2023-09-05 |
| WO2022144407A1 (en) | 2022-07-07 |
| CA3206465A1 (en) | 2022-07-07 |
| CN116917496A (zh) | 2023-10-20 |
| IL303977A (en) | 2023-08-01 |
| JP2024501063A (ja) | 2024-01-10 |
| TW202242130A (zh) | 2022-11-01 |
| EP4271833A1 (en) | 2023-11-08 |
| US20240318226A1 (en) | 2024-09-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20240318226A1 (en) | Circulating transcription factor analysis | |
| US11193939B2 (en) | Method for detecting nucleosome adducts | |
| CN114901832A (zh) | 分离循环核小体的方法 | |
| Paakinaho et al. | SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites | |
| US20240318255A1 (en) | Transcription factor binding site analysis of nucleosome depleted circulating cell free chromatin fragments | |
| JP6777757B2 (ja) | 癌検出のためのヌクレオソーム−転写因子複合体の使用 | |
| Belli et al. | FOXL2C134W-induced CYP19 expression via cooperation with SMAD3 in HGrC1 cells | |
| EA052463B1 (ru) | Анализ циркулирующих факторов транскрипции | |
| WO2025073909A1 (en) | Pcr method for detecting ctcf occupied cfdna fragments | |
| HK40055426A (en) | Use of dna-transcription factor complexes for cancer detection | |
| CN102732515A (zh) | 一种核苷酸序列及其用途 | |
| HK1249176B (en) | Method for detecting nucleosome adducts | |
| Rodriguez | Estrogen Represses Target Genes through Epigenetic Modification of Proximal and Distal Elements | |
| HK40003771B (en) | Use of nucleosome-transcription factor complexes for cancer detection |