AU2021373797A1 - Methods for allogeneic hematopoietic stem cell transplantation - Google Patents

Methods for allogeneic hematopoietic stem cell transplantation Download PDF

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Publication number
AU2021373797A1
AU2021373797A1 AU2021373797A AU2021373797A AU2021373797A1 AU 2021373797 A1 AU2021373797 A1 AU 2021373797A1 AU 2021373797 A AU2021373797 A AU 2021373797A AU 2021373797 A AU2021373797 A AU 2021373797A AU 2021373797 A1 AU2021373797 A1 AU 2021373797A1
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population
cells
administered
tregs
patient
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AU2021373797A
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AU2021373797A9 (en
Inventor
Nathaniel FERNHOFF
Scott Killian
Scott Mcclellan
Everett Hurteau Meyer
Robert S. Negrin
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Orca Biosystems Inc
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Orca Biosystems Inc
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Publication of AU2021373797A1 publication Critical patent/AU2021373797A1/en
Publication of AU2021373797A9 publication Critical patent/AU2021373797A9/en
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
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    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells

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  • Cell Biology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
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  • Transplantation (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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AU2021373797A 2020-11-04 2021-11-04 Methods for allogeneic hematopoietic stem cell transplantation Pending AU2021373797A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063109811P 2020-11-04 2020-11-04
US63/109,811 2020-11-04
US202063121534P 2020-12-04 2020-12-04
US202063121453P 2020-12-04 2020-12-04
US202063121742P 2020-12-04 2020-12-04
US63/121,742 2020-12-04
US63/121,534 2020-12-04
US63/121,453 2020-12-04
PCT/US2021/058141 WO2022098926A1 (en) 2020-11-04 2021-11-04 Methods for allogeneic hematopoietic stem cell transplantation

Publications (2)

Publication Number Publication Date
AU2021373797A1 true AU2021373797A1 (en) 2023-06-08
AU2021373797A9 AU2021373797A9 (en) 2024-02-08

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ID=81457370

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Application Number Title Priority Date Filing Date
AU2021373797A Pending AU2021373797A1 (en) 2020-11-04 2021-11-04 Methods for allogeneic hematopoietic stem cell transplantation

Country Status (6)

Country Link
US (1) US20230372393A1 (enExample)
EP (1) EP4240346A4 (enExample)
JP (1) JP2023549114A (enExample)
AU (1) AU2021373797A1 (enExample)
CA (1) CA3197122A1 (enExample)
WO (1) WO2022098926A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3012854T3 (en) 2018-02-08 2025-04-10 Univ Leland Stanford Junior Allogenic hematopoietic stem cell transplantation
EP4426318A4 (en) * 2021-11-04 2025-11-19 Orca Biosystems Inc THERAPEUTIC COMPOSITIONS AND TRANSPLANTATION PROCESSES OF ALLOGENEIC HEMATOPOIETIC CELLS
AU2023252879A1 (en) * 2022-04-15 2024-11-21 Orca Biosystems, Inc. Methods for allogeneic hematopoietic stem cell transplantation
EP4611778A4 (en) * 2022-11-03 2026-07-15 Orca Biosystems Inc COMPOSITION AND METHODS FOR HEMATOPOIETIC STEM CELL TRANSPLANTS
WO2025054336A1 (en) * 2023-09-05 2025-03-13 Orca Biosystems, Inc. Compositions and methods for treating cancer using cell therapies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11534460B2 (en) * 2015-05-11 2022-12-27 University Health Network Method for expansion of double negative regulatory T cells
WO2018106610A1 (en) * 2016-12-05 2018-06-14 The Regents Of The University Of California Immunomagnetic bead-based method to enrich stem cells from whole hematopoietic tissue
CN118662615A (zh) * 2017-03-15 2024-09-20 浩康生物系统公司 用于造血干细胞移植的组合物和方法
ES3012854T3 (en) * 2018-02-08 2025-04-10 Univ Leland Stanford Junior Allogenic hematopoietic stem cell transplantation

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Publication number Publication date
WO2022098926A9 (en) 2022-06-30
WO2022098926A1 (en) 2022-05-12
EP4240346A1 (en) 2023-09-13
JP2023549114A (ja) 2023-11-22
AU2021373797A9 (en) 2024-02-08
US20230372393A1 (en) 2023-11-23
CA3197122A1 (en) 2022-05-12
EP4240346A4 (en) 2024-08-14

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