AU2021213131B2 - Systems and methods for processing electronic images for biomarker localization - Google Patents

Systems and methods for processing electronic images for biomarker localization Download PDF

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Publication number
AU2021213131B2
AU2021213131B2 AU2021213131A AU2021213131A AU2021213131B2 AU 2021213131 B2 AU2021213131 B2 AU 2021213131B2 AU 2021213131 A AU2021213131 A AU 2021213131A AU 2021213131 A AU2021213131 A AU 2021213131A AU 2021213131 B2 AU2021213131 B2 AU 2021213131B2
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tumor
training
region
digital images
machine learning
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AU2021213131A1 (en
Inventor
Belma DOGDAS
Thomas Fuchs
Leo Grady
Christopher Kanan
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Paige AI Inc
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Paige AI Inc
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20081Training; Learning
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20084Artificial neural networks [ANN]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30096Tumor; Lesion
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00ICT specially adapted for the handling or processing of medical images
    • G16H30/40ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Data Mining & Analysis (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Databases & Information Systems (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Quality & Reliability (AREA)
  • Image Analysis (AREA)
  • Image Processing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
AU2021213131A 2020-01-28 2021-01-27 Systems and methods for processing electronic images for biomarker localization Active AU2021213131B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062966723P 2020-01-28 2020-01-28
US62/966,723 2020-01-28
PCT/US2021/015323 WO2021154878A1 (fr) 2020-01-28 2021-01-27 Systèmes et procédés de traitement d'images électroniques pour la localisation de biomarqueurs

Publications (2)

Publication Number Publication Date
AU2021213131A1 AU2021213131A1 (en) 2022-09-01
AU2021213131B2 true AU2021213131B2 (en) 2023-02-02

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AU2021213131A Active AU2021213131B2 (en) 2020-01-28 2021-01-27 Systems and methods for processing electronic images for biomarker localization

Country Status (7)

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US (3) US11182900B2 (fr)
EP (1) EP4097738A1 (fr)
JP (1) JP7376882B2 (fr)
CN (1) CN114981899A (fr)
AU (1) AU2021213131B2 (fr)
CA (1) CA3161533C (fr)
WO (1) WO2021154878A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3963508B1 (fr) * 2019-05-03 2024-09-18 Huron Technologies International Inc. Système de diagnostic d'images, et ses procédés d'exploitation
EP4097738A1 (fr) * 2020-01-28 2022-12-07 PAIGE.AI, Inc. Systèmes et procédés de traitement d'images électroniques pour la localisation de biomarqueurs
US20230116379A1 (en) 2021-09-24 2023-04-13 PAIGE.AI, Inc. Systems and methods to process electronic images to identify tumor subclones and relationships among subclones
US20230307137A1 (en) * 2022-03-25 2023-09-28 GE Precision Healthcare LLC System and method for detecting recurrence of a disease
CN115330949B (zh) * 2022-08-16 2024-04-05 中山大学附属第一医院 一种肝细胞癌侵袭边缘预测方法及系统
CN115295154B (zh) * 2022-10-08 2023-02-03 北京肿瘤医院(北京大学肿瘤医院) 肿瘤免疫治疗疗效预测方法、装置、电子设备及存储介质

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160123964A1 (en) * 2014-11-05 2016-05-05 The Regents Of The University Of California Methods for stratifying non-responders to therapies that block pd1/pdl1 axis
US20190113423A1 (en) * 2015-12-02 2019-04-18 Clearlight Diagnostics, LLC Methods for preparing and analyzing tumor tissue samples for detection and monitoring of cancers

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3365682B1 (fr) * 2015-10-23 2020-10-07 Novartis AG Système permettant d'obtenir des proximités spatiales de cellule à cellule
AU2016369603A1 (en) * 2015-12-18 2018-07-05 Clear Gene, Inc. Methods, compositions, kits and devices for rapid analysis of biological markers
KR102511024B1 (ko) * 2016-03-15 2023-03-16 오리존 지노믹스 에스.에이. 고형 종양의 치료에 사용하기 위한 lsd1 억제제의 조합물
WO2017198790A1 (fr) * 2016-05-18 2017-11-23 F. Hoffmann-La Roche Ag Mesure de proximité de tumeur
US10282588B2 (en) * 2016-06-09 2019-05-07 Siemens Healthcare Gmbh Image-based tumor phenotyping with machine learning from synthetic data
EP3523779A1 (fr) 2016-10-07 2019-08-14 Ventana Medical Systems, Inc. Système de pathologie numérique et flux de travail associé pour fournir une analyse d'image à glissement total visualisée
WO2018086985A1 (fr) 2016-11-10 2018-05-17 F. Hoffmann-La Roche Ag Classification de tumeur basée sur la distance
US11835524B2 (en) 2017-03-06 2023-12-05 University Of Southern California Machine learning for digital pathology
GB2567155B (en) * 2017-10-02 2022-03-02 Room4 Group Ltd Histopathological image analysis
WO2019100032A2 (fr) * 2017-11-17 2019-05-23 Mayo Foundation For Medical Education And Research Procédés d'utilisation de modèles d'apprentissage automatique et mécanistes pour la cartographie de caractéristiques biologiques avec irm multiparamétrique
US10748040B2 (en) * 2017-11-20 2020-08-18 Kavya Venkata Kota Sai KOPPARAPU System and method for automatic assessment of cancer
EP3752979A1 (fr) 2018-02-12 2020-12-23 F. Hoffmann-La Roche AG Transformation d'images numériques de pathologie
EP3769282B1 (fr) 2018-03-23 2023-08-23 Memorial Sloan Kettering Cancer Center Systèmes et procédés d'apprentissage à instances multiples pour la classification et la localisation dans l'imagerie biomédicale
CA3133826A1 (fr) 2019-03-26 2020-10-01 Tempus Labs, Inc. Determination de biomarqueurs a partir d'images de lames histopathologiques
EP4097738A1 (fr) * 2020-01-28 2022-12-07 PAIGE.AI, Inc. Systèmes et procédés de traitement d'images électroniques pour la localisation de biomarqueurs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160123964A1 (en) * 2014-11-05 2016-05-05 The Regents Of The University Of California Methods for stratifying non-responders to therapies that block pd1/pdl1 axis
US20190113423A1 (en) * 2015-12-02 2019-04-18 Clearlight Diagnostics, LLC Methods for preparing and analyzing tumor tissue samples for detection and monitoring of cancers

Also Published As

Publication number Publication date
WO2021154878A1 (fr) 2021-08-05
US20220130041A1 (en) 2022-04-28
CA3161533A1 (fr) 2021-08-05
AU2021213131A1 (en) 2022-09-01
US11481898B2 (en) 2022-10-25
JP2023506579A (ja) 2023-02-16
JP7376882B2 (ja) 2023-11-09
CA3161533C (fr) 2023-08-29
US20210233236A1 (en) 2021-07-29
US11182900B2 (en) 2021-11-23
EP4097738A1 (fr) 2022-12-07
CN114981899A (zh) 2022-08-30
US20230025189A1 (en) 2023-01-26

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