AU2020388534A1 - Device and method for detecting of brain injury in a subject - Google Patents

Device and method for detecting of brain injury in a subject Download PDF

Info

Publication number
AU2020388534A1
AU2020388534A1 AU2020388534A AU2020388534A AU2020388534A1 AU 2020388534 A1 AU2020388534 A1 AU 2020388534A1 AU 2020388534 A AU2020388534 A AU 2020388534A AU 2020388534 A AU2020388534 A AU 2020388534A AU 2020388534 A1 AU2020388534 A1 AU 2020388534A1
Authority
AU
Australia
Prior art keywords
sample
glycan
subject
detector
brain injury
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2020388534A
Other languages
English (en)
Inventor
Oskar HAAVISTO
Adrian Harel
Martti KAASALAINEN
Mårten KVIST
Lasse VÄLIMAA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicortex Finland Oy
Original Assignee
Medicortex Finland Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicortex Finland Oy filed Critical Medicortex Finland Oy
Publication of AU2020388534A1 publication Critical patent/AU2020388534A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064Evaluating the brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • AHUMAN NECESSITIES
    • A42HEADWEAR
    • A42BHATS; HEAD COVERINGS
    • A42B3/00Helmets; Helmet covers ; Other protective head coverings
    • A42B3/04Parts, details or accessories of helmets
    • A42B3/0406Accessories for helmets
    • A42B3/0433Detecting, signalling or lighting devices
    • A42B3/046Means for detecting hazards or accidents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B10/0051Devices for taking samples of body liquids for taking saliva or sputum samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B10/0064Devices for taking samples of body liquids for taking sweat or sebum samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B10/007Devices for taking samples of body liquids for taking urine samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076Diagnosing or monitoring particular conditions of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802Sensor mounted on worn items
    • A61B5/6803Head-worn items, e.g. helmets, masks, headphones or goggles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6814Head
    • A61B5/682Mouth, e.g., oral cavity; tongue; Lips; Teeth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7264Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B2010/0067Tear or lachrymal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7282Event detection, e.g. detecting unique waveforms indicative of a medical condition

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Physiology (AREA)
  • Artificial Intelligence (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Psychology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mathematical Physics (AREA)
  • Fuzzy Systems (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Evolutionary Computation (AREA)
  • Signal Processing (AREA)
AU2020388534A 2019-11-22 2020-11-03 Device and method for detecting of brain injury in a subject Pending AU2020388534A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20196004A FI20196004A1 (en) 2019-11-22 2019-11-22 Apparatus and method for detecting brain injury in a subject
FI20196004 2019-11-22
PCT/FI2020/050719 WO2021099677A1 (fr) 2019-11-22 2020-11-03 Dispositif et procédé de détection d'une lésion cérébrale chez un sujet

Publications (1)

Publication Number Publication Date
AU2020388534A1 true AU2020388534A1 (en) 2022-04-07

Family

ID=73401541

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020388534A Pending AU2020388534A1 (en) 2019-11-22 2020-11-03 Device and method for detecting of brain injury in a subject

Country Status (4)

Country Link
KR (1) KR20220001822U (fr)
AU (1) AU2020388534A1 (fr)
FI (2) FI20196004A1 (fr)
WO (1) WO2021099677A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210311043A1 (en) * 2020-04-06 2021-10-07 Medicortex Finland Oy Method for determining a lectin-binding glycan indicative to traumatic brain injury
EP4220165A1 (fr) * 2022-01-31 2023-08-02 HES-SO Valais-Wallis Procédé et dispositif de détection de lésions traumatiques du cerveau
FI130428B (en) * 2022-02-22 2023-08-24 Medicortex Finland Oy A method for detecting tissue damage

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20155280A (fi) * 2015-04-15 2016-10-16 Medicortex Finland Oy Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita
US10244971B2 (en) * 2015-05-12 2019-04-02 International Business Machines Corporation Mouthguard for analysis of biomarkers for traumatic brain injury
CN211905389U (zh) * 2017-02-21 2020-11-10 迈迪科泰斯芬兰公司 非侵入性脑损伤诊断装置
CA3079832A1 (fr) * 2017-10-23 2019-05-02 Nautilus Biotechnology, Inc. Procedes et systemes d'identification de proteines

Also Published As

Publication number Publication date
FI13179Y1 (fi) 2022-05-12
KR20220001822U (ko) 2022-07-26
WO2021099677A1 (fr) 2021-05-27
FI20196004A1 (en) 2021-05-23

Similar Documents

Publication Publication Date Title
US20200371093A1 (en) Prognostic and Diagnostic Glycan-Based Biomarkers of Brain Damage
Ates et al. Integrated devices for non‐invasive diagnostics
US9686395B2 (en) Apparatus and method for point-of-collection measurement of a biomolecular reaction
WO2021099677A1 (fr) Dispositif et procédé de détection d'une lésion cérébrale chez un sujet
KR100841355B1 (ko) 무동력 혈액분리수단을 구비한 바이오센서 칩
CN211905389U (zh) 非侵入性脑损伤诊断装置
Pittman et al. Saliva-based microfluidic point-of-care diagnostic
Silva-Neto et al. Recent advances on paper-based microfluidic devices for bioanalysis
Lakshmi et al. Oral fluid-based biosensors: A novel method for rapid and noninvasive diagnosis
Himawan et al. Where microneedle meets biomarkers: futuristic application for diagnosing and monitoring localized external organ diseases
Brunauer et al. Integrated paper-based sensing devices for diagnostic applications
Ko et al. Salivary glucose measurement: a holy ground for next generation of non-invasive diabetic monitoring
US20210132049A1 (en) Simultaneous Parallel Signal Amplification and Analyte-Ligand Capture Functions
Yadav et al. Diagnostic methods employing kidney biomarkers clinching biosensors as promising tool
Mohammadi et al. Recent advances in aptamer-based platforms for cortisol hormone monitoring
KR20200049647A (ko) 반려동물에서 종양질병의 보조적 진단을 위한 바이오마커 검사방법
EP3736563A1 (fr) Appareil de test portable portable avec aptamère pour détecter les biomarqueurs cardiaques
Mollarasouli et al. Low-molecular-weight biomarkers: Types and detection strategies
CN111665350A (zh) 一种用于血液巡航的纳米生物监测器
EP4220165A1 (fr) Procédé et dispositif de détection de lésions traumatiques du cerveau
Sesay et al. Biomarkers in Health Care
Sunil et al. Noninvasive biomarker sensors using surface-enhanced Raman spectroscopy
Li Microfluidics integrated biosensors for healthcare monitoring
Rodgers et al. Body-Worn Microfluidic Sensors
GB2604048A (en) Method and assay kit to detect an analyte

Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: APPLICATION IS TO PROCEED UNDER THE NUMBER 2020104474