AU2020361511B2 - Otic formulations, methods and devices - Google Patents

Otic formulations, methods and devices

Info

Publication number
AU2020361511B2
AU2020361511B2 AU2020361511A AU2020361511A AU2020361511B2 AU 2020361511 B2 AU2020361511 B2 AU 2020361511B2 AU 2020361511 A AU2020361511 A AU 2020361511A AU 2020361511 A AU2020361511 A AU 2020361511A AU 2020361511 B2 AU2020361511 B2 AU 2020361511B2
Authority
AU
Australia
Prior art keywords
formulation
ear
cps
marbofloxacin
ear canal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2020361511A
Other languages
English (en)
Other versions
AU2020361511A1 (en
Inventor
Gail L. Dempsey
Dorothea A. Erxleben
Douglas I. Hepler
Neil E. Paulsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dechra Veterinary Products LLC
Original Assignee
Dechra Veterinary Products LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dechra Veterinary Products LLC filed Critical Dechra Veterinary Products LLC
Publication of AU2020361511A1 publication Critical patent/AU2020361511A1/en
Assigned to DECHRA VETERINARY PRODUCTS, LLC reassignment DECHRA VETERINARY PRODUCTS, LLC Request for Assignment Assignors: PIEDMONT ANIMAL HEALTH INC.
Application granted granted Critical
Publication of AU2020361511B2 publication Critical patent/AU2020361511B2/en
Priority to AU2026201359A priority Critical patent/AU2026201359A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more nitrogen atoms in the same ring, e.g. oxadiazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0662—Ears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
AU2020361511A 2019-10-11 2020-10-08 Otic formulations, methods and devices Active AU2020361511B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2026201359A AU2026201359A1 (en) 2019-10-11 2026-02-24 Otic formulations, methods and devices

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962914301P 2019-10-11 2019-10-11
US62/914,301 2019-10-11
PCT/US2020/054770 WO2021072063A1 (en) 2019-10-11 2020-10-08 Otic formulations, methods and devices

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2026201359A Division AU2026201359A1 (en) 2019-10-11 2026-02-24 Otic formulations, methods and devices

Publications (2)

Publication Number Publication Date
AU2020361511A1 AU2020361511A1 (en) 2022-04-14
AU2020361511B2 true AU2020361511B2 (en) 2025-12-18

Family

ID=75383696

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2020361511A Active AU2020361511B2 (en) 2019-10-11 2020-10-08 Otic formulations, methods and devices
AU2026201359A Pending AU2026201359A1 (en) 2019-10-11 2026-02-24 Otic formulations, methods and devices

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2026201359A Pending AU2026201359A1 (en) 2019-10-11 2026-02-24 Otic formulations, methods and devices

Country Status (6)

Country Link
US (3) US11986483B2 (enExample)
EP (1) EP4041153A4 (enExample)
JP (2) JP7680653B2 (enExample)
CN (3) CN114450010A (enExample)
AU (2) AU2020361511B2 (enExample)
WO (1) WO2021072063A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4041153A4 (en) * 2019-10-11 2023-10-25 Piedmont Animal Health Inc. OTIC FORMULATIONS, METHODS AND DEVICES

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130178801A1 (en) * 2012-01-10 2013-07-11 Entrx LLC Otic formulations, methods and devices

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070078116A1 (en) * 2003-08-20 2007-04-05 Fairfield Clinical Trials, Llc Method of treatment of otitis externa
US8003616B2 (en) * 2004-04-23 2011-08-23 Albert Rory J Composition for the treatment of ear infections and method
US7858115B2 (en) * 2004-06-24 2010-12-28 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
CA2576589C (en) * 2004-08-13 2013-11-12 Schering-Plough Ltd. Pharmaceutical formulation comprising an antibiotic, a triazole and a corticosteroid
US8318817B2 (en) 2008-07-21 2012-11-27 Otonomy, Inc. Controlled release antimicrobial compositions and methods for the treatment of otic disorders
UA111147C2 (uk) * 2009-11-11 2016-04-11 Байєр Б.В. Способи та композиції для лікування або профілактики зовнішнього отиту
US9849126B2 (en) * 2013-01-03 2017-12-26 Entrx LLC Sterile otic formulations
CN105263525A (zh) * 2013-04-12 2016-01-20 维奥姆生物科学有限公司 抗微生物剂的组合物和制剂、它们的方法以及用于治疗微生物感染的方法
EP4041153A4 (en) * 2019-10-11 2023-10-25 Piedmont Animal Health Inc. OTIC FORMULATIONS, METHODS AND DEVICES

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130178801A1 (en) * 2012-01-10 2013-07-11 Entrx LLC Otic formulations, methods and devices

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BENSIGNOR, E. et al. "Comparison of an antifungal agent with a mixture of antifungal, antibiotic and corticosteroid agents for the treatment of Malassezia species otitis in dogs" VETERINARY RECORD (2006) vol. 158, no. 6, pages 193-195 *
VETERINARY DERMATOLOGY: "Plenary Session Abstracts: Thursday Morning, 26th July Theme: ALLERGY", VETERINARY DERMATOLOGY, vol. 23, no. Suppl. 1, 1 January 2012, pages 2-104, abstracts P-100 and P-101 *

Also Published As

Publication number Publication date
CA3153832A1 (en) 2021-04-15
US20240285651A1 (en) 2024-08-29
US12491189B2 (en) 2025-12-09
JP2025098165A (ja) 2025-07-01
JP2022551499A (ja) 2022-12-09
US20260060990A1 (en) 2026-03-05
JP7680653B2 (ja) 2025-05-21
US11986483B2 (en) 2024-05-21
CN120837502A (zh) 2025-10-28
EP4041153A4 (en) 2023-10-25
CN120284977A (zh) 2025-07-11
EP4041153A1 (en) 2022-08-17
CN114450010A (zh) 2022-05-06
AU2020361511A1 (en) 2022-04-14
WO2021072063A1 (en) 2021-04-15
US20210106597A1 (en) 2021-04-15
AU2026201359A1 (en) 2026-03-12

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: DECHRA VETERINARY PRODUCTS, LLC

Free format text: FORMER APPLICANT(S): PIEDMONT ANIMAL HEALTH INC.

FGA Letters patent sealed or granted (standard patent)