AU2018101890A4 - Pharmaceutical intermediate high purity anhydrous ethanol production plant - Google Patents
Pharmaceutical intermediate high purity anhydrous ethanol production plant Download PDFInfo
- Publication number
- AU2018101890A4 AU2018101890A4 AU2018101890A AU2018101890A AU2018101890A4 AU 2018101890 A4 AU2018101890 A4 AU 2018101890A4 AU 2018101890 A AU2018101890 A AU 2018101890A AU 2018101890 A AU2018101890 A AU 2018101890A AU 2018101890 A4 AU2018101890 A4 AU 2018101890A4
- Authority
- AU
- Australia
- Prior art keywords
- high purity
- anhydrous ethanol
- pharmaceutical intermediate
- ethanol production
- production plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
- C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
- C07C29/80—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by distillation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Pharmaceutical intermediate high purity anhydrous ethanol production plant Abstract Pharmaceutical intermediate high purity anhydrous ethanol production plant, including: industrial furnace (B10), distillation still (ElOl), rectifying column (E102), ultra-clean filter (LIO); among them, distillation still (ElOl) is connected respectively to industrial furnace (B10) and rectifying column (E102), rectifying 10 column (E102) is connected to ultra-clean filter (LIO); among them, nominal volume of distillation still (E101) is 4200-4400 L. Figure 1 3101Ii i~hed El 01 E102"pckgn Figure 1
Description
Pharmaceutical intermediate high purity anhydrous ethanol production plant
FIELD OF THE INVENTION
The present invention relates to a kind of pharmaceutical synthesis plant, more particularly, relates to pharmaceutical intermediate high purity anhydrous ethanol production plant.
GENERAL BACKGROUND
High purity anhydrous ethanol can be used in pharmaceutical intermediate, and also widely used in various synthetic fields such as coatings, hygienic products, cosmetics and oils, accounting for about 50% of total ethanol consumption. High purity anhydrous ethanol is an important basic chemical raw material used in the manufacture of acetaldehyde, ethylene, ethylamine, ethyl acetate, acetic acid, ethyl chloride, etc., and can derive many intermediates of medicine, dyes, paints, spices, synthetic rubber, detergents, pesticides and other products. It can also be used as a solvent extraction, binding agent, perfume solvent, flavoring agent and preservative. Most of the existing production plant processes are complex. Thus, as a pharmaceutical intermediate, the advantages and disadvantages of production equipment of high purity anhydrous ethanol have a great economic significant for improving product quality and reducing the by-product contents.
SUMMARY
The purpose of the present invention is to provide pharmaceutical intermediate high purity anhydrous ethanol production plant, including: industrial furnace (Bl01), distillation still (E101), rectifying column (E102), ultra-clean filter (L101); among them, distillation still (El01) is connected respectively to industrial furnace (Bl01) and rectifying column (El02), rectifying column (El02) is connected to ultra-clean filter (L101); among them, nominal volume of distillation still (E101) is 4200-4400 L, outer pot diameter of rectifying column (El02) is 1500-1600 mm, microporous membrane diameter of ultra-clean filter (L101) is 1.5-1.7 pm.
Pharmaceutical intermediate high purity anhydrous ethanol production plant, the
2018101890 30 Nov 2018 production process is: burnt calcium oxide in industrial furnace B101. Put the calcined calcium oxide into distiller E101 with 95% analytical grade ethanol, controlled the ratio at 5:1, refluxed for 2-3 h, examined by dehydration test. After passing dehydration test, transferred the product to the rectifying column El02 for 5 rectification, discarded some of the low, high boiling point materials. That is, high-purity specifications ethanol. Filtered the obtained distillation section in ultra-clean filter LI01 with the porous membrane filter, then subpackaged and got the finished product. The advantages of this invention are that the reaction time is reduced and the reaction rate is improved.
DESCRIPTION OF THE DRAWINGS
Figure 1 is pharmaceutical intermediate high purity anhydrous ethanol production plant.
Include: industrial furnace (B101), distillation still (E101), rectifying column (El02), ultra-clean filter (LI01);
DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS
The following examples with reference to specific embodiments of the present invention are further illustrated:
Embodiment 1
Raw materials and dosages
| Calcium oxide | Pure chemical | 50 | Ethanol | Industrial | 130 |
| grade, 95% |
Pharmaceutical intermediate high purity anhydrous ethanol production plant, including: industrial furnace (B101), distillation still (E101), rectifying column (E102), ultra-clean filter (LI01); among them, distillation still (El01) is connected respectively to industrial furnace (B101) and rectifying column (E102), rectifying column (E102) is connected to ultra-clean filter (L101); among them, nominal volume of distillation still (E101) is 4200 L, outer pot diameter of rectifying column (E102) is 1500 mm, microporous membrane diameter of ultra-clean filter (L101) is 1.5 pm.
Pharmaceutical intermediate high purity anhydrous ethanol production plant, the
2018101890 30 Nov 2018 production process is: burnt calcium oxide in industrial furnace B101. Put the calcined calcium oxide into distiller E101 with 95% analytical grade ethanol, controlled the ratio at 5:1, refluxed for 2 h, examined by dehydration test. After passing dehydration test, transferred the product to the rectifying column El02 for rectification, discarded 5 some of the low, high boiling point materials. That is, high-purity specifications ethanol. Filtered the obtained distillation section in ultra-clean filter L101 with the porous membrane filter, then subpackaged and got the finished product.
The qualities of the product are as follows:
| Exterior | Colorless transparent liquid | Refractive index | 1.362 |
| Boiling point | 78 °C | Density (20 °C) | 0.791 g/mL |
Embodiment 2
Raw materials and dosages
| Calcium oxide | Pure chemical | 60 | Ethanol | Industrial | 150 |
| grade, 95% |
Pharmaceutical intermediate high purity anhydrous ethanol production plant, including: industrial furnace (B101), distillation still (E101), rectifying column (E102), ultra-clean filter (LI01); among them, distillation still (El01) is connected respectively to industrial furnace (B101) and rectifying column (E102), rectifying column (E102) is connected to ultra-clean filter (L101); among them, nominal volume of distillation still (E101) is 4400 L, outer pot diameter of rectifying column (E102) is 1600 mm, microporous membrane diameter of ultra-clean filter (L101) is 1.7 pm.
Pharmaceutical intermediate high purity anhydrous ethanol production plant, the production process is: burnt calcium oxide in industrial furnace B101. Put the calcined calcium oxide into distiller E101 with 95% analytical grade ethanol, controlled the ratio at 5:1, refluxed for 3 h, examined by dehydration test. After passing dehydration test, transferred the product to the rectifying column El02 for rectification, discarded some of the low, high boiling point materials. That is, high-purity specifications ethanol. Filtered the obtained distillation section in ultra-clean filter L101 with the
2018101890 30 Nov 2018 porous membrane filter, then subpackaged and got the finished product.
The qualities of the product are as follows:
| Exterior | Colorless transparent liquid | Refractive index | 1.364 |
| Boiling point | 79 °C | Density (20 °C) | 0.793 g/mL |
The embodiments of the present invention are merely preferred embodiments of the present invention, but the range of the present invention is not limited this, and any person who is familiar with those skilled in the arts, within the technical range of the present invention. It is intended that the technical solution and its inventive concept be replaced or modified equivalently with reference to the range of the invention.
Claims (3)
1. Pharmaceutical intermediate high purity anhydrous ethanol production plant, including: industrial furnace (B101), distillation still (E101), rectifying column (E102),
5 ultra-clean filter (L101); among them, distillation still (El01) is connected respectively to industrial furnace (B101) and rectifying column (E102), rectifying column (E102) is connected to ultra-clean filter (L101); among them, nominal volume of distillation still (El 01) is 4200-4400 L.
2. Pharmaceutical intermediate high purity anhydrous ethanol production
10 plant,according to claim 1 wherein outer pot diameter of rectifying column (El02) is
1500-1600 mm.
3. S Pharmaceutical intermediate high purity anhydrous ethanol production plant,according to claim 1 wherein microporous membrane diameter of ultra-clean filter (L101) is 1.5-1.7 pm.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2017112996360 | 2017-12-09 | ||
| CN201711299636.0A CN108238848A (en) | 2017-12-09 | 2017-12-09 | The process units of the high-pure anhydrous ethyl alcohol of medicine intermediate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2018101890A4 true AU2018101890A4 (en) | 2019-01-24 |
Family
ID=61158064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018101890A Ceased AU2018101890A4 (en) | 2017-12-09 | 2018-11-30 | Pharmaceutical intermediate high purity anhydrous ethanol production plant |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN108238848A (en) |
| AU (1) | AU2018101890A4 (en) |
| GB (2) | GB201722277D0 (en) |
-
2017
- 2017-12-09 CN CN201711299636.0A patent/CN108238848A/en not_active Withdrawn
- 2017-12-29 GB GBGB1722277.9A patent/GB201722277D0/en not_active Ceased
- 2017-12-29 GB GBGB1722223.3A patent/GB201722223D0/en not_active Ceased
-
2018
- 2018-11-30 AU AU2018101890A patent/AU2018101890A4/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| GB201722223D0 (en) | 2018-02-14 |
| GB201722277D0 (en) | 2018-02-14 |
| CN108238848A (en) | 2018-07-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103467475B (en) | The purification process of 1, 8-Cineole | |
| CN101348435A (en) | Method for preparing tributyl citrate with ion liquid as catalyst | |
| AU2018101890A4 (en) | Pharmaceutical intermediate high purity anhydrous ethanol production plant | |
| CN101830779B (en) | Method for selectively synthesizing normal borneol | |
| IE20180552U1 (en) | Pharmaceutical intermediate high purity anhydrous ethanol production plant | |
| EP2635544A1 (en) | Method for the production of a phenylcyclohexane | |
| IES20180552A2 (en) | Pharmaceutical intermediate high purity anhydrous ethanol production plant | |
| AU2018101864A4 (en) | Analgesic 2,4,6-trinitro-3,3-dimethyl-5-tert-butylbenzene production plant | |
| AU2018101841A4 (en) | Organic raw material methylated ethanol production plant | |
| AU2018101891A4 (en) | Aspirin drug intermediate high purity acetic acid production plant | |
| CN105413722B (en) | Derive the catalyst compounded of conversion production pyruvic acid for chemical catalytic oxidation lactic acid | |
| AU2018101845A4 (en) | 3,4-dioxymethylene benzaldehyde production plant | |
| KR102263109B1 (en) | Dipropylene glycol composition and preparation method thereof | |
| CN110668922A (en) | Refining method of musk medulla | |
| IE20180504U1 (en) | Organic raw material methylated ethanol production plant | |
| CN110156808A (en) | Fangchinoline-carbamate derivates with bactericidal activity | |
| CN115974669B (en) | Method for efficiently separating high-purity citronellal from eucalyptus citriodora essential oil | |
| JP6348813B2 (en) | Antibacterial and antiseptic composition containing methylbutanediol as an active ingredient, and cosmetics, pharmaceuticals or quasi drugs containing the composition | |
| AU2018101842A4 (en) | Organic raw material farnesol production plant | |
| AU2018101885A4 (en) | Pharmaceutical intermediate high purity toluene production plant | |
| CN108117487B (en) | Acetyl chloride decoloring method and application of acidic strong oxidant in acetyl chloride decoloring | |
| CN112778085A (en) | 1, 2-hexanediol and purification method and application thereof | |
| IE20180553U1 (en) | Aspirin drug intermediate high purity acetic acid production plant | |
| CN106818770B (en) | A kind of application of the formamide of azophenlyene 1 transformation compound 18 1 in Sclerotinia sclerotiorum is suppressed | |
| IE20180508U1 (en) | 3,4-dioxymethylene benzaldehyde production plant |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGI | Letters patent sealed or granted (innovation patent) | ||
| MK22 | Patent ceased section 143a(d), or expired - non payment of renewal fee or expiry |