AU2017314880B2 - Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms - Google Patents

Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms Download PDF

Info

Publication number
AU2017314880B2
AU2017314880B2 AU2017314880A AU2017314880A AU2017314880B2 AU 2017314880 B2 AU2017314880 B2 AU 2017314880B2 AU 2017314880 A AU2017314880 A AU 2017314880A AU 2017314880 A AU2017314880 A AU 2017314880A AU 2017314880 B2 AU2017314880 B2 AU 2017314880B2
Authority
AU
Australia
Prior art keywords
chelating
mahmp
polymer
compositions
raft
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2017314880A
Other languages
English (en)
Other versions
AU2017314880A1 (en
Inventor
Sazid ALI
M. Trisha C. ANG
Bruce E. Holbein
Gireesh MAHANDRU
Dnyaneshwar Vithoba PALASKAR
S. Vijaya Bhaskara REDDY
Ganugapati Satyanarayana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHELATION PARTNERS Inc
Original Assignee
CHELATION PARTNERS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHELATION PARTNERS Inc filed Critical CHELATION PARTNERS Inc
Publication of AU2017314880A1 publication Critical patent/AU2017314880A1/en
Priority to AU2021204603A priority Critical patent/AU2021204603B2/en
Application granted granted Critical
Publication of AU2017314880B2 publication Critical patent/AU2017314880B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52Amides or imides
    • C08F220/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52Amides or imides
    • C08F220/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/60Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
    • C08F226/10N-Vinyl-pyrrolidone
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2438/00Living radical polymerisation
    • C08F2438/03Use of a di- or tri-thiocarbonylthio compound, e.g. di- or tri-thioester, di- or tri-thiocarbamate, or a xanthate as chain transfer agent, e.g . Reversible Addition Fragmentation chain Transfer [RAFT] or Macromolecular Design via Interchange of Xanthates [MADIX]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polymerisation Methods In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2017314880A 2016-08-26 2017-08-25 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms Active AU2017314880B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2021204603A AU2021204603B2 (en) 2016-08-26 2021-07-01 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662380047P 2016-08-26 2016-08-26
US62/380,047 2016-08-26
PCT/CA2017/050999 WO2018035613A1 (en) 2016-08-26 2017-08-25 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2021204603A Division AU2021204603B2 (en) 2016-08-26 2021-07-01 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms

Publications (2)

Publication Number Publication Date
AU2017314880A1 AU2017314880A1 (en) 2019-04-11
AU2017314880B2 true AU2017314880B2 (en) 2021-07-29

Family

ID=61245905

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2017314880A Active AU2017314880B2 (en) 2016-08-26 2017-08-25 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms
AU2021204603A Active AU2021204603B2 (en) 2016-08-26 2021-07-01 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2021204603A Active AU2021204603B2 (en) 2016-08-26 2021-07-01 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms

Country Status (6)

Country Link
US (2) US11059785B2 (enExample)
EP (1) EP3504188A4 (enExample)
JP (1) JP7387429B2 (enExample)
AU (2) AU2017314880B2 (enExample)
CA (1) CA3034540A1 (enExample)
WO (1) WO2018035613A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11059785B2 (en) * 2016-08-26 2021-07-13 Chelation Partners Incorporated Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms
CN108276303A (zh) * 2018-03-14 2018-07-13 中国科学院青岛生物能源与过程研究所 一种含糖聚合物单体n-(2-d-葡萄糖酰胺基乙基)甲基丙烯酰胺的合成方法
WO2021094751A1 (en) * 2019-11-11 2021-05-20 Oxford University Innovation Limited Biomarkers for the prediction and identification of parkinson's disease
CN111995567B (zh) * 2020-07-24 2022-11-25 浙江工业大学 具潜在多靶点抗ad活性的甲酰胺吡啶酮类铁螯合剂衍生物及其制备方法与应用
CA3255344A1 (en) * 2022-03-24 2023-09-28 Fe Pharmaceuticals Canada Inc IRON-BINDING POLYMERIC COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT OF DISEASES ASSOCIATED WITH EXCESS HARMFUL REACTIVE IRON
JP2025537823A (ja) * 2022-11-18 2025-11-20 フィー ファーマシューティカルズ(カナダ)インコーポレイテッド 抗感染耐性を減弱させるための組成物、その使用及び方法
CN118955773B (zh) * 2024-07-31 2025-09-26 浙江大学 高聚合度的金属螯合聚合物抗体标签载体材料的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007140059A2 (en) * 2006-05-25 2007-12-06 Canadian Blood Services High molecular weight chelation structure
WO2012167368A1 (en) * 2011-06-08 2012-12-13 Chelation Partners Incorporated Metal chelating compositions and methods for controlling the growth or activities of a living cell or organism

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102066444A (zh) 2008-05-13 2011-05-18 华盛顿大学 胶束装配体
US11059785B2 (en) * 2016-08-26 2021-07-13 Chelation Partners Incorporated Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007140059A2 (en) * 2006-05-25 2007-12-06 Canadian Blood Services High molecular weight chelation structure
WO2012167368A1 (en) * 2011-06-08 2012-12-13 Chelation Partners Incorporated Metal chelating compositions and methods for controlling the growth or activities of a living cell or organism

Also Published As

Publication number Publication date
CA3034540A1 (en) 2018-03-01
EP3504188A1 (en) 2019-07-03
US20220002250A1 (en) 2022-01-06
US20190169126A1 (en) 2019-06-06
US12024490B2 (en) 2024-07-02
US11059785B2 (en) 2021-07-13
JP7387429B2 (ja) 2023-11-28
AU2017314880A1 (en) 2019-04-11
AU2021204603B2 (en) 2023-02-23
EP3504188A4 (en) 2020-04-22
JP2019526671A (ja) 2019-09-19
WO2018035613A1 (en) 2018-03-01
AU2021204603A1 (en) 2021-07-29

Similar Documents

Publication Publication Date Title
AU2021204603B2 (en) Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms
Zhang et al. The hydrolysis of cationic polycarboxybetaine esters to zwitterionic polycarboxybetaines with controlled properties
US20080234391A1 (en) Synthesis of Reversible Shell Crosslinked Nanostructures
Giaouzi et al. PNIPAM-b-PDMAEA double stimuli responsive copolymers: Effects of composition, end groups and chemical modification on solution self-assembly
Levere et al. Stable azlactone-functionalized nanoparticles prepared from thermoresponsive copolymers synthesized by RAFT polymerization
CN112375191B (zh) 嵌段共聚物及其制备方法和应用
Peng et al. Temperature and pH dual-responsive poly (vinyl lactam) copolymers functionalized with amine side groups via RAFT polymerization
Ghosh et al. Antibacterial activity of hydrophobicity modulated cationic polymers with enzyme and pH-responsiveness
Mrlik et al. Mussel-mimicking sulfobetaine-based copolymer with metal tunable gelation, self-healing and antibacterial capability
Ahmadkhani et al. Synthesis of sharply thermo and PH responsive PMA-b-PNIPAM-b-PEG-b-PNIPAM-b-PMA by RAFT radical polymerization and its schizophrenic micellization in aqueous solutions
Aquib et al. Shape matters: Effect of amphiphilic polymer topology on antibacterial activity and hemocompatibility
Rwei et al. Preparation of thermo-and pH-responsive star copolymers via ATRP and its use in drug release application
Jiang et al. Synthesis and property of chitosan graft copolymer by RAFT polymerization with tosylic acid–chitosan complex
US12257312B2 (en) Conjugates comprising a temperature-responsive polymer and a ligand capable of binding ergosterol
Maiti et al. Methionine-based carbon monoxide releasing polymer for the prevention of biofilm formation
Dutta et al. Targeting Gemcitabine hydrochloride to tumor microenvironment through stimuli-responsive Nano-conjugate: Synthesis, characterization, and in vitro assessment
Jiang et al. One-pot synthesis of pH-and thermo-sensitive chitosan-based nanoparticles by the polymerization of acrylic acid/chitosan with macro-RAFT agent
Göktaş et al. Synthesis and characterization of a brush type graft copolymer via RAFT and" click" chemistry methods
Özdemir et al. RAFT-mediated synthesis of poly (N-(2-hydroxypropyl) methacrylamide-b-4-vinylpyridine) by conventional and microwave heating
CN113825776B (zh) 在水溶液中具有上临界溶解温度的聚合物
Tong et al. Synthesis and characterization of thermo‐and pH‐sensitive block copolymers bearing a biotin group at the poly (ethylene oxide) chain end
Strelova et al. Copolymers of methyl acrylate and vinylazoles: synthesis, thermolabile properties, and grafting of polyamine chains
SOROKIN et al. Interaction of the nitrogen-containing carbon backbone polymers with essential α-amino acids
Alsughayer et al. Synthesis and characterization of polysulfanilamide and its copolymers: bioactivity and drug release
van Dijk et al. Synthesis and characterization of tailorable biodegradable thermoresponsive methacryloylamide polymers based on l-serine and l-threonine alkyl esters

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)