AU2016200921A1 - Method for better utilising the production potential of transgenic plants - Google Patents

Abstract

METHOD FOR BETTER UTILISING THE PRODUCTION POTENTIAL OF TRANSGENIC PLANTS Abstract The invention relates to a method for better utilising the production potential of transgenic plants. Said plant is treated with combinations of active substances containing an active substance from the group of anthranillic acid amids and at least one other insecticide.

Description

WO 2008/125245 PCT/EP2008/002759 Method for better utilising the production potential of transgenic plants The invention relates to a method for improving the utilization of the production potential of transgenic plants. In recent years, there has been a marked increase in the proportion of transgenic plants in 5 agriculture, even if regional differences are still noticeable to date. Thus, for example, the proportion of transgenic maize in the USA has doubled from 26% to 52% since 2001, while transgenic maize has hardly been of any practical importance in Germany. However, in other European countries, for example in Spain, the proportion of transgenic maize is already about 12%. 10 Transgenic plants are employed mainly to utilize the production potential of respective plant varieties in the most favourable manner, at the lowest possible input of production means. The aim of the genetic modification of the plants is in particular the generation of resistance in the plants to certain pests or harmful organisms or else herbicides and also to abiotic stress (for example drought, heat or elevated salt levels). It is also possible to modify a plant genetically to increase 15 certain quality or product features, such as, for example, the content of selected vitamins or oils, or to improve certain fibre properties. Herbicide resistance or tolerance can be achieved, for example, by incorporating genes into the useful plant for expressing enzymes to detoxify certain herbicides, so that a relatively unimpeded growth of these plants is possible even in the presence of these herbicides for controlling broad 20 leaved weeds and weed grasses. Examples which may be mentioned are cotton varieties or maize varieties which tolerate the herbicidally active compound glyphosate (Roundup®), (Roundup Ready, Monsanto) or the herbicides glufosinate or oxynil. More recently, there has also been the development of useful plants comprising two or more genetic modifications ("stacked transgenic plants" or multiply transgenic crops). Thus, for 25 example, Monsanto has developed multiply transgenic maize varieties which are resistant to the European corn borer (Ostrinia nubilalis) and the Western corn rootworm (Diabrotica virgifera). Also known are maize and cotton crops which are both resistant to the Western corn rootworm and the cotton bollworm and tolerant to the herbicide Roundup®. It has now been found that the utilization of the production potential of transgenic useful plants 30 can be improved even more by treating the plants with a mixture of an active compound of the formula (I) and an active compound of group II. Here, the term "treatment" includes all measures resulting in a contact between these active compounds and at least one plant part. "Plant parts" are WO 2008/125245 PCT/EP2008/002759 -2 to be understood as meaning all above-ground and below-ground parts and organs of plants, such as shoot, leaf, flower and root, by way of example leaves, needles, stalks, stems, flowers, fruit bodies, fruits and seed, and also roots, tubers and rhizomes. The plant parts also include harvested material and also vegetative and generative propagation material, for example cuttings, tubers, 5 rhizomes, slips and seed. It is already known that compounds of the formula (I) have insecticidal action (for example from WO 03/015519 and WO 04/067528), and that they can be used in mixtures (for example from WO 05/048711, WO 05/107468, WO 06/007595, WO 06/068669). These documents are expressly incorporated herein by way of reference. 10 The mixtures which can be used according to the invention comprise an active compound of the formula (I) as follows: Br 0 /N\

CH

3 N NH CI RI 0 NH

O

3 (I) where RI represents Cl or cyano 15 and at least one compound of group II, which comprises imidachloprid, thiodicarb, clothianidin, methiocarb, thiacloprid, thiamethoxam, fipronil, tefluthrin, beta-cyfluthrin, abamectin or spinosad. Preference is given to mixtures comprising the active compound of the formula (I-1) WO 2008/125245 PCT/EP2008/002759 -3 Br 0 \N O N H3 N NH N CI' O' NH 0 1

CH

3 and at least one compound of group II, which comprises imidachloprid, thiodicarb, clothianidin, methiocarb, thiacloprid, thiamethoxam, fipronil, tefluthrin, beta-cyfluthrin, abamectin or spinosad. 5 Preference is likewise given to mixtures comprising the active compound of the formula (1-2) Br O -N CH N NHN C N O NH

CH

3 (1-2) and at least one compound of group 1I, which comprises imidachloprid, thiodicarb, clothianidin, methiocarb, thiacloprid, thiamethoxam, fipronil, tefluthrin, beta-cyfluthrin, abamectin or spinosad. 10 Particular preference is given to the mixtures below comprising the active compound of the formula 1-1 and imidacloprid; the active compound of the formula 1-1 and clothianidin; the active compound of the formula 1-2 and imidacloprid; the active compound of the formula 1-2 and clothianidin. 15 In addition, the active compound combinations may also comprise further fungicidally, acaricidally or insecticidally active co-components.

WO 2008/125245 PCT/EP2008/002759 -4.

In general, the mixtures according to the invention comprise an active compound of the formula (I) and an active compound of group (II) in the stated preferred and particularly preferred mixing ratios: The preferred mixing ratio is from 250:1 to 1:50. 5 The particularly preferred mixing ratio is from 25:1 to 1:25. The mixing ratios are based on weight ratios. The ratio is to be understood as active compound of the formula (I):co-component of group (II). According to the method proposed according to the invention, transgenic plants, in particular useful plants, are treated with the mixtures according to the invention to increase agricultural 10 productivity. For the purpose of the invention, transgenic plants are plants which contain at least one "foreign gene". The term "foreign gene" in this connection means a gene or gene fragment which may originate or be derived from another plant of the same species, from plants of a different species, but also from organisms from the animal kingdom or microorganisms (including viruses) ("foreign gene") and/or, if appropriate, already has mutations compared to a naturally 15 occurring gene or gene fragment. According to the invention, it is also possible to use synthetic genes or gene fragements, which is also included in the term "foreign gene" here. It is also possible for a transgenic plant to code for two or more foreign genes of different origin. For the purpose of the invention, the "foreign gene" is further characterized in that it comprises a nucleic acid sequence which has a certain biological or chemical function or activity in the 20 transgenic plant. In general, these genes code for biocatalysts, such as, for example, enzymes or ribozymes, or else they comprise regulatory sequences, such as, for example, promoters or terminators, for controlling the expression of endogenous proteins. However, to this end, they may also code for regulatory proteins, such as, for example, repressors or inductors. Furthermore, the foreign gene may also serve the targeted localization of a gene product of the transgenic plant, 25 coding, for example, for a signal peptide. The foreign gene may also code for inhibitors, such as, for example, antisense RNA. The person skilled in the art is readily familiar with numerous different methods for producing transgenic plants and methods for the targeted mutagenesis, for gene transformation and cloning, for example from: Willmitzer, 1993, Transgenic plants, in: Biotechnology, A Multivolume 30 Comprehensive Treatise, Rehm et al. (eds.), Vol. 2, 627-659, VCH Weinheim, Germany; McCormick et al., 1986, Plant Cell Reports 5: 81-84; EP-A 0221044; EP-A 0131624, or Sambrook et al., 1989, "Molecular Cloning: A Laboratory Manual", 3rd Ed., Cold Spring Harbor Laboratory WO 2008/125245 PCT/EP2008/002759 -5 Press, Cold Spring Harbor, NY; Winnacker, 1996, "Gene und Klone" [Genes and Clones], 2nd Ed., VCH Weinheim or Christou, 1996, Trends in Plant Science 1: 423-431. Examples of transit or signal peptides or time- or site-specific promoters are disclosed, for example, in Braun et al., 1992, EMBO J. 11: 3219-3227; Wolter et al., 1988, Proc. Nati. Acad. Sci. USA 85: 846-850; Sonnewald 5 et al., 1991, Plant J. 1: 95-106. A good example of a complex genetic manipulation of a useful plant is the so-called GURT technology ("Genetic Use Restriction Technologies") which allows the technical control of the propagation of the transgenic plant variety in question. To this end, in general two or three foreign genes are cloned into the useful plant which, in a complex interaction after administration of an 10 external stimulus, trigger a cascade resulting in the death of the embryo which would otherwise develop. To this end, the external stimulus (for example an active compound or another chemical or abiotic stimulus) may interact, for example, with a repressor which then no longer suppresses the expression of a recombinase, so that the recombinase is able to cleave an inhibitor thus allowing expression of a toxin causing the embryo to die. Examples of this type of transgenic 15 plants are disclosed in US 5,723,765 or US 5,808,034. Accordingly, the person skilled in the art is familiar with processes for generating transgenic plants which, by virtue of the integration of regulatory foreign genes and the overexpression, suppression or inhibition of endogenous genes or gene sequences mediated in this manner, if appropriate, or by virtue of the existence or expression of foreign genes or fragments thereof, have modified 20 properties. As already discussed above, the method according to the invention allows better utilization of the production potential of transgenic plants. On the one hand, this may, if appropriate, be based on the fact that the application rate of the active compound which can be employed according to the invention can be reduced, for example by lowering the dose employed or else by reducing the 25 number of applications. On the other hand, if appropriate, the yield of the useful plants may be increased quantitatively and/or qualitatively. This is true in particular in the case of a transgenically generated resistance to biotic or abiotic stress. Depending on the plant species or plant varieties, their location and the growth conditions (soils, climate, vegetation period, nutrients), these synergistic actions may vary and may be multifarious. 30 Thus possible are, for example, reduced application rates and/or a widening of the activity spectrum and/or an increase of the activity of the compounds and compositions used according to the invention, better plant growth, increased tolerance to high or low temperatures, increased tolerance to drought or to water or soil salt content, increased flowering, easier harvesting, accelerated maturation, higher harvest yields, higher quality and/or higher nutrient value of the WO 2008/125245 PCT/EP2008/002759 -6 harvested products, increased storability and/or processibility of the harvested products, which exceed the effects normally to be expected. These advantages are the result of a synergistic action, achieved according to the invention, between the mixtures according to the invention which can be employed and the respective 5 principle of action of the genetic modification of the transgenic plant. This reduction of production means as a result of the synergism, with simultaneous yield or quality increase, is associated with considerable economical and ecological advantages. A list of examples known to the person skilled in the art of transgenic plants, with the respective affected structure in the plant or the protein expressed by the genetic modification in the plant 10 being mentioned, is compiled in Table 1. Here, the structure in question or the principle expressed is in each case grouped with a certain feature in the sense of a tolerance to a certain stress factor. A similar list (Table 3) compiles - in a slightly different arrangement - likewise examples of principles of action, tolerances induced thereby and possible useful plants. Further examples of transgenic plants suitable for the treatment according to the invention are compiled in Table 4. 15 In an advantageous embodiment, the mixtures according to the invention are used for treating transgenic plants comprising at least one foreign gene coding for a Bt toxin. A Bt toxin is a protein originating from or derived from the soil bacterium Bacillus thuringiensis which either belongs to the group of the crystal toxins (Cry) or the cytolytic toxins (Cyt). In the bacterium, they are originally formed as protoxins and are only metabolized in alkaline medium - for example in the 20 digestive tract of certain feed insects - to their active form. There, the active toxin then binds to certain hydrocarbon structures at cell surfaces causing pores to be formed which destroy the osmotic potential of the cell, which may effect cell lysis. The result is the death of the insects. Bt toxins are active in particular against certain harmful species from the orders of the Lepidoptera (butterflies), Homoptera, Diptera and Coleoptera (beetles) in all their development stages; i.e. from 25 the egg larva via their juvenile forms to their adult forms. It has been known for a long time that gene sequences coding for Bt toxins, parts thereof or else peptides or proteins derived from Bt toxins can be cloned with the aid of genetic engineering into agriculturally useful plants to generate transgenic plants having endogenous resistance to pests sensitive to Bt toxins. For the purpose of the invention, the transgenic plants coding for at least one 30 Bt toxin or proteins derived therefrom are defined as "Bt plants". The "first generation" of such Bt plants generally only comprise the genes enabling the formation of a certain toxin, thus only providing resistance to one group of pathogens. An example of a commercially available maize variety comprising the gene for forming the CrylAb toxin is WO 2008/125245 PCT/EP2008/002759 -7 "YieldGard@" from Monsanto which is resistant to the European corn borer. In contrast, in the Bt cotton variety (Bollgard@), resistance to other pathogens from the family of the Lepidoptera is generated by introduction by cloning of the genes for forming the CrylAc toxin. Other transgenic crop plants, in turn, express genes for forming Bt toxins with activity against pathogens from the 5 order of the Coleoptera. Examples that may be mentioned are the Bt potato variety "NewLeaf@" (Monsanto) capable of forming the Cry3A toxin, which is thus resistant to the Colorado potato beetle, and the transgenic maize variety "YieldGard@" (Monsanto) which is capable of forming the Cry 3Bbl toxin and is thus protected against various species of the Western corn rootworm. In a "second generation", the multiply transgenic plants, already described above, expressing or 10 comprising at least two foreign genes were generated. Preference according to the invention is given to transgenic plants with Bt toxins from the group of the Cty family (see, for example, Crickmore et al., 1998, Microbiol. Mol. Biol. Rev. 62 : 807-812), which are particularly effective against Lepidoptera, Coleoptera and Diptera. Examples of genes coding for the proteins are: 15 cry IAal, crylAa2, crylAa3, cry1Aa4, crylAa5, crylAa6, crylAa7, crylAa8, crylAa9, cry1Aa10, crylAall crylAbl, crylAb2, crylAb3, crylAb4, crylAb5, crylAb6, crylAb7, crylAb8, crylAb9, crylAblO, crylAbl1, crylAbl2, crylAbl3, crylAbl4, crylAcl, crylAc2, crylAc3, crylAc4, crylAc5, crylAc6, crylAc7, crylAc8, crylAc9, crylAc1O, crylAcll, crylAcl2, crylAc13, crylAdl, crylAd2, crylAel, crylAfl, crylAgl, crylBal, crylBa2, crylBbl, crylBcl, 20 crylBdl, crylBel, crylCal, crylCa2, crylCa3, crylCa4, crylCa5, crylCa6, crylCa7, crylCbl, crylCb2, crylDal, crylDa2, crylDbl, crylEal, crylEa2, crylEa3, crylEa4, crylEa5, crylEa6, crylEbl, crylFal, crylFa2, crylFbl, crylFb2, crylFb3, crylFb4, crylGal, crylGa2, crylGbl, crylGb2, crylHal, crylHbl, cryllal, crylla2, crylla3, crylla4, crylla5, crylla6, crylIbl, cryllcl, crylldl, cryllel, cryll-like, crylJal, crylJbl, crylJcl, crylKal, cryl-like, cry2Aal, 25 cry2Aa2, cry2Aa3, cry2Aa4, cry2Aa5, cry2Aa6, cry2Aa7, cry2Aa8, cry2Aa9, cry2Abl, cry2Ab2, cry2Ab3, cry2Acl, cry2Ac2, cry2Adl, cry3Aal, cry3Aa2, cry3Aa3, cry3Aa4, cry3Aa5, cry3Aa6, cry3Aa7, cry3Bal, cry3Ba2, cry3Bbl, cry3Bb2, cry3Bb3, cry3Cal, cry4Aal, cry4Aa2, cry4Bal, cry4Ba2, cry4Ba3, cry4Ba4, cry5Aal, cry5Abl, cry5Acl, cry5Bal, cry6Aal, cry6Bal, cry7Aal, cry7Abl, cry7Ab2, cry8Aal, cry8Bal, cry8Cal, cry9Aal, cry9Aa2, cry9Bal, cry9Cal, cry9Dal, 30 cry9Da2, cry9Eal, cry 9 like, crylOAal, cryl0Aa2, cryllAal, cryllAa2, cryllBal, cryllBbl, cry12Aal, cryl3Aal, cryl4Aal, cryl5Aal, cryl6Aal, cryl7Aal, cryl8Aal, cryl8Bal, cryl8Cal, cryI9Aal, cry19Bal, cry20Aal, cry21Aal, cry21Aa2, cry22Aal, cry23Aal, cry24Aal, cry25Aal, cry26Aal, cry27Aal, cry28Aal, cry28Aa2, cry29Aal, cry30Aal, cry3lAal, cytlAal, cytlAa2, cytlAa3, cytlAa4, cytlAbl, cytlBal, cyt2Aal, cyt2Bal, cyt2Ba2, cyt2Ba3, cyt2Ba4, cyt2Ba5, WO 2008/125245 PCT/EP2008/002759 -8 cyt2Ba6, cyt2Ba7, cyt2Ba8, cyt2Bbl. Particular preference is given to the genes or gene sections of the subfamilies cryl, cry2, cry3, cry5 and cry9; especially preferred are cry 1Ab, cry IAc, cry3A, cry3B and cry9C. Furthermore, it is preferred to use plants which, in addition to the genes for one or more Bt toxins, 5 express or contain, if appropriate, also genes for expressing, for example, a protease or peptidase inhibitor (such as in WO-A 95/3503 1), of herbicide resistances (for example to glufosinate or glyphosate by expression of the pat gene or bar gene) or for becoming resistant to nematodes, fungi or viruses (for example by expressing a gluconase, chitinase). However, they may also be modified in their metabolic properties, so that they show a qualitative and/or quantitative change 10 of ingredients (for example by modification of the energy, carbohydrate, fatty acid or nitrogen metabolism or by metabolite currents influencing these (see above). A list of examples of principles of action which can be introduced by genetic modification into a useful plant and which are suitable for the treatment according to the invention on their own or in combination is compiled in Table 2. Under the header "AP" (active principle), this table contains 15 the respective principle of action and associated therewith the pest to be controlled. In a particularly preferred variant, the process according to the invention is used for treating transgenic vegetable, maize, soya bean, cotton, tobacco, rice, potato and sugar beet varieties. These are preferably Bt plants. The vegetable plants or varieties are, for example, the following useful plants: 20 o potatoes: preferably starch potatoes, sweet potatoes and table potatoes; o root vegetables: preferably carrots, turnips (swedes, stubble turnips (Brassica rapa var. rapa), spring turnips, autumn turnips (Brassica campestris ssp. rapifera), Brassica rapa L. ssp. rapa f. teltowiensis), scorzonera, Jerusalem artichoke, turnip-rooted parsley, parsnip, radish and horseradish; 25 o tuber vegetables: preferably kohlrabi, beetroot, celeriac, garden radish; o bulb crops: preferably scallion, leek and onions (planting onions and seed onions); o brassica vegetables: preferably headed cabbage (white cabbage, red cabbage, kale, savoy cabbage), cauliflowers, broccoli, curly kale, marrow-stem kale, seakale and Brussels sprouts; WO 2008/125245 PCT/EP2008/002759 -9 o fruiting vegetables: preferably tomatoes (outdoor tomatoes, vine-ripened tomatoes, beef tomatoes, greenhouse tomatoes, cocktail tomatoes, industrial and fresh market tomatoes), melons, eggplants, aubergines, pepper (sweet pepper and hot pepper, Spanish pepper), chilli pepper, pumpkins, courgettes and cucumbers (outdoor cucumbers, greenhouse cucumbers 5 snake gourds and gherkins); o vegetable pulses: preferably bush beans (as sword beans, string beans, flageolet beans, wax beans, corn beans of green- and yellow-podded cultivars), pole beans (as sword beans, string beans, flageolet beans, wax beans of green-, blue- and yellow-podded cultivars), broadbeans (field beans, Windsor beans, cultivars having white- and black-spotted flowers), peas 10 (chickling vetch, chickpeas, marrow peas, shelling peas, sugar-peas, smooth peas, cultivars having light- and dark-green fresh fruits) and lentils; o green vegetables and stem vegetables: preferably Chinese cabbage, round-headed garden lettuce, curled lettuce, lamb's-lettuce, iceberg lettuce, romaine lettuce, oakleaf lettuce, endives, radicchio, lollo rossa, ruccola lettuce, chicory, spinach, chard (leaf chard and stem 15 chard) and parsley; o other vegetables: preferably asparagus, rhubarb, chives, artichokes, mint varieties, sunflowers, Florence fennel, dill, garden cress, mustard, poppy seed, peanuts, sesame und salad chicory. Bt vegetables including exemplary methods for preparing them are described in detail, for 20 example, in Barton et al., 1987, Plant Physiol. 85: 1103-1109 ; Vaeck et al., 1987, Nature 328 : 33-37 ; Fischhoff et al., 1987, Bio/Technology 5: 807-813. In addition, Bt vegetable plants are already known as commercial varieties, for example the potato cultivar NewLeaf® (Monsanto). The preparation of Bt vegetables is also described in US 6,072,105. Likewise, Bt cotton is already known in principle, for example from US-A-5,322,938 or from 25 Prietro-Samson6r et al., J. Ind. Microbiol. & Biotechn. 1997, 19, 202, and H. Agaisse and D. Lereclus, J. Bacteriol. 1996, 177, 6027. Different varieties of Bt cotton, too, are already commercially available, for example under the name NuCOTN@ (Deltapine (USA)). In the context of the present invention, particular preference is given to Bt cotton NuCOTN33@ and NuCOTN33B®. 30 The use and preparation of Bt maize has likewise already been known for a long time, for example from Ishida, Y., Saito, H., Ohta, S., Hiei, Y., Komari, T., and Kumashiro, T. (1996). High efficiency transformation of maize (Zea mayz L.) mediated by Agrobacterium tumefaciens. Nature WO 2008/125245 PCT/EP2008/002759 -10 Biotechnology 4: 745-750. EP-B-0485506, too, describes the preparation of Bt maize plants. Furthermore, different varieties of Bt maize are commercially available, for example under the following names (company/companies is/are in each case given in brackets): KnockOut® (Novartis Seeds), NaturGard@ (Mycogen Seeds), Yieldgard® (Novartis Seeds, Monsanto, Cargill, 5 Golden Harvest, Pioneer, DeKalb inter alia), Bt-Xtra® (DeKalb) and StarLink® (Aventis CropScience, Garst inter alia). For the purpose of the present invention, particular preference is given especially to the following maize cultivars: KnockOut®, NaturGard®, Yieldgard@, Bt Xtra® and StarLink®. For soya beans, too, Roundup®Ready cultivar or cultivars resistant to the herbicide Liberty Link® 10 are available and can be treated according to the invention. In the case of rice, a large number of "Golden Rice" lines are available which are likewise characterized in that, by virtue of a transgenic modification, they have an increased content of provitamin A. They, too, are examples of plants which can be treated by the method according to the invention, with the advantages described. The method according to the invention is suitable for controlling a large number of harmful 15 organisms which occur in particular in vegetables, maize and cotton, preferably arthropods and nematodes, in particular insects and arachnids. The pests mentioned include: From the order of the Isopoda, for example, Oniscus asellus, Armadillidium vulgare, Porcellio scaber. From the order of the Diplopoda, for example, Blaniulus guttulatus. 20 From the order of the Chilopoda, for example, Geophilus carpophagus, Scutigera spp. From the order of the Symphyla, for example, Scutigerella immaculata. From the order of the Thysanura, for example, Lepisma saccharina. From the order of the Collembola, for example, Onychiurus armatus. From the order of the Orthoptera, for example, Acheta domesticus, Gryllotalpa spp., Locusta 25 migratoria migratorioides, Melanoplus spp., Schistocerca gregaria. From the order of the Blattaria, for example, Blatta orientalis, Periplaneta americana, Leucophaea maderae, Blattella germanica. From the order of the Dermaptera, for example, Forficula auricularia. From the order of the Isoptera, for example, Reticulitermes spp.

WO 2008/125245 PCT/EP2008/002759 From the order of the Phthiraptera, for example, Pediculus humanus corporis, Haematopinus spp., Linognathus spp., Trichodectes spp., Damalinia spp. From the order of the Thysanoptera, for example, Hercinothrips femoralis, Thrips tabaci, Thrips palmi, Frankliniella occidentalis. 5 From the order of the Heteroptera, for example, Eurygaster spp., Dysdercus intermedius, Piesma quadrata, Cimex lectularius, Rhodnius prolixus, Triatoma spp. From the order of the Homoptera, for example, Aleurodes brassicae, Bemisia tabaci, Trialeurodes vaporariorum, Aphis gossypii, Brevicoryne brassicae, Cryptomyzus ribis, Aphis fabae, Aphis pomi, Eriosoma lanigerum, Hyalopterus arundinis, Phylloxera vastatrix, Pemphigus spp., 10 Macrosiphum avenae, Myzus spp., Phorodon humuli, Rhopalosiphum padi, Empoasca spp., Euscelis bilobatus, Nephotettix cincticeps, Lecanium comi, Saissetia oleae, Laodelphax striatellus, Nilaparvata lugens, Aonidiella aurantii, Aspidiotus hederae, Pseudococcus spp., Psylla spp. From the order of the Lepidoptera, for example, Pectinophora gossypiella, Bupalus piniarius, Cheimatobia brumata, Lithocolletis blancardella, Hyponomeuta padella, Plutella xylostella, 15 Malacosoma neustria, Euproctis chrysorrhoea, Lymantria spp., Bucculatrix thurberiella, Phyllocnistis citrella, Agrotis spp., Euxoa spp., Feltia spp., Earias insulana, Heliothis spp., Mamestra brassicae, Panolis flammea, Spodoptera spp., Trichoplusia ni, Carpocapsa pomonella, Pieris spp., Chilo spp., Pyrausta nubilalis, Ephestia kuehniella, Galleria mellonella, Tineola bisselliella, Tinea pellionella, Hofmannophila pseudospretella, Cacoecia podana, Capua reticulana, 20 Choristoneura fumiferana, Clysia ambiguella, Homona magnanima, Tortrix viridana, Cnaphalocerus spp., Oulema oryzae. From the order of the Coleoptera, for example, Anobium punctatum, Rhizopertha dominica, Bruchidius obtectus, Acanthoscelides obtectus, Hylotrupes bajulus, Agelastica alni, Leptinotarsa decemlineata, Phaedon cochleariae, Diabrotica spp., Psylliodes chrysocephala, Epilachna 25 varivestis, Atomaria spp., Oryzaephilus surinamensis, Anthonomus spp., Sitophilus spp., Otiorrhynchus sulcatus, Cosmopolites sordidus, Ceuthorrhynchus assimilis, Hypera postica, Dermestes spp., Trogoderma spp., Anthrenus spp., Attagenus spp., Lyctus spp., Meligethes aeneus, Ptinus spp., Niptus hololeucus, Gibbium psylloides, Tribolium spp., Tenebrio molitor, Agriotes spp., Conoderus spp., Melolontha melolontha, Amphimallon solstitialis, Costelytra zealandica, 30 Lissorhoptrus oryzophilus. From the order of the Hymenoptera, for example, Diprion spp., Hoplocampa spp., Lasius spp., Monomorium pharaonis, Vespa spp.

WO 2008/125245 PCT/EP2008/002759 - 12 From the order of the Diptera, for example, Aedes spp., Anopheles spp., Culex spp., Drosophila melanogaster, Musca spp., Fannia spp., Calliphora erythrocephala, Lucilia spp., Chrysomyia spp., Cuterebra spp., Gastrophilus spp., Hyppobosca spp., Stomoxys spp., Oestrus spp., Hypoderma spp., Tabanus spp., Tannia spp., Bibio hortulanus, Oscinella frit, Phorbia spp., Pegomyia 5 hyoscyami, Ceratitis capitata, Dacus oleae, Tipula paludosa, Hylemyia spp., Liriomyza spp. From the order of the Siphonaptera, for example, Xenopsylla cheopis, Ceratophyllus spp. From the class of the Arachnida, for example, Scorpio maurus, Latrodectus mactans, Acarus siro, Argas spp., Ornithodoros spp., Dermanyssus gallinae, Eriophyes ribis, Phyllocoptruta oleivora, Boophilus spp., Rhipicephalus spp., Amblyomma spp., Hyalomma spp., Ixodes spp., Psoroptes 10 spp., Chorioptes spp., Sarcoptes spp., Tarsonemus spp., Bryobia praetiosa, Panonychus spp., Tetranychus spp., Hemitarsonemus spp., Brevipalpus spp. The plant-parasitic nematodes include, for example, Pratylenchus spp., Radopholus similis, Ditylenchus dipsaci, Tylenchulus semipenetrans, Heterodera spp., Globodera spp., Meloidogyne spp., Aphelenchoides spp., Longidorus spp., Xiphinema spp., Trichodorus spp., Bursaphelenchus 15 spp. The method according to the invention is particularly suitable for treating sugar beet or Bt vegetables, Bt maize, Bt cotton, Bt soya beans, Bt tobacco and also Bt rice or Bt potatoes for controlling insects from the order of the Isoptera, for example, Reticulitermes spp., from the order of the Thysanoptera, for example, Thrips tabaci, Thrips palm, Frankliniella occidentalis, from the 20 order of the Heteroptera, for example, Eurygaster spp., Dysdercus intermedius, Piesma quadrata, from the order of the Homoptera, for example, Aleurodes brassicae, Bemisia tabaci, Trialeurodes vaporariorum, Aphis gossypii, Brevicoryne brassicae, Cryptomyzus ribis, Aphis fabae, Aphis pomi, Eriosoma lanigerum, Phylloxera vastatrix, Pemphigus spp., Macrosiphum avenae, Myzus spp., Phorodon humuli, Rhopalosiphum padi, Empoasca spp., Nephotettix cincticeps, Lecanium 25 corni, Saissetia oleae, Laodelphax striatellus, Nilaparvata lugens, Aonidiella aurantii, Pseudococcus spp., Psylla spp., from the order of the Lepidoptera, for example, Pectinophora gossypiella, Cheimatobia brumata, Lithocolletis blancardella, Hyponomeuta padella, Plutella xylostella, Euproctis chrysorrhoea, Lymantria spp., Phyllocnistis citrella, Agrotis spp., Earias insulana, Heliothis spp., Mamestra brassicae, Spodoptera spp., Trichoplusia ni, Carpocapsa 30 pomonella, Pieris spp., Chilo spp., Pyrausta nubilalis, Ephestia kuehniella, Capua reticulana, Clysia ambiguella, Tortrix viridana, Cnaphalocerus spp., Oulema oryzae, from the order of the Coleoptera, for example, Leptinotarsa decemlineata, Phaedon cochleariae, Diabrotica spp., Psylliodes chrysocephala, Epilachna varivestis, Atomaria spp., Oryzaephilus surinamensis, Antho nomus spp., Sitophilus spp., Otiorrhynchus sulcatus, Cosmopolites sordidus, Ceuthorrhynchus WO 2008/125245 PCT/EP2008/002759 -13 assimilis, Meligethes aeneus, Tribolium spp., Tenebrio molitor, Agriotes spp., Lissorhoptrus oryzophilus, from the order of the Hymenoptera, for example, Diprion spp., Hoplocampa spp. or from the order of the Diptera, for example, Oscinella frit, Phorbia spp., Pegomyia hyoscyami, Ceratitis capitata, Dacus oleae, Hylemyia spp., Liriomyza spp. 5 The active compound combinations can be employed in customary formulations, such as solutions, emulsions, wettable powders, water- and oil-based suspensions, powders, dusts, pastes, soluble powders, soluble granules, granules for broadcasting, suspoemulsion concentrates, natural compounds impregnated with active compound, synthetic substances impregnated with active compound, fertilizers and also microencapsulations in polymeric substances. 10 These formulations are prepared in a known manner, for example by mixing the active compounds with extenders, i.e. liquid solvents and/or solid carriers, if appropriate using surfactants, i.e. emulsifiers and/or dispersants and/or foam-formers. The formulations are prepared either in suitable plants or else before or during application. Wettable powders are preparations which can be dispersed homogeneously in water and which, in 15 addition to the active compound and beside a diluent or inert substance, also comprise wetting agents, for example polyethoxylated alkylphenols, polyethoxylated fatty alcohols, alkylsulphonates or alkylphenylsulphonates and dispersants, for example sodium lignosulphonate, sodium 2,2' dinaphthylmethane-6,6'-disulphonate. Dusts are obtained by grinding the active compound with finely distributed solid substances, for 20 example talc, natural clays, such as kaolin, bentonite, pyrophillite or diatomaceous earth. Granules can be prepared either by spraying the active compound onto granular inert material capable of adsorption or by applying active compound concentrates to the surface of carrier substances, such as sand, kaolinites or granular inert material, by means of adhesives, for example polyvinyl alcohol, sodium polyacrylate or mineral oils. Suitable active compounds can also be granulated in 25 the manner customary for the preparation of fertilizer granules - if desired as a mixture with fertilizers. Suitable for use as auxiliaries are substances which are suitable for imparting to the composition itself and/or to preparations derived therefrom (for example spray liquors, seed dressings) particular properties such as certain technical properties and/or also particular biological 30 properties. Typical suitable auxiliaries are: extenders, solvents and carriers. Suitable extenders are, for example, water, polar and nonpolar organic chemical liquids, for example from the classes of the aromatic and non-aromatic hydrocarbons (such as paraffins, WO 2008/125245 PCT/EP2008/002759 -14 alkylbenzenes, alkylnaphthalenes, chlorobenzenes), the alcohols and polyols (which, if appropriate, may also be substituted, etherified and/or esterified), the ketones (such as acetone, cyclohexanone), esters (including fats and oils) and (poly)ethers, the unsubstituted and substituted amines, amides, lactams (such as N-alkylpyrrolidones) and lactones, the sulphones and 5 sulphoxides (such as dimethyl sulphoxide). If the extender used is water, it is also possible to employ, for example, organic solvents as auxiliary solvents. Essentially, suitable liquid solvents are: aromatics such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics and chlorinated aliphatic hydrocarbons such as chlorobenzenes, chloroethylenes or methylene chloride, aliphatic hydrocarbons such as cyclohexane 10 or paraffins, for example petroleum fractions, mineral and vegetable oils, alcohols such as butanol or glycol and also their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents such as dimethyl sulphoxide, and also water. Example of suitable solid carriers are: for example, ammonium salts and ground natural minerals such as kaolins, clays, talc, chalk, quartz, 15 attapulgite, montmorillonite or diatomaceous earth, and ground synthetic minerals, such as finely divided silica, alumina and silicates; suitable solid carriers for granules are: for example, crushed and fractionated natural rocks such as calcite, marble, pumice, sepiolite and dolomite, and also synthetic granules of inorganic and organic meals, and granules of organic material such as paper, sawdust, coconut shells, maize cobs and tobacco stalks; suitable emulsifiers and/or foam-formers are: for 20 example, nonionic and anionic emulsifiers, such as polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers, for example alkylaryl polyglycol ethers, alkylsulphonates, alkyl sulphates, arylsulphonates and also protein hydrolysates; suitable dispersants are nonionic and/or ionic substances, for example from the classes of the alcohol-POE and/or -POP ethers, acid and/or POP POE esters, alkylaryl and/or POP POE ethers, fat and/or POP POE adducts, POE- and/or 25 POP-polyol derivatives, POE- and/or POP-sorbitan or -sugar adducts, alkyl or aryl sulphates, alkyl or arylsulphonates and alkyl or aryl phosphates or the corresponding PO-ether adducts. Furthermore, suitable oligo- or polymers, for example those derived from vinylic monomers, from acrylic acid, from EO and/or PO alone or in combination with, for example, (poly)alcohols or (poly)amines. It is also possible to employ lignin and its sulphonic acid derivatives, unmodified 30 and modified celluloses, aromatic and/or aliphatic sulphonic acids and their adducts with formaldehyde. Tackifiers such as carboxymethylcellulose and natural and synthetic polymers in the form of powders, granules or latices, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, as well as natural phospholipids such as cephalins and lecithins, and synthetic phospholipids, can be used in the WO 2008/125245 PCT/EP2008/002759 - 15 formulations. It is possible to use colorants such as inorganic pigments, for example iron oxide, titanium oxide and Prussian Blue, and organic dyestuffs, such as alizarin dyestuffs, azo dyestuffs and metal phthalocyanine dyestuffs, and trace nutrients such as salts of iron, manganese, boron, copper, cobalt, 5 molybdenum and zinc. Other possible additives are perfumes, mineral or vegetable, optionally modified oils, waxes and nutrients (including trace nutrients), such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc. Stabilizers, such as low-temperature stabilizers, preservatives, antioxidants, light stabilizers or 10 other agents which improve chemical and/or physical stability may also be present. These individual types of formulation are known in principle and are described, for example, in: Winnacker-Kiichler, 1986, "Chemische Technologie" [Chemical Technology], Volume 7, 4th Ed., C. Hauser Verlag Munich; van Falkenberg, 1972-73, "Pesticides Formulations", 2nd Ed., Marcel Dekker N.Y.; Martens, 1979, "Spray Drying Handbook", 3rd Ed., G. Goodwin Ltd. London. 15 Based on his general expert knowledge, the person skilled in the art is able to choose suitable formulation auxiliaries (in this context, see, for example, Watkins, "Handbook of Insecticide Dust Diluents and Carriers", 2nd Ed., Darland Books, Caldwell N.J.; v. Olphen, "Introduction to Clay Colloid Chemistry", 2nd Ed., J. Wiley & Sons, N.Y.; Marsden, "Solvents Guide", 2nd Ed., Interscience, N.Y. 1950; McCutcheon's, "Detergents and Emulsifiers Annual", MC Publ. Corp., 20 Ridgewood, N.J.; Sisley and Wood, "Encyclopedia of Surface Active Agents", Chem. Publ. Co. Inc., N.Y. 1964; Schdnfeldt, "Grenzflichenaktive Athylenoxidaddukte" [Surface-active Ethylene Oxide Adducts], Wiss. Verlagsgesell., Stuttgart 1967; Winnacker-Kichler, "Chemische Technologie" [Chemical Technology], Volume 7,4th Ed., C. Hanser Verlag Munich 1986. The active compound combinations according to the invention, in commercially available 25 formulations and in the use forms prepared from these formulations, can be present in a mixture with other known active compounds such as insecticides, attractants, sterilants, bactericides, acaricides, nematicides, fungicides, growth regulators or herbicides. The insecticides include, for example, phosphoric esters, carbamates, carboxylic esters, chlorinated hydrocarbons, phenylureas, substances produced by microorganisms, and the like. 30 A mixture with other known active compounds such as herbicides, or with fertilizers and growth regulators, is also possible.

WO 2008/125245 PCT/EP2008/002759 -16 When used as insecticides, the active compound combinations according to the invention in their commercially available formulations and in the use forms which are prepared from these formulations may furthermore be present as a mixture with synergists. Synergists are compounds by which the action of the active compounds is increased without it being necessary for the 5 synergist added to be active itself. In general, the formulations comprise from 0,01 to 98% by weight of active compound, preferably from 0.5 to 90%. In wettable powders, the active compound concentration is, for example, from about 10 to 90% by weight, the remainder to 100% by weight consisting of customary formulation components. In the case of emulsifiable concentrates, the active compound concentration can be 10 from about 5 to 80% by weight. In most cases, formulations in the form of dusts comprise from 5 to 20% by weight of active compound, sprayable solutions comprise about 2 to 20% by weight. In the case of granules, the active compound content depends partially on whether the active compound is present in liquid or solid form and on which granulation auxiliaries, fillers, etc., are used. 15 The required application rate may also vary with external conditions such as, inter alia, temperature and humidity. It may vary within wide limits, for example between 0. 1 g/h and 5.0 kg/ha or more of active substance. Owing to the synergistic effects between Bt vegetables and the active compound combinations according to the invention, particular preference is given to application rates of from 0. 1 to 500 g/ha. Particular preference is given to application rates of from 20 10 to 500 g/ha, especially preferred are 10 to 200 g/ha. In their commercial formulations and in the use forms prepared from these formulations, the mixtures according to the invention may be present as mixtures with other active compounds, such as insecticides, attractants, sterilants, acaricides, nematicides, fungicides, growth-regulating substances or herbicides. 25 The active compound content of the use forms prepared from the commercial formulations may vary within wide limits. The active compound concentration of the use forms may be from 0.0000001 to 95% by weight of active compound and is, preferably between 0.0001 and 1% by weight.

WO 2008/125245 PCT/EP2008/002759 -17 Table 1: Plant: Maize Structure affected or principle expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolepyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acid, cyclohexanedione hydroxyphenylpyruvate dioxygenase (HPPD) isooxazoles, such as isoxaflutol or isoxachlortol, triones, such as mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin O-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles, such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazole, pyridine derivative, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUI xenobiotics and herbicides, such as sulphonylurea dimboa biosynthesis (Bxl-Gen) Helminthosporium turcicum, Rhopalosiphum maydis, Diplodia maydis, Ostrinia nubilalis, Lepidoptera sp. CMIII (small basic peptide building block plant pathogens e.g. Fusarium, Altemaria, from maize grain) Sclerotina Com-SAFP (zeamatin) plant pathogens, e.g. Fusarium, Alternaria, Sclerotina, Rhizoctonia, Chaetomium, Phycomycen Hml-gene Cochliobulus WO 2008/125245 PCT/EP2008/002759 - 18 Structure affected or principle expressed Feature of the plant / tolerance to chitinases plant pathogens glucanases plant pathogens envelope proteins viruses, such as the Maize dwarf mosaic virus (MDMV) toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, Coleoptera, Diptera, Bacillus cereus toxin, Photorabdus and nematodes, e.g. Ostrinia nubilalis, Xenorhabdus toxins Heliothis zea, armyworms e.g. Spodoptera frugiperda, Western corn rootworm, Sesamia sp., Aprotis ipsilon, Asian corn borer, weevils 3-hydroxysteroid oxidase Lepidoptera, Coleoptera, Diptera, nematodes, e.g. Ostrinia nubilalis, Heliothis zea, armyworms e.g. Spodoptera frugiperda, Western corn rootworm, Sesamia sp., Aprotis ipsilon, Asian corn borer, weevils peroxidase Lepidoptera, Coleoptera, Diptera, nematodes, e.g. Ostrinia nubilalis, Heliothis zea, armyworms e.g. Spodoptera frugiperda, Western corn rootworm, Sesamia sp., Aprotis ipsilon, Asian corn borer, weevils aminopeptidase inhibitors, e.g. leucine Lepidoptera, Coleoptera, Diptera, aminopeptidase inhibitors (LAPI) nematodes, e.g. Ostrinia nubilalis, Heliothis zea, armyworms e.g. Spodoptera frugiperda, Western corn rootworm, Sesamia sp., Aprotis ipsilon, Asian corn borer, weevils limonene synthase Western corn rootworm lectin Lepidoptera, Coleoptera, Diptera, nematodes, e.g. Ostrinia nubilalis, Heliothis zea, armyworms e.g. Spodoptera frugiperda, Western corn rootworm, Sesamia sp., Aprotis ipsilon, Asian corn borer, weevils protease inhibitors e.g. cystatin, patatin, weevils, Western corn rootworm virgiferin, CPTI ribosome-inactivating protein Lepidoptera, Coleoptera, Diptera, nematodes, e.g. Ostrinia nubilalis, Heliothis zea, WO 2008/125245 PCT/EP2008/002759 -19 Structure affected or principle expressed Feature of the plant / tolerance to armyworms e.g. Spodoptera frugiperda, Western corn rootworm, Sesamia sp., Aprotis ipsilon, Asian corn borer, weevils 5C9-maize polypeptide Lepidoptera, Coleoptera, Diptera, nematodes, e.g. Ostrinia nubilalis, Heliothis zea, armywormus e.g. Spodoptera frugiperda, Western corn rootworm, Sesamia sp., Aprotis ipsilon, Asian corn borer, weevils HMG-CoA reductase Lepidoptera, Coleoptera, Diptera, nematodes, e.g. Ostrinia nubilalis, Heliothis zea, armyworms e.g. Spodoptera frugiperda, Western corn rootworm, Sesamia sp., Aprotis ipsilon, Asian corn borer, weevils Plant: Wheat Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolepyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acid, cyclohexanedione hydroxyphenylpyruvate dioxygenase (HPPD) isooxazoles, such as isoxaflutol or isoxachlortol, triones, such as mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles, such as brornoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) WO 2008/125245 PCT/EP2008/002759 - 20 Structure affected / protein expressed Feature of the plant / tolerance to glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUI xenobiotics and herbicides, such as sulphonylurea compounds antifungal polypeptide AlyAFP plant pathogens, e.g. Septoria and Fusarium glucose oxidase plant pathogens, e.g. Fusarium, Septoria pyrrolnitrin synthesis gene plant pathogens, e.g. Fusarium, Septoria serine/threonine kinases plant pathogens, e.g. Fusarium, Septoria and other diseases polypeptide having the effect of triggering plant pathogens, e.g. Fusarium, Septoria and a hypersensitivity reaction other diseases systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases plant pathogens glucanases plant pathogens double-strand ribonuclease viruses such as, for example, BYDV and MSMV envelope proteins viruses such as, for example, BYDV and MSMV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, Coleoptera, Diptera, Bacillus cereus toxins, Photorabdus and nematodes Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, Coleoptera, Diptera, nematodes peroxidase Lepidoptera, Coleoptera, Diptera, nematodes aminopeptidase inhibitors, e.g. leucine Lepidoptera, Coleoptera, Diptera, aminopeptidase inhibitor nematodes lectins Lepidoptera, Coleoptera, Diptera, nematodes, aphids protease inhibitors, e.g. cystatin, patatin, Lepidoptera, Coleoptera, Diptera, virgiferin, CPTI nematodes, aphids ribosome-inactivating protein Lepidoptera, Coleoptera, Diptera, nematodes, aphids WO 2008/125245 PCT/EP2008/002759 -21 Structure affected / protein expressed Feature of the plant / tolerance to HMG-CoA reductase Lepidoptera, Coleoptera, Diptera, nematodes, e.g. Ostrinia nubilalis, Heliothis zea, armyworms e.g. Spodoptera frugiperda, Western corn rootworm, Sesamia sp., Aprotis ipsilon, Asian corn borer, weevils Plant: Barley Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolepyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isooxazoles, such as isoxaflutol or isoxachlortol, triones, such as mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles, such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUl xenobiotics and herbicides, such as sulphonylurea compounds antifungal polypeptide AlyAFP plant pathogens, e.g. Septoria and Fusarium glucose oxidase plant pathogens, e.g. Fusarium, Septoria WO 2008/125245 PCT/EP2008/002759 -22 Structure affected / protein expressed Feature of the plant / tolerance to pyrrolnitrin synthesis gene plant pathogens, e.g. Fusarium, Septoria serine/threonine kinases plant pathogens, e.g. Fusarium, Septoria and other diseases polypeptide having the effect of triggering plant pathogens, e.g. Fusarium, Septoria and a hypersensitivity reaction other diseases systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases plant pathogens glucanases plant pathogens double-strand ribonuclease viruses such as, for example, BYDV and MSMV envelope proteins viruses such as, for example, BYDV and MSMV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, Coleoptera, Diptera, Bacillus cereus toxins, Photorabdus and nematodes Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, Coleoptera, Diptera, nematodes peroxidase Lepidoptera, Coleoptera, Diptera, nematodes aminopeptidase inhibitors, e.g. leucine Lepidoptera, Coleoptera, Diptera, aminopeptidase inhibitor nematodes lectins Lepidoptera, Coleoptera, Diptera, nematodes, aphids protease inhibitors, e.g, cystatin, patatin, Lepidoptera, Coleoptera, Diptera, virgiferin, CPTI nematodes, aphids ribosome-inactivating protein Lepidoptera, Coleoptera, Diptera, nematodes, aphids HMG-CoA reductase Lepidoptera, Coleoptera, Diptera, nematodes, aphids Plant: Rice Structure affected/ principle expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolepyrimidines, pyrimidyloxybenzoates, WO 2008/125245 PCT/EP2008/002759 -23 Structure affected/ principle expressed Feature of the plant / tolerance to phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acid, cyclohexanedione hydroxyphenylpyruvate dioxygenase (HPPD) isooxazoles, such as isoxaflutol or isoxachlortol, triones, such as mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin O-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles, such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUI xenobiotics and herbicides, such as sulphonylurea compounds antifungal polypeptide AIyAFP plant pathogens glucose oxidase plant pathogens pyrrolnitrin synthesis gene plant pathogens serine/threonine kinases plant pathogens phenylalanine ammonia lyase (PAL) plant pathogens, e.g. bacterial foliar mildew and inducible rice blast phytoalexins plant pathogens, e.g. bacterial foliar mildew and rice blast B-1,3-glucanase (antisense) plant pathogens, e.g. bacterial foliar mildew and rice blast receptor kinase plant pathogens, e.g. bacterial foliar mildew and rice blast polypeptide having the effect of triggering plant pathogens WO 2008/125245 PCT/EP2008/002759 -24 Structure affected/ principle expressed Feature of the plant / tolerance to a hypersensitivity reaction systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases plant pathogens, e.g. bacterial foliar mildew and rice blast glucanases plant pathogens double-strand ribonuclease viruses such as, for example, BYDV and MSMV envelope proteins viruses such as, for example, BYDV and MSMV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, e.g. stem borer, Coleoptera, Bacillus cereus toxins, Photorabdus and e.g. weevils such as Lissorhoptrus oryzophilus, Xenorhabdus toxins Diptera, rice planthoppers, e.g. rice brown planthopper 3-hydroxysteroid oxidase Lepidoptera, e.g. stem borer, Coleoptera, e.g. weevils such as Lissorhoptrus oryzophilus, Diptera, rice planthoppers, e.g. rice brown planthopper peroxidase Lepidoptera, e.g. stem borer, Coleoptera, e.g. weevils such as Lissorhoptrus oryzophilus, Diptera, rice planthoppers, e.g. rice brown planthopper aminopeptidase inhibitors, e.g. leucine Lepidoptera, e.g. stem borer, Coleoptera, aminopeptidase inhibitor e.g. weevils such as Lissorhoptrus oryzophilus, Diptera, rice planthoppers, e.g. rice brown planthopper lectins Lepidoptera, e.g. stem borer, Coleoptera, e.g. weevils such as Lissorhoptrus oryzophilus, Diptera, rice planthoppers, e.g. rice brown planthopper protease inhibitors Lepidoptera, e.g. stem borer, Coleoptera, e.g. weevils such as Lissorhoptrus oryzophilus, Diptera, rice planthoppers e.g. rice brown planthopper ribosome-inactivating protein Lepidoptera, e.g. stem borer, Coleoptera, e.g. weevils such as Lissorhoptrus WO 2008/125245 PCT/EP2008/002759 -25 Structure affected/ principle expressed Feature of the plant / tolerance to oryzophilus, Diptera, rice planthoppers, e.g. rice brown planthopper HMG-CoA reductase Lepidoptera, e.g. stem borer, Coleoptera, e.g. weevils such as Lissorhoptrus oryzophilus, Diptera, rice planthoppers e.g. rice brown planthopper Plant: Soya bean Structure affected/ principle expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolepyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isooxazoles, such as isoxaflutol or isoxachlortol, triones, such as mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles, such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUI or selection xenobiotics and herbicides, such as sulphonylurea compounds antifungal polypeptide AlyAFP bacterial and fungal pathogens such as, for WO 2008/125245 PCT/EP2008/002759 -26 Structure affected/ principle expressed Feature of the plant / tolerance to example, Fusarium, Sclerotinia, stem rot oxalate oxidase bacterial and fungal pathogens such as, for example, Fusarium, Sclerotinia, stem rot glucose oxidase bacterial and fungal pathogens such as, for example, Fusarium, Sclerotinia, stem rot pyrrolnitrin synthesis gene bacterial and fungal pathogens such as, for example, Fusarium, Sclerotinia, stem rot serine/threonine kinases bacterial and fungal pathogens such as, for example, Fusarium, Sclerotinia, stem rot phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as, for example, Fusarium, Sclerotinia, stem rot phytoalexins plant pathogens, e.g. bacterial foliar mildew and rice blast B-1,3-glucanase (antisense) plant pathogens, e.g. bacterial foliar mildew and rice blast receptor kinase bacterial and fungal pathogens such as, for example, Fusarium, Sclerotinia, stem rot polypeptide having the effect of triggering plant pathogens a hypersensitivity reaction systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases bacterial and fungal pathogens such as, for example, Fusarium, Sclerotinia, stem rot glucanases bacterial and fungal pathogens such as, for example, Fusarium, Sclerotinia, stem rot double-strand ribonuclease viruses such as, for example, BPMV and SbMV envelope proteins viruses such as, for example, BYDV and MSMV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, Coleoptera, aphids Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, Coleoptera, aphids peroxidase Lepidoptera, Coleoptera, aphids aminopeptidase inhibitors, e.g. leucine Lepidoptera, Coleoptera, aphids aminopeptidase inhibitor WO 2008/125245 PCT/EP2008/002759 -27 Structure affected/ principle expressed Feature of the plant / tolerance to lectins Lepidoptera, Coleoptera, aphids protease inhibitors, e.g. virgiferin Lepidoptera, Coleoptera, aphids ribosome-inactivating protein Lepidoptera, Coleoptera, aphids HMG-CoA reductase Lepidoptera, Coleoptera, aphids barnase nematodes, e.g. root-knot nematodes and cyst nematodes hatching factor for cyst nematodes cyst nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and cyst nematodes Plant: Potato Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolepyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isooxazoles, such as isoxaflutol or isoxachlortol, triones, such as mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of rMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles, such as bromoxynil and loxinyl 5 -enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc.

WO 2008/125245 PCT/EP2008/002759 -28 Structure affected / protein expressed Feature of the plant / tolerance to cytochrome P450 eg. P450 SUI or selection xenobiotics and herbicides, such as sulphonylurea compounds polyphenol oxidase or polyphenol oxidase black spot (antisense) metallothionein bacterial and fungal pathogens such as, for example, Phytophtora, ribonuclease Phytophtora, Verticillium, Rhizoctonia antifungal polypeptide AlyAFP bacterial and fungal pathogens such as, for example, Phytophtora oxalate oxidase bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia glucose oxidase bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia pyrrolnitrin synthesis gene bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia serine/threonine kinases bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia cecropin B bacteria such as, for example, Coryne bacterium sepedonicum, Erwinia carotovora phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia phytoalexins bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia B-1,3-glucanase (antisense) bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia receptor kinase bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia polypeptide having the effect of triggering bacterial and fungal pathogens such as, for WO 2008/125245 PCT/EP2008/002759 -29 Structure affected / protein expressed Feature of the plant / tolerance to a hypersensitivity reaction example, Phytophtora, Verticillium, Rhizoc tonia systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia barnase bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia gene 49 for controlling disease resistance bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia trans-aldolase (antisense) black spot glucanases bacterial and fungal pathogens such as, for example, Phytophtora, Verticillium, Rhizoc tonia double-strand ribonuclease viruses such as, for example, PLRV, PVY and TRV envelope proteins viruses such as, for example, PLRV, PVY and TRV 17kDa or 60 kDa protein viruses such as, for example, PLRV, PVY and TRV nuclear inclusion proteins, e.g. a or b viruses such as, for example, PLRV, PVY and TRV pseudoubiquitin viruses such as, for example, PLRV, PVY and TRV replicase viruses such as, for example, PLRV, PVY and TRV toxins of Bacillus thuringiensis, VIP 3, Coleoptera, e.g. Colorado beetle, aphids Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3-hydroxysteroid oxidase Coleoptera, e.g. Colorado beetle, aphids peroxidase Coleoptera, e.g. Colorado beetle, aphids aminopeptidase inhibitors, e.g. leucine Coleoptera, e.g. Colorado beetle, aphids aminopeptidase inhibitor WO 2008/125245 PCT/EP2008/002759 -30 Structure affected / protein expressed Feature of the plant / tolerance to stilbene synthase Coleoptera, e.g. Colorado beetle, aphids lectins Coleoptera, e.g. Colorado beetle, aphids protease inhibitors, e.g. cystatin, patatin Coleoptera, e.g. Colorado beetle, aphids ribosomene-inactivating protein Coleoptera, e.g. Colorado beetle, aphids HMG-CoA reductase Coleoptera, e.g. Colorado beetle, aphids hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and cyst nematodes Plant: Tomato Structure affected/ principle expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolepyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acid, cyclohexanedione hydroxyphenylpyruvate dioxygenase (HPPD) isooxazoles, such as isoxaflutol or isoxachlortol, triones, such as mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles, such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, WO 2008/125245 PCT/EP2008/002759 -31 Structure affected/ principle expressed Feature of the plant / tolerance to phenopylate, oxadiazoles etc. Cytochrome P450 e.g. P450 SUI or selection xenobiotics and herbicides, such as sulphonylurea compounds polyphenol oxidase or polyphenol oxidase black spot (antisense) metallothionein bacterial and fungal pathogens such as, for example, Phytophtora ribonuclease Phytophtora, Verticillium, Rhizoctonia antifungal polypeptide AlyAFP bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. oxalate oxidase bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. glucose oxidase bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. pyrrolnitrin synthesis gene bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. serine/threonine kinases bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. cecropin B bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc.

WO 2008/125245 PCT/EP2008/002759 -32 Structure affected/ principle expressed Feature of the plant / tolerance to Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 leaf mould osmotin early blight alpha hordothionin bakteria systemin bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. polygalacturonase inhibitors bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. Prf control gene bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. 12 fusarium resistance site Fusarium phytoalexins bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. B-1,3-glucanase (antisense) bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. receptor kinase bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. polypeptide having the effect of triggering bacterial and fungal pathogens such as, for a hypersensitivity reaction example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, WO 2008/125245 PCT/EP2008/002759 -33 Structure affected/ principle expressed Feature of the plant / tolerance to soft rot, powdery mildew, foliar blight, leaf mould etc. barnase bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. glucanases bacterial and fungal pathogens such as, for example, bacterial blotch, Fusarium, soft rot, powdery mildew, foliar blight, leaf mould etc. double-strand ribonuclease viruses such as, for example, PLRV, PVY and ToMoV envelope proteins viruses such as, for example, PLRV, PVY and ToMoV 17kDa or 60 kDa protein viruses such as, for example, PLRV, PVY and ToMoV nuclear inclusion proteins e.g. a or b or viruses such as, for example, PLRV, PVY and ToMoV nucleoprotein TRV pseudoubiquitin viruses such as, for example, PLRV, PVY and ToMoV replicase viruses such as, for example, PLRV, PVY and ToMoV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera e.g. Heliothis, whitefly Bacilluscereus toxins, Photorabdus and aphids Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera e.g. Heliothis, whitefly, aphids peroxidase Lepidoptera e.g. Heliothis, whitefly, aphids aminopeptidase inhibitors, e.g. leucine Lepidoptera e.g. Heliothis, whitefly, aminopeptidase inhibitor aphids lectins Lepidoptera e.g. Heliothis, whitefly, aphids protease inhibitors, e.g. cystatin, patatin Lepidoptera e.g. Heliothis, whitefly, aphids WO 2008/125245 PCT/EP2008/002759 - 34 Structure affected/ principle expressed Feature of the plant / tolerance to ribosome-inactivating protein Lepidoptera e.g. Heliothis, whitefly, aphids stilbene synthase Lepidoptera e.g. Heliothis, whitefly, aphids HMG-CoA reductase Lepidoptera e.g. Heliothis, whitefly, aphids hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and cyst nematodes Plant: Bell Pepper Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, WO 20081125245 PCT/EP2008/002759 - 35 Structure affected / protein expressed Feature of the plant / tolerance to phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUI or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial and fungal pathogens (antisense) metallothionein bacterial and fungal pathogens ribonuclease bacterial and fungal pathogens antifungal polypeptid AlyAFP bacterial and fungal pathogens oxalate oxidase bacterial and fungal pathogens glucose oxidase bacterial and fungal pathogens pyrrolnitrin synthesis genes bacterial and fungal pathogens serine/threonine kinases bacterial and fungal pathogens cecropin B bacterial and fungal pathogens, rot, leaf mould, etc. phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens Cf genes, e.g. Cf 9 Ct5 Cf4 Cf2 bacterial and fungal pathogens osmotin bacterial and fungal pathogens alpha hordothionine bacterial and fungal pathogens systemin bacterial and fungal pathogens polygalacturonase inhibitors bacterial and fungal pathogens Prf control gene bacterial and fungal pathogens 12 Fusarium resistance site Fusarium phytoalexins bacterial and fungal pathogens B-1,3-glucanase (antisense) bacterial and fungal pathogens receptor kinase bacterial and fungal pathogens polypeptide having the effect of triggering bacterial and fungal pathogens a hypersensitivity reaction systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases bacterial and fungal pathogens barnase bacterial and fungal pathogens glucanases bacterial and fungal pathogens double-strand ribonuclease viruses such as, for example, CMV, TEV envelope proteins viruses such as, for example, CMV, TEV 17kDa or 60 kDa protein viruses such as, for example, CMV, TEV WO 2008/125245 PCT/EP2008/002759 - 36 Structure affected / protein expressed Feature of the plant / tolerance to nuclear inclusion proteins e.g. a or b or viruses such as, for example, CMV, TEV nucleoprotein pseudoubiquitin viruses such as, for example, CMV, TEV replicase viruses such as, for example, CMV, TEV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, whitefly, aphids Bacilluscereus toxins, Photorabdus and Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, whitefly, aphids peroxidase Lepidoptera, whitefly, aphids aminopeptidase inhibitors, e.g. leucine Lepidoptera, whitefly, aphids aminopeptidase inhibitor lectins Lepidoptera, whitefly, aphids protease inhibitors, e.g. cystatin, patatin Lepidoptera, whitefly, aphids ribosome-inactivating protein Lepidoptera, whitefly, aphids stilbene synthase Lepidoptera, whitefly, aphids HMG-CoA reductase Lepidoptera, whitefly, aphids hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and cyst nematodes Plant: Grapevines Structure affected/ principle expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos WO 2008/125245 PCT/EP2008/002759 -37 Structure affected/ principle expressed Feature of the plant / tolerance to adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUI or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial and fungal pathogens such as (antisense) Botrytis and powdery mildew metallothionein bacterial and fungal pathogens such as Botrytis and powdery mildew ribonuclease bacterial and fungal pathogens such as Botrytis and powdery mildew antifungal polypeptide AlyAFP bacterial and fungal pathogens such as Botrytis and powdery mildew oxalate oxidase bacterial and fungal pathogens such as Botrytis and powdery mildew glucose oxidase bacterial and fungal pathogens such as Botrytis and powdery mildew pyrrolnitrin synthesis genes bacterial and fungal pathogens such as Botrytis and powdery mildew serine/threonine kinases bacterial and fungal pathogens such as Botrytis and powdery mildew cecropin B bacterial and fungal pathogens such as Botrytis and powdery mildew phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as Botrytis and powdery mildew Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens such as Botrytis and powdery mildew WO 2008/125245 PCT/EP2008/002759 -38 Structure affected/ principle expressed Feature of the plant / tolerance to osmotin bacterial and fungal pathogens such as Botrytis and powdery mildew alpha hordothionine bacterial and fungal pathogens such as Botrytis and powdery mildew systemin bacterial and fungal pathogens such as Botrytis and powdery mildew polygalacturonase inhibitors bacterial and fungal pathogens such as Botrytis and powdery mildew Prf control gene bacterial and fungal pathogens such as Botrytis and powdery mildew phytoalexins bacterial and fungal pathogens such as Botrytis and powdery mildew B-1,3-glucanase (antisense) bacterial and fungal pathogens such as Botrytis and powdery mildew receptor kinase bacterial and fungal pathogens such as Botrytis and powdery mildew polypeptide having the effect of triggering bacterial and fungal pathogens such as Botrytis a hypersensitivity reaction and powdery mildew systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases bacterial and fungal pathogens such as Botrytis and powdery mildew bamase bacterial and fungal pathogens such as Botrytis and powdery mildew glucanases bacterial and fungal pathogens such as Botrytis and powdery mildew double-strand ribonuclease viruses envelope proteins viruses l7kDa or 60 kDa protein viruses nuclear inclusion proteins e.g. a or b or viruses nucleoprotein pseudoubiquitin viruses replicase viruses toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids Bacilluscereus toxins, Photorabdus and Xenorhabdus toxins WO 2008/125245 PCT/EP2008/002759 -39 Structure affected/ principle expressed Feature of the plant / tolerance to 3-hydroxysteroid oxidase Lepidoptera, aphids peroxidase Lepidoptera, aphids aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids aminopeptidase inhibitor lectins Lepidoptera, aphids protease inhibitors, e.g. cystatin, patatin Lepidoptera, aphids ribosome-inactivating protein Lepidoptera, aphids stilbene synthase Lepidoptera, aphids, diseases HMG-CoA reductase Lepidoptera, aphids hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes or general diseases CBI root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes or root-cyst nematodes Plant: Oilseed rape Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl WO 2008/125245 PCT/EP2008/002759 - 40 Structure affected / protein expressed Feature of the plant / tolerance to 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUI or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase polyolyphenol oxidase bacterial and fungal pathogens such as (antisense) Cylindrosporium, Phoma, Sclerotinia metallothionein bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia ribonuclease bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia antifungal polypeptid AlyAFP bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia oxalate oxidase bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia glucose oxidase bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia pyrrolnitrin synthesis genes bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia serine/threonine kinases bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia cecropin B bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia osmotin bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia alpha hordothionine bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia systemin bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia polygalacturonase inhibitors bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia Prf control gene bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia WO 2008/125245 PCT/EP2008/002759 - 41 Structure affected / protein expressed Feature of the plant / tolerance to phytoalexins bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia B-1,3-glucanase (antisense) bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia receptor kinase bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia polypeptide having the effect of triggering bacterial and fungal pathogens such as a hypersensitivity reaction Cylindrosporium, Phoma, Sclerotinia systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia barnase bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia nematodes glucanases bacterial and fungal pathogens such as Cylindrosporium, Phoma, Sclerotinia double-strand ribonuclease viruses envelope proteins viruses l7kDa or 60 kDa protein viruses nuclear inclusion proteins e.g. a or b or viruses nucleoprotein pseudoubiquitin viruses replicase viruses toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids Bacilluscereus toxins, Photorabdus and Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, aphids peroxidase Lepidoptera, aphids aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids aminopeptidase inhibitor lectins Lepidoptera, aphids protease inhibitors, e.g. cystatin, patatin, Lepidoptera, aphids CPTI ribosome-inactivating protein Lepidoptera, aphids stilbene synthase Lepidoptera, aphids, diseases HMG-CoA reductase Lepidoptera, aphids WO 2008/125245 PCT/EP2008/002759 -42 Structure affected / protein expressed Feature of the plant / tolerance to hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes CBI root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and induced at nematode feeding sites root-cyst nematodes Plant: Brassica vegetables (cabbage, Brussels sprouts etc.) Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUl or selection xenobiotics and herbicides such as, for WO 2008/125245 PCT/EP2008/002759 -43 Structure affected / protein expressed Feature of the plant / tolerance to example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial and fungal pathogens (antisense) metallothionein bacterial and fungal pathogens ribonuclease bacterial and fungal pathogens antifungal polypeptid AlyAFP bacterial and fungal pathogens oxalate oxidase bacterial and fungal pathogens glucose oxidase bacterial and fungal pathogens pyrrolnitrin synthesis genes bacterial and fingal pathogens serine/threonine kinases bacterial and fungal pathogens cecropin B bacterial and fungal pathogens phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens osmotin bacterial and fungal pathogens alpha hordothionine bacterial and fungal pathogens systemin bacterial and fungal pathogens polygalacturonase inhibitors bacterial and fungal pathogens Prf control gene bacterial and fungal pathogens phytoalexins bacterial and fungal pathogens B-1,3-glucanase (antisense) bacterial and fungal pathogens receptor kinase bacterial and fungal pathogens polypeptide having the effect of triggering bacterial and fungal pathogens a hypersensitivity reaction systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens chitinases bacterial and fungal pathogens barnase bacterial and fungal pathogens glucanases bacterial and fungal pathogens double-strand ribonuclease viruses envelope proteins viruses 17kDa or 60 kDa protein viruses nuclear inclusion proteins e.g. a or b or viruses nucleoprotein pseudoubiquitin viruses replicase viruses toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids WO 2008/125245 PCT/EP2008/002759 -44 Structure affected / protein expressed Feature of the plant / tolerance to Bacilluscereus toxins, Photorabdus and Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, aphids peroxidase Lepidoptera, aphids aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids aminopeptidase inhibitor lectins Lepidoptera, aphids protease inhibitors, e~g. cystatin, patatin, Lepidoptera, aphids CPTI ribosome-inactivating protein Lepidoptera, aphids stilbene synthase Lepidoptera, aphids, diseases HMG-CoA reductase Lepidoptera, aphids hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes CBI root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and induced at nematode feeding sites root-cyst nematodes cyst nematodes Plants: Pomaceous fruit, e.g. apples, pears Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis WO 2008/125245 PCT/EP2008/002759 - 45 Structure affected / protein expressed Feature of the plant / tolerance to anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUl or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial and fungal pathogens such as (antisense) storage scab on apples or fire-blight metallothionein bacterial and fungal pathogens such as storage scab on apples or fire-blight ribonuclease bacterial and fungal pathogens such as storage scab on apples or fire-blight antifungal polypeptid AlyAFP bacterial and fungal pathogens such as storage scab on apples or fire-blight oxalate oxidase bacterial and fungal pathogens such as storage scab on apples or fire-blight glucose oxidase bacterial and fungal pathogens such as storage scab on apples or fire-blight pyrrolnitrin synthesis genes bacterial and fungal pathogens such as storage scab on apples or fire-blight serine/threonine kinases bacterial and fungal pathogens such as storage scab on apples or fire-blight cecropin B bacterial and fungal pathogens such as storage scab on apples or fire-blight phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as storage scab on apples or fire-blight Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens such as storage scab on apples or fire-blight osmotin bacterial and fungal pathogens such as storage scab on apples or fire-blight WO 2008/125245 PCT/EP2008/002759 -46 Structure affected / protein expressed Feature of the plant / tolerance to alpha hordothionine bacterial and fungal pathogens such as storage scab on apples or fire-blight systemin bacterial and fungal pathogens such as storage scab on apples or fire-blight polygalacturonase inhibitors bacterial and fungal pathogens such as storage scab on apples or fire-blight Prf control gene bacterial and fungal pathogens such as storage scab on apples or fire-blight phytoalexins bacterial and fungal pathogens such as storage scab on apples or fire-blight B-1,3-glucanase (antisense) bacterial and fungal pathogens such as storage scab on apples or fire-blight receptor kinase bacterial and fungal pathogens such as storage scab on apples or fire-blight polypeptide having the effect of triggering bacterial and fungal pathogens such as a hypersensitivity reaction storage scab on apples or fire-blight systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens lytic protein bacterial and fungal pathogens such as storage scab on apples or fire-blight lysozyme bacterial and fungal pathogens such as storage scab on apples or fire-blight chitinases bacterial and fungal pathogens such as storage scab on apples or fire-blight barnase bacterial and fungal pathogens such as storage scab on apples or fire-blight glucanases bacterial and fungal pathogens such as storage scab on apples or fire-blight double-strand ribonuclease viruses envelope proteins viruses 17kDa or 60 kDa protein viruses nuclear inclusion proteins e.g. a or b or viruses nucleoprotein pseudoubiquitin viruses replicase viruses toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids, mites WO 2008/125245 PCT/EP2008/002759 - 47 Structure affected / protein expressed Feature of the plant / tolerance to Bacilluscereus toxins, Photorabdus and Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, aphids, mites peroxidase Lepidoptera, aphids, mites aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids, mites aminopeptidase inhibitor lectins Lepidoptera, aphids, mites protease inhibitors, e.g. cystatin, patatin, Lepidoptera, aphids, mites CPTI ribosome-inactivating protein Lepidoptera, aphids, mites stilbene synthase Lepidoptera, aphids, diseases, mites HMG-CoA reductase Lepidoptera, aphids, mites hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes CBI root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and induced at nematode feeding sites root-cyst nematodes Plant: Melon Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and WO 2008/125245 PCT/EP2008/002759 -48 Structure affected / protein expressed Feature of the plant / tolerance to degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUl or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial or fingal pathogens such as (antisense) Phytophtora metallothionein bacterial or fungal pathogens such as Phytophtora ribonuclease bacterial or fungal pathogens such as Phytophtora antifungal polypeptid AlyAFP bacterial or fungal pathogens such as Phytophtora oxalate oxidase bacterial or fungal pathogens such as Phytophtora glucose oxidase bacterial or fungal pathogens such as Phytophtora pyrrolnitrin synthesis genes bacterial or fungal pathogens such as Phytophtora serine/threonine kinases bacterial or fungal pathogens such as Phytophtora cecropin B bacterial or fungal pathogens such as Phytophtora phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens such as Phytophtora Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens such as Phytophtora osmotin bacterial or fungal pathogens such as Phytophtora alpha hordothionine bacterial or fungal pathogens such as WO 2008/125245 PCT/EP2008/002759 -49 Structure affected / protein expressed Feature of the plant / tolerance to Phytophtora systemin bacterial or fungal pathogens such as Phytophtora polygalacturonase inhibitors bacterial or fungal pathogens such as Phytophtora Prf control gene bacterial or fungal pathogens such as Phytophtora phytoalexins bacterial or fungal pathogens such as Phytophtora B-1,3-glucanase (antisense) bacterial or fungal pathogens such as Phytophtora receptor kinase bacterial or fungal pathogens such as Phytophtora polypeptide having the effect of triggering bacterial or fungal pathogens such as a hypersensitivity reaction Phytophtora systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens lytic protein bacterial or fungal pathogens such as Phytophtora lysozyme bacterial or fungal pathogens such as Phytophtora chitinases bacterial or fungal pathogens such as Phytophtora barnase bacterial or fungal pathogens such as Phytophtora glucanases bacterial or fungal pathogens such as Phytophtora double-strand ribonuclease viruses such as CMV, PRSV, WMV2, SMV, ZYMV envelope proteins viruses such as CMV, PRSV, WMV2, SMV, ZYMV 17kDa or 60 kDa protein viruses such as CMV, PRSV, WMV2, SMV, ZYMV nuclear inclusion proteins e.g. a or b or viruses such as CMV, PRSV, WMV2, SMV, nucleoprotein ZYMV pseudoubiquitin viruses such as CMV, PRSV, WMV2, SMV, WO 2008/125245 PCT/EP2008/002759 -50 Structure affected! protein expressed Feature of the plant / tolerance to ZYMV replicase viruses such as CMV, PRSV, WMV2, SMV, ZYMV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids, mites Bacilluscereus toxins, Photorabdus and Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, aphids, mites, whitefly peroxidase Lepidoptera, aphids, mites, whitefly aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids, mites, whitefly aminopeptidase inhibitor lectins Lepidoptera, aphids, mites, whitefly protease inhibitors, e.g. cystatin, patatin, Lepidoptera, aphids, mites, whitefly CPTI, virgiferin ribosome-inactivating protein Lepidoptera, aphids, mites, whitefly stilbene synthase Lepidoptera, aphids, mites, whitefly HMG-CoA reductase Lepidoptera, aphids, mites, whitefly hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes CBI root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and induced at nematode feeding sites root-cyst nematodes Plant: Banana Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin WO 2008/125245 PCT/EP2008/002759 -51 Structure affected / protein expressed Feature of the plant / tolerance to 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SU I or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial or fungal pathogens (antisense) metallothionein bacterial or fungal pathogens ribonuclease bacterial or fungal pathogens antifungal polypeptid AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens cecropin B bacterial or fungal pathogens phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens osmotin bacterial or fungal pathogens alpha hordothionine bacterial or fungal pathogens systemin bacterial or fungal pathogens polygalacturonase inhibitors bacterial or fungal pathogens Prf control gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase (antisense) bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens WO 2008/125245 PCT/EP2008/002759 -52 Structure affected / protein expressed Feature of the plant / tolerance to polypeptide having the effect of triggering bacterial or fungal pathogens a hypersensitivity reaction systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens lytic protein bacterial or fungal pathogens lysozyme bacterial or fungal pathogens chitinases bacterial or fungal pathogens bamase bacterial or fungal pathogens glucanases bacterial or fungal pathogens double-strand ribonuclease viruses such as the Banana Bunchy Top Virus (BBTV) envelope proteins viruses such as the Banana Bunchy Top Virus (BBTV) l7kDa or 60 kDa protein viruses such as the Banana Bunchy Top Virus (BBTV) nuclear inclusion proteins e.g. a or b or viruses such as the Banana Bunchy Top Virus nucleoprotein (BBTV) pseudoubiquitin viruses such as the Banana Bunchy Top Virus (BBTV) replicase viruses such as the Banana Bunchy Top Virus (BBTV) toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids, mites, nematodes Bacilluscereus toxins, Photorabdus and Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, aphids, mites, nematodes peroxidase Lepidoptera, aphids, mites, nematodes aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids, mites, nematodes aminopeptidase inhibitor lectins Lepidoptera, aphids, mites, nematodes protease inhibitors, e.g. cystatin, patatin, Lepidoptera, aphids, mites, nematodes CPTI, virgiferin ribosome-inactivating protein Lepidoptera, aphids, mites, nematodes stilbene synthase Lepidoptera, aphids, mites, nematodes I-IMG-CoA reductase Lepidoptera, aphids, mites, nematodes hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and WO 2008/125245 PCT/EP2008/002759 -53 Structure affected / protein expressed Feature of the plant / tolerance to cyst nematodes CBI root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and induced at nematode feeding sites root-cyst nematodes Plant: Cotton Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthese adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUl or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial or fungal pathogens (antisense) WO 2008/125245 PCT/EP2008/002759 - 54 metallothionein bacterial or fungal pathogens ribonuclease bacterial or fungal pathogens antifungal polypeptid AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens cecropin B bacterial or fungal pathogens phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens osmotin bacterial or fungal pathogens alpha hordothionine bacterial or fingal pathogens systemin bacterial or fungal pathogens polygalacturonase inhibitors bacterial or fungal pathogens Prf control gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase (antisense) bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens polypeptide having the effect of triggering bacterial or fungal pathogens a hypersensitivity reaction systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens lytic protein bacterial or fungal pathogens lysozyme bacterial or fungal pathogens chitinases bacterial or fungal pathogens barnase bacterial or fungal pathogens glucanases bacterial or fungal pathogens double-strand ribonuclease viruses such as the wound tumour virus (WTV) envelope proteins viruses such as the wound tumour virus (WTV) 17kDa or 60 kDa protein viruses such as the wound tumour virus (WTV) nuclear inclusion proteins e.g. a or b or viruses such as the wound tumour virus (WTV) nucleoprotein pseudoubiquitin viruses such as the wound tumour virus (WTV) replicase viruses such as the wound tumour virus (WTV) toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids, mites, nematodes, Bacilluscereus toxins, Photorabdus and whitefly Xenorhabdus toxins WO 2008/125245 PCT/EP2008/002759 -55 3-hydroxysteroid oxidase Lepidoptera, aphids, mites, nematodes, whitefly peroxidase Lepidoptera, aphids, mites, nematodes, whitefly aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly lectins Lepidoptera, aphids, mites, nematodes, whitefly protease inhibitors, e.g. cystatin, patatin, Lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly ribosome-inactivating protein Lepidoptera, aphids, mites, nematodes, whitefly stilbene synthase Lepidoptera, aphids, mites, nematodes, whitefly HMG-CoA reductase Lepidoptera, aphids, mites, nematodes, whitefly hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes CBI root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and induced at nematode feeding sites root-cyst nematodes Plant: Sugar cane Feature affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (-IPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos WO 2008/125245 PCT/EP2008/002759 -56 Feature affected / protein expressed Feature of the plant / tolerance to adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUl or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial or fungal pathogens (antisense) metallothionein bacterial or fungal pathogens ribonuclease bacterial or fungal pathogens antifungal polypeptid AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens cecropin B bacterial or fungal pathogens phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes, e~g. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens osmotin bacterial or fungal pathogens alpha hordothionine bacterial or fingal pathogens systemin bacterial or fungal pathogens polygalacturonase inhibitors bacterial or fungal pathogens Prf control gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase (antisense) bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens polypeptide having the effect of triggering bacterial or fungal pathogens a hypersensitivity reaction WO 2008/125245 PCT/EP2008/002759 -57 Feature affected / protein expressed Feature of the plant / tolerance to systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens lytic protein bacterial or fungal pathogens lysozyme bacterial or fungal pathogens, e.g. Clavibacter chitinases bacterial or fungal pathogens barnase bacterial or fungal pathogens glucanases bacterial or fungal pathogens double-strand ribonuclease viruses such as SCMV, SrMV envelope proteins viruses such as SCMV, SrMV I7kDa or 60 kDa protein viruses such as SCMV, SrMV nuclear inclusion proteins e.g. a or b or viruses such as SCMV, SrMV nucleoprotein pseudoubiquitin viruses such as SCMV, SrMV replicase viruses such as SCMV, SrMV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids, mites, nematodes, Bacilluscereus toxins, Photorabdus and whitefly, beetles such as e.g. the Mexican Xenorhabdus toxins rice borer 3-hydroxysteroid oxidase Lepidoptera, aphids, mites, nematodes, whitefly, beetles such as e.g. the Mexican rice borer peroxidase Lepidoptera, aphids, mites, nematodes, whitefly, beetles such as e.g. the Mexican rice borer aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly, beetles such as e.g. the Mexican rice borer lectins Lepidoptera, aphids, mites, nematodes, whitefly, beetles such as e.g. the Mexican rice borer protease inhibitors, e.g. cystatin, patatin, Lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly, beetles such as e.g. the Mexican rice borer ribosome-inactivating protein Lepidoptera, aphids, mites, nematodes, whitefly, beetles such as e.g. the Mexican rice borer WO 2008/125245 PCT/EP2008/002759 -58 Feature affected / protein expressed Feature of the plant / tolerance to stilbene synthase Lepidoptera, aphids, mites, nematodes, whitefly, beetles such as e.g. the Mexican rice borer HMG-CoA reductase Lepidoptera, aphids, mites, nematodes, whitefly, beetles such as e.g. the Mexican rice borer hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes CBI root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and induced at nematode feeding sites root-cyst nematodes Plant: Sunflower Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin 0-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) WO 2008/125245 PCT/EP2008/002759 -59 Structure affected / protein expressed Feature of the plant / tolerance to glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrone P450 e.g. P450 SUl or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial or fungal pathogens (antisense) metallothionein bacterial or fungal pathogens ribonuclease bacterial or fungal pathogens antifungal polypeptid AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens, e.g. Sclerotinia glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens cecropin B bacterial or fungal pathogens phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens osmotin bacterial or fungal pathogens alpha hordothionine bacterial or fungal pathogens systemin bacterial or fungal pathogens polygalacturonase inhibitors bacterial or fungal pathogens Prf control gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase (antisense) bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens polypeptide having the effect of triggering bacterial or fungal pathogens a hypersensitivity reaction systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens lytic protein bacterial or fungal pathogens lysozyme bacterial or fungal pathogens chitinases bacterial or fungal pathogens barnase bacterial or fungal pathogens WO 2008/125245 PCT/EP2008/002759 -60 Structure affected / protein expressed Feature of the plant / tolerance to glucanases bacterial or fungal pathogens double-strand ribonuclease viruses such as CMV, TMV envelope proteins viruses such as CMV, TMV 17kDa or 60 kDa protein viruses such as CMV, TMV nuclear inclusion proteins e.g. a or b or viruses such as CMV, TMV nucleoprotein pseudoubiquitin viruses such as CMV, TMV replicase viruses such as CMV, TMV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids, mites, nematodes, Bacilluscereus toxins, Photorabdus and whitefly, beetles Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, aphids, mites, nematodes, whitefly, beetles peroxidase Lepidoptera, aphids, mites, nematodes, whitefly, beetles aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly, beetles lectins Lepidoptera, aphids, mites, nematodes, whitefly, beetles protease inhibitors, e.g. cystatin, patatin, Lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly, beetles ribosome-inactivating protein Lepidoptera, aphids, mites, nematodes, whitefly, beetles stilbene synthase Lepidoptera, aphids, mites, nematodes, whitefly, beetles HMG-CoA reductase Lepidoptera, aphids, mites, nematodes, whitefly, beetles hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes CBI root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and induced at nematode feeding sites root-cyst nematodes Plants: Sugar beet, turnips WO 2008/125245 PCT/EP2008/002759 -61 Structure affected / protein expressed Feature of the plant / tolerance to acetolactate synthase (ALS) sulphonylurea compounds, imidazolinones triazolopyrimidines, pyrimidyloxybenzoates, phthalides acetyl-CoA carboxylase (ACCase) aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones hydroxyphenylpyruvate dioxygenase (HPPD) isoxazoles such as, for example, isoxaflutole or isoxachlortole, triones such as, for example, mesotrione or sulcotrione phosphinothricin acetyltransferase phosphinothricin O-methyl transferase modified lignin content glutamine synthetase glufosinate, bialaphos adenylosuccinate lyase (ADSL) inhibitors of IMP and AMP synthesis adenylosuccinate synthase inhibitors of adenylosuccinate synthesis anthranilate synthase inhibitors of tryptophan synthesis and degradation nitrilase 3,5-dihalo-4-hydroxybenzonitriles such as bromoxynil and loxinyl 5-enolpyruvyl-3-phosphoshikimate glyphosate or sulphosate synthase (EPSPS) glyphosate oxidoreductase glyphosate or sulphosate protoporphyrinogen oxidase (PROTOX) diphenyl ethers, cyclic imides, phenylpyrazoles, pyridine derivatives, phenopylate, oxadiazoles etc. cytochrome P450 e.g. P450 SUI or selection xenobiotics and herbicides such as, for example, sulphonylurea compounds polyphenol oxidase or polyphenol oxidase bacterial or fungal pathogens (antisense) metallothionein bacterial or fungal pathogens ribonuclease bacterial or fungal pathogens antifungal polypeptid AlyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens, e.g. Sclerotinia glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens cecropin B bacterial or fungal pathogens WO 2008/125245 PCT/EP2008/002759 - 62 Structure affected / protein expressed Feature of the plant / tolerance to phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens osmotin bacterial or fungal pathogens alpha hordothionine bacterial or fungal pathogens systemin bacterial or fungal pathogens polygalacturonase inhibitors bacterial or fungal pathogens Prf control gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase (antisense) bacterial or fungal pathogens AX + WIN-proteins bacterial and fungal pathogens such as Cercospora beticola receptor kinase bacterial or fungal pathogens polypeptide having the effect of triggering bacterial or fungal pathogens a hypersensitivity reaction systemic aquired resistance (SAR) genes viral, bacterial, fungal and nematodal pathogens lytic protein bacterial or fungal pathogens lysozyme bacterial or fungal pathogens chitinases bacterial or fungal pathogens barnase bacterial or fungal pathogens glucanases bacterial or fungal pathogens double-strand ribonuclease viruses such as, for example, BNYVV envelope proteins viruses such as, for example, BNTYVV l7kDa or 60 kDa protein viruses such as, for example, BNYVV nuclear inclusion proteins e.g. a or b or viruses such as, for example, BNYVV nucleoprotein pseudoubiquitin viruses such as, for example, BNYVV replicase viruses such as, for example, BNYVV toxins of Bacillus thuringiensis, VIP 3, Lepidoptera, aphids, mites, nematodes, Bacilluscereus toxins, Photorabdus and whitefly, beetles, root-flies Xenorhabdus toxins 3-hydroxysteroid oxidase Lepidoptera, aphids, mites, nematodes, whitefly, beetles, root-flies peroxidase Lepidoptera, aphids, mites, nematodes, whitefly, beetles, root-flies aminopeptidase inhibitors, e.g. leucine Lepidoptera, aphids, mites, nematodes, WO 2008/125245 PCT/EP2008/002759 -63 Structure affected / protein expressed Feature of the plant / tolerance to aminopeptidase inhibitor whitefly, beetles, root-flies lectins Lepidoptera, aphids, mites, nematodes, whitefly, beetles, root-flies protease inhibitors, e.g. cystatin, patatin, Lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly, beetles, root-flies ribosome-inactivating protein Lepidoptera, aphids, mites, nematodes, whitefly, beetles, root-flies stilbene synthase Lepidoptera, aphids, mites, nematodes, whitefly, beetles, root-flies HMG-CoA reductase Lepidoptera, aphids, mites, nematodes, whitefly, beetles, root-flies hatching factor for cyst nematodes cyst nematodes barnase nematodes, e.g. root-knot nematodes and cyst nematodes beet cyst nematode resistance site cyst nematodes CBl root-knot nematodes principles for preventing food uptake nematodes, e.g. root-knot nematodes and induced root-cyst nematodes WO 2008/125245 PCT/EP2008/002759 -64 Table 2 In the table, the following abbreviations were used: active principle of the transgenic plant: AP Photorhabdus luminescens: PL 5 Xenorhabdus nematophilus: XN proteinase inhibitors: Plnh. plant lectins PLec. agglutinines: Aggl. 3-hydroxysteroid oxidase: HO 10 cholesterol oxidase: CO chitinase: CH glucanase: GL stilbene synthase: SS AP Control of CrylA(a) Adoxophyes spp. CrylA(a) Agrotis spp. CrylA(a) Alabama argiliaceae CrylA(a) Anticarsia gemmatalis CrylA(a) Chilo spp. CrylA(a) Clysia ambiguella CrylA(a) Crocidolomia binotalis CrylA(a) Cydia spp. CrylA(a) Diparopsis castanea CrylA(a) Earias spp. CrylA(a) Ephestia spp. CrylA(a) Heliothis spp. CrylA(a) Heliula undalis CrylA(a) Keiferia lycopersicella CrylA(a) Leucoptera scitella CrylA(a) Lithocollethis spp. CrylA(a) Lobesia botrana CrylA(a) Ostrinia nubilalis CrylA(a) Pandemis spp. CrylA(a) Pectinophora gossyp. CrylA(a) Phyllocnistis citrella WO 2008/125245 PCT/EP2008/002759 - 65 AP Control of CrylA(a) Pieris spp. CrylA(a) Plutella xylostella CrylA(a) Scirpophaga spp. CrylA(a) Sesamia spp. CrylA(a) Sparganothis spp. CrylA(a) Spodoptera spp. CrylA(a) Tortrix spp. CrylA(a) Trichoplusia ni CrylA(a) Agriotes spp. CrylA(a) Anthonomus grandis CrylA(a) Curculio spp. CrylA(a) Diabrotica balteata CryJA(a) Leptinotarsa spp. CrylA(a) Lissorhoptrus spp. CrylA(a) Otiorhynchus spp. CrylA(a) Aleurothrixus spp. CrylA(a) Aleyrodes spp. CrylA(a) Aonidiella spp. CrylA(a) Aphididea spp. CrylA(a) Aphis spp. CryIA(a) Bemisia tabaci CrylA(a) Empoasca spp. CrylA(a) Mycus spp. CryIA(a) Nephotettix spp. CrylA(a) Nilaparvata spp. CrylA(a) Pseudococcus spp. CryIA(a) Psylla spp. CrylA(a) Quadraspidiotus spp. CrylA(a) Schizaphis spp. CrylA(a) Trialeurodes spp. CryIA(a) Lyriomyza spp. CryIA(a) Oscinella spp. CryIA(a) Phorbia spp.

WO 2008/125245 PCT/EP2008/002759 - 66 AP Control of CrylA(a) Frankliniella spp. CrylA(a) Thrips spp. CrylA(a) Scirtothrips aurantii CrylA(a) Aceria spp. CrylA(a) Aculus spp. CrylA(a) Brevipaipus spp. CrylA(a) Panonychus spp. CrylA(a) Phyllocoptruta spp. CrylA(a) Tetranychus spp. CrylA(a) Heterodera spp. CrylA(a) Meloidogyne spp. CrylA(b) Adoxophyes spp CrylA(b) Agrotis spp CrylA(b) Alabama argillaceae CrylA(b) Anticarsia gemnatalis CrylA(b) Chilo spp. CrylA(b) Ciysia ambiguella CrylA(b) Crocidolomia binotaiis CrylA(b) Cydia spp. CrylA(b) Diparopsis castanea CrylA(b) Earias spp. CrylA(b) Ephestia spp. CrylA(b) Heliothis spp. CrylA(b) Hellula undalis CrylA(b) Keiferia lycopersicella CrylA(b) Leucoptera scitella CrylA(b) Lithocollethis spp. CrylA(b) Lobesia botrana CrylA(b) Ostrinia nubilalis CrylA(b) Pandemis spp. CrylA(b) Pectinophora gossyp. CrylA(b) Phyllocnistis citrella CrylA(b) Pieris spp.

WO 2008/125245 PCT/EP2008/002759 - 67 AP Control of CrylA(b) Plutelia xyiostella CrylA(b) Scirpophaga spp. CrylA(b) Sesamia spp. CrylA(b) Sparganothis spp. CrylA(b) Spodoptera spp. CrylA(b) Tortrix spp. CrylA(b) Trichoplusia ni CrylA(b) Agriotes spp. CrylA(b) Anthonomus grandis CrylA(b) Curculio spp. CrylA(b) Diabrotica balteata CrylA(b) Leptinotarsa spp. CrylA(b) Lissorhoptrus spp. CrylA(b) Otiorhynchus spp. CrylA(b) Aleurothrixus spp. CrylA(b) Aleyrodes spp. CrylA(b) Aonidiella spp. CrylA(b) Aphididae spp. CrylA(b) Aphis spp. CrylA(b) Bemisia tabaci CrylA(b) Empoasca spp. CrylA(b) Mycus spp. CrylA(b) Nephotettix spp. CrylA(b) Nilaparvata spp. CrylA(b) Pseudococcus spp. CrylA(b) Psylla spp. CrylA(b) Quadraspidiotus spp. CrylA(b) Schizaphis spp. CrylA(b) Trialeurodes spp. CrylA(b) Lyriomyza spp. CrylA(b) Oscinella spp. CrylA(b) Phorbia spp. CrylA(b) Frankliniella spp.

WO 2008/125245 PCT/EP2008/002759 -68 AP Control of CrylA(b) Thrips spp. CrylA(b) Scirtothrips aurantii CrylA(b) Aceria spp. CrylA(b) Aculus spp. CrylA(b) Brevipalpus spp. CrylA(b) Panonychus spp. CrylA(b) Phyllocoptruta spp. CrylA(b) Tetranychus spp. CrylA(b) Heterodera spp. CrylA(b) Meloidogyne spp. CrylA(c) Adoxophyes spp. CrylA(c) Agrotis spp. CrylA(c) Alabama argillaceae CrylA(c) Anticarsia gernmatalis CrylA(c) Chilo spp. CrylA(c) Ciysia ambiguella CrylA(c) Crocidolomia binotalis CrylA(c) Cydia spp. CrylA(c) Diparopsis castanea CrylA(c) Earias spp. CrylA(c) Ephestia spp. CrylA(c) Heliothis spp. CrylA(c) Hellula undalis CrylA(c) Keiferia lycopersicella CrylA(c) Leucoptera scitella CrylA(c) Lithocollethis spp. CrylA(c) Lobesia botrana CrylA(c) Ostrinia nubilalis CrylA(c) Pandemis spp. CrylA(c) Pectinophora gossypielia. CrylA(c) Phyllocnistis citrella CrylA(c) Pieris spp. CrylA(c) Plutella xyiostella WO 2008/125245 PCT/EP2008/002759 -69 AP Control of CrylA(c) Scirpophaga spp. CrylA(c) Sesamia spp. CrylA(c) Sparganothis spp. CrylA(c) Spodoptera spp. CrylA(c) Tortrix spp. CrylA(c) Trichoplusia ni CrylA(c) Agriotes spp. CrylA(c) Anthonomus grandis CrylA(c) Curculio spp. CrylA(c) Diabrotica baiteata CrylA(c) Leptinotarsa spp. CrylA(c) Lissorhoptrus spp. CrylA(c) Otiorhynchus spp. CryIA(c) Aleurothrixus spp. CrylA(c) Aleyrodes spp. CryIA(c) Aonidiella spp. CrylA(c) Aphididae spp. CrylA(c) Aphis spp. CrylA(c) Bemisia tabaci CrylA(c) Empoasca spp. CryIA(c) Mycus spp. CryIA(c) Nephotettix spp. CrylA(c) Nilaparvata spp. CrylA(c) Pseudococcus spp. CrylA(c) Psylla spp. CryIA(c) Quadraspidiotus spp. CrylA(c) Schizaphis spp. CrylA(c) Trialeurodes spp, CrylA(c) Lyriomyza spp. CrylA(c) Oscinelia spp. CrylA(c) Phorbia spp. CrylA(c) Frankliniella spp. CrylA(c) Thrips spp.

WO 2008/125245 PCT/EP2008/002759 -70 AP Control of CrylA(c) Scirtothrips aurantii CrylA(c) Aceria spp. CrylA(c) Aculus spp. CrylA(c) Brevipalpus spp. CrylA(c) Panonychus spp. CrylA(c) Phyllocoptruta spp. CrylA(c) Tetranychus spp. CrylA(c) Heterodera spp. CrylA(c) Meloidogyne spp. CryllA Adoxophyes spp. CryllA Agrotis spp. CryllA Alabama argillaceae CryllA Anticarsia gemmatalis CryllA Chilo spp. CryllA Clysia ambiguella CryllA Crocidolomia binotalis CryllA Cydia spp. CryllA Diparopsis castanea CryllA Earias spp. CryllA Ephestia spp. CryllA Heliothis spp. CryllA Hellula undalis CryllA Keiferia lycopersicella CryllA Leucoptera scitella CryllA Lithocoliethis spp, CryllA Lobesia botrana CryllA Ostrinia nubilalis CryllA Pandemis spp. CryllA Pectinophora gossyp. CryllA Phyllocnistis citrella CryllA Pieris spp. CryllA Plutella xylostella CryllA Scirpophaga spp.

WO 2008/125245 PCT/EP2008/002759 -71 AP Control of CryllA Sesamia spp. CryllA Sparganothis spp. CryllA Spodoptera spp. CryllA Tortrix spp. CryllA Trichoplusia ni CryllA Agriotes spp. CryllA Anthonomus grandis CryllA Curculio spp. CryllA Diabrotica balteata CryllA Leptinotarsa spp. CryllA Lissorhoptrus spp. CryllA Otiorhynchus spp. CryllA Aleurothrixus spp. CryllA Aleyrodes spp. CryllA Aonidiella spp. CryllA Aphididae spp. CryllA Aphis spp. CryllA Bemisia tabaci CryllA Empoasca spp. CryllA Mycus spp. CryllA Nephotettix spp. CryllA Nilaparvata spp. CryllA Pseudococcus spp. CryllA Psyila spp. CryllA Quadraspidiotus spp. CryllA Schizaphis spp. CryllA Trialeurodes spp. CryllA Lyriomyza spp. CryllA Oscinella spp. CryllA Phorbia spp. CryllA Frankliniella spp. CryllA Thrips spp. CryllA Scirtothrips aurantii WO 2008/125245 PCT/EP2008/002759 - 72 AP Control of CryllA Aceria spp. CryllA Acutus spp. CrylIA Brevipalpus spp. CryllA Panonychus spp. CryllA Phyllocoptruta spp. CryllA Tetranychus spp. CryllA Heterodera spp. CryllA Meloidogyne spp. CrylllA Adoxophyes spp. CrylIlA Agrotis spp. CrylllA Alabama argiiiaceae CrylllA Anticarsia gemmataiis CrylllA Chilo spp. CrylllA Ciysia ambiguelia CrylllA Crocodolomia binotalis CrylllA Cydia spp. CrylllA Diparopsis castanea CryllIA Earias spp. CrylllA Ephestia spp. CryllIA Heliothis spp. CrylllA Hellula undalis CrylliA Keiferia lycopersicella CrylliA Leucoptera scitella CrylllA Lithocollethis spp. CrylllA Lobesia botrana CrylliA Ostrinia nubilalis CrylllA Pandemis spp. CrylllA Pectinophora gossyp. CrylllA Phyllocnistis citrella CrylllA Pieris spp. CrylllA Plutella xylostella CrylllA Scirpophaga spp. CrylllA Sesamia spp.

WO 2008/125245 PCT/EP2008/002759 - 73 AP Control of CryIllA Sparganothis spp. CryllIA Spodoptera spp. CrylllA Tortrix spp. CrylllA Trichoplusia ni CrylllA Agriotes spp. CryllIA Anthonomus grandis CrylllA Curculio spp. CrylllA Diabrotica balteata CrylllA Leptinotarsa spp. CrylliA Lissorhoptrus spp. CryllIA Otiorhynchus spp. CrylliA Aleurothrixus spp. CrylllA Aleyrodes spp. CryllIA Aonidiella spp. CrylilA Aphididae spp. CrylliA Aphis spp. CrylllA Bemisia tabaci CrylllA Empoasca spp. CrylliA Mycus spp. CrylliA Nephotettix spp. CrylllA Nilaparvata spp. CrylllA Pseudococcus spp. CrylllA Psylla spp. CrylliA Quadraspidiotus spp. CrylllA Schizaphis spp. CrylllA Trialeurodes spp. CrylIIA Lyriomyza spp. CrylliA Oscinella spp. CryllIA Phorbia spp. CryllIA Frankliniella spp. CryllIA Thrips spp. CrylilA Scirtothrips aurantii CrylllA Aceria spp.

WO 2008/125245 PCT/EP2008/002759 - 74 AP Control of CrylllA Aculus spp. CryllIA Brevipalpus spp. CrylliA Panonychus spp. CrylliA Phyllocoptruta spp. CrylliA Tetranychus spp. CrylllA Heterodera spp. CrylllA Meloidogyne spp. CrylllB2 Adoxophyes spp. CryllIB2 Agrotis spp. CrylllB2 Alabama argiilaceae CryllIB2 Anticarsia gemmatalis CrylllB2 Chilo spp. CryllIB2 Clysia ambiguella CryllIB2 Crocidolomia binotalis CryllIB2 Cydia spp. CryllIB2 Diparopsis castanea CryllIB2 Earias spp. CrylllB2 Ephestia spp. CrylllB2 Heliothis spp. CryllIB2 Hellula undalis CrylllB2 Keiferia lycopersicella CrylllB2 Leucoptera sectelia CrylllB2 Lithocollethis spp. CrylllB2 Lobesia botrana CryIllB2 Ostrinia nubilalis CrylllB2 Pandemis spp. CrylllB2 Pectinophora gossyp. CrylllB2 Phyllocnistis citrella CrylllB2 Pieris spp. CrylllB2 Plutella xylostella CryllIB2 Scirpophaga spp. CryIIB2 Sesamia spp. CryllIB2 Sparganothis spp.

WO 2008/125245 PCT/EP2008/002759 -75 AP Control of CrylllB2 Spodoptera spp. CrylllB2 Tortrix spp. CrylllB2 Trichoplusia ni CrylllB2 Agriotes spp. CryllIB2 Anthonomus grandis CrylllB2 Curculio spp. CrylllB2 Diabrotica balteata CryIlB2 Leptinotarsa spp. CrylllB2 Lissorhoptrus spp. CrylliB2 Otiorhynchus spp. CrylllB2 Aleurothrixus spp. CrylllB2 Aleyrodes spp. CrylliB2 Aonidiella spp. CrylllB2 Aphididae spp. CryllIB2 Aphis spp. CrylllB2 Bemisia tabaci CryllIB2 Empoasca spp. CrylIIB2 Mycus spp. CrylliB2 Nephotettix spp. CrylllB2 Nilaparvata spp. CryllIB2 Pseudococcus spp. CryIlIB2 Psylla spp. CryllIB2 Quadraspidiotus spp. CrylIlB2 Schizaphis spp. CrylIlB2 Trialeurodes spp. CrylllB2 Lyriornyza spp. CrylllB2 Oscinella spp. CryIlIB2 Phorbia spp. CrylllB2 Frankliniella spp. CrylllB2 Thrips spp. CrylllB2 Scirtothrips aurantii CrylllB2 Aceria spp. CrylllB2 Acutus spp.

WO 2008/125245 PCT/EP2008/002759 - 76 AP Control of CrylllB2 Brevipalpus spp. CryIIlB2 Panonychus spp. CrylllB2 Phyllocoptruta spp. CrylllB2 Tetranychus spp. CrylllB2 Heterodera spp. CrylllB2 Meloidogyne spp. CytA Adoxophyes spp. CytA Agrotis spp. CytA Alabama argiilaceae CytA Anticarsia gemmatalis CytA Chilo spp. CytA Clysia ambiguella CytA Crocidolomia binotaiis CytA Cydia spp. CytA Diparopsis castanea CytA Earias spp. CytA Ephestia spp. CytA Heliothis spp. CytA Hellula undalis CytA Keiferia lycopersicella CytA Leucoptera scitelia CytA Lithocollethis spp. CytA Lobesia botrana CytA Ostrinia nubilalis CytA Pandemis spp. CytA Pectinophora gossyp. CytA Phyllocnistis citrella CytA Pieris spp. CytA Plutella xylostella CytA Scirpophaga spp. CytA Sesamia spp. CytA Sparganothis spp. CytA Spodoptera spp.

WO 2008/125245 PCT/EP2008/002759 -77 AP Control of CytA Tortrix spp. CytA Trichoplusia ni CytA Agriotes spp. CytA Anthonomus grandis CytA Curculio spp. CytA Diabrotica balteata CytA Leptinotarsa spp. CytA Lissorhoptrus spp. CytA Otiorhynchus spp. CytA Aleurothrixus spp. CytA Aleyrodes spp. CytA Aonidielia spp. CytA Aphididae spp. CytA Aphis spp. CytA Bemisia tabaci CytA Empoasca spp. CytA Mycus spp. CytA Nephotettix spp. CytA Nilaparvata spp. CytA Pseudococcus spp. CytA Psylla spp. CytA Quadraspidiotus spp. CytA Schizaphis spp. CytA Trialeurodes spp. CytA Lyriomyza spp. CytA Oscinella spp. CytA Phorbia spp. CytA Frankliniella spp. CytA Thrips spp. CytA Scirtothrips aurantii CytA Aceria spp. CytA Acutus spp. CytA Brevipalpus spp.

WO 2008/125245 PCT/EP2008/002759 -78 AP Control of CytA Panonychus spp. CytA Phyllocoptruta spp. CytA Tetranychus spp. CytA Heterodera spp. CytA Meloidogyne spp. VIP3 Adoxophyes spp. VIP3 Agrotis spp. VIP3 Alabama argillaceae VIP3 Anticarsia gemmatalis VIP3 Chilo spp. VIP3 Clysia ambiguella VIP3 Crocidolomia binotalis VIP3 Cydia spp. VIP3 Diparopsis castanea VIP3 Earias spp. VIP3 Ephestia spp. VIP3 Heliothis spp. VIP3 Hellula undalis VIP3 Keiferia lycopersicella VIP3 Leucoptera scitella VIP3 Lithocollethis spp. VIP3 Lobesia botrana VIP3 Ostrinia nubilalis VIP3 Pandemis spp. VIP3 Pectinophora gossyp. VIP3 Phylloenistis citrella VIP3 Pieris spp. VIP3 Piutella xylostella VIP3 Scirpophaga spp. VIP3 Sesamia spp. VIP3 Sparganothis spp. VIP3 Spodoptera spp.

WO 2008/125245 PCT/EP2008/002759 - 79 AP Control of VIP3 Tortrix spp. VIP3 Trichoplusia ni VIP3 Agriotes spp. VIP3 Anthonomus grandis VIP3 Curculio spp. VIP3 Diabrotica balteata VIP3 Leptinotarsa spp. VIP3 Lissorhoptrus spp. VIP3 Otiorhynchus spp. VIP3 Aleurothrixus spp. VIP3 Aleyrodes spp. VIP3 Aonidiella spp. VIP3 Aphididae spp. VIP3 Aphis spp. VIP3 Bemisia tabaci VIP3 Empoasca spp. VIP3 Mycus spp. VIP3 Nephotettix spp. VIP3 Niiaparvata spp, VIP3 Pseudococcus spp. VIP3 Psylla spp. VIP3 Quadraspidiotus spp. VIP3 Schizaphis spp. VIP3 Trialeurodes spp. VIP3 Lyriomyza spp. VIP3 Oscinella spp. VIP3 Phorbia spp. VIP3 Frankliniella spp. VIP3 Thrips spp. VIP3 Scirtothrips aurantii VIP3 Aceria spp. VIP3 Acutus spp. VIP3 Brevipalpus spp.

WO 2008/125245 PCT/EP2008/002759 -80 AP Control of VIP3 Panonychus spp. VIP3 Phyllocoptruta spp. VIP3 Tetranychus spp. VIP3 Heterodera spp. VIP3 Meloidogyne spp. GL Adoxophyes spp. GL Agrotis spp. GL Alabama argillaceae GL Anticarsia gemmatalis GL Chilo spp. GL Clysia ambiguella GL Crocidolomia binotaiis GL Cydia spp. GL Diparopsis castanea GL Earias spp. GL Ephestia spp. GL Heliothis spp. GL Hellula undalis OL Keiferia lycopersicella GL Leucoptera scitella GL Lithocollethis spp. GL Lobesia botrana GL Ostrinia nubilalis GL Pandemis spp. GL Pectinophora gossyp. GL Phyliocnistis citrella GL Pieris spp. GL Plutella xylostella GL Scirpophaga spp. GL Sesamia spp. GL Sparganothis spp. GL Spodoptera spp. GL Tortrix spp.

WO 2008/125245 PCT/EP2008/002759 -81 AP Control of GL Trichoplusia ni GL Agriotes spp. GL Anthonomus grandis GL Curculio spp. GL Diabrotica balteata GL Leptinotarsa spp. GL Lissorhoptrus spp. GL Otiorhynchus spp. GL Aleurothrixus spp. GL Aleyrodes spp. GL Aonidiella spp. CL Aphididae spp. GL Aphis spp. GL Bemisia tabaci GL Empoasca spp. GL Mycus spp. GL Nephotettix spp. GL Nilaparvata spp. GL Pseudococcus spp. GL Psylia spp. GL Quadraspidiotus spp. GL Schizaphis spp. GL Trialeurodes spp. GL Lyriomyza spp. GL Oscinella spp. GL Phorbia spp. GL Frankliniella spp. GL Thrips spp. GL Scirtothrips aurantii GL Aceria spp. GL Aculus spp. GL Brevipalpus spp. GL Panonychus spp.

WO 2008/125245 PCT/EP2008/002759 - 82 AP Control of GL Phyliocoptruta spp. GL Tetranychus spp. GL Heterodera spp. GL Meioidogyne spp. PL Adoxophyesspp. PL Agrotis spp. PL Alabama argillaceae PL Anticarsia gemmatalis PL Chilo spp. PL Clysia ambiguella PL Crocidolomia binotalis PL Cydia spp. PL Diparopsis castanea PL Earias spp. PL Ephestia spp. PL Heliothis spp. PL Hellula undaiis PL Keiferia lycopersicella PL Leucoptera scitella PL Lithocollethis spp. PL Lobesia botrana PL Ostrinia nubilalis PL Pandemis spp. PL Pectinophora gossyp. PL Phyllocnistis citrella PL Pieris spp. PL Plutella xylostella PL Scirpophaga spp. PL Sesamia spp. PL Sparganothis spp. PL Spodoptera spp. PL Tortrix spp. PL Trichoplusia ni WO 2008/125245 PCT/EP2008/002759 -83 AP Control of PL Agriotes spp. PL Anthonomus grandis PL Curculio spp. PL Diabrotica balteata PL Leptinotarsa spp. PL Lissorhoptrus spp. PL Otiorhynchus spp. PL Aleurothrixus spp. PL Aleyrodes spp. PL Aonidiella spp. PL Aphididae spp. PL Aphis spp. PL Bemisia tabaci PL Empoasca spp. PL Mycus spp. PL Nephotettix spp. PL Nilaparvata spp. PL Pseudococcus spp. PL Psylla spp. PL Quadraspidiotus spp. PL Schizaphis spp. PL Trialeurodes spp. PL Lyriomyza spp. PL Oscinella spp. PL Phorbia spp. PL Frankliniella spp. PL Thrips spp. PL Scirtothrips auranii PL Aceria spp. PL Aculus spp. PL Brevipalpus spp. PL Panonychus spp. PL Phyllocoptruta spp.

WO 2008/125245 PCT/EP2008/002759 -84 AP Control of PL Tetranychus spp. PL Heterodera spp. PL Meloidogyne spp. XN Adoxophyes spp. XN Agrotis spp. XN Alabama argiliaceae XN Anticarsia gemmatalis XN Chilo spp. XN Clysia ambiguella XN Crocidolomia binotalis XN Cydia spp. XN Diparopsis castanea XN Earias spp. XN Ephestia spp. XN Heliothis spp. XN Helluia undaiis XN Keiferia lycopersicella XN Leucoptera scitella XN Lithocollethis spp. XN Lobesia botrana XN Ostrinia nubilalis XN Pandemis spp. XN Pectinophora gossyp. XN Phyllocnistis citrella XN Pieris spp. XN Plutella xylostella XN Scirpophaga spp. XN Sesamia spp. XN Sparganothis spp. XN Spodoptera spp. XN Tortrix spp. XN Trichoplusia ni XN Agriotes spp.

WO 2008/125245 PCT/EP2008/002759 - 85 AP Control of XN Anthonomus grandis XN Curculio spp. XN Diabrotica balteata XN Leptinotarsa spp. XN Lissorhoptrus spp. XN Otiorhynchus spp. XN Aleurothrixus spp. XN Aleyrodes spp. XN Aonidiella spp. XN Aphididae spp. XN Aphis spp. XN Bemisia tabaci XN Empoasca spp. XN Mycus spp. XN Nephotettix spp. XN Nilaparvata spp. XN Pseudococcus spp. XN Psylla spp. XN Quadraspidiotus spp. XN Schizaphis spp. XN Trialeurodes spp. XN Lyriomyza spp. XN Oscinella spp. XN Phorbia spp. XN Frankliniella spp. XN Thrips spp. XN Scirtothrips aurantii XN Aceria spp. XN Aculus spp. XN Brevipalpus spp. XN Panonychus spp. XN Phyllocoptruta spp. XN Tetranychus spp.

WO 2008/125245 PCT/EP2008/002759 - 86 AP Control of XN Heterodera spp. XN Meloidogyne spp. Plnh. Adoxophyes spp. Plnh. Agrotis spp. Plnh. Alabama argiliaceae Plnh. Anticarsia gemmatalis Plnh. Chilo spp. Plnh. Clysia ambiguella Plnh. Crocidolomia binotalis Plnh. Cydia spp. Pinh. Diparopsis castanea Plnh. Earias spp. PInh. Ephestia spp. Plnh. Heliothis spp. Pinh. Heliuia undalis Plnh. Keiferia lycopersicella Plnh. Leucoptera scitella Plnh. Lithocollethis spp. Pinh. Lobesia botrana Pinh. Ostrinia nubilalis Pinh. Pandemis spp. Pinh. Pectinophora gossyp. Plnh. Phyllocnistis citrelia Plnh. Pieris spp. Plnh. Plutella xylostella Pinh. Scirpophaga spp. Plnh. Sesamia spp. Plnh. Sparganothis spp. Plnh. Spodoptera spp. Pinh. Tortrix spp. PInh. Trichoplusia ni Plnh. Agriotes spp.

WO 2008/125245 PCT/EP2008/002759 -87 AP Control of Pinh. Anthonomus grandis Pinh. Curculio spp. Pinh. Diabrotica balteata Pinh. Leptinotarsa spp. Plnh. Lissorhoptrus spp. Plnh. Otiorhynchus spp. Plnh. Aleurothrixus spp. Plnh. Aleyrodes spp. Pinh. Aonidiella spp. Pinh. Aphididae spp. Pinh. Aphis spp. Pinh. Bemisia tabaci PInh. Empoasca spp. Pinh. Mycus spp. Plnh. Nephotettix spp. Pinh. Nilaparvata spp. Pinh. Pseudococcus spp. Plnh. Psylla spp. Pinh. Quadraspidiotus spp. Pinh. Schizaphis spp. Pinh. Trialeurodes spp. Pinh. Lyriomyza spp. Pinh. Oscinella spp. Plnh. Phorbia spp. Pinh. Franklinielia spp. Pinh. Thrips spp. Pinh. Scirtothrips aurantii Pinh. Aceria spp. Pinh. Acutus spp. Pinh. Brevipalpus spp. Pinh. Panonychus spp. Pinh. Phyllocoptruta spp. Pinh. Tetranychus spp.

WO 2008/125245 PCT/EP2008/002759 -88 AP Control of Plnh. Heterodera spp. Pinh. Meloidogyne spp. PLec. Adoxophyes spp. PLec. Agrotis spp. PLec. Alabama argillaceae PLec. Anticarsia gemmatalis PLec. Chilo spp. PLec. Clysia ambiguella PLec. Crocidolomia binotalis PLec. Cydia spp. PLec. Diparopsis castanea PLec. Earias spp. PLec. Ephestia spp. PLec. Heliothis spp. PLec. Hellula undalis PLec. Keiferia lycopersicella PLec. Leucoptera scitella PLec. Lithocollethis spp. PLec. Lobesia botrana PLec. Ostrinia nubilalis PLec. Pandemis spp. PLec. Pectinophora gossyp. PLec. Phyllocnistis citrella PLec. Pieris spp. PLec. Plutella xylostella PLec. Scirpophaga spp. PLec. Sesamia spp. PLec. Sparganothis spp. PLec. Spodoptera spp. PLec. Tortrix spp. PLec. Trichoplusia ni PLec. Agriotes spp. PLec. Anthonomus grandis WO 2008/125245 PCT/EP2008/002759 - 89 AP Control of PLec. Curculio spp. PLec. Diabrotica balteata PLec. Leptinotarsa spp. PLec. Lissorhoptrus spp. PLec. Otiorhynchus spp. PLec. Aleurothrixus spp. PLec. Aleyrodes spp. PLec. Aonidiella spp. PLec. Aphididae spp. PLec. Aphis spp. PLec. Bemisia tabaci PLec. Empoasca spp. PLec. Mycus spp. PLec. Nephotettix spp. PLec. Nilaparvata spp. PLec. Pseudococcus spp. PLec. Psylia spp. PLec. Quadraspidiotus spp. PLec. Schizaphis spp. PLec. Trialeurodes spp. PLec. Lyriomyza spp. PLec. Oscinella spp. PLec. Phorbia spp. PLec. Frankliniella spp. PLec. Thrips spp. PLec. Scirtothnps aurantii PLec. Aceria spp. PLec. Aculus spp. PLec. Brevipalpus spp. PLec. Panonychus spp. PLec. Phyllocoptruta spp. PLec. Tetranychus spp. PLec. Heterodera spp.

WO 2008/125245 PCT/EP2008/002759 -90 AP Control of PLec. Meloidogyne spp. Aggl. Adoxophyes spp. Aggl. Agrotis spp. Aggl. Alabama argillaceae Aggl. Anticarsia gernmatalis Aggl. Chilo spp. Aggl. Clysia ambiguella AggL. Crocidolomia binotalis Aggl. Cydia spp. Aggl. Diparopsis castanea Aggl. Earias spp. Aggl. Ephestia spp. Aggl. Heliothis spp. Aggl. lellula undalis Aggl. Keiferia lycopersicella Aggl. Leucoptera scitella Aggl. Lithocollethis spp. Aggl. Lobesia botrana Aggl. Ostrinia nubilalis Aggl. Pandemis spp. Aggl. Pectinophora gossyp. AggL. Phyllocnistis citrella Aggl. Pieris spp. Aggl. Plutiia xylostella Aggl. Scirpophaga spp. Aggl. Sesamia spp. Aggl. Sparganothis spp. Aggi. Spodoptera spp.

WO 2008/125245 PCT/EP2008/002759 -91 AP Control of Aggl. Tortrix spp. Aggl. Trichoplusia ni Aggl. Agriotes spp. Aggl. Anthonomus grandis Aggl. Curculio spp. Aggl. Diabrotica balteata Aggl. Leptinotarsa spp. Aggl. Lissorhoptrus spp. Aggl. Otiorhynchus spp. Aggl. Aleurothrixus spp. Aggl. Aleyrodes spp. Aggl. Aonidiella spp. Aggl. Aphididae spp. Aggl. Aphis spp. Aggl. Bemisia tabaci Aggl. Empoasca spp. Aggl. Mycus spp. Aggl. Nephotettix spp. Aggl. Nilaparvata spp. Aggl. Pseudococcusspp. Aggl. Psylla spp. Aggl. Quadraspidiotus spp. Aggl. Schizaphis spp. Aggl. Trialeurodes spp. Aggl. Lyriomyza spp. Aggl. Oscinella spp. Aggl. Phorbia spp. Aggl. Frankliniella spp. Aggl. Thrips spp. Aggl. Scirtothrips auranti Aggl. Aceria spp. Aggl. Aculus spp. Aggl. Brevipalpus spp.

WO 2008/125245 PCT/EP2008/002759 -92 AP Control of Aggl. Panonychus spp. Aggl. Phyllocoptruta spp Aggl. Tetranychus spp. Aggl. Heterodera spp. Aggl, Meloidogyne spp. CO Adoxophyes spp. CO Agrotis spp. CO Alabama argiliaceae CO Anticarsia gemmatalis CO Chilo spp. CO Ciysia ambiguella CO Crocidolomia binotalis CO Cydia spp. CO Diparopsis castanea CO Earias spp. CO Ephestia spp. CO Heliothis spp. CO Hellula undalis CO Keiferia lycopersicella CO Leucoptera scitella CO Lithocollethis spp. CO Lobesia botrana CO Ostrinia nubilalis CO Pandemis spp. CO Pectinophora gossip. CO Phylloenistis citrella CO Pieris spp. CO Plutella xylostella CO Scirpophaga spp. CO Sesamia spp. CO Sparganothis spp. CO Spodoptera spp. CO Tortrix spp.

WO 2008/125245 PCT/EP2008/002759 - 93 AP Control of CO Trichoplusia ni CO Agriotes spp. CO Anthonomus grandis CO Curculio spp. CO Diabrotica balteata CO Leptinotarsa spp. CO Lissorhoptrus spp. CO Otiorhynchus spp. CO Aleurothrixus spp. CO Aleyrodes spp. CO Aonidielia spp. CO Aphididae spp. CO Aphis spp. CO Bernisia tabaci CO Empoasca spp. CO Mycus spp. CO Nephotettix spp. CO Nilaparvata spp. CO Pseudococcus spp. CO Psylla spp. CO Quadraspidiotus spp. CO Schizaphis spp. CO Trialeurodes spp. CO Lyriomyza spp. CO Oscinella spp. CO Phorbia spp. CO Frankliniella spp. CO Thrips spp. CO Scirtothrips aurantii CO Aceria spp. CO Acutus spp. CO Brevipalpus spp. CO Panonychus spp.

WO 2008/125245 PCT/EP2008/002759 -94 AP Control of CO Phyllocoptruta spp. CO Tetranychus spp. CO Heterodera spp. CO Meloidogyne spp. CH Adoxophyes spp. CH Agrotis spp. CH Alabama argillaceae CH Anticarsia gemmatalis CH Chilo spp. CH Clysia ambiguella CH Crocidolomia binotalis CH Cydia spp. Ci Diparopsis castanea CH Earias spp. CH Ephestia spp. CH Heliothis spp. CH Hellula undalis CH Keiferia lycopersicella CH Leucoptera scitella CH Lithocollethis spp. CH Lobesia botrana CH Ostrinia nubilalis CH Pandemis spp. CH Pectinophora gossyp. CH Phyllocnistis citrella CH Pieris spp. CH Plutella xylostella CH Scirpophaga spp. CH Sesamia spp. CH Sparganothis spp. CH Spodoptera spp. CH Tortrix spp.

WO 2008/125245 PCT/EP2008/002759 - 95 A-P Control of CH Trichoplusia ni CH Agriotes spp. CH Anthonomus grandis CH Curculio spp. CH Diabrotica balteata CH Leptinotarsa spp. CH Lissorhoptrus spp. CH Otiorhynohus spp. CH Aleurothrixus spp. CH Aleyrodes spp. CH Aonidiella spp. CH Aphididae spp. CH Aphis spp. CH Bemisia tabaci CH Empoasca spp. CH Mycus spp. CH Nephotettix spp. CH Nilaparvata spp. CH Pseudococcus spp. CH Psylla spp. CH Quadraspidiotus spp. CH Schizaphis spp. CH Trialeurodes spp. CH Lyriomyza spp. CH Oscinella spp. CH Phorbia spp. CH Frankliniella spp. CH Thrips spp. CH Scirtothrips aurantii CH Aceria spp. CH Aculus spp. CH Brevipalpus spp.

WO 2008/125245 PCT/EP2008/002759 - 96 AP Control of CH Panonychus spp. CH Phyllocoptruta spp. CH Tetranychus spp. CH Heterodera spp. CH Meloidogyne spp. SS Adoxophyes spp. SS Agrotis spp. SS Alabama argillaceae SS Anticarsia gemmatalis SS Chilo spp. SS Clysia ambiguella SS Crocidolomia binotalis SS Cydia spp. SS Diparopsis castanea SS Earias spp. SS Ephestia spp. SS Heliothis spp. SS Hellula undalis SS Keiferia lycopersicella SS Leucoptera scitella SS Lithocollethis spp. SS Lobesia botrana SS Ostrinia nubilalis SS Pandemis spp. SS Pectinophora gossyp, SS Phyllocnistis citrella SS Pieris spp. SS Plutella xylostella SS Scirpophaga spp. SS Sesamia spp. SS Sparganothis spp. SS Spodoptera spp. SS Tortrix spp.

WO 2008/125245 PCT/EP'2008/002759 -97 AP Control of SS Trichopiusia ni SS Agriotes spp. SS Anthonomus grandis SS Curculio spp. SS Diabrotica balteata SS Leptinotarsa spp. SS Lissorhoptrus spp. SS Otiorhynchus spp. SS Aleurothrixus spp. SS Aleyrodes spp. SS Aonidielia spp. SS Aphididae spp. SS Aphis spp. SS Bemisia tabaci SS Empoasca spp. SS Mycus spp. SS Nephotettix spp. SS Nilaparvata spp. SS Pseudococcus spp. SS Psylla spp. SS Quadraspidiotus spp. SS Schizaphis spp. SS Trialeurodes spp. SS Lyriomyza spp. SS Oscinella spp. SS Phorbia spp. SS Frankliniella spp. SS Thrips spp. SS Scirtothrips aurantii SS Aceria spp. SS Aculus spp. SS Brevipalpus spp. SS Panonychus spp.

WO 2008/125245 PCT/EP2008/002759 -98 AP Control of SS Phyllocoptruta spp. SS Tetranychus spp. SS Heterodera spp. SS Meloidogyne spp. HO Adoxophyes spp. HO Agrotis spp. HO Alabama argillaceae HO Anticarsia gemmatalis HO Chilo spp. HO Clysia ambiguella HO Crocidolomia binotalis HO Cydia spp. HO Diparopsis castanea HO Earias spp. HO Ephestia spp. HO Heliothis spp. HO Hellula undalis HO Keiferia lycopersicella HO Leucoptera scitella HO Lithocollethis spp. HO Lobesia botrana HO Ostrinia nubilalis HO Pandemis spp. HO Pectinophora gossypiella HO Phyllocnistis citrella HO Pieris spp. HO Plutella xylostella HO Scirpophaga spp. HO Sesamia spp. HO Sparganothis spp. HO Spodoptera spp. HO Tortrix spp. HO Trichoplusia ni WO 2008/125245 PCT/EP2008/002759 - 99 AP Control of HO Agriotes spp. HO Anthonomus grandis HO Curculio spp. HO Diabrotica balteata HO Leptinotarsa spp. HO Lissorhoptrus spp. HO Otiorhynchus spp. HO Aleurothrixus spp. HO Aleyrodes spp. HO Aonidiella spp. HO Aphididae spp. HO Aphis spp. HO Bemisia tabaci HO Empoasca spp. HO Mycus spp. HO Nephotettix spp. HO Nilaparvata spp. HO Pseudococcus spp. HO Psylla spp. HO Quadraspidiotus spp. HO Schizaphis spp. HO Trialeurodes spp. HO Lyriomyza spp. HO Oscinella spp. HO Phorbia spp. HO Frankliniella spp. HO Thrips spp. HO Scirtothrips aurantii HO Aceria spp. HO Acutus spp. HO Brevipalpus spp. HO Panonychus spp. HO Phyllocoptruta spp.

WO 2008/125245 PCT/EP2008/002759 -100 AP Control of HO Tetranychus spp. HO Heterodera spp. HO Meloidogyne spp.

WO 2008/125245 PCT/EP2008/002759 - 101 Table 3: Abbreviations: acetyl-CoA carboxylase: ACCase acetolactate synthase: ALS 5 hydroxyphenylpyruvate dioxygenase: HPPD inhibition of protein synthesis: IPS hormone imitation: HO glutamine synthetase: GS protoporphyrinogen oxidase: PROTOX 10 5-enolpyruvyl-3-phosphoshikimate synthase: EPSPS Principle Tolerance to Plant ALS sulphonylurea compounds etc.*** cotton ALS sulphonylurea compounds etc.*** rice ALS sulphonylurea compounds etc.*** Brassica ALS sulphonylurea compounds etc.*** potatoes ALS sulphonylurea compounds etc.*** tomatoes ALS sulphonylurea compounds etc.*** pumpkin ALS sulphonylurea compounds etc.*** soya beans ALS sulphonylurea compounds etc.*** maize ALS sulphonylurea compounds etc.*** wheat ALS sulphonylurea compounds etc.*** pome fruit ALS sulphonylurea compounds etc.*** stone fruit ALS sulphonylurea compounds etc.*** citrus fruit ACCase +++ cotton ACCase +++ rice ACCase +++ Brassica ACCase +++ potato ACCase +++ tomatoes ACCase +++ pumpkin ACCase +++ soya beans ACCase +++ maize ACCase +++ wheat ACCase +++ pome fruit ACCase +++ stone fruit WO 2008/125245 PCT/EP2008/002759 -102 Principle Tolerance to Plant ACCase +++ citrus fruit HPPD isoxaflutole, isoxachlortole, sulcotrione, cotton mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, rice mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, Brassica mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, potatoes mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, tomatoes mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, pumpkin mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, soya beans mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, maize mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, wheat mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, pome fruit mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, stone fruit mesotrione HPPD isoxaflutole, isoxachlortole, sulcotrione, citrus fruit mesotrione nitrilase bromoxynil, loxynil cotton nitrilase bromoxynil, loxynil rice nitrilase bromoxynil, loxynil Brassica nitrilase bromoxynil, loxynil potatoes nitrilase bromoxynil, loxynil tomatoes nitrilase bromoxynil, loxynil pumpkin nitrilase bromoxynil, loxynil soya beans nitrilase bromoxynil, loxynil maize nitrilase bromoxynil, loxynil wheat WO 2008/125245 PCT/EP2008/002759 - 103 Principle Tolerance to Plant nitrilase bromoxynil, loxynil pome fruit nitrilase bromoxynil, loxynil stone fruit nitrilase bromoxynil, loxynil citrus fruit IPS chioroactanilides &&& cotton IPS chloroactanilides &&& rice IPS chloroactanilides &&& Brassica IPS chloroactanilides &&& potatoes IPS chloroactanilides &&& tomatoes IPS chioroactanilides &&& pumpkin IPS chloroactanilides &&& soya beans IPS chloroactanilides &&& maize IPS chloroactanilides &&& wheat IPS chloroactanilides &&& pome fruit IPS chloroactanilides &&& stone fruit IPS chloroactanilides &&& citrus fruit HOM 2,4-D, mecoprop-P cotton HOM 2,4-D, mecoprop-P rice HOM 2,4-D, mecoprop-P Brassica HOM 2,4-D, mecoprop-P potatoes HOM 2,4-D, mecoprop-P tomatoes HOM 2,4-D, mecoprop-P pumpkin HOM 2,4-D, mecoprop-P soya beans HOM 2,4-D, mecoprop-P maize HOM 2,4-D, mecoprop-P wheat HOM 2,4-D, mecoprop-P pome fruit HOM 2,4-D, mecoprop-P stone fruit HOM 2,4-D, mecoprop-P citrus fruit PROTOX Protox inhibitors // cotton PROTOX Protox inhibitors // rice PROTOX Protox inhibitors // Brassica PROTOX Protox inhibitors / potatoes PROTOX Protox inhibitors /// tomatoes PROTOX Protox inhibitors /// pumpkin PROTOX Protox inhibitors // soya beans WO 2008/125245 PCT/EP2008/002759 -104 Principle Tolerance to Plant PROTOX Protox inhibitors /// maize PROTOX Protox inhibitors // wheat PROTOX Protox inhibitors // pome fruit PROTOX Protox inhibitors // stone fruit PROTOX Protox inhibitors / citrus fruit EPSPS glyphosate and/or sulphosate cotton EPSPS glyphosate and/or sulphosate rice EPSPS glyphosate and/or sulphosate Brassica EPSPS glyphosate and/or sulphosate potatoes EPSPS glyphosate and/or sulphosate tomatoes EPSPS glyphosate and/or sulphosate pumpkin EPSPS glyphosate and/or sulphosate soya beans EPSPS glyphosate and/or sulphosate maize EPSPS glyphosate and/or sulphosate wheat EPSPS glyphosate and/or sulphosate pome fruit EPSPS glyphosate and/or sulphosate stone fruit EPSPS glyphosate and/or sulphosate citrus fruit GS gluphosinate and/or bialaphos cotton GS gluphosinate and/or bialaphos rice GS gluphosinate and/or bialaphos Brassica GS gluphosinate and/or bialaphos potatoes GS gluphosinate and/or bialaphos tomatoes GS gluphosinate and/or bialaphos pumpkin GS gluphosinate and/or bialaphos soya beans GS gluphosinate and/or bialaphos maize GS gluphosinate and/or bialaphos wheat GS gluphosinate and/or bialaphos pome fruit GS gluphosinate and/or bialaphos stone fruit GS gluphosinate and/or bialaphos citrus fruit *** included are sulphonylurea compounds, imidazolinones, triazolopyrimidines, dimethoxypyrimidines and N-acylsulphonamides: WO 2008/125245 PCT/EP2008/002759 - 105 sulphonylurea compounds such as chlorsulfuron, chlorimuron, ethamethsulfuron, metsulfuron, primisulfuron, prosulfuron, triasulfuron, cinosulfuron, trifusulfuron, oxasulfuron, bensulfuron, tribenuron, ACC 322140, fluzasulfuron, ethoxysulfuron, fluzadsulfuron, nicosulfiron, rimsulfuron, thifensulfuron, pyrazosulfuron, clopyrasulfuron, NC 330, azimsulfuron, imazosulfuron, 5 sulfosulfuron, amidosulfuron, flupyrsulfuron, CGA 362622 imidazolinones such as imazamethabenz, imazaquin, imazamethypyr, imazethapyr, imazapyr and imazamox; triazolopyrimidines such as DE 511, flumetsulam and chloransulam; dimethoxypyrimidines such as, for example, pyrithiobac, pyriminobac, bispyribac and 10 pyribenzoxim. +++ Tolerance to diclofop-methyl, fluazifop-P-butyl, haloxyfop-P-methyl, haloxyfop-P-ethyl, quizalafop-P-ethyl, clodinafop-propargyl, fenoxaprop-ethyl, tepraloxydim, alloxydim, sethoxydim, cycloxydim, cloproxydim, tralkoxydim, butoxydim, caloxydim, clefoxydim, clethodim. &&& chloroacetanilides such as, for example, alachlor, acetochlor, dimethenamid 15 /// Protox inhibitors: for example diphenyl ethers such as, for example, acifluorfen, aclonifen, bifenox, chlornitrofen, ethoxyfen, fluoroglycofen, fomesafen, lactofen, oxyfluorfen; imides such as, for example, azafenidin, carfentrazone-ethyl, cinidon-ethyl, flumiclorac-pentyl, flumioxazin, fluthiacet-methyl, oxadiargyl, oxadiazon, pentoxazone, sulfentrazone, imides and other compounds such as, for example, flumipropyn, flupropacil, nipyraclofen and thidiazimin; and also fluazola and 20 pyraflufen-ethyl.

WO 2008/125245 PCT/EP2008/002759 -106 Table 4 List of examples of transgenic plants having modified properties: Transgenic plants Transgenically modified properties Dianthus caryophyllus (carnation) Longer-lasting as a result of reduced ethylene line 66 accumulation owing to the expression of ACC [Florigene Pty. Ltd.] synthase; tolerant to sulphonylurea herbicides Dianthus caryophyllus (carnation) Modified flower colour; tolerant to sulphonyl lines 4, 11, 15, 16 urea herbicides [Florigene Pty. Ltd.] Dianthus caryophyllus (carnation) Modified flower colour; tolerant to sulphonyl lines 959A, 988A, 1226A, 1351A, 1363A, urea herbicides 1400A [Florigene Pty. Ltd.] Brassica napus (Argentine oilseed rape) Modified fatty acid content in the seeds lines 23-18-17, 23-198 [Monsanto Company] Zea mays L. (maize) Elevated lysine content lines REN-00038-3 (LY038) [Monsanto Company] Zea mays L. (maize) Elevated lysine content, corn borer resistant lines REN-00038-3, MON-00810-6 (MON-00810-6 x LY038) [Monsanto Company] Cucumis melo (melon) Delayed maturity as a result of the expression of lines A, B S-adenosylmethionine hydrolase [Agritope Inc.] WO 2008/125245 PCT/EP2008/002759 -107 Carica papaya (papaya) Resistant to the papaya ring spot virus (PRSV) lines 55-1/63-1 [Cornell University] Solanum tuberosum L. (potato) Resistant to the Colorado beetle and the potato lines RBMT21-129, R.BMT21-350, RBMT22- leaf roll virus (PLRV) 082 [Monsanto Company] Solanum tuberosum L. (potato) Resistant to the Colorado beetle and the potato lines RBMT15-101, SEMT15-02, SEMT15-15 virus Y (PVY) [Monsanto Company] Glycine max L. (soya bean) Modified fatty acid content in the seeds, in lines DD-026005-3 (G94-1, G94-19, G168 particular elevated oleic acid content [DuPont Canada Agricultural Products] Glycine max L. (soya bean) Modified fatty acid content in the seeds, in lines OT96-15 particular reduced linolenic acid content [Agriculture & Agri-Food Canada] Cucurbita pepo (pumpkin) Resistant to viral infections, watermelon mosaic line ZW20 virus (WMV) 2 and zucchini yellow mosaic [Upjohn (USA); Seminis Vegetable Inc. virus (ZYMV) (Canada)] Cucurbita pepo (pumpkin) Resistance to viral infections, cucumber mosaic line CZW-3 virus (CMV), watermelon mosaic virus (WMV) [Asgrow (USA); Seminis Vegetable Inc. 2 and zucchini yellow mosaic virus (ZYMV) (Canada)] Nicotiana tabacum L. (tobacco) Reduced nicotine content line Vector 21-41 [Vector Tobacco] WO 2008/125245 PCT/EP2008/002759 -108 Lycopersicon esculentum (tomato) Longer lasting as a result of reduced ethylene line 1345-4 accumulation owing to the expression of ACC [DNA Plant Technology] synthase Lycopersicon esculentum (tomato) Delayed maturity as a result of the expression of line 35 1 N S-adenosylmethionine hydrolase [Agritope Inc.] Lycopersicon esculentum (tomato) Delayed maturity as a result of the expression of line CGN-89322-3 (8338) ACCd [Monsanto Company] Lycopersicon esculentun (tomato) Delayed softening as a result of a reduced lines B, Da, F expression of polygalacturonase [Zeneca Seeds] Lycopersicon esculentum (tomato) Delayed softening as a result of a reduced line CGN-89564-2 (FLAVR SAVR) expression of polygalacturonase [Calgene Inc.] Throughout this specification and the claims which follow, unless the context requires otherwise, the word "comprise", and variations such as "comprises" or "comprising", will be understood to imply the inclusion of a stated integer or step or group of integers or steps but not the exclusion of any other integer or step or group of integers or steps. The reference in this specification to any piior publication (or information derived from it), or to any matter which is known, is not, and should not be taken as an acknowledgment or admission or any form of suggestion that that prior publication (or information derived from it) or known matter forms part of the common general knowledge in the field of endeavour to which this specification relates.

Claims (12)

1. Method for improving the utilization of the production potential of a transgenic plant, characterized in that the plant is treated with an effective amount of a mixture of at least one compound of the formula I r SHN NH CI Ri 0 NH 5 C 3 where RI represents chlorine or cyano and at least one compound of group II, which comprises imidachioprid, thiodicarb, clothianidin, methiocarb, thiacloprid, thiamethoxam, fipronil, tefluthrin, beta-cyfluthrin, abamectin or spinosad. 10

2. Method according to Claim 1, characterized by a mixture of at least one compound of the formula I and at least one compound of group II.

3. Method according to Claim I or 2, characterized in that the plant has at least one genetically modified structure or a tolerance according to Table 1.

4. Method according to Claim 1 or 2, characterized in that the plant has at least one 15 modified principle of action according to Table 3.

5. Method according to Claim I or 2, characterized in that the plant is a transgenic plant according to Table 4.

6. Method according to Claim I or 2, characterized in that the plant contains at least one genetic modification according to Table 2. 20

7. Method according to Claim I or 2, characterized in that the transgenic plant contains at least one gene or a gene fragment coding for a Bt toxin.

8. Method according to Claim I or 2, characterized in that the transgenic plant is a vegetable plant, maize plant, soya bean plant, cotton plant, tobacco plant, rice plant, sugar WO 2008/125245 PCT/EP2008/002759 -110 beet plant or potato plant.

9. Method according to any of the preceding claims, characterized in that the mixtures of at least one compound of the formula I and at least one compound of group (II) are used for controlling insects from the order Isoptera, Thysanoptera, Homoptera, Heteroptera, 5 Lepidoptera, Coleoptera, Hymenoptera or Diptera.

10. Method according to any of the preceding claims, characterized in that application rates between 0.1 g/ha and 5.0 kg/ha, preferably from 0.1 to 500 g/ha, particularly preferably from 10 to 500 g/ha, especially preferably from 10 to 200 g/ha, are employed.

11. Plant parts, in particular seed or propagation material, of transgenic plants, characterized 10 in that they are obtainable by a method according to any of Claims 1 to 10.

12. Plant parts, in particular seed or propagation material, of transgenic plants, characterized in that they have been treated by a method according to any of Claims 1 to 10.