AU2014233591B2 - Cell line, system and method for optical control of secondary messengers - Google Patents

Cell line, system and method for optical control of secondary messengers

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Publication number
AU2014233591B2
AU2014233591B2 AU2014233591A AU2014233591A AU2014233591B2 AU 2014233591 B2 AU2014233591 B2 AU 2014233591B2 AU 2014233591 A AU2014233591 A AU 2014233591A AU 2014233591 A AU2014233591 A AU 2014233591A AU 2014233591 B2 AU2014233591 B2 AU 2014233591B2
Authority
AU
Australia
Prior art keywords
cell line
optical control
secondary messengers
cell
expressing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2014233591A
Other versions
AU2014233591A1 (en
Inventor
Raag D. Airan
Karl Deisseroth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2009256457A external-priority patent/AU2009256457B2/en
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Priority to AU2014233591A priority Critical patent/AU2014233591B2/en
Publication of AU2014233591A1 publication Critical patent/AU2014233591A1/en
Application granted granted Critical
Publication of AU2014233591B2 publication Critical patent/AU2014233591B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Abstract A method of generating secondary messengers such as cAMP, cGMP, inositol triphosphate and arachidonic acid in a cell, the method comprising modifying a nucleotide sequence for expressing a chimeric light responsive rhodopsin-based membrane protein with one or more heterologous adrenergic receptors alpha 1 and beta2; and expressing the light responsive membrane protein in a cell for producing a secondary messenger in response to light.
AU2014233591A 2008-05-29 2014-09-25 Cell line, system and method for optical control of secondary messengers Ceased AU2014233591B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014233591A AU2014233591B2 (en) 2008-05-29 2014-09-25 Cell line, system and method for optical control of secondary messengers

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61/057,108 2008-05-29
AU2009256457A AU2009256457B2 (en) 2008-05-29 2009-05-29 Cell line, system and method for optical control of secondary messengers
AU2014233591A AU2014233591B2 (en) 2008-05-29 2014-09-25 Cell line, system and method for optical control of secondary messengers

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU2009256457A Division AU2009256457B2 (en) 2008-05-29 2009-05-29 Cell line, system and method for optical control of secondary messengers

Publications (2)

Publication Number Publication Date
AU2014233591A1 AU2014233591A1 (en) 2014-11-06
AU2014233591B2 true AU2014233591B2 (en) 2016-09-22

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Family Applications (1)

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AU2014233591A Ceased AU2014233591B2 (en) 2008-05-29 2014-09-25 Cell line, system and method for optical control of secondary messengers

Country Status (1)

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AU (1) AU2014233591B2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003016486A2 (en) * 2001-08-16 2003-02-27 Sloan Kettering Institute For Cancer Research Bio-synthetic photostimulators and methods of use
US20070261127A1 (en) * 2005-07-22 2007-11-08 Boyden Edward S Light-activated cation channel and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003016486A2 (en) * 2001-08-16 2003-02-27 Sloan Kettering Institute For Cancer Research Bio-synthetic photostimulators and methods of use
US20070261127A1 (en) * 2005-07-22 2007-11-08 Boyden Edward S Light-activated cation channel and uses thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KIM, J-M. et al. Biochemistry, 2005, Vol. 44, Pages 2284-2292 *
MARIN, E.P. et al. J. Biol. Chem. 2000, vol. 275, No. 3 pages 1930-1936. *

Also Published As

Publication number Publication date
AU2014233591A1 (en) 2014-11-06

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired