AU2014200210B2 - Antibodies to IL-6 and use thereof - Google Patents
Antibodies to IL-6 and use thereofInfo
- Publication number
- AU2014200210B2 AU2014200210B2 AU2014200210A AU2014200210A AU2014200210B2 AU 2014200210 B2 AU2014200210 B2 AU 2014200210B2 AU 2014200210 A AU2014200210 A AU 2014200210A AU 2014200210 A AU2014200210 A AU 2014200210A AU 2014200210 B2 AU2014200210 B2 AU 2014200210B2
- Authority
- AU
- Australia
- Prior art keywords
- antibodies
- binding fragments
- association
- fragments
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The present invention is directed to antibodies and fragments thereof having binding specificity for IL-6. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-IL-6 antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-IL-6 antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-IL-6 antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with IL-6. These antibodies may bind at least one of soluble IL-6, cell surface expressed IL-6, IL-6/IL 6R and/or prevent the association of IL-6 and IL-6R, the association of IL-6/IL-6R and gp130 and or the formation of IL-6/IL-6R/gpl3O multimers and thereby inhibit a biological effect associated with any of the foregoing.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2014200210A AU2014200210B2 (en) | 2007-05-21 | 2014-01-14 | Antibodies to IL-6 and use thereof |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60/924,550 | 2007-05-21 | ||
AU2008254584A AU2008254584B2 (en) | 2007-05-21 | 2008-05-21 | Antibodies to IL-6 and use thereof |
AU2014200210A AU2014200210B2 (en) | 2007-05-21 | 2014-01-14 | Antibodies to IL-6 and use thereof |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2008254584A Division AU2008254584B2 (en) | 2007-05-21 | 2008-05-21 | Antibodies to IL-6 and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2014200210A1 AU2014200210A1 (en) | 2014-01-30 |
AU2014200210B2 true AU2014200210B2 (en) | 2016-07-14 |
Family
ID=50001425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2014200210A Active AU2014200210B2 (en) | 2007-05-21 | 2014-01-14 | Antibodies to IL-6 and use thereof |
Country Status (1)
Country | Link |
---|---|
AU (1) | AU2014200210B2 (en) |
-
2014
- 2014-01-14 AU AU2014200210A patent/AU2014200210B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2014200210A1 (en) | 2014-01-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NB | Applications allowed - extensions of time section 223(2) |
Free format text: THE TIME IN WHICH TO MAKE A FURTHER APPLICATION FOR A DIVISIONAL PATENT HAS BEEN EXTENDED TO 03 FEB 2014 . |
|
PC1 | Assignment before grant (sect. 113) |
Owner name: ALDERBIO HOLDINGS LLC Free format text: FORMER APPLICANT(S): BRISTOL-MYERS SQUIBB COMPANY; ALDERBIO HOLDINGS LLC |
|
FGA | Letters patent sealed or granted (standard patent) | ||
PC | Assignment registered |
Owner name: H. LUNDBECK A/S Free format text: FORMER OWNER(S): ALDERBIO HOLDINGS LLC |
|
PC | Assignment registered |
Owner name: VITAERIS INC. Free format text: FORMER OWNER(S): H. LUNDBECK A/S |