AU2013263786B2 - Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases - Google Patents
Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseasesInfo
- Publication number
- AU2013263786B2 AU2013263786B2 AU2013263786A AU2013263786A AU2013263786B2 AU 2013263786 B2 AU2013263786 B2 AU 2013263786B2 AU 2013263786 A AU2013263786 A AU 2013263786A AU 2013263786 A AU2013263786 A AU 2013263786A AU 2013263786 B2 AU2013263786 B2 AU 2013263786B2
- Authority
- AU
- Australia
- Prior art keywords
- diseases
- disorders
- treatment
- cell
- various diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 10
- 201000010099 disease Diseases 0.000 title abstract 8
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000019491 signal transduction Effects 0.000 title 1
- 108010055717 JNK Mitogen-Activated Protein Kinases Proteins 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 229940118135 JNK inhibitor Drugs 0.000 abstract 1
- 239000012825 JNK inhibitor Substances 0.000 abstract 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 208000004631 alopecia areata Diseases 0.000 abstract 1
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 abstract 1
- 108091006116 chimeric peptides Proteins 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000024963 hair loss Diseases 0.000 abstract 1
- 230000003676 hair loss Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000003909 protein kinase inhibitor Substances 0.000 abstract 1
- 230000011664 signaling Effects 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
- 210000004291 uterus Anatomy 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention refers to the use of protein kinase inhibitors and more specifically to the use of inhibitors of the protein kinase c-Jun amino terminal kinase, JNK inhibitor sequences, chimeric peptides, or of nucleic acids encoding same as well as pharmaceutical compositions containing same, for the treatment of various diseases, or disorders strongly related to JNK signalling, wherein these diseases or disorders are selected from autoimmune disorders, cardiovascular diseases, cancerous diseases, diabetes, including diabetes type 1 or type 2, inflammatory diseases, hair loss, including Alopecia areata, diseases of the lung, neuronal or neurodegenerative diseases, diseases of the liver, diseases of the spine, diseases of the uterus, viral infectious diseases and depressive disorders.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2013263786A AU2013263786B2 (en) | 2008-05-30 | 2013-11-28 | Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPCT/EP2008/004341 | 2008-05-30 | ||
AU2009253346A AU2009253346B2 (en) | 2008-05-30 | 2009-06-02 | Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases |
AU2013263786A AU2013263786B2 (en) | 2008-05-30 | 2013-11-28 | Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2009253346A Division AU2009253346B2 (en) | 2008-05-30 | 2009-06-02 | Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2013263786A1 AU2013263786A1 (en) | 2013-12-19 |
AU2013263786B2 true AU2013263786B2 (en) | 2016-07-14 |
Family
ID=49760114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2013263786A Ceased AU2013263786B2 (en) | 2008-05-30 | 2013-11-28 | Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases |
Country Status (1)
Country | Link |
---|---|
AU (1) | AU2013263786B2 (en) |
-
2013
- 2013-11-28 AU AU2013263786A patent/AU2013263786B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU2013263786A1 (en) | 2013-12-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FGA | Letters patent sealed or granted (standard patent) | ||
MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |