AU2013250814B2 - Rodent Plasmodium parasites as platforms for a whole-organism malaria vaccine - Google Patents

Rodent Plasmodium parasites as platforms for a whole-organism malaria vaccine Download PDF

Info

Publication number
AU2013250814B2
AU2013250814B2 AU2013250814A AU2013250814A AU2013250814B2 AU 2013250814 B2 AU2013250814 B2 AU 2013250814B2 AU 2013250814 A AU2013250814 A AU 2013250814A AU 2013250814 A AU2013250814 A AU 2013250814A AU 2013250814 B2 AU2013250814 B2 AU 2013250814B2
Authority
AU
Australia
Prior art keywords
plasmodium
human
rodent
organism
stage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU2013250814A
Other languages
English (en)
Other versions
AU2013250814A1 (en
Inventor
Antonio Manuel Barbeiro Mendes
Maria Manuel DIAS DA MOTA
Rui Miguel Prudencio Pignatelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instituto de Medicina Molecular Joao Lobo Antunes
Original Assignee
Instituto de Medicina Molecular Joao Lobo Antunes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto de Medicina Molecular Joao Lobo Antunes filed Critical Instituto de Medicina Molecular Joao Lobo Antunes
Publication of AU2013250814A1 publication Critical patent/AU2013250814A1/en
Application granted granted Critical
Publication of AU2013250814B2 publication Critical patent/AU2013250814B2/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/58Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2013250814A 2012-04-17 2013-04-17 Rodent Plasmodium parasites as platforms for a whole-organism malaria vaccine Expired - Fee Related AU2013250814B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT106262 2012-04-17
PT10626212 2012-04-17
PCT/IB2013/053050 WO2013156949A1 (en) 2012-04-17 2013-04-17 Rodent plasmodium parasites as platforms for a whole-organism malaria vaccine

Publications (2)

Publication Number Publication Date
AU2013250814A1 AU2013250814A1 (en) 2014-12-04
AU2013250814B2 true AU2013250814B2 (en) 2017-03-02

Family

ID=48539330

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013250814A Expired - Fee Related AU2013250814B2 (en) 2012-04-17 2013-04-17 Rodent Plasmodium parasites as platforms for a whole-organism malaria vaccine

Country Status (10)

Country Link
US (1) US9655957B2 (enExample)
EP (1) EP2838554B1 (enExample)
JP (1) JP6096884B2 (enExample)
CN (1) CN104302313B (enExample)
AU (1) AU2013250814B2 (enExample)
BR (1) BR112014025823A8 (enExample)
IN (1) IN2014MN02275A (enExample)
PT (1) PT2838554T (enExample)
WO (1) WO2013156949A1 (enExample)
ZA (1) ZA201408440B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104771752B (zh) * 2015-04-21 2018-01-05 中国人民解放军第三军医大学 疟疾红内期灭活全虫疫苗的新用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005063991A2 (en) * 2003-12-19 2005-07-14 Seattle Biomedical Research Institute Live genetically attenuated malaria vaccine
WO2006062928A2 (en) * 2004-12-03 2006-06-15 Seattle Biomedical Research Institute Live genetically engineered protozoan vaccine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2978048B1 (fr) * 2011-07-20 2014-10-10 Univ Paris Curie Composition vaccinale contre le paludisme

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005063991A2 (en) * 2003-12-19 2005-07-14 Seattle Biomedical Research Institute Live genetically attenuated malaria vaccine
WO2006062928A2 (en) * 2004-12-03 2006-06-15 Seattle Biomedical Research Institute Live genetically engineered protozoan vaccine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MUELLER A. et al, Genetically modified Plasmodium parasites as a protective experimental malaria vaccine, Nature, 2005, Vol. 433, pg. 164-167 *

Also Published As

Publication number Publication date
JP6096884B2 (ja) 2017-03-15
WO2013156949A1 (en) 2013-10-24
EP2838554A1 (en) 2015-02-25
EP2838554B1 (en) 2018-08-22
US9655957B2 (en) 2017-05-23
ZA201408440B (en) 2015-12-23
BR112014025823A8 (pt) 2017-07-25
BR112014025823A2 (enExample) 2017-06-20
CN104302313B (zh) 2018-01-26
HK1206243A1 (en) 2016-01-08
IN2014MN02275A (enExample) 2015-08-07
US20150071966A1 (en) 2015-03-12
JP2015514745A (ja) 2015-05-21
AU2013250814A1 (en) 2014-12-04
PT2838554T (pt) 2018-11-23
CN104302313A (zh) 2015-01-21

Similar Documents

Publication Publication Date Title
de Jong et al. Immunity against sexual stage Plasmodium falciparum and Plasmodium vivax parasites
Goh et al. Vaccination with sporozoites: models and correlates of protection
Duffy et al. Pre-erythrocytic malaria vaccines: identifying the targets
Miura Progress and prospects for blood-stage malaria vaccines
Vaughan et al. Genetically engineered, attenuated whole-cell vaccine approaches for malaria
Acharya et al. Host–parasite interactions in human malaria: clinical implications of basic research
Carvalho et al. Malaria vaccine: candidate antigens, mechanisms, constraints and prospects
Chandley et al. Host-parasite interactions during Plasmodium infection: Implications for immunotherapies
Matuschewski et al. Vaccines against malaria–an update
Hassert et al. Memory CD8+ T cell‐mediated protection against liver‐stage malaria
Mikolajczak et al. Preerythrocytic malaria vaccine development
Vijayan et al. Development of blood stage malaria vaccines
Quagliata et al. Malaria vaccines
Ravetch et al. Molecular genetic strategies for the development of anti-malarial vaccines
AU2013250814B2 (en) Rodent Plasmodium parasites as platforms for a whole-organism malaria vaccine
US20210353731A1 (en) Doubly attenuated late liver stage malaria parasites and related compositions and methods
Manuel Rodent Plasmodium parasites as platforms for a whole-organism malaria vaccine
Ngulube Humoral Immune Responses to P. falciparum Circumsporozoite Protein (Pfcsp) Induced by the RTS, S Vaccine–Current Update
Serrano‐Coll et al. Plasmodium and Host Immunity: Evasion Strategies and Advances in Malaria Vaccination
Nicholas III Preliminary Characterization and Functional Validation of Pre-erythrocytic Vaccine Candidates for the Malaria Parasite Plasmodium vivax
HK1206243B (en) Rodent plasmodium parasites as platforms for a whole-organism malaria vaccine
TADDESE Status in Malaria Vaccine Development: Basic aspects of Vaccinology mechanism of actions, vaccine pipelines, stage oriented immune response ‘Challenges and Opportunities’
Bigeard Development of in vitro models for the study of the human CD8 T cell response to Plasmodium liver stage
Mo et al. NIAID meeting report: improving malaria vaccine strategies through the application of immunological principles
Bergmann-Leitner et al. The impact of immune responses on the asexual erythrocytic stages of plasmodium and the implication for vaccine development

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application