AU2013201292A1 - Cereal composition comprising high-potency sweetener - Google Patents

Cereal composition comprising high-potency sweetener Download PDF

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AU2013201292A1
AU2013201292A1 AU2013201292A AU2013201292A AU2013201292A1 AU 2013201292 A1 AU2013201292 A1 AU 2013201292A1 AU 2013201292 A AU2013201292 A AU 2013201292A AU 2013201292 A AU2013201292 A AU 2013201292A AU 2013201292 A1 AU2013201292 A1 AU 2013201292A1
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sweet taste
composition
taste improving
cereal
acid
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AU2013201292A
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Grant E. Dubois
Indra Prakash
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Coca Cola Co
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Coca Cola Co
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Priority claimed from AU2006318708A external-priority patent/AU2006318708B2/en
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Abstract

The present invention relates generally to cereal compositions comprising non-caloric or low-caloric high-potency sweeteners and methods for making and using them. In particular, the present invention relates to different cereal compositions comprising at least one non-caloric or 5 low-caloric natural and/or synthetic high potency sweetener and at least one sweet taste improving composition. The present invention also relates to cereal compositions and methods that can improve the tastes of non-caloric or low-caloric natural and/or synthetic, high-potency sweeteners by imparting a more sugar-like taste or characteristic. In particular, the cereal compositions and methods provide a more sugar-like temporal profile, including sweetness 10 onset and sweetness linger, and/or a more sugar-like flavor profile.

Description

AUSTRALIA Patents Act COMPLETE SPECIFICATION (ORIGINAL) Class Int. Class Application Number: Lodged: Complete Specification Lodged: Accepted: Published: Priority Related Art: Name of Applicant: The Coca-Cola Company Actual Inventor(s): Indra Prakash, Grant E. Dubois Address for Service and Correspondence: PHILLIPS ORMONDE FITZPATRICK Patent and Trade Mark Attorneys 367 Collins Street Melbourne 3000 AUSTRALIA Invention Title: CEREAL COMPOSITION COMPRISING HIGH-POTENCY SWEETENER Our Ref: 964323 POF Code: 513846/78750 The following statement is a full description of this invention, including the best method of performing it known to applicant(s): -1la CEREAL COMPOSITION COMPRISING HIGH-POTENCY SWEETENER The present application is a divisional application from Australian Patent Application No. 20063 18708, the entire disclosure of which is incorporated herein by reference. FIELD OF THE INVENTION 5 The present invention relates generally to novel cereal compositions, including functional cereals, comprising non-caloric or low-caloric natural and/or synthetic high-potency sweeteners and methods for manufacture and use thereof. The present invention also relates to cereal compositions and methods that can improve the taste of cereal compositions comprising non caloric or low-caloric natural and/or synthetic high-potency sweeteners by imparting a more 10 sugar-like taste. BACKGROUND OF THE INVENTION Natural caloric sugars, such as sucrose, fructose, and glucose are utilized heavily in beverage, food, pharmaceutical, and oral hygienic/cosmetic industries due to their pleasant taste. In particular, sucrose imparts a desirable taste for consumers. Although sucrose provides 15 superior sweetness characteristics, it is caloric. While calories are necessary for proper bodily functions, there is a need in the market to provide alternative non-caloric or low-caloric sweeteners with sugar-like taste for consumers with sedentary lifestyles or those who are calorie conscious. However, in general, non-caloric or low caloric sweeteners have associated undesirable tastes to consumers such as delayed sweetness onset; lingering sweet aftertaste; 20 bitter taste; metallic taste; astringent taste; cooling taste; licorice-like taste; and/or the like. For example, the sweet tastes of natural and/or synthetic high-potency sweeteners are slower in onset and longer in duration than the sweet taste produced by sugar and thus change the taste balance of a food composition. Because of these differences, use of a natural high potency sweetener to replace a bulk sweetener, such as sugar, in a food or beverage, causes an 25 unbalanced temporal profile and/or flavor profile. In addition to the difference in temporal profile, high-potency sweeteners generally exhibit (i) lower maximal response than sugar, (ii) off tastes including bitter, metallic, cooling, astringent, licorice-like taste, etc., and/or (iii) sweetness which diminishes on iterative tasting. It is well known to those skilled in the art of food/beverage formulation that changing the sweetener in a composition requires re-balancing 30 of the flavor and other taste components (e.g., acidulants). If the taste profile of natural and synthetic high-potency sweeteners could be modified to impart specific desired taste characteristics to be more sugar-like, the type and variety of compositions that may be prepared with that sweetener would be significantly expanded.
2 Accordingly, it would be desirable to selectively modify the taste characteristics of natural and synthetic high-potency sweeteners. The discussion of documents, acts, materials, devices, articles and the like is included in this specification solely for the purpose of providing a context for the present invention. It is 5 not suggested or represented that any or all of these matters formed part of the prior art base or were common general knowledge in the field relevant to the present invention as it existed before the priority date of each claim of this application. Where the terms "comprise", "comprises", "comprised" or "comprising" are used in this specification (including the claims) they are to be interpreted as specifying the presence of the 10 stated features, integers, steps or components, but not precluding the presence of one or more other features, integers, steps or components, or group thereof. SUMMARY OF THE INVENTION Generally, this invention addresses the above described need by providing a cereal composition having improved temporal profile and/or flavor profile, a method for improving the 15 temporal profile and/or flavor profile, a cereal composition having improved temporal profile and/or flavor profile, and a method for improving the temporal profile and/or flavor profile for cereals. In particular, this invention improves the temporal profile and/or flavor profile by imparting a more sugar-like temporal profile and/or flavor profile. More particularly, this invention comprises a cereal composition comprising at least one high-potency sweetener, at 20 least one sweet taste improving composition, and at least one cereal ingredient. Aspects and advantages of the invention will be set forth in part in the following description, or may be obvious from the description, or may be learned through practice of the invention. Unless otherwise defined, all technical and scientific terms and abbreviations used herein have the same meaning as commonly understood by one of ordinary skill in the art to 25 which this invention pertains. Although methods and compositions similar or equivalent to those described herein can be used in practice of the present invention, suitable methods and compositions are described without intending that any such methods and compositions limit the invention herein. BRIEF DESCRIPTION OF THE DRAWINGS 30 Fig. I is a powder x-ray diffraction scan of rebaudioside A polymorph Form I on a plot of the scattering intensity versus the scattering angle 20 in accordance with an embodiment of this invention.
WO 2007/061908 PCTIUS2006/044798 3 Fig. 2 is a powder x-ray diffraction scan of rebaudioside A polymorph Form 2 on a plot of the scattering intensity versus the scattering angle 20 in accordance with an embodiment of this invention. Fig. 3 is a powder x-ray diffraction scan of rebaudioside A polymorph Form 3A on 5 a plot of the scattering intensity versus the scattering angle 20 in accordance with an embodiment of this invention. Fig. 4 is a powder x-ray diffraction scan of rebaudioside A polymorph Form 3B on a plot of the scattering intensity versus the scattering angle 20 in accordance with an embodiment of this invention. 10 Fig. 5 is a powder-x-ray diffraction scan of rebaudioside A polymorph Form 4 on a plot of the scattering intensity versus the scattering angle 20 in accordance with an embodiment of this invention. DETAILED DESCRIPTION OF THE INVENTION Reference now will be made in detail to the presently proffered embodiments of 15 the invention. Each example is provided by way of explanation of embodiments of the invention, not limitation of the invention. In fact, it will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the invention. For instance, features illustrated or described as part of one embodiment, can be used on another embodiment to yield a still 20 further embodiment. Thus, it is intended that the present invention cover such modifications and variations within the scope of the appended claims and their equivalents. Generally described, embodiments of the present invention provide cereal compositions comprising at least one natural and/or synthetic high-potency sweetener, at 25 least one sweet taste improving composition, and at least one cereal ingredient. As used herein the phrase "the at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving composition" is synonymous with the phrase "the sweetener composition." WO 2007/061908 PCT/US2006/044798 4. I. Cereal Compositions Cereal compositions typically are eaten either as staple foods or as snacks. Non limiting examples of cereal compositions for use in particular embodiments include ready to-eat cereals as well as hot cereals. Ready-to-eat cereals are cereals which may be eaten 5 without further processing (i.e. cooking) by the consumer. Examples of ready-to-eat cereals include breakfast cereals and snack bars. Breakfast cereals typically are processed to produce a shredded, flaky, puffy, or extruded form. Breakfast cereals generally are eaten cold and are often mixed with milk and/or fruit. Snack bars include, for example, energy bars, rice cakes, granola bars, and nutritional bars. Hot cereals generally are 10 cooked, usually in either milk or water, before being eaten. Non-limiting examples of hot cereals include grits, porridge, polenta, rice, and rolled oats. Cereal compositions generally comprise at least one cereal ingredient. As used herein, the term "cereal ingredient" denotes materials such as whole or part grains, whole or part seeds, and whole or part grass. Non-limiting examples of cereal ingredients for use 15 in particular embodiments include maize, wheat, rice, barley, bran, bran endosperm, bulgur, soghums, millets, oats, rye, triticale. buchwheat, fonio, quinoa, bean, soybean, amaranth, teff, spelt, and kaniwa. In a particular embodiment, the cereal composition comprises at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste 20 improving composition and at least one cereal ingredient. The sweetener composition may be added to the cereal composition in a variety of ways. For example, the sweetener composition may be added to the cereal composition as a coating, as a-frosting, as a glaze, or as a matrix blend (i.e. added as an ingredient to the cereal -formulation prior to the preparation of the final cereal product). 25 Accordingly, in a particular embodiment, the at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving composition is added to the cereal composition as a matrix blend. In one embodiment, the sweetener composition is blended with a hot cereal prior to cooking to provide a sweetened hot cereal product. In another embodiment, the sweetener composition is 30 blended with the cereal matrix before the cereal is extruded.
WO 2007/061908 PCTIUS2006/044798 5 In another particular embodiment, the at least one natural and/or synthetic high potency sweetener in combination with at least one sweet taste improving composition is added to the cereal composition as a coating. In one embodiment, the sweetener composition is added as a coating by combining the sweetener composition with a food 5 grade oil and applying the mixture onto the cereal. In a different embodiment, the sweetener composition and the food grade oil may be applied to the cereal separately, either by applying first the oil and then the sweetener composition, or by applying first the sweetener composition and then the oil. Non-limiting examples of food grade oils for use in particular embodiments include vegetable oils such as corn oil, soybean oil, cottonseed 10 oil, peanut oil, coconut oil, canola oil, olive oil, sesame seed oil, palm oil, palm kernel oil, and mixtures thereof. In yet another embodiment, food grade fats may be used in place of the oils, provided that the fat is melted prior to applying the fat onto the cereal. In another embodiment, the at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving composition is added to 15 the cereal composition as a glaze. In one such embodiment, the sweetener composition is added as a glaze by combining the sweetener composition with a glazing agent and applying the mixture to the cereal. Non-limiting examples of glazing agents for use in particular embodiments include corn syrup, honey syrups and honey syrup solids, maple syrups and maple syrup solids, sucrose, isomalt, polydextrose, polyols, hydrogenated 20 starch hydrosylate, aqueous solutions thereof, and mixtures thereof. In another such embodiment, the sweetener composition is added as a glaze by combining the sweetener composition with a glazing agent and a food grade oil or fat and applying the mixture to the cereal. In yet another embodiment, a gum system, such as, for example, gum acacia, carboxymethyl cellulose, or algin, may be added to the glaze to provide structural support. 25 In addition, the glaze also may include a coloring agent, and also may include a flavor. In another embodiment, the at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving composition is added to the cereal composition as a frosting. In one such embodiment, the sweetener composition is added as a frosting by combining the sweetener composition with water and a frosting 30 agent and then applying the mixture to the cereal. Non-limiting examples of frosting agents for use in particular embodiments include maltodextrin, sucrose, starch, polyols, WO 2007/061908 PCT/US2006/044798 6 and mixtures thereof. The frosting also may include a food grade oil, a food grade fat, a coloring agent, and/or a flavor. Generally, the amount of the at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving composition in a cereal composition 5 varies widely depending on the particular type of cereal composition and its desired sweetness. Those of ordinary skill in the art can readily discern the appropriate amount of sweetener to put in the cereal composition. In a particular embodiment, the at least one natural and/or synthetic high-potency sweetener is present in the cereal composition in an amount in the range of about 0.02 to about 1.5 weight percent of the cereal composition 10 and the at least one sweet taste improving composition is present in the cereal composition in an amount in the range of about 1 to about 5 weight percent of the cereal composition. II. Sweetener Compositions As described hereinabove, the cereal compositions comprise at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving 15 composition. The combination of the at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving composition, as used herein, comprises the "sweetener composition." As used herein, a cereal ingredient is synonymous with a "sweetenable composition." In addition, the combination of the sweetener composition and a cereal ingredient comprises a "sweetened composition." 20 A. Natural High-Potency Sweeteners Desirably, the sweetener composition comprises at least one natural and/or synthetic high-potency sweetener. As used herein the phrases "natural high-potency sweetener", "NHPS", "NHPS composition", and "natural high-potency sweetener composition" are synonymous. "NHPS" means any sweetener found in nature which may 25 be in raw, extracted, purified, or any other form, singularly or in combination thereof and characteristically have a sweetness potency greater than sucrose, fructose, or glucose, yet have less calories. Non-limiting examples of NHPSs suitable for embodiments of this invention include rebaudioside A, rebaudioside B, rebaudioside C, rebaudioside D, rebaudioside E, rebaudioside F, dulcoside A, dulcoside B, rubusoside, stevia, stevioside, 30 mogroside IV, mogroside V, Luo Han Guo sweetener, siamenoside, monatin and its salts WO 2007/061908 PCT/US2006/044798 7 (monatin SS, RR, RS, SR), curculin, glycyrrhizic acid and its salts, thaumatin, monellin, mabinlin, brazzein, hemandulcin, phyllodulcin, glycyphyllin, phloridzin, trilobatin, baiyunoside, osladin, polypodoside A, pterocaryoside A, pterocaryoside B, mukurozioside, phlomisoside 1, periandrin I, abrusoside A, and cyclocarioside 1. NHPS 5 also includes modified NHPSs. Modified NHPSs include NHPSs which have been altered naturally. For example, a modified NHPS includes, but is not limited to, NHPSs which have been fermented, contacted with enzyme, or derivatized or substituted on the NHPS. In one embodiment, at least one modified NHPS may be used in combination with at least one NHPS. In another embodiment, at least one modified NHPS may be used without a 10 NHPS. Thus, modified NHPSs may be substituted for a NHPS or may be used in combination with NHPSs for any of the embodiments described herein. For the sake of brevity, however, in the description of embodiments of this invention, a modified NHPS is not expressly described as an alternative to an unmodified NHPS, but it should be understood that modified NHPSs can be substituted for NHPSs in any embodiment 15 disclosed herein. Purity, as used here, represents the weight percentage of a respective NHPS compound present in a NIHPS extract, in raw or purified form. In one embodiment, a steviolglycoside extract comprises a particular steviolglycoside in a particular purity, with the remainder of the stevioglycoside extract comprising a mixture of other 20 steviolglycosides. To obtain a particularly pure extract of a NHPS, such as rebaudioside A, it may be necessary to purify the crude extract to a substantially pure form. Such methods generally are known to those of ordinary skill in the art. An exemplary method for purifying a NHPS, such as rebaudioside A, is described 25 in the co-pending patent application no. 60/805,216, entitled "Rebaudioside A Composition and Method for Purifying Rebaudioside A," filed on June 19, 2006, by inventors DuBois, et al., the disclosure of which is incorporated herein by reference in its entirety. Briefly described, substantially pure rebaudioside A is crystallized in a single step 30 from an aqueous organic solution comprising at least one organic solvent and water in an WO 2007/061908 PCT/US2006/044798 8 amount from about 10 % to about 25 % by weight, more particularly from about 15 % to about. 20 % by weight. Organic solvents desirably comprise alcohols, acetone; and. acetonitile. Non-limiting examples of alcohols include ethanol, methanol, isopranol, 1 propanol, 1-butanol, 2-butanol, tert-butanol, and isobutanol. Desirably, the at least one 5 organic solvent comprises a mixture of ethanol and methanol present in the aqueous' organic solution in a weight ratio ranging from about 20 parts to about 1 part ethanol to 1 part methanol; more desirably from about 3 parts to about 1 part ethanol to 1 part methanol. Desirably, the weight ratio of the aqueous organic solvent and crude rebaudioside 10 A ranges from about 10 to about 4 parts aqueous organic solvent to 1 part crude rebaudioside A, more particularly from about 5 to about 3 parts aqueous organic solvent to 1 part crude rebaudioside A. In an exemplary embodiment, the method of purifying rebaudioside A is carried out at approximately room temperature. In another embodiment, the method of purifying 15 rebaudioside A further comprises the step of heating the rebaudioside A solution to a temperature in a range from about 20'C to about 40C, or in another embodiment to a reflux temperature, for about 0.25 hours to about 8 hours. In another exemplary embodiment,. wherein the method for purifying rebaudioside A comprises the step of heating the rebaudioside A solution, the method further comprises the step of cooling the 20 rebaudioside A solution to a temperature in the range from about 4'C to about 25'C for about 0.5 hours to about 24 hours. According to particular embodiments, the purity of rebaudioside A may range from about 50% to about 100%; from about 70% to about 100%; from about 80% to about 100%; from about 90% to about 100%; from about 95% to about 100%; from about 95% 25 to about 99.5%; about 96% to about 100%; from about 97% to about 100%; from about 98% to about 100%; and from about 99% to about 100%. According to particularly desirable embodiments, upon crystallization of crude rebaudioside A, the substantially pure rebaudioside A composition comprises rebaudioside A in a purity greater than about 95 % by weight up to about 100% by weight on a dry basis. In other exemplary 30 embodiments, substantially pure rebaudioside A comprises purity levels of rebaudioside A WO 2007/061908 PCTIUS2006/044798 9 greater than about 97 % up to about 100% rebaudioside A by weight on a dry basis, greater than about 98 % up to about 100% by weight on a dry basis, or greater than about 99 % up to about 100% by weight on a dry basis. The rebaudioside A solution during the single crystallization step may be stirred or unstirred. 5 In an exemplary embodiment, the method of purifying rebaudioside A further comprises the step of seeding (optional step) the rebaudioside A solution at an appropriate temperature with high-purity crystals of rebaudioside A sufficient to promote crystallization of the rebaudioside A to form pure rebaudioside A. ' An amount of rebaudioside A sufficient to promote crystallization of substantially pure rebaudioside A 10 comprises an amount of rebaudioside A from about 0.0001 % to about 1 % by weight of the rebaudioside A present in the solution, more particularly from about 0.01 % to about 1 % by weight. An appropriate temperature for the step of seeding comprises a temperature in a range from about 18*C to about 35'C. In another exemplary embodiment, the method of purifying rebaudioside A further 15 comprises the steps of separating and washing the substantially pure rebaudioside A composition. The substantially pure rebaudioside A composition may be separated from the aqueous organic solution by a variety of solid-liquid separation techniques that utilize centrifugal force, that include, without limitation, vertical and horizontal perforated basket centrifuge, solid bowl centrifuge, decanter centrifuge, peeler type centrifuge, pusher type 20 centrifuge, Heinkel type centrifuge, disc stack centrifuge and cyclone separation. Additionally, separation may be enhanced by any of pressure, vacuum, and gravity filtration methods, that include, without limitation, the use of belt, drum, nutsche type, leaf, plate, Rosenmund type, sparkler type, and bag filters and filter press. Operation of the rebaudioside A solid-liquid separation device may be continuous, semi-continuous or in 25 batch mode. The substantially pure rebaudioside A composition also may be washed on the separation device using various aqueous organic solvents and mixtures thereof. The substantially pure rebaudioside A composition can be dried partially or totally on the separation device using any number of gases, including, without limitation, nitrogen and argon, to evaporate residual liquid solvent. The substantially pure rebaudioside A 30 composition may be removed automatically or manually from the separation device using WO 2007/061908 PCT/US2006/044798 10 liquids, gases or mechanical means by either dissolving the solid or maintaining the solid form. In still another exemplary embodiment, the method of purifying rebaudioside A further comprises the step of drying the substantially pure rebaudioside A composition 5 using techniques well known to those skilled in the art, non-limiting examples of which include the use of a rotary vacuum dryer, fluid bed dryer, rotary tunnel dryer, plate dryer, tray dryer, Nauta type dryer, spray dryer, flash dryer, micron dryer, pan dryer, high and low speed paddle dryer and microwave dryer. In an exemplary embodiment, the step of drying comprises drying the substantially pure rebaudioside A composition using a 10 nitrogen or argon purge to remove the residual solvent at a temperature in a range from about 40'C to about 60'C for about 5 hours to about 100 hours. In yet another exemplary embodiment, wherein the crude rebaudioside A mixture comprises substantially no rebaudioside D impurity, the method of purifying rebaudioside A further comprises the step of slurrying the composition of substantially pure 15 rebaudioside A with an aqueous organic solvent prior to the step of drying the substantially pure rebaudioside A composition. The slurry is a mixture comprising a solid and an aqueous organic or organic solvent, wherein the solid comprises the substantially pure rebaudioside A composition and is only sparingly soluble in the aqueous organic or organic solvent. In an embodiment, the substantially pure rebaudioside A composition 20 and aqueous organic solvent are present in the slurry in a weight ratio ranging from about 15 parts to 1 part aqueous organic solvent to 1 part substantially pure rebaudioside A composition. In one embodiment, the slurry is maintained at room temperature. In another embodiment, the step of slurrying comprises heating the slurry to a temperature in a range from about 20 to about 40'C. The substantially pure rebaudioside A composition 25 is slurried for about 0.5 hours to about 24 hours. In still yet another exemplary embodiment, the method of purifying rebaudioside A further comprises the steps of separating the substantially pure rebaudioside A composition from the aqueous organic or organic solvent of the slurry and washing the substantially pure rebaudioside A composition followed by the step of drying the 30 substantially pure rebaudioside*A composition.
WO 2007/061908 PCT/US20061044798 11 If further purification is desired, the method.of purifying rebaudioside A described herein may be repeated or the substantially pure rebaudioside A composition may be purified further using an alternative purification method, such as the column chromatography. 5 It also is contemplated that other NHPSs may be purified using the purification method described herein, requiring only minor experimentation that would be obvious to those of ordinary skill in the art. The purification of rebaudioside A by crystallization as described above results in the formation of at least four different polymorphs: Form 1: a rebaudioside A hydrate; 10 Form 2: an anhydrous rebaudioside A; Form 3: a rebaudioside A solvate; Form 4: an amorphous rebaudioside A. The aqueous organic solution and temperature of the purification process influence the resulting polymorphs in the substantially pure rebaudioside A composition. Figures 1-5 are exemplary powder x-ray diffraction (XRPD) scans of polymorphs Form 1 (hydrate), Form 2 (anhydrate), Form 3A (methanol solvate), 15 Form 3B (ethanol solvate), and Form 4 (amorphous), respectively. The material properties of the four rebaudioside A polymorphs are summarized in the following table: Table 1: Rebaudioside A Polymorphs Form 1 Form 2 Form 3 Form 4 Polymorph Polymorph Polymorph Polymorph Rate of dissolution Very low (<0.2 Intermediate (<30 High (> 30 % /5 High (> 35 % /5 in H20 at 25*C %/60 minutes) %15 minutes) minutes) minutes) Alcohol content < 0.5 % < 1 % 1-3 % Moisture content >5 % < 1 % < 3 % 6.74 % ~ 20 The type of polymorph formed is dependent on the composition of the aqueous organic solution, the temperature of the crystallization step, and the temperature during the drying step. Form 1 and Form 3 are formed during the single crystallization step while Form 2 is formed during the drying step after conversion from Form 1 or Form 3. Low temperatures during the crystallization step, in the range of about 20'C to 25 about 50'C, and a low ratio of water to the organic solvent in the aqueous organic solvent results in the formation of Form 3. High temperatures during the crystallization step, in WO 2007/061908 PCT/US2006/044798 12 the range of about 50'C to about 80'C, and a high ratio of water to the organic solvent in the aqueous organic solvent results in the formation of the Form 1. Form 1 can be converted to Form 3 by scurrying in an anhydrous solvent at room temperature (2 -16 hours) or at reflux for approximately (0.5-3 hours).. Form 3 can be converted to Form 1 by 5 slurrying the polymorph in water at room temperature for approximately 16 hours or at reflux for approximately 2-3 hours. Form 3 can be converted to the Form 2 during the drying process; however,* increasing either the drying temperature above 70C or the drying time of a substantially pure rebaudioside A composition can result in decomposition of the rebaudioside A and increase the remaining rebaudioside B impurity 10 in the substantially pure rebaudioside A composition. Form 2 can be converted to Form 1 with the addition of water. Form 4 may be formed from Form 1, 2, 3, or combinations thereof, using methods well known to those of ordinary skill in the art. Non-limiting examples of such methods include melt-processing, ball milling, crystallization, lyophilization, cryo-grinding, and 15 spray-drying. In a particular embodiment, Form 4 can be prepared from a substantially pure rebaudioside A composition obtained by the purification methods described hereinabove by spray-drying a solution of the substantially pure rebaudioside A composition. B. Synthetic High-Potency Sweeteners 20 As used herein, the phrase "synthetic sweetener" refers to any compositions which are not found in nature and characteristically have a sweetness potency greater than sucrose, fructose, or glucose, yet have less calories. Non-limiting examples of synthetic sweeteners suitable for embodiments of this invention include sucralose, potassium acesulfame, aspartame, alitame, saccharin, neohesperidin dihydrochalcone, cyclamate, 25 neotame, N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl]-L-a-aspartyl]-L-phenylalanine 1 methyl ester, N-[N-[3-(3-hydroxy-4-methoxyphenyl)-3-methylbutyl-L-a-aspartyl]-L phenylalanine 1-methyl ester, N-[N-[3-(3-methoxy-4-hydroxyphenyl)propyl)-L-a aspartyl]-L-phenylalanine 1-methyl ester, salts thereof, and the like. 30 WO 2007/061908 PCT/US2006/044798 13 C. Combinations of Natural and/or Synthetic High-Potency Sweeteners The NHPS and synthetic sweeteners may be used individually or in combination with other NHPS and/or synthetic sweeteners. For example, the sweetener composition may comprise a single NHPS or a single synthetic sweetener; a single NHPS in 5 combination with a single synthetic sweetener; one or more NHPSs in combination with a single synthetic sweetener; a single NHPS in combination with one or nore synthetic sweeteners; or one or more NHPSs in combination with one or more synthetic sweeteners. A plurality of natural and/or synthetic high-potency sweeteners may be used as long as the combined effect does not adversely affect the taste of the sweetener composition. 10 For example, particular embodiments comprise combinations of NHPSs, such as. steviolglycosides. Non-limiting examples of suitable stevioglycosides which may be combined include rebaudioside A, rebaudioside B, rebaudioside C, rebaudioside D, rebaudioside E, rebaudioside F, dulcoside A, dulcoside B, rubusoside, stevioside, or steviolbioside. According to particularly desirable embodiments of the present invention, 15 the combination of high-potency sweeteners comprises rebaudioside A in combination with rebaudioside B, rebaudioside C, rebaudioside E, rebaudioside F, stevioside, steviolbioside, dulcoside A, or combinations thereof. Generally, according to a particular embodiment, rebaudioside A is present in the combination of high-potency sweeteners in an amount in the range of about 50 to about 20 99.5 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 70 to about 90 weight percent, and still more desirably in the range of about 75 to about 85 weight percent. In another particular embodiment, rebaudioside B is present in the combination of high-potency sweeteners in an amount in the range of about 1 to about 8 weight percent of 25 the combination of high-potency sweeteners, more desirably in the range of about 2 to about 5 weight percent, and still more desirably in the range of about 2 to about 3 weight percent. In another particular embodiment, rebaudioside C is present in the combination of high-potency sweeteners in an amount in the range of about 1 to about 10 weight percent 30 of the combination of high-potency sweeteners, more desirably in the range of about 3 to WO 2007/061908 PCT/US2006/044798 14 about 8 weight percent, and still more desirably in the range of about 4 to about 6 weight percent. In still another particular embodiment, rebaudioside E is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 5 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about 1 weight percent. In still another particular embodiment, rebaudioside F is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 weight 10 percent of the combination of high-potency sweeteners, more desirably in the range of about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about 1 weight percent. In still yet another particular embodiment, dulcoside A is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 15 weight percent of the combination of high-potency sweeteners, more desirably in the range of about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about 1 weight percent. In yet another particular embodiment, dulcoside B is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 weight percent 20 of the combination of high-potency sweeteners, more desirably in the range of about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about 1 weight percent. In another particular embodiment, stevioside is present in the combination of high potency sweeteners in an amount in the range of about 0.5 to about 10 weight percent of 25 the combination of high-potency sweeteners, more desirably in the range of about 1 to about 6 weight percent, and still more desirably in the range of about 1 to about 4 weight percent. In still another particular embodiment, steviolbioside is present in the combination of high-potency sweeteners in an amount in the range of about 0.1 to about 4 weight 30 percent of the combination of high-potency sweeteners, more desirably in the range of WO 2007/061908 PCT/US2006/044798 15 about 0.1 to about 2 weight percent, and still more desirably in the range of about 0.5 to about 1 weight percent. According to a particularly desirable embodiment, the high-potency sweetener composition comprises a combination of rebaudioside A, stevioside, rebaudioside B, 5 rebaudioside C, and rebaudioside F; wherein rebaudioside A is present in the combination of high-potency sweeteners in an amount in the range of about 75 to about 85 weight percent based on the total weight of the combination of high-potency sweeteners, stevioside is present in an amount in the range of about 1 to about 6 weight percent, .rebaudioside B is present in an amount in the range of about 2 to about 5 weight percent, 10 rebaudioside C is present in an amount in the range of about 3 to about 8 weight percent, and rebaudioside F is present in an amount in the range of about 0.1 to about 2 weight percent. In addition, those of ordinary skill in the art should appreciate that the sweetener composition can be customized to obtain a desired calorie content. For example, a low 15 caloric or non-caloric NHPS may be combined with a caloric natural sweetener and/or other caloric additives to produce a sweetener composition with a preferred calorie content. III. Sweet Taste Improving Compositions The sweetener composition also comprises a sweet taste improving composition, 20 non-limiting examples of which include carbohydrates, polyols, amino acids and their corresponding salts, polyamino acids and their corresponding salts, sugar acids and their corresponding salts, nucleotides, organic acids, inorganic acids, organic salts including organic acid salts and organic base salts, inorganic salts, bitter compounds, flavorants and flavoring ingredients, astringent compounds, proteins or protein hydrolysates, surfactants, 25 emulsifiers, flavonoids, alcohols, polymers, other sweet taste improving taste additives imparting such sugar-like characteristics, and combinations thereof. In one embodiment, a single sweet taste improving composition may be used in combination with a single natural and/or synthetic high-potency sweetener. In another embodiment of the present invention, a single sweet taste improving composition may be 30 used in combination with one or more natural and/or synthetic high-potency sweeteners.
WO 2007/061908 PCT/US2006/044798 16 In yet another embodiment, one or more sweet taste improving compositions may be.used in combination with a single natural and/or synthetic high-potency sweetener. In a further embodiment, there may be a plurality of sweet taste improving combinations used in combination with one or more natural and/or synthetic high-potency sweeteners. 5 In a particular. embodiment, combinations of at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving composition. suppress, reduce, or eliminate undesirable taste and impart sugar-like characteristics to the sweetener composition. As used herein, the phrase "undesirable taste" includes any taste property which is not imparted by sugars, e.g. glucose, sucrose, fructose, or similar 10 saccharides. Non-limiting examples of undesirable tastes include delayed sweetness onset, lingering sweet aftertaste, metallic taste, bitter taste, cooling sensation taste or menthol-like taste, licorice-like taste, and/or the like. A. Sweet Taste In one embodiment, a sweetener composition exhibits a more sugar-like temporal 15 and/or sugar-like flavor profile than a sweetener composition comprising at least one natural and/or synthetic high-potency sweetener, but without a sweet taste improving composition is provided. As used herein, the phrases "sugar-like characteristic," "sugar like taste," "sugar-like sweet," "sugary," and "sugar-like" are synonymous. Sugar-like characteristics include any characteristic similar to that of sucrose and include, but are not 20 limited to, maximal response, flavor profile, temporal profile, adaptation behavior, mouthfeel, concentration/response function behavior, tastant and flavor/sweet taste interactions, spatial pattern selectivity, and temperature effects. These characteristics are dimensions in which the taste of sucrose is different from the tastes of natural and synthetic high-potency sweeteners. Whether or not a characteristic is more sugar-like is 25 determined by expert sensory panel assessments of sugar and compositions comprising at least one natural and/or synthetic high-potency sweetener, both with and without a sweet taste improving composition. Such assessments quantify similarities of the characteristics of compositions comprising at least one natural and/or synthetic high-potency sweetener, both with and without a sweet taste improving composition, with those comprising sugar.
WO 2007/061908 PCT/US2006/044798 17 Suitable procedures for determining whether a composition has a more sugar-like taste are well known in the art. In a particular embodiment, a panel of assessors is used to measure the reduction of sweetness linger. .Briefly described, a panel of assessors (generally 8 to. 12 individuals) is 5 trained to evaluate sweetness perception and measure sweetness at several time points from when the sample is initially taken. into the mouth until 3 minutes after it has been expectorated. Using statistical analysis, the results are compared between samples containing additives and samples that do not contain additives. A decrease in score for a time point measured after the sample has cleared the mouth indicates there has been a 10 reduction in sweetness perception. The panel of assessors may be trained using procedures well known to those of ordinary skill in the art. In a particular embodiment, the panel of assessors may be trained using the SpectrumTM Descriptive Analysis Method (Meilgaard et al, Sensory Evaluation Techniques, 3 edition, Chapter 11). Desirably, the focus of training should be the 15 recognition of and the measure of the basic tastes; specifically, sweet. In order to ensure accuracy and reproducibility of results, each assessor should repeat the measure of the reduction of sweetness linger about three to about five times per sample, taking at least a five minute break between each repetition and/or sample and rinsing well with water to clear the mouth. 20 Generally, the method of measuring sweetness comprises taking a 10mL sample into the mouth, holding the sample in the mouth for 5 seconds and gently swirling the sample in the mouth, rating the sweetness intensity perceived at 5 seconds, expectorating the sample (without swallowing following expectorating the sample), rinsing with one mouthful of water (e.g., vigorously moving water in mouth as if with mouth wash) and 25 expectorating the rinse. water, rating the sweetness intensity perceived immediately upon expectorating the rinse water, waiting 45 seconds and, while wating those 45 seconds, identifying the time of maximum perceived sweetness intensity and rating the sweetness intensity at that time (moving the mouth normally and swallowing as needed), rating the sweetness intensity after another 10 seconds, rating the sweetness intensity after another 30 60 seconds (cumulative 120 seconds after rinse), and rating the sweetness intensity after WO 2007/061908 PCT/US2006/044798 18 still another 60 seconds (cumulative 180 seconds after rinse). Between samples take a 5 minute break, rinsing well with water to clear the mouth. B. Types of Sweet Taste Improving Compositions As described hereinabove, sweet taste. improving compositions include 5 carbohydrates, polyols, amino acids and their corresponding salts, polyamino acids and their corresponding salts, sugar acids and their corresponding salts, nucleotides, organic acids, inorganic acids,. organic salts including organic acid salts and organic base salts, inorganic salts, bitter compounds, flavorants and flavoring ingredients, astringent compounds, proteins or protein hydrolysates, surfactants, emulsifiers, flavonoids, alcohols, 10 polymers, other sweet taste improving taste additives imparting such sugar-like characteristics, and combinations thereof. As used herein, the term "carbohydrate" generally refers to aldehyde or ketone compounds substituted with multiple hydroxyl groups, of the general formula (CH 2 )., wherein n is 3-30, as well as their oligomers and polymers. The carbohydrates of the 15 present invention can, in addition, be substituted or deoxygenated at one or more positions. Carbohydrates, as used herein, encompass unmodified carbohydrates, carbohydrate derivatives, substituted carbohydrates, and modified. carbohydrates. As used herein, the phrases "carbohydrate derivatives", "substituted carbohydrate", and "modified carbohydrates" are synonymous. Modified carbohydrate means any carbohydrate wherein 20 at least one atom has been added, removed, substituted, or combinations thereof. Thus, carbohydrate derivatives or substituted carbohydrates include substituted and unsubstituted monosaccharides, disaccharides, oligosaccharides, and polysaccharides. The carbohydrate derivatives or substituted carbohydrates optionally can be deoxygenated at any corresponding C-position, and/or substituted with one -or more moieties such as 25 hydrogen, halogen, haloalkyl, carboxyl, acyl, acyloxy, amino, amido, carboxyl derivatives, alkylamino, dialkylamino, arylamino, alkoxy, aryloxy, nitro, cyano, sulfo, mercapto, imino, sulfonyl, sulfenyl, sulfinyl, sulfamoyl, carboalkoxy, carboxamido, phosphonyl, phosphinyl, phosphoryl, phosphino, thioester, thioether, oximino, hydrazino, carbaryl, phospho, phosphonato, or any other viable functional group provided the carbohydrate WO 2007/061908 PCT/US2006/044798 19 derivative or substituted carbohydrate functions to improve the sweet' taste of the sweetener composition. Non-limiting examples of carbohydrates in embodiments of this invention include tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., o.-cyclodextrin, r 5 cyclodextrin, and y-cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, erythrulose, xylulose, psicose, turanose, cellobiose, amylopectin, glucosamine, 10 mannosamine, fucose, glucuronic acid, gluconic- acid, glucono-lactone, abequose, galactosamine, beet oligosaccharides, isomalto-oligosaccharides (isomaltose, isomaltotriose, panose and the like), xylo-oligosaccharides (xylotriose, xylobiose and the like), gentio-oligoscaccharides (gentiobiose, gentiotriose, gentiotetraose -and the like), sorbose, nigero-oligosaccharides, palatinose oligosaccharides, fructooligosaccharides 15 (kestose,. nystose and the like), maltotetraol, maltotriol, malto-oligosaccharides (maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose and the like), lactulose, melibiose, raffinose, rhamnose, ribose, isomerized liquid sugars such as high fructose corn/starch syrup (e.g., HFCS55, HFCS42, HFCS90), coupling sugars,. soybean oligosaccharides, and glucose syrup. Additionally, the carbohydrates as used herein may 20 be. in either the D- or L- configuration. The term "polyol", as used herein, refers to a molecule that contains more than one hydroxyl group. A polyol may be a diol, triol, or a tetraol which contain 2, 3, and 4 hydroxyl groups, respectively. A polyol also may contain more than four hydroxyl groups, such as a pentaol, hexaol, heptaol, or the like, which contain, 5, 6, or 7 hydroxyl 25 groups, respectively. Additionally, a polyol also may be a sugar alcohol, polyhydric alcohol, or polyalcohol which is a reduced form of carbohydrate, wherein the carbonyl group (aldehyde or ketone, reducing sugar) has been reduced to a primary or secondary hydroxyl group. . Non-limiting examples of sweet taste improving polyol additives in embodiments 30 of this invention include erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, WO 2007/061908 PCTIUS2006/044798 20 isomalt, propylene glycol, glycerol (glycerine), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo-oligosaccharides, reduced gentio oligosaccharides, reduced maltose syrup, reduced glucose syrup, and sugar alcohols or any other carbohydrates capable of being reduced which do not adversely affect the taste of the 5 sweetener composition. Suitable sweet taste improving amino acid additives for use in embodiments of this invention include, but are not limited to, aspartic acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, valine, tyrosine, leucine, isoleucine, asparagine, serine, lysine, histidine, ornithine, methionine, camitine, aminobutyric acid 10 (alpha-, beta-, or gamma- isomers), glutamine, hydroxyproline, taurine, norvaline, sarcosine, and their salt forms such as sodium or potassium salts or acid salts. The sweet taste improving amino acid additives also may be in the D- or L- configuration and in the mono-, di-, or tri- form of the same or different amino acids. Additionally, the amino acids may be a-, P-, -f-, 8-, and e- isomers if appropriate. Combinations of the foregoing 15 amino acids and their corresponding salts (e.g., sodium, potassium, calcium, magnesium salts or other alkali or alkaline .earth metal salts thereof, or acid salts) also are suitable sweet taste improving additives in embodiments of this invention. The amino acids may be natural or synthetic. The amino acids also may be modified. Modified amino acids refers to any amino acid wherein at least one atom has been added, removed, substituted, 20 or combinations thereof (e.g., N-alkyl amino acid, N-acyl amino acid, or N-methyl amino acid). Non-limiting examples of modified amino .acids include amino acid derivatives such as trimethyl glycine, N-methyl-glycine, and N-methyl-alanine. As used herein, amino acids encompass both modified and unmodified amino acids. As used herein, modified amino acid also may encompass peptides and polypeptides (e.g., dipeptides, 25 tripeptides, tetrapeptides, and pentapeptides) such as glutathione and L-alanyl-L glutamine. Suitable sweet taste improving polyamino acid additives include pdly-L-aspartic acid, poly-L-lysine (e.g., poly-L-a-lysine or poly-L-s-lysine), poly-L-ornithine (e.g., poly L-a-ornithine or poly-L-e-ornithine), poly-L-arginine, other polymeric forms of amino 30 acids, and salt forms thereof (e.g., magnesium, calcium, potassium, or sodium salts such as L-glutamic acid mono sodium salt). The sweet taste improving polyamino acid additives WO 2007/061908 PCT/US2006/044798 21 also may be in the D- or L- configuration. Additionally, the polyamino acids may be a-, p-, y-, 6-, and e- isomers if appropriate. Combinations of the foregoing polyamino acids and their corresponding salts (e.g., sodium, potassium, calcium, magnesium salts or other alkali or alkaline earth metal salts thereof or acid salts) also are suitable sweet taste 5 improving additives in embodiments of this invention. The polyamino acids described herein also may comprise co-polymers of different amino acids. The polyamino acids may be natural or synthetic. The polyamino acids also may be modified, such that at least one atom has been added, removed, substituted, or combinations thereof (e.g., N-alkyl polyamino acid or N-acyl polyamino acid). As used herein, polyamino acids encompass 10 both modified and unmodified polyamino acids. In accordance with particular embodiments, modified polyamino acids include, but are not limited to polyamino acids of various molecular weights (MW), such as poly-L-a-lysine with a MW of 1,500, MW of 6,000, MW of 25,200, MW of 63,000, MW of 83,000, or MW of 300,000. Suitable sweet taste improving sugar acid additives for use in embodiments of this 15 invention include, but are not limited to, aldonic, uronic, aldaric, alginic, gluconic, glucuronic, glucaric, galactaric, galacturonic, and their salts (e.g., sodium, potassium, calcium, magnesium salts or other physiologically acceptable salts), and combinations thereof. Suitable sweet taste improving nucleotide additives for use in embodiments of this 20 invention include, but are not limited to, inosine monophosphate ("IMP"), guanosine monophosphate ("GMP"), adenosine monophosphate ("AMP"), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, 25 and their alkali or alkaline earth metal salts, and combinations thereof. The nucleotides described herein also may comprise nucleotide-related additives, such as nucleosides or nucleic acid bases (e.g., guanine, cytosine, adenine, thymine, uracil). Suitable sweet taste improving organic acid additives include any compound which comprises a -COOH moiety. Suitable sweet taste improving organic acid additives for 30 use in embodiments of this invention include, but are not limited to, C2-C30 carboxylic WO 2007/061908 PCT/US2006/044798 22 acids, substituted hydroxyl CI-C30 carboxylic acids, benzoic acid, substituted benzoic acids (e.g. 2,4-dihydroxybenzoic acid), substituted cinnamic acids, hydroxyacids, substituted hydroxybenzoic acids, substituted cyclohexyl carboxylic acids, tannic acid, lactic acid, tartaric acid, citric acid, gluconic acid, glucoheptonic acids, adipic acid, 5 hydroxycitric acid, malic acid, fruitaric acid (a blend of malic, fumaric, and tartaric acids), fumaric acid, maleic acid, succinic acid, chlorogenic acid, salicylic acid,. creatine, glucosamine hydrochloride, glucono delta lactone, caffeic acid, bile acids, acetic acid, ascorbic acid, alginic acid, erythorbic acid, polyglutamic acid, and their alkali or alkaline earth metal salt derivatives thereof. In addition, the sweet taste improving organic acid 10 additives also may be in either the D-: or L- configuration. Suitable sweet taste improving organic acid salt additives include, but are not limited to, sodium, calcium, potassium, and magnesium salts of all organic acids, such as salts of citric acid, malic acid, tartaric acid, fumaric acid, lactic acid (e.g., sodium lactate), alginic acid (e.g., sodium alginate), ascorbic acid (e.g., sodium ascorbate), benzoic acid 15 (e.g., sodium benzoate or potassium benzoate), and adipic acid. The examples of the sweet taste improving organic acid salt additives described optionally may be substituted with one or more of the following moiety selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, halo, haloalkyl, carboxyl, acyl, acyloxy, amino, amido, carboxyl derivatives, alkylamino, dialkylamino, arylamino, alkoxy, aryloxy, nitro, cyano, sulfo, 20 thiol, imine, sulfonyl, sulfenyl, sulfinyl, sulfamyl, carboxalkoxy, carboxamido, phosphonyl, phosphinyl, phosphoryl, phosphino, thioester, thioether, anhydride, oximino, hydrazino, carbaryl, phospho, phosphonato, and any other viable functional group, provided the substituted organic acid salt additive functions to improve the sweet taste of the sweetener composition. 25 Suitable sweet taste improving inorganic acid additives for use in embodiments of this invention include, but are not limited to, phosphoric acid, phosphorous acid, polyphosphoric acid, hydrochloric acid, sulfuric acid, carbonic acid, sodium dihydrogen phosphate, and their corresponding alkali or alkaline earth metal salts thereof (e.g., inositol hexaphosphate Mg/Ca).
WO 2007/061908 PCT/US2006/044798 23 Suitable sweet taste improving bitter compound additives for. use in embodiments of this invention include, but are not limited to, caffeine, quinine, urea, bitter orange oil, naringin, quassia, and salts thereof. Suitable sweet taste improving flavorant and flavoring ingredient additives for use 5 in embodiments of this invention include, but are not limited to, vanillin, vanilla extract, mango extract, cinnamon, citrus, coconut, ginger, viridiflorol, almond, menthol (including menthol without mint), grape skin extract, and grape seed extract. "Flavorant" and "flavoring ingredient" are synonymous, and include natural or synthetic substances or combinations thereof. Flavorants also include any other substance which imparts flavor, 10 and may include natural or non-natural (synthetic) substances which are safe for human or animals when used in a generally accepted range. Non-limiting examples of proprietary flavorants include D6herTM Natural Flavoring Sweetness Enhancer K14323 (D6hlerTM, Darmstadt, Germany), SymriseTm Natural Flavor Mask for Sweeteners 161453. and 164126 (Symrise, HolzmindenTM, Germany), Natural Advantage T M Bitterness Blockers 1, 15 2, 9 and 10 (Natural AdvantageTM, Freehold, New Jersey, U.S.A.), and SucramaskTM (Creative Research Management, Stockton, Califomia, U.S.A.). Suitable sweet taste improving polymer additives for use in embodiments of this invention include, but are not limited to, chitosan, pectin, pectic, pectinic, polyuronic, polygalacturonic acid, starch, food hydrocolloid or crude extracts thereof (e.g., gum acacia 20 senegal (Fibergumm), gum acacia seyal, carageenan), poly-L-lysine (e.g., poly-L-a-lysine or poly-L-E-lysine), poly-L-omithine (e.g., poly-L-a-omithine or poly-L-e-omithine), polyarginine, polypropylene glycol, polyethylene glycol, poly(ethylene glycol methyl ether), polyaspartic acid, polyglutamic acid, polyethyleneimine, alginic acid, sodium alginate, propylene glycol alginate, sodium hexametaphosphate (SHMP) and its salts, and 25 sodium polyethyleneglycolalginate and other cationic and anionic polymers. Suitable sweet taste improving protein or protein hydrolysate additives for use in embodiments of this invention include, but are not limited to, bovine serum albumin (BSA), whey protein (including fractions or concentrates thereof such as 90% instant whey protein isolate, 34% whey protein, 50%. hydrolyzed whey protein, and 80% whey 30 protein concentrate), soluble rice protein, soy protein, protein isolates, protein WO 2007/061908 PCT/US20061044798 24 hydrolysates, reaction products of protein hydrolysates, glycoproteins, and/or proteoglycans containing amino acids (e.g., glycine, alanine, serine, threonine, asparagine, glutamine, arginine, valine, isoleucine, leucine, norvaline, methionine, praline, tyrosine, hydroxyproline, and the like), collagen (e.g., gelatin), partially hydrolyzed collagen (e.g., 5 hydrolyzed fish collagen), and collagen hydrolysates (e.g., porcine collagen hydrolysate). Suitable sweet taste improving surfactant additives for use in embodiments of this invention include, but are not limited to,. polysorbates (e.g., polyoxyethylene sorbitan monooleate (polysorbate 80), polysorbate 20, polysorbate 60), sodium dodecylbenzenesulfonate, dioctyl sulfosuccinate or dioctyl sulfosuccinate sodium, sodium 10 dodecyl sulfate, cetylpyridinium chloride (hexadecylpyridinium chloride), hexadecyltrimethylammonium bromide, sodium cholate, carbamoyl, choline chloride, sodium glycocholate, sodium taurodeoxycholate, lauric arginate, sodium stearoyl lactylate, sodium taurocholate, lecithins, sucrose oleate esters, sucrose stearate esters, sucrose palmitate esters, sucrose laurate esters, and other emulsifiers, and the like. 15 Suitable sweet taste improving flavonoid additives for use in embodiments of this invention generally are classified as flavonols, flavones, flavanones, flavan-3-ols, isoflavones, or anthocyanidins. Non-limiting examples of flavonoid additives include catechins (e.g., green tea extracts such as PolyphenonTM 60, PolyphenonTM 30, and PolyphenonTm 25 (Mitsui Norin Co., Ltd., Japan), polyphenols, rutins (e.g., enzyme 20 modified rutin SanmelinTm AO (San-Ei Gen F.F.I., Inc., Osaka, Japan)), neohesperidin, naringin, neohesperidin dihydrochalcone, and the like. Suitable sweet taste improving alcohol additives for use in embodiments of this invention include, but are not limited to, ethanol. Suitable sweet taste improving astringent compound additives include, but are not 25 limited to, tannic acid, europium chloride (EuCl 3 ), gadolinium chloride (GdCIA), terbium chloride (TbCI 3 ), alum, tannic acid, and polyphenols (e.g., tea polyphenols). Suitable sweet taste improving vitamins include nicotinamide (Vitamin B3) and pyridoxal hydrochloride (Vitamin B6). The sweet taste improving compositions also may comprise natural and/or 30 synthetic high-potency sweeteners. For example, wherein. the sweetener composition WO 2007/061908 PCT/US2006/044798 25 comprises at least one NHPS, the at least one sweet taste improving composition -may comprise a synthetic high-potency sweetener, -non-limiting examples of which include sucralose, potassium acesulfame, aspartame, alitame, saccharin, neohesperidin dihydrochalcone, cyclamate, neotame, N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl)-L 5 a-aspartyl]-L-phenylalanine 1-methyl ester, N-[N-[3-(3-hydroxy-4-methoxyphenyl)-3 methylbutyl]-L-a-aspartyll-L-phenylalanine 1-methyl ester, N-[N-[3-(3-methoxy-4 hydroxyphenyl)propyl]-L-ci-aspartyl)-L-phenylalanine 1-methyl ester, salts thereof, and the like. The sweet taste improving compositions also may be in salt form which may be 10 obtained using standard procedures well known in the art. The term "salt" also refers to complexes that retain the desired chemical activity of the sweet taste improving compositions of the present invention and are safe for human or animal consumption in a generally acceptable range. Alkali metal (for example, sodium or potassium) or alkaline earth metal (for example, calcium or magnesium) salts also can be made. Salts also may 15 include combinations of alkali and alkaline earth metals. Non-limiting examples of such salts are (a) acid addition salts formed with inorganic acids and salts formed with organic acids; (b) base addition salts formed with metal cations such as calcium, bismuth, barium, magnesium, aluminum, copper, cobalt, nickel, cadmium, sodium, potassium, arid the like, or with a cation formed from ammonia, N,N-dibenzylethylenediamine, D-glucosamine, 20 tetraethylammonium, or ethylenediamine; or (c) combinations of (a) and (b). Thus, any salt forms which may be derived from the sweet taste improving compositions may be used with the embodiments of the present invention as long as the salts of the sweet taste improving additives do not adversely affect the taste of the sweetener compositions comprising the at least one natural and/or synthetic high-potency sweetener. The salt 25 forms of the additives can be added to the natural and/or synthetic sweetener composition in the same amounts as their acid or base forms. In particular embodiments, suitable sweet taste improving inorganic salts useful as sweet taste improving additives include, but are not limited to, sodium chloride, potassium chloride, sodium sulfate, potassium citrate, europium chloride (EuCl 3 ), gadolinium 30 chloride* (GdCl 3 ), terbium chloride (TbC1 3 ), magnesium sulfate, alum, magnesium chloride, mono-, di-, tri-basic sodium or potassium salts of phosphoric acid (e.g., inorganic WO 2007/061908 PCT/US2006/044798 26 phosphates), salts of hydrochloridic acid (e.g., inorganic chlorides),. sodium carbonate, sodium bisulfate, and sodium bicarbonate. Furthermore, in particular embodiments, suitable organic salts useful as sweet taste improving additives include, but are not limited to, choline chloride, alginic acid sodium salt (sodium alginate), glucoheptonic acid sodium 5 salt, gluconic acid sodium salt (sodium gluconate), gluconic acid potassium salt (potassium gluconate), guanidine HCl, glucosamine HCI, amiloride HCl, monosodium glutamate (MSG), adenosine monophosphate salt, magnesium gluconate, potassium tartrate (monohydrate), and sodium tartrate (dihydrate). C. Combinations of Sweet Taste Improving Compositions 10 It has been discovered that combinations of at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving composition improve the temporal profile and/or flavor profile, including the osmotic taste, to be more sugar-like. One of ordinary skill in the art, with the teachings of the present invention, may arrive at all the possible combinations of natural and/or synthetic high-potency sweeteners and 15 sweet taste improving compositions. For example, non-limiting combinations of the natural and/or synthetic high-potency sweetener and sweet taste improving compositions include: 1. at least one natural-and/or synthetic high-potency sweetener and at least one carbohydrate; 20 2. at least one natural and/or synthetic high-potency sweetener and at least one polyol; 3. at least one natural and/or synthetic high-potency sweetener and at least one amino acid; 4. at least one natural and/or synthetic high-potency sweetener and at least 25 one other sweet taste improving additive; 5. at least one natural and/or synthetic high-potency sweetener, at least one carbohydrate, at least one polyol, at least one amino acid, and at least one other sweet taste improving additive; 6. at least one natural and/or synthetic high-potency sweetener, at least 30 one carbohydrate, and at least one polyol; WO 2007/061908 PCT/US2006/044798 27 7. at least one natural and/or synthetic high-potency sweetener, at least one carbohydrate, and at least one amino acid; 8. at least one natural and/or synthetic high-potency sweetener, at least one carbohydrate, and at least one other sweet taste improving additive; 5 9. - at least one natural and/or synthetic high-potency sweetener, at least one polyol, and at least one amino acid; 10. at least one natural and/or synthetic high-potency sweetener, at least one polyol, and at least one other sweet taste improving additive; 11. at least one natural and/or synthetic high-potency sweetener, at least 10 one amino acid, and at least one other sweet taste improving additive; 12. at least one natural and/or synthetic high-potency sweetener, at least one carbohydrate, at least one polyol, and at least one amino acid; 13. at least one natural and/or synthetic high-potency sweetener, at least one .carbohydrate, at least one polyol, and at least one other sweet taste 15 improving additive; 14. at least one natural and/or synthetic high-potency sweetener, at least one polyol, at least one amino acid, and at least one other sweet taste improving additive; and 15. at least one natural and/or synthetic high-potency sweetener, at least 20 one carbohydrate, at least one amino acid, and at least one other sweet taste improving additive. These fifteen major combinations further may be broken down into further combinations in order to improve the overall taste of the natural and/or synthetic high potency sweetener or the sweetened compositions comprising the natural and/or synthetic 25 high-potency sweetener. As explained above, the sweet taste improving composition is selected from the group consisting of polyols, carbohydrates, amino acids, other sweet taste improving additives, and combinations thereof. The other sweet taste improving additives useful in embodiments of this invention are described hereinabove. In one embodiment, a single 30 sweet taste improving composition may be used with a single natural or synthetic high potency sweetener and a cereal ingredient. In another embodiment of the present WO 2007/061908 PCT/US2006/044798 28 invention, a single sweet taste improving composition may be used. with one or more natural and/or synthetic high-potency sweeteners and a cereal ingredient. In yet another embodiment, one or more sweet taste improving compositions may be used with a single natural or synthetic high-potency sweetener and a cereal ingredient. In a further 5 embodiment, there may be a plurality of sweet taste improving compositions used in combination with one or more natural and/or synthetic high-potency sweeteners and a cereal ingredient. Thus, non-limiting examples of sweet taste improving composition combinations for embodiments of this invention include: i. at least one polyol, at least one carbohydrate, at least one amino acid, and at 10 least one other sweet taste improving additive; ii. at least one polyol, at least one carbohydrate, and at least one other sweet taste improving additive; iii. at least one polyol and at least one other sweet taste improving additive; iv. at least one polyol and at least one carbohydrate; 15 v. at least one carbohydrate and at least one other sweet taste improving additive; vi. at least one polyol and at least one amino acid; vii. at least one carbohydrate and at least one amino acid; viii. at least one amino acid and at least one other sweet taste improving 20 additive. Other sweet taste improving composition combinations in accordance with embodiments of this invention include: I. at least one polyol, at least one carbohydrate, and at least one amino acid; 25 2. at least one polyol, at least one carbohydrate, and at least one polyamino acid; 3. at least one polyol, at least one carbohydrate, and at least one sugar acid; 4. at least one polyol, at least one carbohydrate, and at least one nucleotide; 5. at least one polyol, at least one carbohydrate, and at least one organic acid; 6. at least one polyol, at least one carbohydrate, and at least one inorganic acid; 30 7. at least one polyol, at least one carbohydrate, and at least one bitter compound; WO 2007/061908 PCT/US2006/044798 29 8. at least one polyol, at least one carbohydrate, and at least one flavorant or flavoring ingredient; 9. at least one polyol, at least one carbohydrate, and at least one polymer; 10. at least one polyol, at least one carbohydrate, and at least one protein or protein 5 hydrolysate or protein or protein hydrolysate with low molecular weight amino acid; 11. at least one polyol, at least one carbohydrate, and at least one surfactant; 12. at least one polyol, at least one carbohydrate, and at least one flavonoid; 13. at least one polyol, at least one carbohydrate, and at least one alcohol; 10 14. at least one polyol, at least one carbohydrate, and at least one emulsifier; 15. at least one polyol, at least one carbohydrate, and at least one inorganic salt, 16. at least one polyol, at least one carbohydrate, and at least one organic salt, 17. at least one polyol, at least one carbohydrate, and at least one amino acid, and at least one other sweet taste improving additive; 15 18. at least one polyol, at least one carbohydrate, and at least one polyamino acid, and at least one other sweet taste improving additive; 19. at least one polyol, at least one carbohydrate, and at least one sugar acid, and at least one other sweet taste improving additive; 20. at least one polyol, at least one carbohydrate, and at least one nucleotide, and at 20 least one other sweet taste improving additive; 21. at least one polyol, at least one carbohydrate, and at least one organic acid, and at least one other sweet taste improving additive; 22. at least one polyol, at least one carbohydrate, and at least.'one inorganic acid, and at least one other sweet taste improving additive; 25 23. at least one polyol, at least one carbohydrate, and at least one bitter compound, and at least one other sweet taste improving additive; 24. at least one polyol, at least one carbohydrate, and at least one flavorant or flavoring ingredient, and at least one other sweet taste improving additive; 25. at least one polyol, at least one carbohydrate, and at least one polymer, and at 30 least one other sweet taste improving additive; WO 2007/061908 PCT/US2006/044798 30 26. at least one polyol, at least one carbohydrate, and at least one protein or protein hydrolysate, and at least one other sweet taste improving additive; 27. at least one polyol, at least one carbohydrate, and at least one surfactant, and at least one other sweet taste improving additive; . 5 28. at least one polyol, at least one carbohydrate, and at least one flavonoid, and at least one other sweet taste improving additive; 29. at least one polyol, at least one carbohydrate, and at least one alcohol, and at least one other sweet taste improving additive; 30. at least one polyol, at least one carbohydrate, at least one amino acid, and at 10 least one polyamino acid; 31. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, and at least one sugar acid; 32. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, and at least one nucleotide; 15 33. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, and at least one organic acid; 34. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one 20 organic acid, and at least one inorganic acid; 35. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide,. at least one organic acid, at least one inorganic acid, and at least one bitter compound; 36. at least one polyol, at least one carbohydrate, at least one amino acid, at'least 25 one polyamino acid, at least one sugar acid, at least. one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, and at least one polymer; 37. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino. acid, at least one sugar acid, at least one nucleotide, at least one 30 organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, and at least one protein or protein hydrolysate; WO 2007/061908 PCT/US2006/044798 31 38. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, and at least one 5 surfactant; 39. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, at least one surfactant, 10 and at least one flavonoid; 40. at least one polyol, at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, at least one surfactant, 15 at least one flavonoid, and at least one alcohol; 41. at least one polyol, at least one carbohydrate, at least one amino acid, and at least one sugar acid; 42. at least one polyol, at least one carbohydrate, at least one amino acid, and at least one nucleotide; 20 43. at least one polyol, at least one carbohydrate, at least one amino acid, and at least one organic acid; 44. at least one polyol, at least one carbohydrate, at least one amino acid, and at least one inorganic acid; 45. at least one polyol, at least one carbohydrate, at least one amino acid, and at 25 least one bitter compound; 46. at least one polyol, at least one carbohydrate, at least one amino acid, and at least one polymer; 47. at least one polyol, at least one carbohydrate, at least one amino acid, and at least one protein or protein hydrolysate; 30 48. at least one polyol, at least one carbohydrate, at least one amino acid, and at least one surfactant; WO 2007/061908 PCT/US2006/044798 32 49. at least one polyol, at least one carbohydrate, at least one .amino acid, and at least one flavonoid; 50. at least one polyol, at least one carbohydrate, at least one amino acid, and at least one alcohol; 5 51. at least one polyol, at least one carbohydrate, at least one polyamino acid, and at least one sugar acid; 52. at least one polyol, at least one carbohydrate, at least one polyamino acid, and at least one nucleotide; 53. at least one polyol, at least one carbohydrate, at least one polyamino acid, and 10 at least one organic acid; 54. at least one polyol, at least one carbohydrate, at least one polyamino acid, and at least one inorganic acid; 55. at least one polyol, at least one carbohydrate, at least one polyamino acid, and at least one bitter compound; 15 56. at least one polyol, at least one carbohydrate, at least one polyamino acid, and at least one polymer; 57. at least one polyol, at least one carbohydrate, at least one polyamino acid, and at least one protein or protein hydrolysate; 58. at least one polyol, at least one carbohydrate, at least one polyamino acid, and 20 at least one surfactant; 59. at least one polyol, at least one carbohydrate, at least one polyamino acid, and at least one flavonoid; 60. at least one polyol, at least one carbohydrate, at least one polyamino acid, and at least one alcohol; 25 61. at least one polyol,. at least one carbohydrate, at least one sugar acid, and at least one nucleotide; 62. at least one polyol, at least one carbohydrate, at least one sugar acid, and at least one organic acid; 63. at least one polyol, at least one carbohydrate, at least one sugar acid, and at 30 least one inorganic acid; WO 2007/061908 PCT/US2006/044798 33 64. at least one polyol, at least one carbohydrate, at least one sugar acid, and at least one bitter compound; 65. at least one polyol, at least one carbohydrate, at least one sugar acid, and at least one polymer, 5 66. at least one polyol, at least one carbohydrate, at'least one sugar acid, and at least one protein or protein hydrolysate; 67. at least one polyol, at least one carbohydrate, at least one sugar acid, and at least one surfactant; 68. at least one polyol, at least one carbohydrate, at least one sugar acid, and at 10 least one flavonoid; 69. at least one polyol, at least one carbohydrate, at least one sugar acid, and at least one alcohol; 70. at least one polyol, at least one carbohydrate, at least one nucleotide, and at least one organic acid; 15 71. at least one polyol, at least one carbohydrate, at least one nucleotide, and at least one inorganic acid; 72. at least one polyol, at least one carbohydrate, at least one nucleotide, and at least one bitter compound; 73. at least one polyol, at least one carbohydrate, at least one nucleotide, and at 20 least one polymer, 74. at least one polyol, at least one carbohydrate, at least one nucleotide, and at least one protein or protein hydrolysate; 75. at least one polyol, at least one carbohydrate, at least one nucleotide,' and at least one surfactant; 25 76. at least one polyol, at least one carbohydrate, at least one nucleotide, and at least one flavonoid; 77. at least one polyol, at least one carbohydrate, at least one nucleotide, and at least one alcohol; 78. at least one polyol, at least one carbohydrate, at least one organic acid, and at 30 least one inorganic acid; WO 2007/061908 PCT/US2006/044798 34 79. at least one polyol, at least one carbohydrate, at least one organic acid, and at least one bitter compound; 80. at least one polyol, at least one carbohydrate, at least one organic acid, and at least one polymer; 5 81. at least one polyol, at least one carbohydrate, at least one organic acid, and at least one protein or protein hydrolysate; 82. at least one polyol, at least one carbohydrate, at least one organic acid, and at least one surfactant; 83. at least one polyol, at least one carbohydrate, at least one organic acid, and at 10 least one flavonoid; 84. at least one polyol, at least one carbohydrate, at least one organic acid, and at least one alcohol; 85. at least one polyol, at least one carbohydrate, at least one inorganic acid, and at least one bitter compound; 15 86. at least one polyol, at least one carbohydrate, at least one inorganic acid, and at least one polymer; 87. at least one polyol, at least one carbohydrate, at least one inorganic acid, and at least one protein or protein hydrolysate; 88. at least one polyol, at least one carbohydrate, at least one inorganic acid, and at 20 least one surfactant; 89. at least one polyol, at least one carbohydrate, at least one inorganic acid, and at least one flavonoid; 90. at least one polyol, at least one carbohydrate, at least one inorganic acid, and at least one alcohol; 25 91.. at least one polyol, at least one carbohydrate, at least one bitter compound, and at least one polymer; *92. at least one polyol, at least one carbohydrate, at least one bitter compound, and at least one protein or protein hydrolysate; 93. at least one polyol, at least one carbohydrate, at least one bitter compound, and 30 at least one surfactant; WO 2007/061908 PCT/US2006/044798 35 94. at least one polyol, at least one carbohydrate, at least one bitter compound, and at least one flavonoid; 95. at least one polyol, at least one carbohydrate, at least one bitter compound, and at least one alcohol; 5 96. at least one polyol, at least one carbohydrate, at least one polymer, and at least one protein or protein hydrolysate; 97. at least one polyol, at least one carbohydrate, at least one polymer, and at least one surfactant; 98. at least one polyol, at least one carbohydrate, at least one polymer, and at least 10 one flavonoid; 99. at least one polyol, at least one carbohydrate, at least one polymer, and at least one alcohol; 100. at least one polyol, at least one carbohydrate, at least one protein or protein hydrolysate, and at least one surfactant; 15 101. at least one polyol, at least one carbohydrate, at least one protein or protein hydrolysate, and at least one flavonoid; 102. at least one polyol, at least one carbohydrate, at least one surfactant, and at least one flavonoid; 103. at least one polyol, at least one carbohydrate, at least one surfactant, and at 20 least one alcohol; and 104. at least one polyol, at least one carbohydrate, at least one flavonoid, and at least one alcohol. Other sweet taste -improving composition combinations in accordance with 25 embodiments of this invention include: 1. at least one polyol and at least one amino acid; 2. at least one polyol and at least one polyarnino acid; 3. at least one polyol and at least one sugar acid; 4. at least one polyol and at least one nucleotide; 30 5. at least one polyol and at least one organic acid; 6. at least one polyol and at least one inorganic acid; WO 2007/061908 PCTIUS2006/044798 36 7. at least one polyol and at least one bitter compound; 8. at least one polyol and at least one flavorant or flavoring ingredient; 9. at least one polyol and at least one polymer; 10. at least one polyol and at least one protein or protein hydrolysate; 5 11. at least one polyol and at least one surfactant; 12. at least one polyol and at least one flavonoid; 13. at least one polyol and at least one alcohol; 14. at least one polyol and at least one emulsifier; 15. at least one polyol and at least one inorganic salt; 10 16. at least one polyol and at least one organic salt; 17. at least one polyol and at least one protein or protein hydrolysate or mixture of low molecular weight amino acids; 18. at least one polyol, at least one amino acid, and at least one other sweet taste improving additive; 15 19. at least one polyol, at least one polyamino acid, and at least one other sweet taste improving additive: 20. at least one polyol, at least one sugar acid, and at least one other sweet taste improving additive; 21. at least one polyol, at least one nucleotide, and at least one other sweet taste 20 improving additive; 22. at least one polyol, at least one organic acid, and at least one other sweet taste improving additive; 23. at least one polyol, at least one inorganic acid, and at least one other sweet taste improving additive; 25 24. at least one polyol, at least one bitter compound, and at least one other sweet taste improving additive; 25. at least one polyol, at least one flavorant or flavoring ingredient, and at least one other sweet taste improving additive; 26. at least one polyol, at least one polymer, and at least one other sweet taste 30 improving additive; WO 2007/061908 PCT/US2006/044798 37 27. at least one polyol, at least one protein or protein hydrolysate, and at least one other sweet taste improving additive; 28. at least one polyol, at least one surfactant, and at least one other sweet taste improving additive; 5. 29. at least one polyol, at least one flavonoid, and at least one other sweet taste improving additive; 30. at least one polyol, at least one alcohol, and at least one other sweet taste improving additive; 31. at least one polyol, at least one amino acid, and at least one polyamino acid; 10 32. at least one polyol, at least one amino acid, at least one polyarnino acid, and at least one sugar acid; 33. at least one polyol, at least one amino acid, at least one polyamino acid, at least one sugar acid, and at least one nucleotide; 34. at least one polyol, at least one amino acid, at least one polyamino acid, at least 15 one sugar acid, at least one nucleotide, and at least one organic acid; 35. at least one polyol, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, and at least one inorganic acid; 36. at least one polyol, at least one amino acid, at least one polyamino acid, at least 20 one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, and at least one bitter compound; 37. at least one polyol, at least one amino acid, at least one polyanino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, and at least one polymer; 25 38. at least one polyol, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, and at least one protein or protein hydrolysate; 39. at least one polyol, at least one amino acid, at least one polyamino acid, at least 30 one sugar acid, at least one nucleotide, at least one organic acid, at least one WO 2007/061908 PCT/US2006/044798 38 inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, and at least one surfactant; 40. at least one polyol, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one 5 inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein' hydrolysate, at least one surfactant, and at least one flavonoid; 41. at least one polyol, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one 10 inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, at least one surfactant, at least one flavonoid, and at least one alcohol; 42. at least one polyol, at least one amino acid, and at least one sugar acid; 43. at least one polyol, at least one amino acid, and at least one nucleotide; 15 44. at least one polyol, at least one amino acid, and at least one organic acid; 45. at least one polyol, at least one amino acid, and at least one inorganic acid; 46. at least one polyol, at least one amino acid, and at least one bitter compound; 47. at least one polyol, at least one amino acid, and at least one polymer; 48. at least one polyol. at least one amino acid, and at least one protein or protein 20 hydrolysate; 49. at least one polyol, at least one amino acid, and at least one surfactant; 50. at least one polyol, at least one amino acid, and at least one flavonoid; 51. at least one polyol, at least one amino acid, and at least one alcohol; 52. at least one polyol, at least one polyamino acid, and at least one sugar acid; 25 53. at least one polyol, at least one polyamino acid, and at least one nucleotide; 54. at least one polyol, at least one polyamino acid, and at least one organic acid; 55. at least one polyol, at least one polyamino acid, and at least one organic salt; 56. at least one polyol, at least one polyamino acid, and at least one inorganic acid; 57. at least one polyol, at least one polyamino acid, and at least one inorganic salt; 30 58. at least one polyol, at least one polyamino acid, and at least one bitter compound; WO 2007/061908 PCT/US2006/044798 39 59. at least one polyol, at least one polyamino acid, and at least one polymer; 60. at least one polyol, at least one polyamino acid, and at least one protein or protein hydrolysate; 61. at least one polyol. at least one polyamino acid, and at least one surfactant; 5 62. at least one polyol, at least one polyamino acid, and at least one flavonoid; 63. at least one polyol, at least one polyamino acid, and at least one alcohol; 64. at least one polyol, at least one sugar acid, and at least one nucleotide; 65. at least one polyol, at least one sugar acid, and at least one organic acid; 66. at least one polyol, at least one sugar acid, and at least one inorganic acid; 10 67. at least one polyol, at least one sugar acid, and at least one bitter compound; 68. at least one polyol, at least one sugar acid, and at least one polymer; 69. at least one polyol, at least one sugar acid, and at least one protein or protein hydrolysate; 70. at least one polyol, at least one sugar acid, and at least one surfactant; 15 71. at least one polyol, at least one sugar acid, and at least one flavonoid; 72. at least one polyol, at least one sugar acid, and at least one alcohol; 73. at least one polyol, at least one nucleotide, and at least one organic acid; 74. at least one polyol, at least one nucleotide, and at least one inorganic acid; 75. at least one polyol, at least'one nucleotide, and at least one bitter compound; 20 76. at least one polyol, at least one nucleotide,.and at least one polymer; 77. at least one polyol, at least one nucleotide, and at least one protein or protein hydrolysate; 78. at least one polyol, at least one nucleotide,.and at least one surfactant; 79. at least one polyol, at least one nucleotide, and at least one flavonoid; 25 80. at least one polyol, at least one nucleotide, and at least one alcohol; 81. at least one polyol, at least one organic acid, and at least one inorganic acid; 82. at least one polyol, at least one organic acid, and at least one bitter compound; 83. at least one polyol. at least one organic acid, and at least one polymer; 84. at least one polyol, at least one organic acid, and at least one protein or protein 30 hydrolysate; 85. at least one polyol, at least one organic acid, and at least one surfactant; WO 2007/061908 PCT/US2006/044798 40 86. at least one polyol, at least one organic acid, and at least one flavonoid; 87. at least one polyol, at least one organic acid, and at least one alcohol; 88. at least one polyol, at least one inorganic acid, and at least one bitter compound; 5 89. at least one polyol, at least one inorganic acid, and at least one polymer; 90. at least one polyol, at least one inorganic acid, and at least one protein or protein hydrolysate; 91. at least one polyol, at least one inorganic acid, and at least one surfactant; 92. at least one polyol, at least one inorganic acid, and at least one flavonoid; 10 93. at least one polyol, at least one inorganic acid, and at least one alcohol; 94. at least one polyol, at least one bitter compound, and at least one polymer; 95. at least one polyol, at least one bitter compound, and at least one protein or protein hydrolysate; 96. at least one polyol, at least one bitter compound, and at least one surfactant; 15 97. at least one polyol, at least one bitter compound, and at least one flavonoid; 98. at least one polyol, at least one bitter compound, and at least one alcohol; 99. at least one polyol, at least one polymer, and at least one protein or protein hydrolysate; 100. at least one polyol, at least one polymer, and at least one surfactant; 20 101. at least one polyol, at least one polymer, and at least one flavonoid; 102. at least. one polyol, at least one polymer, and at least one alcohol; 103. at least one polyol, at least one protein or protein hydrolysate, and at least one surfactant; 104. at least one polyol, at least one protein or protein hydrolysate, and at least one 25 flavonoid; 105. at least one polyol, at least one surfactant, and at least one flavonoid; 106. at least one polyol, at least one surfactant, and at least one alcohol; 107. at least one polyol, at least one flavonoid, and at least one alcohol; 108. at least one sweet taste improving additive and erythritol; 30 109. at least one sweet taste improving additive and maltitol; 110. at least one sweet taste improving additive and mannitol; WO 2007/061908 PCT1US2006/044798 41 111. at least one sweet taste improving additive and sorbitol; 112. at least one sweet taste improving additive and lactitol; 113. at least one sweet taste improving additive and xylitol; 114. at least one sweet taste improving additive and isomalt; 5 115. at least one sweet taste improving additive and propylene glycol; 116. at least one sweet taste improving additive and glycerol; 117. at least one sweet taste improving additive and palatinose; 118. at least one sweet taste improving additive and reduced isomalto oligosaccharides; 10 119. at least one sweet taste improving additive and reduced xylo-oligosaccharides; 120. at least one sweet taste improving additive and reduced gentio oligosaccharides; 121. at least one sweet taste improving additive and reduced maltose syrup; 122. at least one sweet taste improving additive and reduced glucose syrup; 15 123. at least one sweet taste improving additive, erythritol, and at least one other polyol; 124. at least one sweet taste improving additive, maltitol, and at least one other polyol; 125. at least one sweet taste improving additive, mannitol, and at least one other 20 polyol; 126. at least one sweet taste improving additive, sorbitol, and at least one other polyol; 127. at least one sweet taste improving additive, lactitol, and at least one other polyol; 25 128. at least one sweet taste improving additive, xylitol, and at least one other polyol; 129. at least one sweet taste improving additive, isomalt, and at least one other polyol; 130. at least one sweet taste improving additive, propylene glycol, and at least one 30 other polyol; WO 2007/061908 PCT/US2006/044798 42 131. at least one sweet taste improving additive, glycerol, and at least one other polyol; 132. at least one sweet taste improving additive, palatinose, and at least one other polyol; 5. 133. at least one sweet taste improving additive, reduced isomalto-oligosaccharides, and at least one other polyol; 134. at least one sweet taste improving additive, reduced xylo-oligosaccharides, and at least one other polyol; 135. at least one sweet taste improving additive, reduced gentio-oligosaccharides, 10 . and at least one other polyol; 136. at least one sweet taste improving additive, reduced maltose syrup, and at least one other polyol; and 137. at least one sweet taste improving additive, reduced glucose syrup, and at least one other polyol. 15 Other sweet taste improving composition combinations in accordance with embodiments of this invention include: 1. at least one polyol and tagatose; 2. at least one polyol and trehalose; 20 . 3. at least one polyol and galactose; 4.. at least one polyol and rhamnose; 5. at least one polyol and dextrin; 6. at least one polyol and cyclodextrin; 7. at least one polyol and a-cyclodextrin, p-cyclodextrin, or y-cyclodextrin; 25 8. at least one polyol and maltodextrin; 9. at least one polyol and dextran; 10. at least one polyol and sucrose; 11. at least one polyol and glucose; 12. at least one polyol and fructose; 30 13. at least one polyol and threose; 14. at least one polyol and arabinose; WO 2007/061908 PCT/US2006/044798 43 15. at least one polyol and xylose; 16. at least one polyol and lyxose; 17. at least one polyol and allose; 18. at least one polyol and altrose; 5 19. at least one polyol and mannose; 20. at least one polyol and idose; 21. at least one polyol and talose; 22. at least one polyol and lactose; 23. at least one polyol and maltose; 10 24. at least one polyol and invert sugar; 25. at least one polyol and trehalose; 26. at least one polyol and isotrehalose; 27. at least one polyol and neotrehalose; 28. at least one polyol and palatinose; 15 29. at least one polyoi and galactose; 30. at least one polyol and beet oligosaccharides; 31. at least one polyol and'isomalto-oligosaccharides; 32. at least one polyol and isomaltose; 33. at least one polyol and isomaltotriose; 20 34. at least one polyol and panose; 35. at least one polyol and xylo-oligosaccharides; 36. at least one polyol and xylotriose; 37. at least one polyol and xylobiose; 38. at least one polyol and gentio-oligoscaccharides; 25 39. at least one polyol and gentiobiose; 40. at least one polyol and gentiotriose; 41. 'at least one polyol and gentiotetraose; 42. at least one polyol and sorbose; 43. at least one polyol and nigero-oligosaccharides; 30 44. at least one polyol and palatinose oligosaccharides; 45. at least one polyol and fucose; WO 2007/061908 PCT/US2006/044798 44 46. at least one polyol and fructooligosaccharides; 47. at least one polyol and kestose; 48. at least one polyol and nystose; 49. at least one polyol and maltotetraol; 5. 50. at least one polyol and maltotriol; 51. at least one polyol and malto-oligosaccharides; 52. at least one polyol and maltotriose; 53. at least one polyol and maltotetraose; 54. at least one polyol and maltopentaose; 10 55. at least one polyol and maltohexaose; 56. at least one polyol and maltoheptaose; 57. at least one polyol and lactulose; 58. at least one polyol and melibiose; 59. at least one polyol and raffinose; 15 60. at least one polyol and rhamnose; 61. at least one polyol and ribose; 62. at least one polyol and isomerized liquid sugars;, 63. at least one polyol and high fructose corn syrup (e.g. HFCS55, HFCS42, or HFCS90) or starch syrup; 20. 64. at least one polyol and coupling sugars; 65. at least one polyol and soybean oligosaccharides; 66. at least one polyol and glucose syrup; 67. at least one polyol, tagatose, and at least one other carbohydrate; 68. at least one polyol, trehalose, and at least one other carbohydrate; 25 69. at least one polyol, galactose, and at least one other carbohydrate; 70. at least one polyol, rhamnose, and at least one other carbohydrate; 71. at least one polyol, dextrin, and at least one other carbohydrate; 72. at least one polyol, cyclodextrin, and at least one other carbohydrate; 73. at least one polyol, $-cyclodextrin, and at least one other carbohydrate; 30 74. at least one polyol, maltodextrin, and at least one other carbohydrate; 75. at least one polyol, dextran, and at least one other carbohydrate; WO 2007/061908 PCT/US2006/044798 45 76. at least one polyol, sucrose, and at least one other carbohydrate; 77. at least one polyol, glucose, and at least one other carbohydrate; 78. at least one polyol, fructose, and at least one other carbohydrate; 79. at least one polyol, threose, and at least one other carbohydrate; 5 80. at least one polyol, arabinose, and at least one other carbohydrate; 81. at least one polyol, xylose, and at least one other carbohydrate; 82. at least one polyol, lyxose, and at least one other carbohydrate; 83. at least one 'polyol, allose, and at least one other carbohydrate;. 84. at least one polyol, altrose, and at least one other carbohydrate; 10 85. at least one polyol, mannose, and at least one other carbohydrate; 86. . at least one polyol, idose, and at least one other carbohydrate; 87. at least one polyol, talose, and at least one other carbohydrate; 88. at least one polyol, lactose, and at least one other carbohydrate; 89. at least one polyol, maltose, and at least one other carbohydrate; 15 90. at least one polyol, invert sugar, and at least one other carbohydrate; 91. at least one polyol, trehalose, and at least one other carbohydrate; 92. at least one polyol, isotrehalose, and at least one other carbohydrate; 93. at least one polyol, neotrehalose, and at least one other carbohydrate; 94. at least one polyol, palatinose, and at least one other carbohydrate; 20 95. at least one polyol, galactose, and at least one other carbohydrate; 96. at least one polyol, beet oligosaccharides, and at least one other carbohydrate; 97. at least one polyol, isomalto-oligosaccharides, and at least one other carbohydrate; 98. at least one polyol, isomaltose, and at least one other carbohydrate; 25 99. at least one polyol, isomaltotriose, and at least one other carbohydrate; 100. at least one polyol, panose, and at least one other carbohydrate; 101. at least one polyol, xylo-oligosaccharides, and at least one other carbohydrate; 102. at least one polyol, xylotriose, and at least one other carbohydrate; 103. at least one polyol, xylobiose, and at least one other carbohydrate; 30 104. at least one polyol, gentio-oligoscaccharides, and at least one other carbohydrate; WO 2007/061908 PCT/US2006/044798 46 105. at least one polyol, gentiobiose, and at least one other carbohydrate; 106. at least one polyol, gentiotriose, and at least one other carbohydrate; 107. at least one polyol, gentiotetraose, and at least one other carbohydrate; 108. at least one polyol, sorbose, and at least one other carbohydrate; 5 109. at least one polyol, nigero-oligosaccharides, and at least one other carbohydrate; 110. at least one polyol, palatinose oligosaccharides, and at least one other carbohydrate; 111. at least one polyol, fucose, and at least one other carbohydrate; 10 112. at least one polyol, fructooligosaccharides, and at least one other carbohydrate; '113. at least one polyol, kestose, and at least one other carbohydrate; 114. at least one polyol, nystose, and at least one other carbohydrate; 115. at least one polyol, maltotetraol, and at least one other carbohydrate; 116. at least one polyol, maltotriol, and at least one other carbohydrate; 15 117. at least one polyol, malto-oligosaccharides, and at least one other carbohydrate; 118. at least one polyol, maltotriose, and at least one other carbohydrate; 119. at least one polyol, maltotetraose, and at least one other carbohydrate; 120. at least one polyol, maltopentaose, and at least one other carbohydrate; 121. at least one polyol, maltohexaose, and at least one other carbohydrate; 20 122. at least one polyol, maltoheptaose, and at least one other carbohydrate; 123. at least one polyol, lactulose, and at least one other carbohydrate; 124. at least one polyol, melibiose, and at least one other carbohydrate; 125. at least one polyol, raffinose, and at least one other carbohydrate; 126. at least one polyol, rhamnose, and at least one other carbohydrate; 25 127. at least one polyol, ribose, and at least one other carbohydrate; 128. at least one polyol, isomerized liquid sugars, and at least one other carbohydrate; 129. at least one polyol, high fructose corn syrup (e.g. HFCS55, HFCS42, or HFCS90) or starch syrup, and at least one other carbohydrate; 30 130. at least one polyol. coupling sugars, and at least one other carbohydrate; WO 2007/061908 PCT/US2006/044798 47 131. at least one polyol, soybean oligosaccharides, and at least one other carbohydrate; 132. at least one polyol, glucose syrup, and at least one other carbohydrate; 133. at least one carbohydrate and erythritol; 5 134. at least one carbohydrate and maltitol; 135. at least one carbohydrate and mannitol; 136. at least one carbohydrate and sorbitol; 137. at least one carbohydrate and lactitol; 138. at least one carbohydrate and xylitol; 10 139. at least one carbohydrate and isomalt; 140. at least one carbohydrate and propylene glycol; 141. at least one carbohydrate and glycerol; 142. at least one carbohydrate and palatinose; 143. at least one carbohydrate and reduced isomalto-oligosaccharides; 15 144. at least one carbohydrate and reduced xylo-oligosaccharides; 145. at least one carbohydrate and reduced gentio-oligosaccharides; 146. at least one carbohydrate and reduced maltose syrup; 147. at least one carbohydrate and reduced glucose syrup; 148. at least one carbohydrate, erythritol, and at least one other polyol; 20 149. at least one carbohydrate, maltitol, and at least one other polyol; 150. at least one carbohydrate, mannitol, and at least one other polyol; 151. at least one carbohydrate, sorbitol, and at least one other polyol; 152. at least one carbohydrate, lactitol, and at least one other polyol; 153. at least one carbohydrate, xylitol, and at least one other. polyol; 25 154.. at least one carbohydrate, isomalt, and at least one other polyol; 155. at least one carbohydrate, propylene glycol, and at least one other polyol; 156. at least one carbohydrate, glycerol, and at least one other polyol; 157. at least one carbohydrate, palatinose, and at least one other polyol; 158. at least one carbohydrate, reduced isomalto-oligosaccharides, and at least one 30 other polyol; WO 2007/061908 PCT/US2006/044798 48 159. at least one carbohydrate, reduced xylo-oligosaccharides, and at least one other polyol; 160. at least one carbohydrate, reduced gentio-oligosaccharides, and at least one other polyol; 5 161. at least one carbohydrate, reduced maltose syrup, and at least one other polyol; and 162. at least one carbohydrate, reduced glucose syrup, and at least one other polyol. Other sweet taste improving composition combinations in accordance with 10 embodiments of this invention include: 1. at least one carbohydrate and at least one amino acid; 2. at least one carbohydrate and at least one polyamino acid; 3. at least one carbohydrate and at least one sugar acid; 4. at least one carbohydrate and at least one nucleotide; 15 5. at least one carbohydrate and at least one organic acid; 6. at least one carbohydrate and at least one inorganic acid; 7. at least one carbohydrate and at least one bitter compound; 8. at least one carbohydrate and at least one flavorant or flavoring ingredient; 9. at least one carbohydrate and at least one polymer; 20 10. at least one carbohydrate and at least one protein or protein hydrolysate; 11. at least one carbohydrate and at least one surfactant; 12. at least one carbohydrate and at least one flavonoid; 13. at least one carbohydrate and at least one alcohol; 14. at least one carbohydrate and at least one protein or protein hydrolysate or 25 mixture of low molecular weight amino acids; 15. at least one carbohydrate and at least one emulsifier, 16. at least one carbohydrate and at least one inorganic salt; 17. at least one carbohydrate, at least one amino acid, and at least one other sweet taste improving additive; 30 18. at least one carbohydrate, at least one polyamino acid, and at least one other sweet taste improving additive; WO 2007/061908 PCT/US2006/044798 49 19. at least one carbohydrate, at least one sugar acid, and at least one other sweet taste improving additive; 20. at least one carbohydrate, at least one nucleotide, and at least one other sweet taste improving additive; 5 21. at least one carbohydrate, at least one organic acid, and at least one other sweet taste improving additive; 22. at least one carbohydrate, at least one inorganic acid, and at least one other sweet taste improving additive; 23. at least one carbohydrate, at least one bitter compound, and at least one other 10 sweet taste improving additive; 24. at least one carbohydrate, at least one flavorant or flavoring ingredient, and at least one other sweet taste improving additive; 25. at least one carbohydrate, at least one polymer, and at least one other sweet taste improving additive; 15 26. at least one carbohydrate, at least one protein or protein hydrolysate, and at least one other sweet taste improving additive; 27. at least one carbohydrate, at least one surfactant, and at least one other sweet taste improving additive; 28. at least one carbohydrate, at least one flavonoid, and at least one other sweet 20 taste improving additive; 29. at least one carbohydrate, at least one alcohol, and at least one other sweet taste improving additive; 30. at least one carbohydrate, at least one amino acid, and at least one polyamino acid; 25 31. at least one carbohydrate, at least one amino acid, at least one polyamino acid, and at least one sugar acid; 32. at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, and at least one nucleotide; 33. at least one carbohydrate, at least one amino acid, at least one polyamino acid, 30 at least one sugar acid, at least one nucleotide, and at least one organic acid; WO 2007/061908 PCT/US2006/044798 50 34. at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, and at least one inorganic acid; 35. at least one carbohydrate, at least one amino acid, at least one polyarnino acid, 5 at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, and at least one bitter compound; 36. at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, and. at least one polymer; 10 37. at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, and at least one protein or protein hydrolysate; 38. at least one carbohydrate, at least one amino acid, at least one polyamino acid, 15 at least one sugar.acid, at least one nucleotide, at least one organic acid, at least one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, and at least one surfactant; 39. at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least 20 one inorganic acid, at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, at least one surfactant, and at least one flavonoid; 40. at least one carbohydrate, at least one amino acid, at least one polyamino acid, at least one sugar acid, at least one nucleotide, at least one organic acid, at least 25 one inorganic acid, -at least one bitter compound, at least one polymer, at least one protein or protein hydrolysate, at least one surfactant, at least one flavonoid, and at least one alcohol; 41. at least one carbohydrate, at least one amino acid, and at least one sugar acid; 42. at least one carbohydrate, at least one amino acid, and at least one nucleotide; 30 43. at least one carbohydrate, at least one amino acid, and at least one organic acid; WO 2007/061908 PCT[US2006/044798 51 44. at least one carbohydrate, at least one amino acid, and at least .one inorganic acid; 45. at least one carbohydrate, at least one amino acid, and at least one bitter compound; 5 46. at least one carbohydrate, at least one amino acid, and at least one polymer; 47. at least one carbohydrate, at least one amino acid, and at least one protein or protein hydrolysate; 48. at least one carbohydrate, at least one amino acid, and at least one surfactant; 49. at least one carbohydrate, at least one amino acid, and at least one flavonoid; 10 50. at least one carbohydrate, at least one amino acid, and at least one alcohol; 51. at least one carbohydrate, at least one polyamino acid, and at least one sugar acid; 52. at least one carbohydrate, at least one polyamino acid, and. at least one nucleotide; 15 53. at least one carbohydrate, at least one polyamino acid, and at least one organic acid; 54. at least one carbohydrate, at least one polyamino acid, and at least one inorganic acid; 55. at least one carbohydrate, at least one polyamino acid, and at least one bitter 20 compound; 56. at least one carbohydrate, at least one polyamino acid, and at least one polymer, 57. at least one carbohydrate, at least one polyamino acid, and at least one protein or protein hydrolysate; 25 58.. at least one carbohydrate, at least one polyamino acid, and at least one surfactant; 59. at least one carbohydrate, at least one polyamino acid, and at least one flavonoid; 60. at least one carbohydrate, at least one polyamino acid, and at least one alcohol; 30 61. at least one carbohydrate, at least one sugar acid, and at least one nucleotide; 62. at least one carbohydrate, at least one sugar acid, and at least one organic acid; WO 2007/061908 PCT/US2006/044798 52 63. at least one carbohydrate, at least one sugar acid, and at least one inorganic acid; 64. at least one carbohydrate, at least one sugar acid, and at least one bitter compound; 5 65. at least one carbohydrate, at least one sugar acid, and at least one polymer; 66. at least one carbohydrate, at least one sugar acid, and at least one protein or protein hydrolysate; 67. at least one carbohydrate, at least one sugar acid, and at least one surfactant; 68. at least one carbohydrate, at least one sugar acid, and at least one flavonoid; 10 69. at least one carbohydrate, at least one sugar acid, and at least one alcohol; 70. at least one carbohydrate, at. least one nucleotide, and at least one organic acid; 71. at least one carbohydrate, at least one nucleotide, and at least one inorganic acid; 72. at least one carbohydrate, at least one nucleotide, and at least one bitter 15 compound; 73. at least one carbohydrate, at least one nucleotide, and at least one polymer; 74. at least one carbohydrate, at least one nucleotide, and at least one protein or protein hydrolysate; 75. at least one carbohydrate, at least one nucleotide, and at least one surfactant; 20 76. at least one carbohydrate, at least one nucleotide, and at least one flavonoid; 77. at least one carbohydrate, at least one nucleotide, and at least one alcohol; 78.' at least one carbohydrate, at least one organic acid, and at least one inorganic acid; 79. at least one carbohydrate, at least one organic acid, and at least one bitter 25 compound; 80. at least one carbohydrate, at least one organic acid, and at least one polymer; 81. at least one carbohydrate, at least one organic acid, and at least one protein or protein hydrolysate; 82. at least one carbohydrate, at least one organic acid, and at least one surfactant; 30 83. at least one carbohydrate, at least one organic acid, and at least one flavonoid; 84. at least one carbohydrate, at least one organic acid, and at least one alcohol; WO 2007/061908 PCT/US2006/044798 53 85. at least one carbohydrate, at least one inorganic acid, and at least one bitter compound; 86. at least one carbohydrate, at least one inorganic acid, and at least one polymer, 87. at least one carbohydrate, at least one inorganic acid, and at least one protein or 5 protein hydrolysate; 88. at least one carbohydrate, at least. one inorganic acid, and at least one surfactant; 89. at .least one carbohydrate, at least one inorganic acid, and at least one flavonoid; 10 90. at least one carbohydrate, at least one inorganic acid, and at least one alcohol; 91. at least one carbohydrate, at least one -bitter compound, and at least one polymer, 92. at least one carbohydrate, at least one bitter compound, and at least one protein or protein hydrolysate; 15 93. at least one carbohydrate, at least one bitter compound, and.at least one surfactant; 94. at least one carbohydrate, at least one bitter compound, and at least one flavonoid; 95. at least one carbohydrate, .at least one bitter compound, and at least one 20 alcohol; 96. at least one carbohydrate, at least one polymer, and at least one protein or protein hydrolysate; 97. at least one carbohydrate, at least one polymer, and at least one surfactant; 98. at least one carbohydrate, at least one polymer, and at least one flavonoid; 25 99.. at least one carbohydrate, at least one polymer, and at least one alcohol; 100. at least one carbohydrate, at least one protein or protein hydrolysate, and .at -least one surfactant; 101. at least one carbohydrate, at least one protein or protein hydrolysate, and at least one flavonoid; 30 102.- at least one carbohydrate, at least one surfactant, and at least one flavonoid; 103. at least one carbohydrate, at least one surfactant, and at least one alcohol: WO 2007/061908 PCT/US2006/044798 54 104. at least one carbohydrate, at least one flavonoid, and at least one alcohol; 105. at least one sweet taste improving additive and D-tagatose; 106. at least one sweet taste improving additive and trelialose; 107. at least one sweet taste improving additive and D-galactose; 5 108. at least one sweet taste improving additive and rhainose; .109. at least one sweet taste improving additive and dextrin; 110. at least one sweet taste improving additive and cyclodextrin; 111. at least one sweet taste improving additive and 0-cyclodextrin; 112. at least one sweet taste improving additive and maltodextrin; 10 113. at least one sweet taste improving additive and dextran; 114. at least one sweet taste improving additive and sucrose; 115. at least one sweet taste improving additive and glucose; 116. at least one sweet taste improving additive and fructose; -117. at least one sweet taste improving additive and threose; 15 118. at least one sweet taste improving additive and arabinose; 119. at least one sweet taste improving additive and xylose; 120. at least one sweet taste improving additive and lyxose; 121. at least one sweet taste improving additive-and allose; 122. at least one sweet taste improving additive and altrose; 20. 123. at least one sweet taste improving additive and mannose; 124. at least one sweet taste improving additive and idose; 125. at least one sweet taste improving additive and talose; 126. at least one sweet taste improving additive and lactose; 127. at least one sweet taste improving.additive and maltose; 25 128. at least one sweet taste improving additive and invert sugar; 129. at least one sweet taste improving additive and trehalose; 130. at least one sweet taste improving additive and isotrehalose; 131. at least one sweet taste improving additive and neotrehalose; 132. at least one sweet taste improving additive and palatinose; 30 133. at least one sweet taste improving additive and galactose; 134. at least one sweet taste improving additive and beet oligosaccharides; WO 2007/061908 PCT/US2006/044798 55 135. at least one sweet taste improving additive and isomalto-oligosaccharides; 136. at least one sweet taste improving additive and isomaltose; 137. at least one sweet taste improving additive and isomaltotriose; 138. at least one.sweet taste improving additive and panose; 5 139. at least one sweet taste improving additive and xylo-oligosaccharides; 140. at least one sweet taste improving additive and xylotriose; 141. at least one sweet taste improving additive and xylobiose; 142. at least one sweet taste improving additive and gentio-oligoscaccharides; 143. at least one sweet taste improving additive and gentiobiose; 10 144. at least one sweet taste improving additive and gentiotriose; 145.- at least one sweet taste improving additive and gentiotetraose; 146. at least one sweet taste improving additive and sorbose; 147. at least one sweet taste improving additive and nigero-oligosaccharides; 148. at least one sweet taste improving additive and palatinose oligosaccharides; 15 149. at least one sweet taste improving additive and fucose; 150. at least one sweet taste improving additive and fructooligosaccharides; 151. at least one sweet taste improving additive and kestose; 152. at least one sweet taste improving additive and nystose; 153. at least one sweet taste improving additive and maltotetraol; 20 154. at least one sweet taste improving additive and maltotriol; 155. at least one sweet taste improving additive and malto-oligosaccharides; 156. at least one sweet taste improving additive and maltotriose; 157. at least one sweet taste improving additive and maltotetraose; 158. at least one sweet taste improving additive and maltopentaose; 25 159. at least one sweet taste improving additive and maltohexaose; 160. at least one sweet taste improving additive and maltoheptaose; 161. at least one sweet taste improving additive and lactulose; 162. at least one sweet taste improving additive and melibiose; 163. at least one sweet taste improving additive and raffinose; 30 164. at least one sweet taste improving additive and rhamnose; 165. at least one sweet taste improving additive and ribose; WO 2007/061908 PCT/US2006/044798 56 166. at least one sweet taste improving additive and isomerized liquid sugars; 167. at least one sweet taste improving additive and high fructose corn syrup (e.g., HFCS55, HFCS42, or HFCS90) or starch syrup; 168. at least one sweet taste improving additive and coupling sugars; 5 169. at least one sweet taste improving additive and soybean oligosaccharides; 170. at least one sweet taste improving additive and glucose syrup; 171. at least one sweet taste improving additive, D-tagatose, and at least one other carbohydrate; 172. at least one sweet taste improving additive, trehalose, and at least one other 10 carbohydrate; 173: at least one sweet taste improving additive, D-galactose, and at least one other carbohydrate; 174. at least one sweet taste improving additive, rhamnose, and at least one other carbohydrate; 15 175. at least one sweet taste improving additive, dextrin, and at least one other carbohydrate; 176. at least one sweet taste improving additive, cyclodextrin, and at least one other carbohydrate; 177. at least one sweet taste improving additive, s-cyclodextrin, and at least one 20 other carbohydrate; 178. at least one sweet taste improving additive, maltodextrin, and at least one other carbohydrate; 179. at least one sweet taste improving additive, dextran, and at least one other carbohydrate; 25 180.- at. least one sweet taste improving additive, sucrose, and at least one other carbohydrate; 181. at least one sweet taste improving additive, glucose, and at least one other carbohydrate; 182. at least one sweet taste improving additive, fructose, and at least one other 30 carbohydrate; WO 2007/061908 PCT/US2006/044798 57 183. at least one sweet taste improving additive, threose, and at least one other carbohydrate; 184. at least one sweet taste improving additive, arabinose, and at least one other carbohydrate; 5 185. at least one sweet taste improving additive, xylose, and at least one other carbohydrate; 186. 'at least one sweet taste improving additive, lyxose, and at least one other carbohydrate; 187. at least one sweet taste improving additive, allose, and at least one other 10 carbohydrate; 188. at least one sweet taste improving additive, altrose, and at least one other carbohydrate; 189. at least one sweet taste improving additive, mannose, and at least one other carbohydrate; 15 190. at least one sweet taste improving additive, idose, and at least one other carbohydrate; 191. at least one sweet taste improving additive, talose, and at least one other carbohydrate; 192. at least one sweet taste improving additive, Jactose, and at least one other 20 carbohydrate; 193. at least one sweet taste improving additive, maltose, and at least one other carbohydrate; 194. at least one sweet taste improving additive, invert sugar, and at least one other carbohydrate; 25 195. at least one sweet taste improving additive, trehalose, and at least one other carbohydrate; 196. .at least one sweet taste improving additive, isotrehalose, and at least one other carbohydrate; 197. at least one sweet taste improving additive, neotrehalose, and at least one other 30 carbohydrate; WO 2007/061908 PCT/US2006/044798 58 198. at least one sweet taste improving additive, palatinose, and at least one other carbohydrate; 199. at least one sweet taste improving additive, galactose, and.at least one other. carbohydrate; 5. 200. at least one sweet taste improving additive, beet oligosaccharides, and at least; one other carbohydrate; 201. at least one sweet taste improving additive. isomalto-oligosaccharides, and at least one other carbohydrate; 202. at least one sweet taste improving additive, isomaltose, and at least one other 10 carbohydrate; 203. at least one sweet taste improving additive, isomaltotriose, and at least one other carbohydrate; 204. at least one sweet taste improving additive, panose, and at least one other carbohydrate; 15 205. at least one sweet taste improving additive, xylo-oligosaccharides, and at least one other carbohydrate; 206. at least one sweet taste improving additive, xylotriose, and at least one other carbohydrate; 207. at least one sweet taste improving additive, ;ylobiose,.and at least one other 20 carbohydrate; 208. at least one sweet taste improving additive, gentio-oligoscaccharides, and at least one other carbohydrate; 209. at least one sweet taste improving additive, gentiobiose, and at least one other carbohydrate; 25 210. at least one sweet taste improving additive, gentiotriose, and at least one other carbohydrate; 211. at least one sweet taste improving additive, gentiotetraose, and at least one other carbohydrate; 212. at least one sweet taste improving additive, sorbose, and at least one other 30 carbohydrate; WO 2007/061908 PCTIUS2006/044798 59 213. at least one.sweet taste improving additive, nigero-oligosaccharides, and at least one other carbohydrate; 214. at least one sweet taste improving additive, palatinose oligosaccharides, and at least one other carbohydrate; 5 215. at least one. sweet taste improving additive, fucose, and at least one other carbohydrate; 216. at least one sweet taste improving additive, fructooligosaccharides, and at least one other carbohydrate; 217. at least one sweet taste improving additive, kestose, and at least one other 10 . carbohydrate; 218. at least one sweet taste improving additive, nystose, and at least one other carbohydrate; 219. at least one sweet taste improving additive, maltotetraol, and at least one other carbohydrate; 15 220. at least one sweet taste improving additive, maltotriol, and at least one other carbohydrate; 221. at least one sweet taste improving additive, malto-oligosaccharides, and at least one other carbohydrate; 222. at least one sweet taste improving additive, maltotriose, and at least one other 20 carbohydrate; 223. at least one sweet taste improving additive, maltotetraose, and at least one other carbohydrate; 224. at least one sweet taste improving additive, maltopentaose, and at least one other carbohydrate; 25 225. at least one sweet taste improving additive, maltohexaose, and at least one other carbohydrate; 226. at least one sweet taste improving additive, maltoheptaose, and at least one other carbohydrate; 227. at least one sweet taste improving additive, lactulose, and at least one other 30 carbohydrate; WO 2007/061908 PCTIUS2006/044798 60 228. at least one sweet taste improving additive, melibiose, and at least one other carbohydrate; 229. at least one sweet taste improving additive, raffinose, and at least one other carbohydrate; 5 230. at least one sweet taste improving additive, rhamnose, and at least one other carbohydrate; 231. at least one sweet taste improving additive, ribose, and at least one other carbohydrate 232. at least one sweet taste improving additive, isomerized liquid sugars, and at 10 least one other carbohydrate; 233. at least one sweet taste improving additive, high fructose corn syrup (e.g. HFCS55, HFCS42, or HFCS90) or starch syrup, and at least one other carbohydrate; 234. at least one sweet taste improving additive, coupling sugars, and at least one 15 other carbohydrate; 235. at least one sweet taste improving additive, soybean oligosaccharides, and at least one other carbohydrate; and 236. at least one sweet taste improving additive, glucose syrup, and at least one other carbohydrate. 20 In another embodiment, the cereal composition comprises at least one natural and/or 'synthetic high-potency sweetener and a cereal ingredient in combination with a plurality of sweet taste improving additives, desirably 3 or more sweet taste improving additives, and even more desirably 4 or more sweet taste improving additives, wherein each sweet taste improving additive is present in.an amount such that no one sweet taste 25 improving additive imparts a substantial off taste to the sweetener composition. In other words, the amounts of the sweet taste improving additives in the sweetener composition are balanced so that no one sweet taste improving additive imparts a substantial off taste to the sweetener composition. According to a particular embodiment of this invention, the sweetener composition 30 provided herein comprises at least one sweet taste improving composition in the sweetener composition in an amount effective for the sweetener composition to impart an osmolarity WO 2007/061908 PCT/US2006/044798 61 of at least 10 mOsmoles/L to an aqueous solution of the sweetener composition, wherein the at least one natural and/or synthetic high-potency sweetener is present in the aqueous solution in an amount sufficient to impart a maximum sweetness intensity equivalent to that of a 10% aqueous solution of sucrose by weight. As used herein, "mOsmoles/L" 5 refers to milliosmoles per liter. According to another embodiment, the sweetener composition comprises at least one sweet taste improving composition in an amount effective for the sweetener composition to impart an osmolarity of 10 to 500 mOsmoles/L, preferably 25 to 500 mOsmoles/L preferably, more preferably 100 to 500 mOsmoles/L, more preferably 200 to 500 mOsmoles/L, and still more preferably 300 to 500 10 mOsmoles/L to an aqueous solution of the sweetener composition, wherein the at least one natural and/or synthetic high-potency sweetener is present in the aqueous *solution in an amount sufficient to impart a maximum sweetness intensity equivalent to that of a 10% aqueous solution of sucrose by weight. Wherein a plurality of sweet taste improving compositions are combined with at least one natural and/or synthetic high-potency 15 sweetener, the osmolarity imparted is that of the total combination of the plurality of sweet taste improving compositions. Osmolarity refers to the measure oFf osmoles of solute per liter of solution, wherein osmole is equal to the number of moles of osmotically active particles in an ideal solution (e.g., a mole of glucose is one osmole), whereas a mole of sodium chloride is two 20 osmoles (one mole of sodium and one mole of chloride). Thus, in order to improve in the quality of taste of the sweetener composition, the osmotically active compounds or the compounds which impart osmolarity must not introduce significant off taste to the formulation. In one embodiment, suitable sweet taste improving carbohydrate additives for the 25 present invention have a molecular weight less than or equal to 500 and desirably have a molecular weight from 50 to 500. In particular embodiments, suitable carbohydrates with a molecular weight less than or equal to 500 include, but are not limited to, sucrose, fructose, glucose, maltose, lactose, mannose, galactose, and tagatose. Generally, in accordance with desirable embodiments of this invention, a sweet taste improving 30. carbohydrate additive is present in the sweetener compositions in an amount from about 1,000 to about 100,000 ppm. (Throughout this specification, the term ppm means parts WO 2007/061908 PCTIUS2006/044798 62 per million by weight or volume. For example, 500 ppm means 500 mg in a liter.) .In accordance with other desirable embodiments of this invention, a sweet taste improving carbohydrate additive is present in the sweetened compositions in an amount from about 2,500 to about 10,000 ppm. In another embodiment, suitable sweet taste .improving 5 carbohydrate additives for imparting osmolarities ranging from about 10. mOsmoles/L to about'500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving carbohydrate additives with a molecular weight ranging from about 50 to about 500. In one embodiment, suitable sweet taste improving polyol additives have a 10 molecular weight less than or equal to 500 and desirably-have a molecular weight from 76 to 500. In particular embodiments, suitable sweet taste improving polyol additives with a molecular weight less than or equal to 500 include, but are not limited to, erythritol, glycerol, and propylene glycol. Generally, in accordance with desirable embodiments of this invention, a sweet taste improving polyol additive is present in the sweetener 15 compositions in an amount from about 100 ppm to about 80,000 ppm. In accordance with other desirable embodiments of this invention, a sweet taste improving polyol additive is present in sweetened compositions in an amount from about 400 to about 80,000 ppm. In a sub-embodiment, suitable sweet taste improving polyol additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a 20 sweetenable composition include, but are not limited to, sweet taste improving polyol additives with a molecular weight ranging from about 76 to about 500. In accordance with still other desirable embodiments of this invention, a sweet taste improving polyol additive is present in sweetener compositions in an amount from about 400 to about 80,000 ppm of the total sweetener composition, more particularly from 25 about about 5,000 to about 40,000 ppm, and still more particularly from about 10,000 to about 35,000 ppm. Desirably, the at least one natural and/or synthetic high-potency sweetener and at least one sweet taste improving polyol additive are present in the sweetener composition in a ratio from about 1:4 to about 1:800, respectively; more particularly from about 1:20 to about 1:600; even more particularly from about 1:50 to 30 about 1:300; and still more.particularly from about 1:75 to about 1:150.
WO 2007/061908 PCT/US2006/044798 63 Generally, in accordance with another embodiment of this invention, a suitable sweet taste improving alcohol. additive is present in the sweetener compositions in an amount from about 625 to about 10,000 ppm. In another enibodiment, suitable sweet taste improving alcohol additives for imparting osmolarities ranging from about 10. 5 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving alcohol additives with a molecular weight ranging from about 46 to about 500. A non-limiting example of sweet taste improving alcohol additive . with a molecular weight ranging from about 46 to about 500 includes ethanol. In one embodiment, suitable. sweet taste improving amino acid additives have a 10 molecular weight of less than or equal to 250 and desirably have a molecular weight from 75 to 250. In particular embodiments, suitable sweet taste improving amino acid additives with a molecular weight less than or equal to 250 include, but are not limited to, glycine, alanine, serine, valine, leucine, isoleucine, proline, theanine, and threonine. Preferred sweet taste improving amino acid additives include those which are sweet tasting at high 15 concentrations, but desirably are present in embodiments of this invention at amounts below or above their sweetness taste detection threshold. Even more preferred are mixtures of sweet taste improving amino acid additives at amounts below or above their sweetness taste detection threshold. Generally, in accordance with-desirable embodiments of this invention, a sweet taste improving amino acid additive is present in the sweetener 20 compositions in an amount from about 100 ppm to about 25,000 ppm, more particularly from about 1,000 to about 10,000 ppm, and still more particularly from about 2,500 to about 5,000 ppm. In accordance with other desirable embodiments.of this invention, a sweet taste improving amino acid additive is present in the sweetened -compositions in an amount from about 250 ppm to about 7,500 ppm. In a sub-embodiment, suitable sweet 25 taste improving amino acid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving amino acid additives with a molecular weight ranging from about 75 to about 250. Generally, in accordance with yet another embodiment of this invention, a suitable 30 sweet taste improving amino acid salt additive is present in the sweetener compositions in an amount from about 25 to about 10,000 ppm, more particularly from about 1,000 to WO 2007/061908 PCT/US2006/044798 64 about 7,500 ppm, and still more particularly from about 2,500 to about 5,000 ppm. In another embodiment, suitable sweet taste improving amino acid salt additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving amino acid 5 salt additives with a-molecular weight ranging from about 75 to about 300. Non-limiting examples of sweet taste improving amino acid salt additives with a molecular weight ranging from about 75 to about 300 include salts of glycine, alanine, serine, theanine, and threonine. Generally, in accordance with still another embodiment of this invention, a suitable 10 sweet taste improving protein or protein hydroyslate additive is present in the sweetener compositions in an amount from about 200 to about 50,000 ppm. In another embodiment, suitable sweet taste improving protein or protein hydrolysate additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving protein or 15 protein hydrolysate additives with a molecular weight ranging from about 75 to about 300. Non-limiting examples of sweet taste improving protein or protein hydrolysate additives with a molecular weight ranging from about 75 to about 300 include proteins or protein hydrolysates containing glycine, alanine, serine, and threonine. Generally, in accordance with another embodiment of this invention, a suitable 20 sweet taste improving inorganic acid additive is present in the sweetener compositions in an amount from about 25 to about 5,000 ppm. In another embodiment, suitable sweet taste improving inorganic acid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, phosphoric acid, HCl, and H 2 S0 4 and any other inorganic acid additives which 25 are safe for human or animal consumption when used in a generally acceptable range. In a sub-embodiment, suitable sweet taste improving inorganic acid additives for .imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving inorganic acid additives with a molecular weight range from about 36 to about 98.
WO 2007/061908 PCT/US2006/044798 65 Generally, in accordance with still another embodiment of this invention, a suitable sweet taste improving inorganic acid salt additive is present in the sweetener compositions in an amount from about 25 to about 5,000 ppm. In another. embodiment, suitable sweet taste improving inorganic acid salt additives for imparting osmolarities ranging from about 5. 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, salts of inorganic acids, for example sodium, potassium, calcium, and magnesium salts of phosphoric acid, and any other alkali or alkaline earth metal salts* of other inorganic acids (e.g., sodium bisulfate) which are safe for human or animal consumption when used in a generally acceptable range. In a sub-embodiment, suitable 10 suitable sweet taste improving. inorganic acid salt additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, sweet taste improving inorganic acid salt additives with a molecular weight range from about 58 to about 120. Generally, in accordance with still another embodiment of this invention, a suitable 15 sweet taste improving organic acid additive is present in the sweetener compositions in an amount from about 10 to about 5,000 ppm. In another embodiment, suitable sweet taste improving organic acid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, creatine, citric acid, malic acid, succinic acid, hydroxycitric acid, tartaric acid, 20 fumaric acid, gluconic acid, glutaric acid, adipic acid, and any other sweet taste improving organic acid additives which are safe for human or animal consumption when used in a generally acceptable range. In one embodiment, the sweet taste improving organic acid additive comprises a molecular weight range from about 60 to about 208. Generally, in accordance with still another.embodiment of this invention, a suitable 25 sweet taste improving organic acid salt additive is present in the sweetener compositions in an amount from about 20 to about 10,000 ppm. In another embodiment, suitable sweet taste improving organic acid salt additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, salts of sweet taste improving organic acid additives, such as sodium, 30 potassium, calcium, magnesium, and other alkali or alkaline metal salts of citric acid, malic acid, tartaric acid, fumaric acid, gluconic acid, glutaric acid, adipic acid, WO 2007/061908 PCT/US2006/044798 66 hydroxycitric acid, succinic acid, and salts of any other sweet taste improving organic acid additives which are safe for human or animal consumption when used .in a generally acceptable range. In one embodiment, the sweet taste improving organic acid salt additive comprises a molecular weight range from about 140 to about 208. 5 Generally, in accordance with yet another embodiment of this invention, a suitable sweet taste improving organic base salt additive is present in the sweetener compositions in an amount from about 10 to about 5,000 ppm. In another embodiment, suitable sweet taste improving organic base salt additives for imparting 6smolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are 10 not limited'to, inorganic and organic acid salts of organic bases such as glucosamine salts, choline salts, and guanidine salts. Generally, in accordance with yet another embodiment of this invention, a suitable sweet taste improving astringent additive is present in the sweetener compositions in an amount from about 25 to about 1,000 ppm. In another embodiment, suitable sweet taste 15 improving astringent additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, tannic acid, tea polyphenols, catechins, aluminum sulfate; AINa(SO 4
)
2 ,
AIK(SO
4
)
2 and other forms of alum. Generally, in accordance with yet another embodiment of this invention, a suitable 20 sweet taste improving nucleotide additive is present in the sweetener- compositions in an amount from about 5 to about 1,000 ppm. In another embodiment, suitable sweet taste improving nucleotide additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, adenosine monophosphate. 25 Generally, in accordance with yet another embodiment of this invention, a suitable sweet taste improving polyamino acid additive is present in the sweetener compositions in an amount from about 30 to about 2,000 ppni. In another embodiment, suitable sweet taste improving polyamino acid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are WO 2007/061908 PCT/US2006/044798 67 not limited to, poly-L-lysine (e.g., poly-L-a-lysine or poly-L-e-lysine), poly-L-ornithine (e.g., poly-L-a-omithine or poly-L-E-omithine), and poly-L-arginine. Generally, in accordance with yet another embodiment of this invention, a suitable sweet taste improving polymer additive is present in the sweetener compositions in an 5. amount from about 30 to about 2,000 ppm. In another embodiment, suitable sweet taste improving polymer additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, chitosan, sodium hexametaphosphate and its salts, pectin, hydrocolloids such as gum acacia senegal, propylene glycol, polyethylene glycol, and poly(ethylene glycol 10 methyl ether). Generally, in accordance with yet another embodiment of this invention, a suitable sweet.taste improving surfactant additive is present in the sweetener compositions in an amount from about 1 to about 5,000 ppm. In another embodiment, suitable sweet taste improving surfactant additives for imparting osmolarities ranging from about 10 15 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but are not limited to, polysorbates, choline chloride, sodium taurocholate, lecithins, sucrose oleate esters, sucrose stearate esters, sucrose palmitate esters, and sucrlose laurate esters. Generally, in accordance with yet another embodiment of this invention, a suitable sweet taste improving flavonoid additive is present in the sweetener compositions in an 20 amount from about 0.1 to about 1,000 ppm. In another embodiment, suitable sweet taste improving flavonoid additives for imparting osmolarities ranging from about 10 mOsmoles/L to about 500 mOsmoles/L to a sweetenable composition include, but -are not limited to, naringin, catechins, rutins, neohesperidin, and neohesperidin dihydrochalcone. In a preferred embodiment, non-limiting examples of sweet taste improving 25 compositions enhancing the natural and/or synthetic high-potency sweetener's osmotic taste to be more sugar-like include sweet taste improving carbohydrate additives, sweet taste improving alcohol additives, sweet taste improving polyol additives, sweet taste improving amino acid additives, sweet taste improving amino acid salt additives, sweet taste improving inorganic acid salt additives, sweet-taste improving polymer additives, and 30 sweet taste improving protein or protein hydrolysate additives.
WO 2007/061908 PCT/US2006/044798 68 In another embodiment, suitable sweet taste improving carbohydrate additives for improving the osmotic taste of the natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving carbohydrate additives with a molecular weight ranging from about 50 to about 500. Non-limiting 5 examples of sweet taste improving carbohydrate additives with a molecular weight ranging from about 50 to about 500 include sucrose, fructose, glucose, maltose, lactose, mannose, galactose, ribose, rhamnose, trehalose, HFCS, and tagatose. In another embodiment, suitable sweet taste improving polyol additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be more 10 sugar-like include, but are not limited to, sweet taste improving poly6l additives with a molecular weight ranging from about 76 to about 500. Non-limiting examples of sweet taste improving polyol additives with a molecular weight ranging from about 76 to about 500 include erythritol, glycerol, and propylene glycol. In a sub-embodiment, other suitable sweet taste improving polyol additives include sugar alcohols. 15 In another embodiment, suitable sweet taste improving alcohol additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving alcohol additives with a molecular weight ranging from about 46 to about 500. A non-limiting example of sweet taste improving alcohol additive with a molecular weight ranging from about 46 to about 20 500 includes ethanol. In another embodiment, suitable sweet taste improving amino acid additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving amino acid additives with a molecular weight ranging from about 75 to about 250. Non-limiting examples of sweet 25 taste improving amino acid additives with a molecular weight ranging from about 75 to about 250 include glycine, alanine, serine, leucine, valine, isoleucine, proline, hydroxyproline, glutamine, theanine, and threonine. In another embodiment, suitable sweet taste improving amino acid salt additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be 30 more .sugar-like include, but are not limited to, sweet taste improving amino acid salt WO 2007/061908 PCT/US2006/044798 69 additives with a molecular weight ranging from about 75 to about 300. Non-limiting examples of sweet taste improving amino acid salt additives with a molecular weight ranging from about 75 to about 300 include salts of glycine, alanine, serine, leucine, valine, isoleucine, proline, hydroxyproline, glutamine, theanine, and threonine. 5 In another embodiment, suitable sweet taste improving protein or protein' hydrolysate additives for improving the osmotic taste of natural and/or synthetic high potency sweetener to be more sugar-like include, but are not limited to, sweet taste improving protein or protein hydrolysate additives with a molecular weight ranging from about 75 to about 300. Non-limiting examples of sweet taste improving protein or protein 10 hydrolysate additives with a molecular weight ranging from about 75 to about 300 include protein or protein hydrolysates containing glycine, alanine, seine, leucine, valine, isoleucine, proline, and threonine. In another embodiment, suitable sweet taste improving inorganic acid salt additives for improving the osmotic taste of natural and/or synthetic high-potency sweetener to be 15 more sugar-like include, but are not limited to, sodium chloride, potassium chloride, magnesium chloride, KH 2
PO
4 and NaH 2
PO
4 . Suitable sweet taste improving inorganic acid salt additives for improving the osmotic taste may comprise a molecular weight from about 58 to about 120. In another embodiment, suitable sweet taste improving bitter additives for 20 improving the osmotic taste of the natural and/or synthetic high-potency sweetener to be more sugar-like include, but are not limited to, caffeine, quinine, urea, quassia, tannic acid, and naringin. IV. Cereal Compositions In one embodiment, a cereal composition is provided comprising a cereal 25 ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving nucleotide additive chosen from inosine moriophosphate ("IMP"), guanosine monophosphate ("GMP"), adenosine monophosphate ("AMP"), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil 30 diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, WO 2007/061908 PCT/US2006/044798 70 cytosine triphosphate, uracil triphosphate, nucleosides thereof, nucleic acid bases thereof, or salts thereof. In one embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination 5 with at least one sweet taste improving carbohydrate additive chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., a-cyclodextrin, 0-cyclodextrin, and y cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, 10 palatinose .r isomaltulose, erythrose, deoxyribose, gulose, idose, talose, erythrulose, xylulose, psicose, turanose, cellobiose, amylopectin, glucosamine, mannosamine, fucose, glucuronic acid, gluconic acid, glucono-lactone, abequose, galactosamine, beet oligosaccharides, isomalto-oligosaccharides (isomaltose, isomaltotriose, panose and the like), xylo-oligosaccharides (xylotriose, xylobiose and the like), gentio-oligoscaccharides 15 (gentiobiose, gentiotriose, gentiotetraose and the like), sorbose, nigero-oligosaccharides, palatinose oligosaccharides, fucose, fructooligosaccharides (kestose, nystose and the like), maltotetraol, maltotriol, malto-oligosaccharides (maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose and the like), lactulose, melibiose, raffinose, rhamnose, ribose, isomerized liquid sugars such as high fructose corn/starch syrup (e.g., 20 HFCS55, HFCS42, HFCS90), coupling sugars, soybean oligosaccharides, or glucose syrup. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polyol additive chosen from erythritol, maltitol, 25 mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerine), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, or reduced glucose syrup. In another embodiment, a cereal composition is provided comprising a cereal 30 ingredient and at least one natural and/or synthetic high-potency sweetener in combination WO 2007/061908 PCTIUS2006/044798 71* with at least one sweet taste improving amino acid additive chosen from aspartic acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, valine, tyrosine, leucine, isoleucine, asparagine, serine, lysine, histidine, ornithine, methionine, carnitine, aminobutyric acid (alpha-, beta-, and gamma-isomers), glutamine, 5 hydroxyproline, taurine, norvaline, sarcosine, or salts thereof. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polyamino acid. additive chosen from .poly-L aspartic acid, poly-L-lysine (e.g., poly-L-a-lysine or poly-L-e-lysine), poly-L-ornithine 10 (e.g., poly-L-a-ornithine or poly-L-e-omithine), poly-L-arginine, other polymeric forms of amino acids, or salts thereof. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener, in combination with at least one sweet taste improving sugar acid additive chosen from aldonic, uronic, 15 aldaric, alginic, gluconic, glucuronic, glucaric, galactaric, galacturonic, or salts thereof. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one -sweet taste improving organic *acid additive chosen from C2-C30 carboxylic acids, substituted hydroxyl Cl-C30 carboxylic acids, benzoic acid, substituted 20 benzoic acids (e.g., 2,4-dihydroxybenzoic acid), substituted cinnamic acids, hydroxyacids, substituted hydroxybenzoic acids, substituted cyclohexyl carboxylic acids, tannic acid, lactic acid, tartaric acid, citric acid, gluconic acid, glucoheptonic acids, glutaric acid, creatine, adipic acid, hydroxycitric acid, malic acid, fruitaric acid, fumaric acid, maleic acid, succinic acid, chlorogenic acid, salicylic acid, caffeic acid, bile acids, acetic acid, 25 ascorbic acid, alginic acid, erythorbic acid, polyglutamic acid, or salts thereof. In another embodiment, a cereal composition is provided .comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving inorganic acid additive chosen from phosphoric acid, phosphorous acid, polyphosphoric acid, hydrochloric acid, sulfuric acid, carbonic 30 acid, sodium dihydrogen phosphate, or salts thereof.
WO 2007/061908 PCT/US2006/044798 72 In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination. with at least one sweet taste improving bitter compound additive chosen from caffeine, quinine, urea, bitter orange oil, naringin, quassia, or salts thereof. 5 In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving flavorant additive chosen from vanillin, vanilla extract, mango extract, cinnamon, citrus, coconut, ginger, viridiflorol, almond, menthol, grape skin extract, or grape seed extract. In another particular embodiment, the at least 10 one sweet taste improving flavorant additive comprises a proprietary sweetener chosen from DShlerTM Natural Flavoring Sweetness Enhancer K14323 (DShlerTM. Darmstadt, Germany), Syrnrise T M Natural Flavor Mask for Sweeteners 161453 or 164126 (SymriseTM, Holzminden, Germany), Natural AdvantageTM Bitterness Blockers 1, 2, 9 or 10 (Natural AdvantageTM, Freehold, New Jersey, U.S.A.), or SucramaskTM (Creative Research 15 Management, Stockton, California, U.S.A.) In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polymer additive chosen from chitosan, pectin, pectic, pectinic, polyuronic, polygalacturonic acid, starch, food hydrocolloid or crude 20- extracts thereof (e.g., gum acacia senegal, gum acacia seyal, carageenan), poly-L-lysine (e.g., poly-L-a-lysine or poly-L---lysine), poly-L-ornithine (e.g., poly-L-a-ornithine or poly-L-s-ornithine), polypropylene glycol, polyethylene glycol, poly(ethylene glycol methyl ether), polyarginine, polyaspartic acid, polyglutamic acid, polyethyleneimine, alginic acid, sodium alginate, propylene glycol alginate, sodium 25 polyethyleneglycolalginate, sodium hexametaphosphate and its salts, or other cationic and anionic polymers. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving protein hydrolysate additive chosen from bovine 30 serum albumin (BSA), whey protein (including fractions or concentrates thereof such as WO 2007/061908 PCT/US2006/044798 73 90% instant whey protein isolate, 34% whey protein, 50% hydrolyzed whey protein, and 80% whey protein concentrate), soluble rice protein, soy protein, protein isolates, protein hydrolysates, reaction products of protein hydrolysates, glycoproteins, and/or proteoglycans containing amino acids (e.g., glycine, alanine, serine, threonine, theanine, 5 asparagine, glutamine,. arginine, valine, isoleucine, leucine, norvaline, methionine, proline, tyrosine, hydroxyproline, or the like). In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving surfactant additive chosen from polysorbates (e.g., 10 polyoxyethylene sorbitan monooleate (polysorbate 80), polysorbate 20, polysorbate 60), sodium dodecylbenzenesulfonate, dioctyl sulfosuccinate or dioctyl sulfosuccinate sodium, sodium dodecyl sulfate, cetylpyridinium chloride, hexadecyltrimethylammonium bromide, sodium cholate, carbamoyl, choline chloride, sodium glycocholate, sodium taurocholate, sodium taurodeoxycholate, lauric arginate, sodium stearoyl lactylate, lecithins, sucrose 15 oleate esters, sucrose stearate esters, sucrose palmitate esters, sucrose laurate esters, and other emulsifiers, or the like. In another embodiment, a cereal composition is* provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving flavonoid additive chosen from catechins, 20 polyphenols, rutins, neohesperidin, naringin, neohesperidin dihydrochalcone, or the like. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with ethanol. In another embodiment, a cereal composition is provided comprising a cereal 25 ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving astringent compound additive chosen from tannic acid, europium chloride (EuCl 3 ), gadolinium chloride (GdClA), terbium chloride (TbC), alum, tannic acid, and polyphenols (e.g., tea polyphenol). In another embodiment, a cereal composition is provided comprising a cereal 30 ingredient and at least one natural and/or synthetic high-potency sweetener in combination WO 2007/061908 PCT/US2006/044798 74 with at least one sweet taste improving inorganic salt additive chosen from sodium chloride, potassium chloride, sodium dihydrogen phosphate, sodium sulfate, potassium. citrate, europium chloride (EuCl 3 ), gadolinium chloride (GdCl 3 ), terbium chloride (TbClA), magnesium sulfate, magnesium phosphate, alum, magnesium chloride, mono-, di-, tri 5 basic sodium or potassium salts of phosphoric acid, salts of hydrochloric acid, sodium carbonate, sodium bisulfate, or sodium bicarbonate. In another embodiment, a cereal composition is provided comprising a- cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving organic salt additive chosen from choline chloride, 10 gluconic acid sodium salt, gluconic acid potassium salt, guanidine HC1, amiloride HCl, glucosamine HCl, monosodium glutamate (MSG), adenosine monophosphate salt, magnesium gluconate, potassium tartrate, and sodium tartrate. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination 15 with at least one sweet taste improving nucleotide additive, at least one sweet taste improving carbohydrate additive, and at least one sweet* taste improving amino acid additive; wherein the at least one nucleotide additive is chosen 'from inosine monophosphate ("IMP"), guanosine monophosphate ("GMP"), adenosine monophosphate ("AMP"), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine 20' diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, nucleosides thereof, nucleic acid bases thereof, or salts thereof; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., a-cyclodextrin, p-cyclodextrin, and y 25 cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, erythrulose, xylulose, psicose, turanose, cellobiose, amylopectin; glucosamine, mannosamine, fucose, 30 glucuronic acid, gluconic acid, glucono-lactone, . abequose, galactosamine, beet oligosaccharides, isomalto-oligosaccharides (isomaltose, isomaltotriose, panose and the WO 2007/061908 PCT/US2006/044798 75 like), xylo-oligosaccharides (xylotriose, xylobiose and the like), gentio-oligoscaccharides (gentiobiose, gentiotriose, gentiotetraose and the like), sorbose, nigero-oligosaccharides, palatinose oligosaccharides, fucose, fructooligosaccharides (kestose, nystose and the like), maltotetraol, maltotriol, malto-oligosaccharides (maltotriose, maltotetraose, 5 maltopentaose, maltohexaose, maltoheptaose and the like), lactulose, melibiose, raffinose, rhamnose, ribose, isomerized liquid sugars such, as high fructose corn/starch syrup (e.g., HFCS55, HFCS42, HFCS90), coupling sugars, soybean oligosaccharides, or glucose syrup; and wherein the at least one amino acid additive is chosen from aspartic acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, 10 valine, tyrosine, leucine, isoleucine, asparagine, serine, lysine, histidine, ornithine, methionine, camitine, aminobutyric acid (alpha-, beta-, and gamma-isomers), glutamine, hydroxyproline, taurine, norvaline, sarcosine, or salts thereof. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination 15 with at least one sweet taste improving nucleotide additive and at least one sweet taste improving carbohydrate additive; wherein the at least one nucleotide additive is chosen from inosine monophosphate ("IMP"), guanosine monophosphate ("GMP"), adenosine monophosphate ("AMP"), cytosine monophosphate (CMP), . uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine 20 diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, nucleosides thereof, nucleic acid bases thereof, or salts thereof; and wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., Q-cyclodextrin, p cyclodextrin, and y-cyclodextrin), maltodextrin (including resistant maltodextrins such as 25 Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, erythrulose, xylulose, psicose, turanose, cellobiose, amylopectin, glucosamine, mannosamine, fucose, glucuronic acid, gluconic acid, glucono-lactone, abequose, 30 galactosamine, beet oligosaccharides, isomalto-oligosaccharides (isomaltose, isomaltotriose, panose and the like), xylo-oligosaccharides (xylotriose, xylobiose and the WO 2007/061908 PCT/US2006/044798 76 like), gentio-oligoscaccharides (gentiobiose, gentiotriose, genetiotetraose and the like), sorbose, nigero-oligosaccharides, palatinose oligosaccharides, fucose, fructooligosaccharides (kestose, nystose and the like), maltotetraol, maltotriol, malto oligosaccharides (maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose 5 and the like), lactulose, melibiose, raffinose, rhamnose, ribose, isomerized liquid sugars such as high fructose corn/starch syrup (e.g., HFCS55, HFCS42, HFCS90), coupling sugars, soybean oligosaccharides, or glucose syrup. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination 10 with at least one sweet taste improving nucleotide additive and at least one sweet taste improving polyol additive; wherein the at least one nucleotide additive is chosen from inosine monophosphate ("IMP"), guanosine monophosphate ("GMP"), adenosine monophosphate ("AMP"), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine 15 diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, cytosine triphosphate, uracil triphosphate, nucleosides'thereof, nucleic acid bases thereof, or salts thereof; and wherein the at least one polyol additive is chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isornalt, propylene glycol, glycerol (glycerine), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, 20 reduced xylo-oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, or reduced glucose syrup. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving nucleotide additive and at least one sweet taste 25 improving amino acid; wherein the at least one nucleotide additive is chosen from inosine monophosphate ("IMP"), guanosine monophosphate ("GMP"), adenosine monophosphate ("AMP"), cytosine monophosphate (CMP), uracil monophosphate (UMP), inosine diphosphate, guanosine diphosphate, adenosine diphosphate, cytosine diphosphate, uracil diphosphate, inosine triphosphate, guanosine triphosphate, adenosine triphosphate, 30 cytosine triphosphate, uracil triphosphate, nucleosides thereof, nucleic acid bases thereof, or salts thereof; and wherein the at least one amino acid additive is chosen from aspartic WO 2007/061908 PCT/US2006/044798 77 acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, valine, tyrosine, leucine, isoleucine, asparagine, shrine, lysine, histidine, ornithine, methionine, camitine, aminobutyric acid (alpha-, beta-, and gamma-isomers), glutamine, hydroxyproline, taurine, norvaline, sarcosine, or salts thereof. 5 In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive, at least one sweet taste improving polyol additive, and at least one sweet taste improving amino acid additive; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, 10 galactose, rhamnose, cyclodextrin (e.g., a-cyclodextrin, D-cyclodextrin, and y cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, erythrulose, 15 xylulose, psicose, turanose, cellobiose, amylopectin, glucosamine, mannosamine, fucose, glucuronic acid, gluconic acid, glucono-lactone, abequose,- galactosamine, beet oligosaccharides, isomalto-oligosaccharides (isomaltose, isomaltotriose, panose and the like), xylo-oligosaccharides (xylotriose, xylobiose and the like), gentio-oligoscaccharides (gentiobiose, gentiotriose, gentiotetraose and the like), sorbose, nigero-oligosaccharides, 20 palatinose oligosaccharides, fucose, fructooligosaccharides (kestose, nystose and the like), maltotetraol, maltotriol, malto-oligosaccharides (maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose and the like), lactulose, melibiose, raffinose, rhannose, ribose, isomerized liquid sugars such as high fructose corn/starch syrup (e.g., HFCS55, HFCS42, HFCS90), coupling sugars, soybean oligosaccharides, or glucose 25 syrup; wherein the at least one polyol additive is chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerine), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, or reduced glucose syrup; and wherein the at least one amino acid additive is chosen from aspartic 30 acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, valine, tyrosine, leucine, isoleucine, asparagine, serine, lysine, histidine, ornithine, WO 2007/061908 PCT/US2006/044798 78 methionine, carnitine, aminobutyric acid (alpha-, beta-, and gamma-isomers), glutamine, hydroxyproline, taurine, norvaline, sarcosine, or.salts thereof. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination 5 with at least one sweet taste improving carbohydrate additive and at least.one sweet taste improving polyol additive; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., a-cyclodextrin, p cyclodextrin, and y-cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, 10 lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, erythrulose, xylulose, psicose, turanose, cellobiose, amylopectin, glucosamine, mannosamine, fucose, glucuronic acid, gluconic acid, glucono-lactone, abequose, galactosamine, beet oligosaccharides, isomalto-oligosaccharides (isomaltose, 15 isomaltotriose, panose and the like), xylo-oligosaccharides (xylotriose, xylobiose and the like), gentio-oligoscaccharides (gentiobiose, gentiotriose, gentiotetraose and the like), sorbose, nigero-oligosaccharides, palatinose oligosaccharides, fucose, fructooligosaccharides (kestose, nystose and the like), maltotetraol, maltotriol, malto oligosaccharides (maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose 20 and the like), lactulose, melibiose, raffinose, rhamnose, ribose, isomerized liquid sugars such as high fructose corn/starch syrup (e.g., HFCS55, HFCS42, or -HFCS90), coupling sugars, soybean oligosaccharides, or glucose syrup; and wherein the at least one polyol additive is chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerine), threitol, galactitol, palatinose, reduced 25 isomalto-oligosaccharides, -reduced xylo-oligosaccharides, reduced gentio oligosaccharides, reduced maltose syrup, or reduced glucose syrup. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive and at least one sweet taste 30 improving amino acid additive; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., a-cyclodextrin, p- WO 2007/061908 PCT/US2006/044798 79 cyclodextrin, and y-cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, palatinose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, 5 erythrulose, xylulose, psicose, turanose, cellobiose, amylopectin, glucosamine, mannosamine, fucose, glucuronic acid, gluconic acid, glucono-lactone, abequose, galactosamine, beet oligosaccharides, isomalto-oligosaccharides (isomaltose, isomaltotriose, panose and the like), xylo-oligosaccharides (xylotriose, xylobiose and the like), gentio-oligoscaccharides (gentiobiose, gentiotriose, gentiotetraose and the like), 10 sorbose, nigero-oligosaccharides, palatinose oligosaccharides, fucose, fructooligosaccharides (kestose, nystose and the like), . maltotetraol, maltotriol, malto oligosaccharides (maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose and the like), lactulose, melibiose, raffinose, rhamnose, ribose, isomerized liquid sugars such as high fructose cornstarch syrup (e.g., HFCS55, HFCS42, or HFCS90), coupling 15 sugars, soybean oligosaccharides, or glucose syrup; and wherein the at least one amino acid additive is chosen from aspartic acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, valine, tyrosine, leucine, isoleucine, asparagine, serine, lysine, histidine, ornithine, methionine, carnitine, aninobutyric acid (alpha-, beta-, and gamma-isomers), glutamine, hydroxyproline, taurine, norvaline, 20 sarcosine, or salts-thereof. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polyol additive and at least one sweet taste improving amino acid additive; wherein the at least one polyol additive is chosen from 25 erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerin), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo-oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, or reduced glucose syrup; and wherein the at least one amino acid additive is chosen from aspartic acid, arginine, glycine, glutamic acid, proline, threonine, theanine, cysteine, 30 cystine, alanine, valine, tyrosine, leucine, isoleucine, asparagine, serine, lysine, histidine, WO 2007/061908 PCT/US2006/044798 80 ornithine, methionine, carnitine, aminobutyric acid (alpha-, beta-, and gamma-isomers), glutamine, hydroxyproline, taurine, norvaline, sarcosine, or salts thereof. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination 5 with at least one sweet taste improving polyol additive and at least one sweet taste improving inorganic salt additive; wherein the at least one polyol additive is chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, isomalt, propylene glycol, glycerol (glycerin), threitol, galactitol, palatinose, reduced isomalto-oligosaccharides, reduced xylo-oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, 10 or reduced .glucose syrup; and wherein the at least one inorganic salt *additive is chosen from sodium chloride, potassium chloride, sodium dihydrogen phosphate, sodium sulfate, potassium citrate, europium chloride (EuCI), gadolinium chloride (GdC 3 ), terbium chloride (TbCl 3 ), magnesium sulfate, alum, magnesium chloride, mono-,- di-, tri-basic sodium or potassium salts of phosphoric acid, salts of hydrochloric acid, sodium 15 carbonate, sodium bisulfate, or sodium bicarbonate. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive and at least one sweet taste improving inorganic salt additive; wherein the at least one carbohydrate additive is chosen 20 from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., a-cyclodextrin, p cyclodextrin, and y-cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose. neotrehalose, palatinose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, 25 erythrulose, xylulose, psicose, turanose, cellobiose, amylopectin, glucosamine, mannosamine, fucose, glucuronic acid, gluconic acid, glucono-lactone, abequose, galactosamine, beet oligosaccharides, isomalto-oligosaccharides -(isomaltose, isomaltotriose, panose and the like), xylo-oligosaccharides (xylotriose, xylobiose and the like), gentio-oligoscaccharides (gentiobiose, gentiotriose, gentiotetraose and the like), 30 sorbose, nigero-oligosaccharides, palatinose oligosaccharides, fucose, fructooligosaccharides (kestose, nystose and the like), maltotetraol, maltotriol, malto- WO 2007/061908 PCT/US2006/044798 81 oligosaccharides (maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose and the like), lactulose, melibiose, raffinose, rhamnose, ribose, isomerized liquid sugars such as high fructose corn/starch syrup (e.g., HFCS55, HFCS42, HFCS90), coupling sugars, soybean oligosaccharides, or glucose syrup; and wherein the at least one inorganic 5 salt additive is chosen from sodium chloride, potassium chloride, sodium dihydrogen phosphate, sodium sulfate, potassium citrate, europium chloride (EuClA), gadolinium chloride (GdClA), terbium chloride (TbClA), magnesium phosphate, magnesium sulfate, alum, magnesium chloride, mono-, di-, tri-basic sodium or potassium salts of phosphoric acid, salts of hydrochloric acid, sodium carbonate, sodium. bisulfate, or sodium 10 bicarbonate. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving carbohydrate additive, at least one sweet taste improving amino acid additive, and at least one sweet taste improving inorganic salt 15 additive; wherein the at least one carbohydrate additive is chosen from tagatose, trehalose, galactose, rhamnose, cyclodextrin (e.g., a-cyclodextrin, 0-cyclodextrin, and -y cyclodextrin), maltodextrin (including resistant maltodextrins such as Fibersol-2TM), dextran, sucrose, glucose, ribulose, fructose, threose, arabinose, xylose, lyxose, allose, altrose, mannose, idose, lactose, maltose, invert sugar, isotrehalose, neotrehalose, 20 palatinose or isomaltulose, erythrose, deoxyribose, gulose, idose, talose, erythilose, xylulose, psicose, .turanose, cellobiose, amylopectin, glucosamine, mannosamine, fucose, glucuronic acid, gluconic acid, glucono-lactone, abequose, galactosamine, beet oligosaccharides, isomalto-oligosaccharides (isomaltose, isomaltotriose, panose and the like), xylo-oligosaccharides (xylotriose, xylobiose and the like), gentio-oligoscaccharides 25 (gentiobiose, gentiotriose, gentiotetraose and the like), sorbose, nigero-oligosaccharides, palatinose oligosaccharides, fucose, fructooligosaccharides (kestose, nystose and the like), maltotetraol, maltotriol, malto-oligosaccharides (maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose and the like), lactulose, melibiose, raffinose, rhamnose, ribose, isomerized liquid sugars such as high fructose com/starch syrup (e.g., 30 HFCS55, HFCS42, HFCS90), coupling sugars, soybean oligosaccharides, or glucose syrup; wherein the at least one amino acid additive is chosen from aspartic acid, arginine, WO 2007/061908 PCT/US2006/044798 82 glycine, glutamic acid, proline, threonine, theanine, cysteine, cystine, alanine, valine, tyrosine, leucine, isoleucine, asparagine, serine, lysine, histidine, ornithine, methionine, carnitine, aminobutyric acid (alpha-, beta-, and gamma-isomers), glutamine, hydroxyproline, taurine, norvaline, sarcosine, or salts thereof; and wherein the at least one .5 inorganic salt additive is chosen from sodium chloride, potassium chloride, sodium sulfate, potassium citrate, europium chloride .(EuC 3 ), gadolinium chloride (GdClA), terbium chloride (TbCl 3 ), magnesium phosphate, magnesium sulfate, alum, magnesium chloride, mono-, di-, tri-basic sodium or potassium salts of phosphoric acid, salts of hydrochloric acid, sodium carbonate, sodium bisulfate, or sodium bicarbonate. 10 In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving polyol additive and at least one sweet taste improving polyamino acid additive; wherein the at least one polyol additive is chosen from erythritol, maltitol, mannitol, sorbitol, lactitol, xylitol, inositol, -isomalt, propylene 15 glycol, glycerol (glycerin), threitol, galactitol, palatinose, reduced isomalto oligosaccharides, reduced xylo-oligosaccharides, reduced gentio-oligosaccharides, reduced maltose syrup, or reduced glucose syrup; and wherein the at least one polyamino acid additive is chosen from poly-L-aspartic acid, poly-L-lysine (e.g.. poly-L-a-lysine or poly-L-c-lysine), poly-L-ornithine (e.g., poly-L-a-omithine or poly-L-e-omithine), poly 20 L-arginine, and other polymeric forms of amino acids, or salts thereof. In another embodiment, a cereal composition is provided comprising a cereal ingredient and at least one natural and/or synthetic high-potency sweetener in combination with at least one sweet taste improving protein or protein hydrolysate additive and at least one sweet taste improving inorganic salt additive; wherein the at least one sweet taste 25 improving protein or protein hydrolysate additive is chosen from bovine serum albumin (BSA), whey protein (including fractions or concentrates thereof such as 90% instant whey protein isolate, 34% whey protein, 50% hydrolyzed whey protein, and 80% whey protein concentrate), soluble rice protein, soy protein, protein isolates, protein hydrolysates, reaction products of protein hydrolysates, glycoproteins, and/or 30 proteoglycans containing amino acids (e.g., glycine, alanine, serine, threonine, theanine, asparagine, glutamine, arginine, valine, isoleucine, leucine, norvaline, methionine, proline, WO 2007/061908 PCT/US2006/044798 83 tyrosine, hydroxyproline, or the like), collagen (e.g., gelatin), partially hydrolyzed collagen (e.g., hydrolyzed fish collagen), and collagen hydrolysates (e.g., porcine collagen hydrolysate); and wherein the at least one sweet taste improving inorganic salt additive is chosen from sodium chloride, potassium chloride, sodium sulfate, potassium citrate, 5 europium chloride (EuClA), gadolinium chloride (GdCI 3 ), terbium chloride (TbClA), magnesium phosphate, magnesium sulfate, alum, magnesium chloride, mono-, di-, tri basic sodium or potassium salts of phosphoric acid, salts of hydrochloric acid, sodium carbonate, sodium bisulfate, or sodium bicarbonate. In another embodiment, a cereal composition is provided comprising a cereal 10 ingredient and rebaudioside A in combination with at least one natural and/or synthetic high-potency sweetener other than rebaudioside-A and at least one sweet taste improving composition. In another particular embodiment, a cereal composition is provided comprising a cereal ingredient and rebaudioside A in combination with at least one synthetic high 15 potency sweetener, wherein the at least one synthetic high-potency sweetener functions as a sweet taste improving composition. Non-limiting examples of suitable sweet taste improving synthetic sweetener additives include sucralose, potassium acesulfame, aspartame, alitame, saccharin, neohesperidin dihydrochalcone, cyclamate, neotarne, N-[N [3-(3-hydroxy-4-methoxyphenyl)propyl]-L-a-aspartyl]-L-phenylalanine 1-methyl ester, N 20. [N-[3-(3-hydroxy-4-methoxyphenyl)-3-methylbutyll-L-a-aspartyl]-L-phenylalanine 1 methyl ester, N-[N-[3-(3-methoxy-4-hydroxyphenyl)propyl]-L-a-aspartyl]-L phenylalanine 1-methyl ester, salts thereof, and the like. In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside 25 IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, cyclamate, saccharin, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste improving polyol additive is provided. In a particular embodiment, the at least one sweet taste improving amino acid additive is present in an amount from about 100 ppm to about 30 25,000 ppm of the composition, and the at least one sweet taste improving polyol additive WO 2007/061908 PCT/US2006/044798 84 is present in an amount from about 400 to about 80,000 ppm of the composition. In a still more particular embodiment, the at least one sweet taste improving amino acid additive is glycine or alanine, and the at least one sweet taste improving polyol additive is erythritol. In one embodiment, a cereal composition comprising a cereal ingredient and a 5 sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, LUo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste improving protein or protein hydrolysate additive is provided. In a particular embodiment, 10 the at least. one sweet taste improving amino acid additive is present in an amount from about 100 to about 15,000 ppm of the composition, and the at least one sweet taste improving protein or protein hydrolysate additive is present in an amount from. about 200 ppm to about 50,000 ppm of the composition. In a still more particular embodiment, the at least one sweet taste improving amino acid additive is glycine or lysine, and the at least 15 one sweet taste improving protein or protein hydrolysate additive is a protein, a hydrolysate, or a reaction product of a hydrolysate of a protein containing glycine, alanine, serine, leucine, valine, isoleucine, proline, or threonine. In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside 20 IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving protein or protein hydrolysate additive and at least one sweet taste improving polyol additive is provided. In a particular embodiment, the at least one sweet taste improving protein or protein hydrolysate additive is present in an 25 amount from about 200 ppm to about 50,000 ppm of the composition, and at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition. In a still more particular embodiment, the at least one sweet taste improving protein or protein hydrolysate additive is a protein, a hydrolys ate, or a reaction product of a hydrolysate of proteins containing glycine, alanine, serine, leucine, 30 valine, isoleucine, proline, or threonine, and the at least one sweet taste improving polyol additive is erythritol.
WO 2007/061908 PCT/US2006/044798 85 In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination 5 with at least one sweet taste improving carbohydrate additive is provided. In a particular embodiment, the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm of the composition. In a still more particular embodiment, the sweetener composition comprises REBA and glucose, sucrose, HFCS, or D-fructose in an amount from about 10,000 ppm to about 80,000 ppm of the 10 .composition. In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination 15 with at least one sweet taste improving polyol additive is provided. . In a particular embodiment, the at least one sweet taste improving polyol additive-is present in an amount from about 400 to about 80,000 ppm of the composition. In another particular embodiment, the at least one sweet taste improving polyol additive is present in an amount from about 5,000.to about 60,000 ppm of the composition. Non-limiting examples include 20 a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with propylene glycol, erythritol, or combinations thereof. In one embodiment, a cereal composition comprising a cereal ingredient and a 25 sweetener composition comprising rebaudioside-A (REBA) (with at least 50 % REBA in a steviol glycoside mixture) in combination with at least one sweet taste improving polyol additive is provided. Desirably, the at least one sweet taste improving polyol additive comprises erythritol. In a particular embodiment of the sweetener composition, rebaudioside A is present in an amount from about 100 to about 3,000 ppm and the 30 erythritol is present in an amount from about 400 to about 80,000 ppm of the total sweetener composition. In another embodiment of the sweetener composition, WO 2007/061908 PCT/US2006/044798 86 rebaudioside A is present in an amount from about 100 to about 3,000.ppm and the erythritol is present in an amount from about 5,000 to about 40,000 ppm of the total sweetener composition. In still another embodiment of the sweetener composition, rebaudioside A is present in an amount from about 100 to about 3,000 ppm and the 5 erythritol is present in an amount from about 10,000 to about 35,000 ppm of the total sweetener composition. In another particular embodiment of the sweetener composition, rebaudioside A and erythritol are present in the sweetener composition in a ratio from about 1:4 to .about 1:800, respectively. In yet another particular embodiment of the sweetener composition, rebaudioside A and erythritol are present in the sweetener 10 composition in a ratio from about 1:20 to about 1:600, respectively; more particularly from about 1:50 to about 1:300; and still more particularly from about 1:75 to about 1:150. In another embodiment, a cereal composition comprising a cereal ingredient and a. sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, or curculin, in combination with at 15 least one sweet taste improving synthetic sweetener additive is provided. In a particular embodiment, the cereal composition comprises a cereal. ingredient and a sweetener comprising rebaudioside-A (REBA) in combination with saccharin or acesulfame potassium or other salts in an amount from about 10 ppm to about 100 ppm of the composition. 20. In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving carbohydrate additive and at least one sweet taste 25 improving polyol additive is provided. In a particular embodiment, the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm of the composition and at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition. Non limiting examples include a cereal ingredient and a sweetener composition comprising 30 rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame WO 2007/061908 PCT/US2006/044798 87 potassium or other salts, or neotame, in combination with tagatose, fructose or sucrose and erythritol. In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside 5 IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose,. saccharin, cyclamate, aspartame, acesulfame potassium or -other salts, or neotame, in combination with at least one sweet taste improving inorganic salt additive is provided. Non-limiting examples include a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo 10 sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with NaCl, KCI, NaHS0 4 .H20, NaH 2
PO
4 , MgSO 4 , KAI(SO 4
)
2 (alum), magnesium phosphate, magnesium chloride, KCl and KH 2
PO
4 , or other combinations thereof. A particularly desirable embodiment comprises the a cereal ingredient and a sweetener composition comprising rebaudioside-A 15 (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with a mixture of inorganic salt additives, such as chlorides, phosphates, and sulfates of sodium, magnesium, potassium, and calcium (e.g., sodium chloride and potassium chloride; potassium phosphate and potassium chloride; 20 sodium chloride and sodium phosphate; calcium phosphate and calcium sulfate; magnesium chloride and magnesium phosphate; and calcium phosphate, calcium sulfate, and potassium sulfate). In a particular embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprises aspartame, acesfulame potassium or other salts, 25 and sucralose in combination with at least one sweet taste improving inorganic salt additive. In a particular embodiment, the at least one sweet taste improving inorganic salt additive is present in an amount in the range of about 25 to about 5,000 ppm of the composition. Non-limiting examples include a cereal ingredient and a sweetener composition comprising aspartame, acesulfame potassium, and sucralose in combination 30 with magnesium chloride; a cereal ingredient and a sweetener composition comprising aspartame, acesulfame potassium, and sucralose in combination with magnesium sulfate; WO 2007/061908 PCT/US2006/044798 88 or a cereal ingredient and a sweetener composition comprising aspartame, acesulfame potassium, and sucralose in combination with magnesium sulfate and sodium chloride. In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside 5 IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving organic acid salt additive is .provided. - Non limiting examples include a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo 10 sweetener, monatin, curculin, sucrdlose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with choline chloride in citrate buffer, D-gluconic acid sodium salt, guanidine HCl, D-glucosamine HCI, amiloride HCl, or combinations thereof. In one embodiment, a cereal composition comprising a cereal ingredient and a 15 sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving organic acid additive is provided. Non-limiting examples include a cereal ingredient and a sweetener composition comprising 20- rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V. Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with fumaric acid, malic acid, tartaric acid, citric acid, adipic acid, ascorbic acid, tannic acid, succinic acid, glutaric acid, or combinations thereof. 25. In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive is provided. In a particular 30 embodiment, the at least one sweet taste improving amino acid additive is present in an WO 2007/061908 PCT/US2006/044798 89 amount from about 100 to about 25,000 ppm of the composition. Non-limiting examples include a cereal ingredient and a sweetener. composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or 5 other salts, or neotame, in combination with glycine, L-alanine, L-serine, L-threonine, alanine, aminobutyric acid (alpha-, beta-, or gamma-isomers), L-aspartic acid, L-glutamic acid, L-lysine, glycine and L-alanine mixture, salt derivatives or combinations thereof. In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside 10 lV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving surfactant additive is provided. Non-limiting examples include a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo 15 sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfane potassium or other salts, or neotame, in combination with dioctyl sulfosuccinate sodium, cetylpyridinium chloride, hexadecyltrimethylammonium . bromide, sucrose oleate, polysorbate 20, polysorbate 80, lecithin, or combinations thereof. In one embodiment, a cereal composition comprising a cereal ingredient and a 20 sweetener composition comprising rebaudioside-A (IEBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or. other salts, or neotame, in combination with at least one sweet taste improving polymer additive is provided. Non-limiting examples include a cereal ingredient and a sweetener composition comprising 25 rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with cationic polymer such as polyethyleneimine, poly-L-lysine (e.g., poly-L-a-lysine or poly-L-s-lysine), poly-L ornithine (e.g., poly-L-a-omithine or poly-L-e-ornithine), chitosan, or combinations 30 thereof.
WO 2007/061908 PCT/US2006/044798 90 In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination 5 with at least one sweet taste improving polymer additive and at least one sweet taste improving polyol additive is provided. In a particular embodiment, the at least one sweet taste improving polymer additive is present in an amount from about 30 to about 2,000 ppm of the composition, and the at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition. Non 10 limiting examples include a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with a hydrocolloid, such as a gum acacia seyal, and erythritol. 15 In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving protein or protein hydrolysate additive is provided. 20 Non-limiting examples include a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate,* aspartame, acesulfame potassium or other salts, or neotame, in combination with bovine serum albumin (BSA), whey protein or combinations thereof. 25 In one embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV,' mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste 30 improving inorganic acid salt additive is provided. In a particular embodiment, the at least one sweet taste improving amino acid additive is present in an amount from about 100 to WO 2007/061908 PCT/US2006/044798 91 about 25,000 ppm of the composition and the at least one sweet taste improving inorganic acid salt additive is present in an amount from about 25 to about 5,000 ppm of the composition. Non-limiting examples include a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, 5 mogroside V, Luo'Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and alum; a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or 10 other salts, or neotame, in combination with glycine and potassium chloride; a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and sodium chloride; a cereal ingredient and a 15 sweetener composition comprising REBA in combination with glycine, potassium dihydrogen phosphate, and potassium chloride; and rebaudioside-A (REBA), stevia, stevioside, morgroside IV, morgroside V, Lo Han Guo, monatin, curculin, sucralose, saccharin, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine, sodium chloride, and potassium chloride. 20. In another embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving carbohydrate additive and at least one sweet taste 25 improving inorganic acid salt additive is provided. In a particular embodiment, the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm of the composition and the at least one sweet taste improving inorganic acid salt additive is present in an amount from about 25 ppm to about 5,000 ppm. Non-limiting examples include a cereal ingredient and a sweetener composition 30 comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, WO 2007/061908 PCT/US2006/044798 92 acesulfame potassium or other salts, or neotame, in combination with fructose, sucrose, or glucose and alum; a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame .5 potassium or other salts, or neotame, in combination with fructose, sucrose, or glucose and potassium chloride; .a cereal ingredient and. a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside TV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with fructose, sucrose, or glucose and 10 sodium chloride; a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with fructose, sucrose, or glucose, potassium phosphate, and potassium chloride; and a cereal ingredient and a sweetener 15 composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with fructose, sucrose, or glucose, sodium chloride, and potassium chloride. In another embodiment, a cereal composition comprising a cereal ingredient and a 20 sweetener composition comprising rebaudioside-A (REllA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving bitter additive and at least one sweet taste improving inorganic salt additive is provided. A non-limiting example include a cereal 25 ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with urea and sodium chloride. In another embodiment, a cereal composition comprising a cereal ingredient and a 30 sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, WO 2007/061908 PCT/US2006/044798 93 cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet'taste improving polyamino acid additive is provided. In a particular embodiment, the at least one sweet taste improving amino acid additive is present in an amount from about 100 to 5 about 25,000- ppm of the composition and the at least one sweet taste improving polyamino acid additive is present in an amount from about 30 to about 2,000 ppm of the. composition. ' Non-limiting examples include a cereal ingredient and a sweetener composition comprising rebaudioside-A '(REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin; sucralose, saccharin, cyclamate, 10 aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and poly-a-L-lysine; and a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside,. mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and poly-E-L-lysine. 15 In another embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V. Luo Han Guo sweetener, inonatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one -sweet taste improving amino acid additive and at least one sweet taste 20. improving organic acid additive is provided. In a particular embodiment, the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition and the at least one sweet taste improving organic acid additive is present in an amount from about 10 to about 5,000 ppm of -the composition. A non-limiting example includes a cereal . ingredient and a -sweetener composition 25 comprising rebaudioside-A (REBA), stevia, stevioside,. mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with glycine and sodium gluconate. In another embodiment, a cereal composition comprising a cereal ingredient and a 30 sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, WO 2007/061908 PCT/US2006/044798 94 cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive and at least one sweet taste improving carbohydrate additive is provided. In a particular embodiment, the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 5 25,000 ppm of the composition and the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm of the composition. A non-limiting example includes a cereal ingredient and. a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, 10 aspartame, acesulfame potassium or other salts, or neotame, in combination with L-alanine and fructose. In another embodiment, a cereal composition comprising a cereal ingredient and a . sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, 15 cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive, at least one sweet taste improving polyol additive, at least one sweet taste improving inorganic salt additive, and at least one sweet taste improving organic acid salt additive is provided. In a particular embodiment, the at least one sweet taste improving amino acid additive is present in an 20 amount from about 100 to about 25,000 ppm of the composition, the at least one sweet - taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition, the at least one sweet taste improving inorganic salt additive is present in an amount from about 50 to about 5,000 ppm of the composition, and the at least one sweet taste improving organic acid salt additive is present in an amount from 25 about 20 to about 10,000 ppm of the composition. A non-limiting example includes a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with erythritol, glycine, KCl, KH 2
PO
4 , and choline chloride. 30 In another embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside WO 2007/061908 PCT/US2006/044798 95 IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame; acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid additive, at least one sweet taste improving carbohydrate additive, and at least one sweet taste improving polyol additive is 5 provided. In a particular embodiment, the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition, the at least one sweet taste improving carbohydrate additive is present in an amount from about 1,000 to about 100,000 ppm.of the composition, and the at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of 10 the composition. A non-limiting example includes a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside,. mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with L alanine, fructose, and erythritol. 15 In another embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving amino acid. additive, at least one sweet taste 20. improving polyol additive, and at least one sweet taste improving inorganic acid salt additive is provided. In a particular embodiment, the at least one sweet taste improving amino acid additive is present in an amount from about 100 to about 25,000 ppm of the composition, the at least one sweet taste improving polyol additive is present in an amount from about 400 to about 80,000 ppm of the composition, and the at least one sweet taste 25 improving inorganic acid salt additive is present in an amount from about 25 to about 5,000 ppm of the composition.- A non-limiting example includes a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, sucralose, saccha-in, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination 30 with erythritol, glycine, KCl, and KH 2
PO
4
.
WO 2007/061908 PCT/US2006/044798 96 In another embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, glycyrrihizin such as mono ammonium glycyrrhizic acid salt hydrate, sucralose, saccharin, cyclamate, aspartame, 5 acesulfame potassium or other salts, or neotame, in combination with a sweet taste improving inorganic acid salt additive is provided. A non-limiting example includes a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V. Luo Han Guo sweetener, monatin, curculin, glycyrrihizin such as mono-ammonium glycyrrhizic acid salt hydrate, sucralose, saccharin, 10 cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with sodium chloride. In one embodiment, a cereal composition is provided comprising a cereal ingredient and a sweetener composition comprising rebaudioside-A (REBA), stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, monatin, curculin, 15 glycyrrihizin such as mono-ammonium glycyrrhizic acid salt hydrate, sucralose, saccharin, cyclamate, aspartame, acesulfame potassium or other salts, or neotame, in combination with at least one sweet taste improving polyol additive and at least one sweet taste improving organic acid additive. Desirably, the at least one sweet taste improving polyol additive is present in an amount from about 20,000 to about 50,000 ppm of the 20 composition and the at least one sweet taste improving organic acid additive is present in an amount from about 10 to about 5,000 ppm of the composition. Wherein more than one sweet taste improving organic acid additive is present in the composition, the plurality of sweet taste improving organic acid additives are present in an amount from about 500 to about 2,500 ppm of the composition, more particularly in an amount from about 500 to 25 about 1,500 ppm of the composition. In a particular embodiment, the composition described hereinabove further comprises at least one sweet taste improving inorganic acid additive, at least one sweet taste improving inorganic acid salt additive, at least one sweet taste improving organic acid salt additive, or combinations thereof. In another embodiment, a cereal composition comprising a cereal ingredient and a 30 sweetener composition comprising REBA in combination with at least one sweet taste improving polyol additive and at least one sweet taste improving organic acid additive is WO 2007/061908 PCT/US2006/044798 97 provided. Desirably, the REBA has a purity from about 50 to about 100% by weight of REBA, more desirably from about 80 to about 99.5% by weight REBA, most desirably from about 97 to about 99.5% by weight REBA in a steviolglycoside mixture. In a particular embodiment, the REBA is present in the composition in an amount from about 5 100 to about 3,000 ppm, more desirably in an amount from about 200 to about 2.000 ppm, and even more desirably in an amount from about 250 to about 750 ppm of the composition. Desirably, the at least one sweet taste improving polyol additive is present in an amount from about 20,000 to about 50,000 ppm of the composition and the at least one sweet taste improving organic acid additive is present in an amount from about 10 to 10 about 5,000 ppm of the composition. In a particularly desirable embodiment, the at least one sweet taste improving polyol additive is present in an amount from about 30,000 to about 40,000 ppm and the at least one sweet taste improving organic acid additive is present in an amount from about 500 to about 2,500 ppm of the composition. In a particular embodiment, a plurality of sweet taste improving organic acid additives are 15 present in the sweetener composition in an amount from about 500 to about 2,500 ppm of the composition, the plurality of organic acid additives comprising a mixture of lactic acid in an amount from about 40 to about 250 ppm, citric acid in an amount from about 150 to about 460 ppm, malic acid in an amount from about 150 to about 460 ppm, and tartaric acid in an amount from about 150 to about 460 ppm. A non-limiting example includes a 20 cereal ingredient and a sweetener -composition comprising REBA in combination with erythritol, lactic acid, citric acid, malic acid, tartaric acid, or combinations thereof. In a particular embodiment, the sweetener composition comprises 34.000 ppm of erythritol, 80 ppm of lactic acid, 310 ppm of citric acid, 310 ppm of malic acid, 310 ppm or tartaric acid, and 550 ppm of REBA. Desirably, the REBA has a purity from about 80 to about 99.5% 25 by weight of REBA, more desirably from about 97 to about 99.5% by weight REBA in a steviolglycoside mixture. The sweetener composition optionally also may include flavorants such as caramel, vanilla, or other such flavorants as described herein, or combinations thereof. In another embodiment, a cereal composition comprising a cereal ingredient and a 30 sweetener composition comprising REBA in combination with at least one sweet taste improving polyol additive and at least one sweet taste improving organic acid additive WO 2007/061908 PCT/US2006/044798 98 described hereinabove further comprises at least one sweet taste improving inorganic acid additive. Desirably, at least one sweet taste improving inorganic acid additive is present in an amount from about 25 to about 5,000 ppm of the composition. Non-limiting examples of sweet taste improving inorganic acid additives include phosphoric acid, benzoic acid, 5 sorbic acid, and combinations thereof. In yet another embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising REBA in combination with at least one sweet taste improving polyol additive and at least one sweet taste improving organic acid additive described hereinabove further comprises at least one sweet taste improving 10 inorganic acid salt additive and/or at least one sweet taste improving organic acid salt additive. Desirably, the at least one sweet taste improving inorganic acid salt additive is present in an amount from about 25 to about 5,000 ppm of the composition, more desirably in an amount from about 50 to about 250 ppm, most desirably in an amount of about 150 ppm. Desirably, the at least one sweet taste improving organic acid salt additive 15 is present in an amount from about 20 to about 10,000 ppm of the composition, more desirably in an amount from about 50 to about 350 ppm, most desirably in an amount of about 148 ppm. Non-limiting examples include a cereal ingredient and a sweetener composition comprising REBA in combination with erythritol, sodium chloride or magnesium chloride, and lactic acid, citric acid, malic acid, tartaric acid, or combinations 20 thereof; a cereal ingredient and. a sweetener composition comprising REBA in combination with erythritol, potassium citrate or sodium citrate, and lactic acid, citric acid, malic acid, tartaric acid, or combinations thereof; or a cereal ingredient and a sweetener composition comprising REBA in combination with erythritol, sodium chloride and sodium citrate, lactic acid, citric acid, malic acid, and tartaric acid, or combinations 25 thereof. In another embodiment, a cereal composition comprising a cereal ingredient and a sweetener composition comprising REBA in combination with at least one sweet taste improving polyol additive, at least one sweet taste improving inorganic acid additive, and at least one sweet taste improving organic acid additive described hereinabove further 30 comprises at least one sweet taste improving inorganic acid salt additive and/or at least one sweet taste improving organic acid salt additive. Desirably, the at least one sweet WO 2007/061908 PCT/US2006/044798 99 taste improving inorganic acid salt additive is present in an amount from about 25 to about 5,000 ppm of the composition, more desirably in an amount from about 50 to about 250 ppm, most desirably in an amount of about 150 ppm. Desirably, the at least one sweet taste improving organic acid salt additive is present in an amount from about 20 to about 5 10,000 ppm of the composition, more desirably in an amount from about 50 to about 350 ppm, most desirably in an amount of about 148 ppm. Non-limiting examples .include a cereal ingredient and a sweetener composition comprising REBA in combination with erythritol, phosphoric acid, sodium chloride or magnesium chloride, and lactic acid, citric acid, malic acid, tartaric acid, or combinations thereof; a cereal ingredient and a sweetener 10 'composition comprising REBA in combination with erythritol, phosphoric acid, potassium citrate or sodium citrate, and lactic acid, citric acid, malic acid, tartaric acid, or combinations thereof; or a cereal ingredient and a sweetener composition comprising REBA in combination with erythritol, phosphoric acid, sodium chloride and sodium citrate, lactic acid, citric acid, malic acid, and tartaric acid, or combinations thereof. 15 The desired weight ratio of the natural and/or synthetic high-potency sweetener to sweet taste improving composition(s) in the sweetener composition will depend on the particular natural and/or synthetic high-potency sweetener, and the sweetness and other characteristics desired in the final product. Natural and/or synthetic high-potency sweeteners vary greatly in their potency, ranging from about 30 times more potent than 20. sucrose to about 8,000 times more potentthan sucrose on a weight basis. In general, the weight ratio of the natural and/or synthetic high-potency sweetener to sweet taste improving composition may for example range from range between 10,000:1 and 1:10,000; a further non-limiting example may range from about 9,000:1 to about 1:9,000; yet another example may range from about 8,000:1 to about 1:8,000; a further example 25 may range from about 7,000:1 to about 1:7,000; another example may range from about 6,000:1 to about 1:6000; in yet another example may range from about 5,000:1 to about 1:5,000; in yet another example.may range from about 4,000:1 to about 1:4,000; in yet another example may range from about 3,000:1 to about 1:3,000; in yet another example may range from about 2,000:1 to about 1:2,000; in yet another example may range from 30 about 1,500:1 to about 1:1,500; in yet another example may range from about 1,000:1 to about 1:1,000; in yet another example may range from about 900:1 to about 1:900; in yet WO 2007/061908 PCT/US2006/044798 100 another example may range from about 800:1 to about 1:800; in yet another example may range from about 700:1 to about 1:700; in yet another example may range from about 600:1 to about 1:600; in yet another example may range from about 500:1 to about 1:500; in yet another example may range from about 400:1 to about 1:400; in yet another 5 example may range from about 300:1 to about 1:300; in yet another example may range from about 200:1 to about 1:200; in yet another example may range from about 150:1 to about 1:150; in yet another example may range from about 100:1 to about 1:100; in yet another example may range from about 90:1 to about 1:90; in yet another example may range from about 80:1 to about 1:80; in yet another example may range from about 70:1 to 10 about 1:70; in yet another example may range from about 60:1 to about 1:60; in yet another example may range from about 50:1 to about 1:50; in yet another example may range from about 40:1 to about 1:40; in yet another example may range from about 30:1 to about 1:30; in yet another example may range from about 20:1 to about 1:20; in yet another example may range from about 15:1 to about 1:15; in yet another example may 15 range from about 10:1 to about 1:10; in yet another example may range from about 9:1 to about 1:9; in yet another example may range from about 8:1 to about 1:8; in yet another example may range from about 7:1 to about 1:7; in yet another example may range from about 6:1 to about 1:6; in yet another example may range from about 5:1 to about 1:5; in yet another example may range from about 4:1 to about 1:4; in yet another example may 20 range from about 3:1 to about 1:3; in yet another example may range from about 2:1 to about 1:2; and in yet another example may be about 1:1; depending on the particular natural and/or synthetic high-potency sweetener selected. It is contemplated that the combination of at least one natural and/or synthetic high-potency sweetener to at least one sweet taste improving composition may be carried 25 out in any pH range that does not materially or adversely affect the taste of the sweetener composition. A non-limiting example of the pH range may be from about 2 to about 8. A further example includes a pH range from about 2 to about 5. One of ordinary skill in the art may combine at least one natural and/or synthetic high-potency sweetener, at least one sweet taste improving composition, and sweetenble 30 composition in any manner. For example, at least one natural and/or synthetic high potency sweetener may be added to the sweetenble composition before the at least one WO 2007/061908 PCT1US2006/044798 101 sweet taste improving composition. In another example, at least one natural and/or synthetic high-potency sweetener may be added to the sweetenble composition after the at least one sweet taste improving composition. In yet another example, at least one natural and/or synthetic high-potency sweetener may be added to the sweetenble composition 5 simultaneously with the .at least one sweet taste improving composition. In yet another embodiment, at least one natural and/or synthetic high-potency sweetener may be combined with the at least one sweet taste improving composition prior to being added to a sweetenble composition. For example, the at least one natural and/or synthetic high-potency sweetener may be in a pure, diluted, or concentrated form as a 10 liquid (e.g., solution), solid (e.g., powder, chunk, pellet, grain, block, crystalline, or the like), suspension, gas state, or combinations thereof may be contacted with the at least one sweet taste improving composition which may be in a pure, diluted, or concentrated form as a liquid (e.g., solution), solid (e.g., powder, chunk, pellet, grain, block, crystalline, or the like), suspension, gas state, or combinations thereof before both aie contacted with a 15 sweetenble composition. In yet another embodiment, when there are more than one natural and/or synthetic high-potency sweeteners or more than one sweet taste improving composition in the sweeteneable composition, each component of the sweetenable composition may be added simultaneously, in an alternating pattern, in a random pattern, or any other pattern. 20 Generally, the amount of natural and/or synthetic high-potency sweetener present in a sweetened composition varies widely depending on the desired sweetness. Those of ordinary skill in the art can readily discern the appropriate amount of sweetener to put in the sweetened composition. In a particular embodiment, the at least one natural and/or synthetic high-potency sweetener is present in the sweetened composition in an amount in 25 the range of about 1 to about 5,000 ppm of the sweetened composition and the at least one sweet taste improving composition is present in the sweetened composition in an amount in the range of about 0.1 to about 100,000 ppm of the sweetened composition. In accordance with particular embodiments, suitable amounts of natural high potency sweeteners for sweetened compositions comprise amounts in the range from about 30 100 ppm to about 3,000 ppm for rebaudioside A; from about 50 ppm to about 3,000 ppm WO 2007/061908 PCT/US2006/044798 102 for stevia; from about 50 ppm to about 3,000 ppm for stevioside; from about 50 ppm to about 3,000 ppm for mogroside IV; from about 50 ppm to about 3,000 ppm for mogroside V; from about 50 ppm to about 3,000 ppm for Luo Han Guo sweetener; from about 5 ppm to about 300 ppm for monatin, from about 5 ppm to about 200 ppm for thaumatin; and 5 from about 50 ppm to about 3,000 ppm for mono-ammonium glycyrrhizic acid salt hydrate. In accordance with particular embodiments, suitable amounts of synthetic high potency sweeteners for sweetened compositions comprise a range from about 1 ppm to about 60 ppm for alitame; from about 10 ppm to about 600 ppm for aspartame; from about 10 1 ppm to about 20 ppm for neotame; from about 10 ppm to about 500 ppm for acesulfame potassium; from about 50 ppm to about 5,000 ppm for cyclamate; from about 10 ppm to about 500 ppm for saccharin; from about 5 ppm to about 250 ppm for sucralose; from about 1 ppm to about 20 ppm for N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl]-L-a aspartyl]-L-phenylalanine 1-methyl ester; from about 1 ppm to about 20 ppm for N-[N-[3 15 (3-hydroxy-4-methoxyphenyl)-3-methylbutyl]-L-a-aspartyl]-L-phenylalanine 1-methyl ester; and from about 1 ppm to about 20 ppm for N-[N-[3-(3-methoxy-4 hydroxyphenyl)propyl]-L-a-aspartyl]-L-phenylalanine 1-methyl ester. V. Cereal Formulations and Methods Methods of making cereal compositions are well known to those of ordinary skill 20 in the art. Generally, according to a particular embodiment, a mixture of dry ingredients is prepared. The mixing of ingredients may be performed by hand or with a mixing apparatus, such as a hand-held or free-standing mixer. The mixture is then passed through an extruder, and the extruded product is then dried. After the cereal is dried, the resulting cereal composition optionally may be coated, frosted, or glazed. 25 VI. Examples The present invention is further illustrated by the following examples, which are not to be construed in any way as imposing limitations upon the scope thereof. On the contrary, it is to be clearly understood that resort may be had to various other embodiments, modifications, and equivalents thereof which, after reading the description 30 therein, may suggest themselves to those skilled in the art without departing from the spirit WO 2007/061908 PCT/US2006/044798 103 of the present invention and/or the scope of the appended claims.. Unless otherwise specified, %'s are by weight. Example Set A 5 The following non-limiting examples provide recipes for several exemplary embodiments of low calorie cereal compositions provided herein. Example Al: A cereal composition coated with rebaudioside A and erythritol is prepared according to the following procedure: 10 First, the coating is prepared by adding 8.5 g of maltodextrin, 3 g of rebaudioside A, and 4 g of erythritol to about 15 g of oil and blending the mixture with a bench-top homogenizer. Second, 472.5 g of toasted cereal base is pre-heated for 3-5 minutes at 94*C. Third, the pre-heated toasted cereal base is placed in a panning or coating reel. 15 Fourth, the coating prepared in the first step is sprayed onto the pre-heated toasted cereal base using a spray nozzle selected to provide a fine, uniform atomization. Example A2: A Rebaudioside A and erythritol based frosting for cereal compositions is prepared 20 according to the following procedure: First, 90 g of maltodextrin salt is combined with 23.4 g of rebaudioside A, 50 g of erythritol, and 0.21 g of salt. Second, 102.69 g of water is. heated to about 42*C and then added to the ingredients combined in the first step. 25 Third, the mixture prepared in the second step is stirred at moderate speed for 5 minutes.
WO 2007/061908 PCT/US2006/044798 104 Fourth, the stirring speed is reduced, 30.96 g of vegetable oil is added to the mixture, and the stirring speed is then increased to created a suspension. Fifth, the suspension created in the fourth step is sprayed onto a cereal base using 1 g of suspension for every 2 grams of cereal base. 5 Sixth, the product prepared in the fifth step is dried at 82*C for about 20 minutes or until a moisture content of less than 3.0% is obtained. Example A3: A cereal composition with rebaudioside A and erythritol in the cereal matrix is 10 prepared using the following procedure: First, 20 kg of a flour base mix is prepared by combining 7.6 kg of com flour, 6 kg of wheat flour, 4 kg of oat flour, 2 kg of sugar, and 0.4 kg of salt. Second, the flour base mix of step one is mixed with 8 g of rebaudioside A and 700 g of erythritol for 15 minutes in a mixer. 15 Third, the mixture prepared in the second step is passed through an extruder at 100"C. Fourth,.the extruded cereal prepared in the third step is dried in dryer for about 5 minutes and is cooled for about 2 minutes. 20 Example A4: A high fiber cereal composition with rebaudioside A and erythritol in the cereal matrix blend is prepared using the following procedure: First, 20 kg of a high fiber base mix is prepared by combining 14.6 kg of heavy wheat bran, 2 kg of oat bran, 1 kg of com bran, 1 kg of graham flour, 1.2 kg of sugar, and 25 1 kg of salt. Second, the high fiber base mix of step one is mixed with 4.8 g of rebaudioside A and 420 g of erythritol for 15 minutes in a mixer.
WO 2007/061908 PCT/US2006/044798 105 Third, the mixture prepared in the second step is passed through an extruder at 100*C. Fourth, the extruded cereal prepared in the third step is dried in a dryer for 5 minutes and is cooled for about 2 minutes. 5 The following. Examples B1-B3, C1-C3, D, and E1-E3 illustrate methods of making purified rebaudioside A in accordance with particular embodiments of this invention: Example Set B 10 Table 2: Summary of Examples B1-3 Crude Solvent Heating Drying Yield HPLC Rebaudioside A Ethanol Methanol Water T ('C) T ('C) (g) Purity (a) (95%)(mL) (99%)(mL) (mL) (wt/wt %) BI 400 1200 400 320 50 50 130 98.9 B2 100 320 120 50 30-40 60 72 98.3 B3 50 160 60 25 -30 60 27.3 98.2 Example B1: Crude rebaudioside- A (77.4% purity) mixture was obtained from a commercial source. The impurities (6.2% stevioside, 5.6% rebaudioside C, 0.6 % rebauiodioside F, 15 1.0 % other steviolglycosides, 3.0% rebaudioside D, 4.9% rebaudioside B, 0.3% steviolbioside) were identified and quantified using HPLC on dry basis, moisture content 4.7%. Crude rebaudioside A (400 g), ethanol (95%, 1200 mL), methanol (99%, 400 rL) and water (320 mL) were combined and heated to 50*C for 10 minutes. The clear solution 20 was cooled to 22*C for 16 hours. The white crystals were filtered and washed twice with ethanol (2 x 200 mL, 95%) and dried in a vacuum oven at 50"C for 16-24 hours under reduced pressure (20 mm). The final composition of substantially pure rebaudioside A (130 g) comprised 98.91% rebaudioside A, 0.06% stevioside, 0.03% rebaudioside C, 0.12% rebaudioside F, 25 0.13% other steviolglycosides, 0.1% rebaudioside D, 0.49% rebaudioside B and 0.03% steviolbioside, all by weight.
WO 2007/061908 PCT/US2006/044798 106 Example B2: Crude rebaudioside A (80.37 %) was obtained from a commercial source. The impurities (6.22% stevioside, 2.28% rebaudioside C, 0.35% Dulcoside, 0.78 % 5 rebaudioside F, 0.72 % other steviolglycosides, 3.33% rebaudioside B, 0.07% steviolbioside) were identified by HPLC on dry basis, moisture content 3.4%. Crude rebaudioside A (100 g), ethanol (95%, 320 mL), methanol (99%, 120 mL) and water (50 mL) were combined and heated to 30-40 0 C for 10 minutes. The clear solution was cooled to 22cC for 16 hours. The white crystals were filtered and washed 10 twice with ethanol (2 x 50 mL, 95%). The wet filter cake (88 g) was slurried in ethanol (95%, 1320 mL) for 16 hours, filtered, washed with ethanol (95%, 2 x 100 mL) and dried in a vacuum oven at 60*C for 16-24 hours under reduced pressure (20 mm). The final composition of substantially pure rebaudioside A (72 g) comprised 98.29% rebaudioside A, 0.03% stevioside, 0.02% rebaudioside C, 0.17% rebaudioside F, 15 0.06% rebaudioside D and 1.09% rebaudioside B. Steviolbioside was not detected by HIPLC. Example B3:. Crude rebaudioside A (80.37%) was obtained from a commercial source. The impurities (6.22% stevioside, 2.28% rebaudioside C, 0.35% Dulcoside, . 0.78 % 20 rebaudioside F, 0.72 % other steviolglycosides, 3.33% rebaudioside B, 0.07% steviolbioside) were identified by HPLC on dry basis, moisture content 3.4%. Crude rebaudioside A (50 g), ethanol (95%, 160 mL), methanol (99%, 60 mL) and water (25 mL) were combined and heated to approximately 30*C for 10 minutes. The clear solution was cooled to 22*C for 16 hours. The white crystals were filtered and 25 washed twice with ethanol (2 x 25 mL, 95% ). The wet filter cake (40 g) was slurried in methanol (99%, 600 m.L) for 16 hours, filtered, washed with methanol (99%, 2 x 25 mL) and dried in a vacuum oven at 60*C for 16-24 hours under reduced pressure (20 mm). The final composition of substantially pure rebaudioside A (27.3g) comprised 98.22% rebaudioside A. 0.04% stevioside, 0.04% rebaudioside C, 0.18% rebaudioside F, WO 2007/061908 PCTfUS2006/044798 107 0.08% rebaudioside D and 1.03% rebaudioside B. Steviolbioside was not detected by HPLC. 5 Example Set C Table 3: Summary of Examples C1-3 Solvent Crude Ethanol Organic Water- Wash Solvent Yield HPLC Rebaudioside (95%)(MI) Co-solvent (ML) (g) Purity A (g) L) I (%) Cl 5 15 Methanol (6) 3.5 EtOH/MeOH 2.6 >99 (3:1 v/v) C2 5 15 Methanol (5) 4 EtOHIMeOH 2.3 >99. (3:1 v/v) C3 5 16 Methanol (6) 2.5 'EtOH/MeOH 3.2 >98 (8:3 v/v) _9_ Example C1: 10 A mixture of crude rebaudioside A (80.37 % purity, 5 g), ethanol (95%, 15 mL), methanol (5 mL) and water (3.5 mL) were combined and heated to reflux for 10 minutes. The clear solution was cooled to 22*C for 16 hours while stirring. The white crystalline product was filtered, washed twice with ethanol:methanol (5.0 mL, 3:1, v/v) mixture and dried in a vacuum oven at 50 0 C for 16-24 hours under reduced pressure (20 mm) to yield 15 2.6 g of purified product (>99% by HPLC). Example C2: A mixture of crude rebaudioside A (80.37 % purity, 5 g), ethanol (95%, 15 mL), methanol (5 mL) and water (4.0 mL) were combined and heated to reflux for 10 minutes. 20 The clear solution. was cooled to 22*C for 16 hours while stirring. The white crystalline product was filtered, washed twice with ethanol:methanol (5.0 mL, 3:1, v/v) mixture and dried in a vacuum oven at 504C for 16-24 hours under reduced pressure (20 mm) to yield 2.3 g of purified product (>99% by HPLC).
WO 2007/061908 PCT/US2006/044798 108 Example C3: A mixture of crude rebaudioside A (80.37 % purity, 5 g), ethanol (95%, 16 mL), methanol (6 mL) and water (2.5 mL) were combined and heated to reflux for 10 minutes. The clear solution was cooled to 22*C for 2 hours. During this time, crystals started to 5 appear. The mixture is stirred at room temperature for 16 hours. The white crystalline product was filtered, washed twice with ethanol:methanol (5.0 mL, 8:3, v/v) mixture and dried in a vacuum oven at 50*C for 16-24 hours under reduced pressure (20 mm) to yield 3.2 g of purified product (>98% by HPLC). 10 Example D Table 4: Summary of Example D Solvent Crude Organic Solvent Water Wash Solvent Yield HPLC Rebaudioside (ML) (mL) (g) Purity A (g) (%) D 50 EtOH (160) 40 EtOH 19.8 99.5 A mixture of crude rebaudioside A (80.37 % purity, 50 g), ethanol (95%, 160 mL) and water (40 mL) were combined and heated to reflux for 30 minutes. The mixture was 15 then allowed to cool to ambient temperature for 16-24 hours. The white crystalline product was filtered, washed twice with ethanol (95%, 25 mL), and dried in a vacuum oven at 60'C for 16-24 hours under reduced pressure (20 mm) to yield 19.8 g of purified product (99.5% by HPLC).
WO 2007/061908 PCT/US2006/044798 109 Example E Table 5: Summary of Examples E1-3 Crude Ethanol Organic Water Methanol Yield HPLC Rebaudloside '(95%)(mL) Co-solvent (mL) Slurry (g) Purity A (g) (mL) (mL) (%) El 50 160 Methanol 25 200 12.7 ' >97 (60) E2 50 160 Methanol 25 30D 18.6 >97 1 (60) E3 50 160 Methanol 25 350 22.2 >97 (60) 5 Example El: A mixture of crude rebaudioside A (41% purity, 50 g), ethanol (95%, 160 mL), methanol (99.8 %, 60 mL) and water (25 mL) were combined by stirring at.22*C. A white product crystallized out in 5-20 hours. The mixture was stirred for additional 48 hours. The white crystalline product was filtered and washed twice with ethanol (95%, 25 mL). 10 The wet cake of white crystalline product then was slurried in methanol (99.8 %, 200 mL) for 16 hours, filtered, washed twice with methanol (99.8 %, 25 mL), and dried in a vacuum oven at 60*C for 16-24 hours under reduced pressure (20 mm) to give 12.7 g of purified product (>97% by HPLC). 15 Example E2: A mixture of crude rebaudioside A (48% purity, 50 g), ethanol (95%, 160 mL), methanol (99.8 %, 60 mL) and water (25 mL) was combined by stirring at 22*C. The white product crystallized out in 3-6 hours. The mixture was stirred for additional 48 hours. The white crystalline product was filtered and washed twice with ethanol (95%, 25 20 mL). The wet cake of white crystalline product then was slurried in methanol (99.8 %, 300 mL) for 16 hours, filtered, washed twice with methanol (99.8 %, 25 mL) and dried in a vacuum oven at 60*C for 16-24 hours under reduced pressure (20 mm) to give 18.6 g of purified product (>97% by HPLC).
WO 2007/061908 PCTIUS2006/044798 110 Example E3: A mixture of crude rebaudioside A (55% purity, 50 g), ethanol (95%, 160 mL), methanol (99.8 %, 60 rnL) and water (25 mL) was combined by stirring at 22*C. The white product crystallized out in 15-30 minutes. The mixture was stirred for an additional 5. 48 hours. The white crystalline product was filtered and washed twice with ethanol (95%, 25 mL). The wet cake of white crystalline product was slurried in methanol (99.8 %, 350 mL) for 16 hours, filtered, washed twice with methanol (99.8 %, 25 mL) and dried in a vacuum oven at 60*C for 16-24 hours under reduced pressure (20 mm) to give 22.2 g of purified product (>97% by HPLC). 10 Example F A solution of rebaudioside A ( >97% pure by HPLC ) was prepared in double distilled water (12.5 gin in 50 mL, 25 % concentration) by stirring the mixture at 40*C for 5 minutes. An amorphous rebaudioside A polymorph was formed by immediately using 15 the clear solution for spray drying with the Lab-Plant spray.drier SD-04 instrument (Lab Plant Ltd., West Yorkshire, U.K.). The solution was fed through the feed pump into the nozzle atomizer which atomized it into a spray of droplets with the help of a constant flow of nitrogen / air. Moisture was evaporated from the droplets under controlled temperature conditions (about 90 to about 97*c) and airflow conditions in the drying chamber and 20 resulted in the formation of dry particles. This dry powder (11-12 g, H 2 0 6.74 %) was discharged continuously from the drying chamber and was collected in a bottle. The solubility in water at room temperature was determined to be > 35.0 % While the invention has been described in detail with respect to specific embodiments thereof, it will be appreciated that those skilled in the art, upon attaining an 25 understanding of the foregoing, may readily conceive of alterations to, variations of, and equivalents to these embodiments. Accordingly, the scope of the present invention should be assessed as that of the appended claims and any equivalents thereof.

Claims (43)

1. A cereal composition comprising: at least one cereal ingredient; 5 at least one high-potency sweetener; and at least one sweet taste improving composition.
2. The cereal composition of claim 1, wherein the at least one high-potency sweetener comprises a natural high-potency sweetener selected from the group consisting of rebaudioside A, rebaudioside B, -rebaudioside C, rebaudioside D, rebaudioside E, 10 dulcoside A, dulcoside B, rubusoside, stevia, stevioside, mogroside IV, mogroside V, Luo Han Guo sweetener, siamenoside, monatin and its salts (monatin SS, RR, RS, SR), curculin, glycyrrhizic acid and its salts, thaumatin, monellin, mabinlin, brazzein, hemandulcin, phyllodulcin, glycyphyllin, phloridzin, trilobatin, baiyunoside, osladin, polypodoside A, pterocaryoside A, pterocaryoside B, mukurozioside, phlomisoside I, 15 periandrin 1, abrusoside A, cyclocarioside I, and combinations thereof.
3. The cereal composition of claim 1, wherein the at least one high-potency sweetener comprises a synthetic high-potency sweetener selected from the group consisting of sucralose, acesulfame potassium and other salts, aspartame, alitame, saccharin, neohesperidin dihydrochalcone, cyclamate, neotame, N-[N-[3-(3-hydroxy-4 20 methoxyphenyl)propyl]-L-ct-aspartyl]-L-phenylalanine 1-methyl ester, N-[N-[3-(3 hydroxy-4-methoxyphenyl)-3-methylbutyl]-L--a-aspartyll-L-phenylalanine 1-methyl ester, N-[N-[3-(3-methoxy-4-hydroxyphenyl)propyl]-L-a-aspartyl]-L-phenylalanine 1-methyl ester, salts thereof, and combinations thereof.
4. The cereal composition of claim 1, wherein the at least one sweet taste 25 improving composition comprises a first sweet taste improving composition selected from the group consisting of carbohydrates, polyols, amino acids and their corresponding salts, polyamino acids and their corresponding salts, sugar acids and their corresponding salts, organic acids, inorganic acids, organic salts, inorganic salts, bitter compounds, flavorants, astringent compounds, polymers, proteins or protein hydrolysates, surfactants, emulsifiers, 30 flavonoids, alcohols, and combinations thereof. WO 2007/061908 PCT/US2006/044798 112
5. The cereal composition of claim 1, wherein the at least one sweet taste improving composition imparts a more sugar-like temporal profile to the cereal composition than the sweetener would have without the at least one sweet taste improving composition 5
6. The cereal composition of claim 1, further comprising at least one second sweet taste improving composition different from the at least one first sweet taste improving composition and selected from the group consisting of carbohydrates, polyols, amino acids and their corresponding salts, polyamino acids and their corresponding salts, sugar acids and their corresponding salts, organic acids, inorganic acids, organic salts, 10 inorganic salts, bitter compounds, flavorants, astringent compounds, polymers, proteins or protein hydrolysates, surfactants, emulsifiers, flavonoids, alcohols, and combinations thereof.
7. The cereal composition of claim 6, further comprising at least one third sweet taste improving composition different from the at least one first sweet taste 15 improving composition and the at least one second sweet taste improving composition and selected from the group consisting of carbohydrates, polyols, amino acids and their corresponding salts, polyamino acids and their corresponding salts, sugar acids and their corresponding salts, organic acids, inorganic acids, organic salts, inorganic salts, bitter compounds, flavorants, astringent compounds, polymers, proteins or protein hydrolysates, 20 surfactants, emulsifiers, flavonoids, alcohols, and combinations thereof.
8. The cereal composition of claim 1, wherein the at least one high-potency sweetener is rebaudioside A, stevioside, stevia, or combinations thereof.
9. The cereal composition of claim 8, wherein the at least one sweet taste improving composition comprises a polyol. 25
10. The cereal composition of claim 9, wherein the at least one polyol comprises erythritol.
11. The cereal composition of claim 9, wherein the at least one polyol comprises xylitol. WO 2007/061908 PCT/US2006/044798 113
12. The cereal composition of claim 8, wherein the at least one sweet taste improving composition comprises at least one amino acid.
13. The cereal composition of claim 12, wherein the at least one amino acid comprises glycine. alanine, proline, hydroxyproline, glutamine, or combinations thereof. 5
14. The cereal composition of claim 8, wherein the at least one sweet taste improving composition comprises at least one polyamino acid.
15. The cereal composition of claim 14, wherein the at least one polyamino acid comprises poly-L-aspartic acid, poly-L-a-lysine, poly-L-c-lysine, poly-L-a-omithine, poly-L-s-ornithine, poly-L-arginine, salts thereof, or combinations thereof. 10
16. The cereal composition of claim 8, wherein the at least one sweet taste improving composition comprises at least one inorganic salt.
17. The cereal composition of claim 16, wherein the at least one inorganic salt comprises a sodium, potassium, calcium, or magnesium salt.
18. The cereal composition of claim 16, further comprising at least one 15 inorganic phosphate.
19. The cereal composition of claim 18, wherein the at least one inorganic phosphate comprises a sodium, potassium, calcium, or magnesium phosphate.
20. The cereal composition of claim 16, further comprising at least one inorganic chloride. 20
21. The cereal composition of claim 20, wherein the at least one inorganic chloride comprises a sodium, potassium, calcium, or magnesium chloride.
22. The cereal composition of claim 8, wherein the at least one sweet taste improving composition comprises at least one carbohydrate.
23. The cereal composition of claim 22, wherein the at least one carbohydrate 25 comprises sucrose, high fructose corn syrup, glucose, or sucrose. WO 2007/061908 PCT/US2006/044798 114
24. The cereal composition of claim 23, wherein the at least one carbohydrate is present in the cereal composition in an amount from about 10,000 ppm to about 80,000 ppm of the composition.
25. . The cereal composition of claim 8, wherein the at least one sweet taste 5 improving composition comprises at least one synthetic high-potency sweetener.
26. The cereal composition of claim 25, wherein the at least one synthetic high potency sweetener comprises sucralose, acesulfame potassium or other salts, aspartame, alitame, saccharin, neohesperidin dihydrochalcone, cyclamate, neotame, N-[N-[3-(3 hydroxy-4-methoxyphenyl)propyl]-L-a-aspartyll-L-phenylalanine 1-methyl ester, N-[N 10 [3-(3-hydroxy-4-methoxyphenyl)-3-methylbutyl]-L-a-aspartyl-L-phenylalanine 1-methyl ester, N-[N-[3-(3-methoxy-4-hydroxyphenyl)propyl)-L-a-aspartyl]-L-phenylalanine 1 methyl ester, salts thereof, and combinations thereof.
27. The cereal composition of claim 25, wherein the at least one synthetic high potency sweetener comprises saccharin or acesulfame potassium or other salts. 15
28. The cereal composition of claim 27, wherein the at least one synthetic sweetener is present in the cereal composition in an amount from about 10 ppm to about 100 ppm of the composition.
29. ,The cereal composition of claim 8, wherein the rebaudioside A comprises rebaudioside A in a purity greater than about 70 % rebaudioside A by weight on a dry 20 basis.
30. The cereal composition of claim 8, wherein the rebaudioside A comprises rebaudioside A in a purity greater than about 80 % rebaudioside A by weight on a dry basis.
31. The cereal composition of claim 8, wherein the rebaudioside A comprises 25 rebaudioside A in a purity greater than about 90 % rebaudioside A by weight on a dry basis. WO 2007/061908 PCT/US2006/044798 115
32. The cereal composition of claim 8, wherein the rebaudioside A comprises rebaudioside A in a purity greater than about 97 % rebaudioside by weight on a dry basis.
33. The cereal composition of claim 8, wherein the rebaudioside A comprises rebaudioside A in a purity greater than about 98 % rebaudioside by weight on a dry basis. 5
34. The cereal composition of claim 8, wherein the rebaudioside A comprises rebaudioside A in a purity greater than about 99 % rebaudioside by weight on a dry basis.
35. The cereal composition of claim 1, wherein the cereal ingredient is selected from the group consisting of a whole or a part grain, a whole or a part seed, a whole or a part grass, and combinations thereof. 10
36. The cereal composition of claim 1, wherein the cereal ingredient is a flour or a bran.
37. The cereal composition of claim 1, wherein the cereal ingredient is selected from the group consisting of a maize, a wheat, a rice, a barley, a bran, a bran endosperm, a bulgur, a soghum, a millet, an oat, a rye, a triticale, a buckwheat, a fonio, a quinoa, a bean, 15 a. soybean, an amaranth, a teff, a spelt. a kaniwa, and combinations thereof.
38. The cereal composition of claim 1, wherein the at least one high-potency sweetener is present in the cereal in an amount in the range of about 0.02 to about 1.5 weight percent of the cereal composition.
39. The cereal composition of claim 1, wherein the sweet taste improving 20 composition is present in the cereal in an amount in the range of about 1 to about 5 weight percent of the cereal composition.
40. The cereal composition of claim 1, comprising a breakfast cereal, a hot cereal, or a snack bar.
41. The cereal composition of claim 40, wherein the breakfast cereal has a 25 shredded form, a flaky form, a puffy, form, or an extruded form. WO 2007/061908 PCT/US2006/044798 116
42. The cereal composition of claim 40, wherein the hot cereal comprises a grit, a porridge, a polenta, a rice, or a rolled oat.
43. The cereal composition of claim 40, wherein the snack bar comprises an energy bar, a rice cake, a granola bar, or a nutritional bar. 5
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US60/739,302 2005-11-23
US60/739,124 2005-11-23
US60/805,216 2006-06-19
US11/555,778 2006-11-02
AU2006318708A AU2006318708B2 (en) 2005-11-23 2006-11-17 Cereal composition comprising high-potency sweetener
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