AU2012343843B2 - Device and methods to diagnose pancreatic cancer - Google Patents

Device and methods to diagnose pancreatic cancer Download PDF

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Publication number
AU2012343843B2
AU2012343843B2 AU2012343843A AU2012343843A AU2012343843B2 AU 2012343843 B2 AU2012343843 B2 AU 2012343843B2 AU 2012343843 A AU2012343843 A AU 2012343843A AU 2012343843 A AU2012343843 A AU 2012343843A AU 2012343843 B2 AU2012343843 B2 AU 2012343843B2
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AU
Australia
Prior art keywords
acid
subject
ceramide
cis
biomarker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2012343843A
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English (en)
Other versions
AU2012343843A1 (en
Inventor
Robert Grutzmann
Holger Kalthoff
Beate Kamlage
Markus M. Lerch
Julia Mayerle
Christian Pilarsky
Regina Reszka
Bodo Schniewind
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Metanomics Health GmbH
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Metanomics Health GmbH
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Filing date
Publication date
Application filed by Metanomics Health GmbH filed Critical Metanomics Health GmbH
Publication of AU2012343843A1 publication Critical patent/AU2012343843A1/en
Application granted granted Critical
Publication of AU2012343843B2 publication Critical patent/AU2012343843B2/en
Priority to AU2018203939A priority Critical patent/AU2018203939A1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Gastroenterology & Hepatology (AREA)
AU2012343843A 2011-11-30 2012-11-29 Device and methods to diagnose pancreatic cancer Ceased AU2012343843B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2018203939A AU2018203939A1 (en) 2011-11-30 2018-06-04 Device and methods to diagnose pancreatic cancer

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161564891P 2011-11-30 2011-11-30
EP11191365.3 2011-11-30
EP11191365 2011-11-30
US61/564,891 2011-11-30
PCT/EP2012/073965 WO2013079594A1 (en) 2011-11-30 2012-11-29 Device and methods to diagnose pancreatic cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018203939A Division AU2018203939A1 (en) 2011-11-30 2018-06-04 Device and methods to diagnose pancreatic cancer

Publications (2)

Publication Number Publication Date
AU2012343843A1 AU2012343843A1 (en) 2014-06-12
AU2012343843B2 true AU2012343843B2 (en) 2018-03-08

Family

ID=48534696

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2012343843A Ceased AU2012343843B2 (en) 2011-11-30 2012-11-29 Device and methods to diagnose pancreatic cancer
AU2018203939A Abandoned AU2018203939A1 (en) 2011-11-30 2018-06-04 Device and methods to diagnose pancreatic cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2018203939A Abandoned AU2018203939A1 (en) 2011-11-30 2018-06-04 Device and methods to diagnose pancreatic cancer

Country Status (6)

Country Link
US (1) US20140323352A1 (https=)
EP (2) EP2786152B1 (https=)
JP (2) JP6219300B2 (https=)
AU (2) AU2012343843B2 (https=)
CA (1) CA2857401A1 (https=)
WO (1) WO2013079594A1 (https=)

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WO2014084290A1 (ja) 2012-11-27 2014-06-05 味の素株式会社 膵臓癌の評価方法、膵臓癌評価装置、膵臓癌評価方法、膵臓癌評価プログラム、膵臓癌評価システムおよび情報通信端末装置
AU2014368412A1 (en) 2013-12-20 2016-07-07 Metanomics Health Gmbh Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel
EP3146334B1 (en) * 2014-05-23 2019-08-14 Institut National de la Sante et de la Recherche Medicale (INSERM) Methods for determining whether a patient will achieve a response after radiation therapy
JP2017525970A (ja) * 2014-09-01 2017-09-07 メタノミクス ゲーエムベーハー 被験体において心不全を診断するための手段及び方法
EP3314264A1 (en) 2015-06-25 2018-05-02 Metanomics Health GmbH Means and methods for diagnosing pancreatic cancer in a subject based on a biomarker panel
US20180238914A1 (en) * 2015-08-19 2018-08-23 Metanomics Gmbh Means and methods for diagnosing cardiac disease in a subject
JPWO2018066620A1 (ja) * 2016-10-04 2019-07-18 味の素株式会社 膵臓癌の評価方法、評価装置、評価プログラム、評価システム、及び端末装置
KR102549063B1 (ko) * 2016-12-15 2023-06-28 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 췌관 선암종의 검출 및 치료를 위한 방법
EP3502699A1 (en) 2017-12-20 2019-06-26 Metanomics Health GmbH Methods for diagnosing pancreatic cancer
EP3806719B1 (en) * 2018-06-14 2025-08-20 Metabolomycs, Inc. Metabolomic signatures for diagnosing and prognosing ovarian cancer
KR102070916B1 (ko) * 2018-08-31 2020-01-29 연세대학교 산학협력단 췌장암 환자의 예후를 예측하기 위한 바이오마커 및 이의 용도
KR102239206B1 (ko) * 2019-03-06 2021-04-12 연세대학교 산학협력단 절제술 효과 평가 장치 및 시스템
ES2799973A1 (es) * 2019-06-19 2020-12-22 Univ Granada Panel de metabolitos como biomarcadores para el diagnostico de cancer de pancreas
WO2022140380A1 (en) * 2020-12-21 2022-06-30 Pancreomics Llc Metabolomic signatures for predicting, diagnosing, and prognosing chronic pancreatitis
CN113655142B (zh) * 2021-08-09 2023-11-10 大连医科大学附属第一医院 一种基于磷脂酰丝氨酸和磷脂酰乙醇胺的早期预警重症急性胰腺炎的模型与应用
CN114371239B (zh) * 2022-03-22 2022-07-15 长沙都正医学检验有限责任公司 用于测定氧化三甲胺的试剂盒及其制备方法和应用
TWI859033B (zh) 2023-12-18 2024-10-11 安益藥業股份有限公司 一種診斷犬科動物胰臟炎的方法與試劑組與一種使用醯基肉鹼作為診斷犬科動物胰臟炎之用途

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EP0368222A1 (en) * 1988-11-09 1990-05-16 Hoechst Japan Limited Anti-fucosylceramide monoclonal antibody
WO2011151252A2 (en) * 2010-06-01 2011-12-08 Metanomics Health Gmbh Means and methods for diagnosing pancreatic cancer in a subject
WO2011163332A2 (en) * 2010-06-23 2011-12-29 University Of Louisville Research Foundation, Inc. Methods for detecting cancer

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US4540884A (en) 1982-12-29 1985-09-10 Finnigan Corporation Method of mass analyzing a sample by use of a quadrupole ion trap
US6083929A (en) * 1991-05-06 2000-07-04 The Biomembrane Institute Extended type 1 chain glycosphingolipids as tumor-associated antigens
US5397894A (en) 1993-05-28 1995-03-14 Varian Associates, Inc. Method of high mass resolution scanning of an ion trap mass spectrometer
JP2005526962A (ja) 2002-02-28 2005-09-08 メタノミクス ゲーエムベーハー ウント ツェーオー．カーゲーアーアー 物質の混合物を分析する質量分析方法
AU2003271173A1 (en) * 2002-10-11 2004-05-04 Chugai Seiyaku Kabushiki Kaisha Cell growth regulator
SG10201405975VA (en) * 2009-10-01 2014-11-27 Phenomenome Discoveries Inc Serum-based biomarkers of pancreatic cancer and uses thereof for diseasedetection and diagnosis
JP2013540995A (ja) * 2010-08-18 2013-11-07 カリス ライフ サイエンシズ ルクセンブルク ホールディングス エス．アー．エール．エル． 疾患に対する循環バイオマーカー
CN105572276B (zh) * 2014-11-07 2018-12-18 上海市第六人民医院 胰腺癌诊断标记物组合、应用及其测定方法

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Publication number Priority date Publication date Assignee Title
EP0368222A1 (en) * 1988-11-09 1990-05-16 Hoechst Japan Limited Anti-fucosylceramide monoclonal antibody
WO2011151252A2 (en) * 2010-06-01 2011-12-08 Metanomics Health Gmbh Means and methods for diagnosing pancreatic cancer in a subject
WO2011163332A2 (en) * 2010-06-23 2011-12-29 University Of Louisville Research Foundation, Inc. Methods for detecting cancer

Non-Patent Citations (1)

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Hinoda Y, Imai K, Itoh F, Nakagawa N, Naiki M, Yachi A. Application of monoclonal antibody KH2 against lactosyl and neolactotetraosyl ceramide to immunohistochemical study of human cancers. Tumour Biol. 1989;10(5):268-74 *

Also Published As

Publication number Publication date
EP2786152B1 (en) 2019-01-02
JP6219300B2 (ja) 2017-10-25
JP2015502541A (ja) 2015-01-22
JP2018049016A (ja) 2018-03-29
EP3486657A2 (en) 2019-05-22
AU2018203939A1 (en) 2018-06-21
WO2013079594A1 (en) 2013-06-06
EP3486657A3 (en) 2019-06-12
AU2012343843A1 (en) 2014-06-12
EP2786152A1 (en) 2014-10-08
US20140323352A1 (en) 2014-10-30
CA2857401A1 (en) 2013-06-06

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired