AU2012310251B2 - Tamper resistant immediate release formulations - Google Patents
Tamper resistant immediate release formulations Download PDFInfo
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- AU2012310251B2 AU2012310251B2 AU2012310251A AU2012310251A AU2012310251B2 AU 2012310251 B2 AU2012310251 B2 AU 2012310251B2 AU 2012310251 A AU2012310251 A AU 2012310251A AU 2012310251 A AU2012310251 A AU 2012310251A AU 2012310251 B2 AU2012310251 B2 AU 2012310251B2
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161535758P | 2011-09-16 | 2011-09-16 | |
| US61/535,758 | 2011-09-16 | ||
| PCT/IB2012/001916 WO2013038268A1 (en) | 2011-09-16 | 2012-09-14 | Tamper resistant immediate release formulations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU2012310251A1 AU2012310251A1 (en) | 2013-05-09 |
| AU2012310251A8 AU2012310251A8 (en) | 2013-06-20 |
| AU2012310251B2 true AU2012310251B2 (en) | 2016-01-21 |
Family
ID=48577967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012310251A Active AU2012310251B2 (en) | 2011-09-16 | 2012-09-14 | Tamper resistant immediate release formulations |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20140294947A1 (https=) |
| EP (2) | EP2755638B1 (https=) |
| JP (1) | JP6138798B2 (https=) |
| AU (1) | AU2012310251B2 (https=) |
| ES (2) | ES2703688T3 (https=) |
| IL (1) | IL231482A (https=) |
| MX (1) | MX347961B (https=) |
| WO (1) | WO2013038268A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040234602A1 (en) | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
| EP1429744A1 (en) | 2001-09-21 | 2004-06-23 | Egalet A/S | Morphine polymer release system |
| WO2004084868A1 (en) | 2003-03-26 | 2004-10-07 | Egalet A/S | Morphine controlled release system |
| US8821928B2 (en) | 2007-06-04 | 2014-09-02 | Egalet Ltd. | Controlled release pharmaceutical compositions for prolonged effect |
| CA2751667C (en) | 2009-02-06 | 2016-12-13 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
| NZ597283A (en) | 2009-06-24 | 2013-07-26 | Egalet Ltd | Controlled release formulations |
| AU2013285988A1 (en) | 2012-07-06 | 2015-02-12 | Egalet Ltd. | Abuse deterrent pharmaceutical compositions for controlled release |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| CA2955229C (en) | 2014-07-17 | 2020-03-10 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| US9132096B1 (en) | 2014-09-12 | 2015-09-15 | Alkermes Pharma Ireland Limited | Abuse resistant pharmaceutical compositions |
| WO2016064873A1 (en) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| WO2019070581A1 (en) * | 2017-10-02 | 2019-04-11 | Purdue Pharma L.P | PHARMACEUTICAL COMPOSITIONS COMPRISING GELIFYING AGENT COMPOSITIONS |
| AU2018390826B2 (en) | 2017-12-20 | 2024-09-12 | Purdue Pharma L.P. | Abuse deterrent morphine sulfate dosage forms |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070224129A1 (en) * | 2005-11-10 | 2007-09-27 | Flamel Technologies, Inc. | Anti-misuse microparticulate oral pharmaceutical form |
| EP1897545A1 (en) * | 2006-08-25 | 2008-03-12 | Purdue Pharma LP | Tamper resistant oral pharmaceutical dosage forms comprising an opioid analgesic |
| US20080063725A1 (en) * | 2006-05-24 | 2008-03-13 | Flamel Technologies | Prolonged-release multimicroparticulate oral pharmaceutical form |
| WO2009023672A2 (en) * | 2007-08-13 | 2009-02-19 | Abuse Deterrent Pharmaceutical Llc | Abuse resistant drugs, method of use and method of making |
| WO2009025859A1 (en) * | 2007-08-21 | 2009-02-26 | Teva Pharmaceutical Industries Ltd. | Paliperidone sustained release formulation |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9401894D0 (en) * | 1994-02-01 | 1994-03-30 | Rhone Poulenc Rorer Ltd | New compositions of matter |
| US5654005A (en) * | 1995-06-07 | 1997-08-05 | Andrx Pharmaceuticals, Inc. | Controlled release formulation having a preformed passageway |
| AU2003271024A1 (en) * | 2002-09-21 | 2004-04-08 | Jin Wang | Sustained release compound of acetamidophenol and tramadol |
| NZ547284A (en) * | 2003-10-31 | 2009-12-24 | Hexal Ag | Pharmaceutical agent-containing formulation comprising a coating of a film forming polymer |
| ES2281851T3 (es) * | 2003-12-09 | 2007-10-01 | Euro-Celtique S.A. | Forma de dosis co-extruida resistente a la manipulacion conteniendo un agente activo y un agente adverso y proceso para preparar el mismo. |
| TWI365880B (en) | 2004-03-30 | 2012-06-11 | Euro Celtique Sa | Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and oxycodone hydrochloride composition,pharmaceutical dosage form,sustained release oeal dosage form and pharmaceutically acceptable package having less than 25 pp |
| US20080152595A1 (en) * | 2004-11-24 | 2008-06-26 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
| SI2719378T1 (sl) * | 2006-06-19 | 2016-11-30 | Alpharma Pharmaceuticals Llc | Farmacevtski sestavki |
| MX2010013169A (es) * | 2008-06-02 | 2010-12-21 | Reddy S Lab Ltd | Formulaciones de niacina de liberacion modificada. |
| PH12013501345A1 (en) * | 2010-12-23 | 2022-10-24 | Purdue Pharma Lp | Tamper resistant solid oral dosage forms |
| AU2012289764B2 (en) * | 2011-07-29 | 2017-03-02 | Grünenthal GmbH | Tamper-resistant tablet providing immediate drug release |
-
2012
- 2012-09-14 EP EP12772421.9A patent/EP2755638B1/en active Active
- 2012-09-14 JP JP2014530332A patent/JP6138798B2/ja active Active
- 2012-09-14 WO PCT/IB2012/001916 patent/WO2013038268A1/en not_active Ceased
- 2012-09-14 ES ES16167881T patent/ES2703688T3/es active Active
- 2012-09-14 AU AU2012310251A patent/AU2012310251B2/en active Active
- 2012-09-14 EP EP16167881.8A patent/EP3078370B1/en active Active
- 2012-09-14 US US14/344,271 patent/US20140294947A1/en not_active Abandoned
- 2012-09-14 MX MX2014003192A patent/MX347961B/es active IP Right Grant
- 2012-09-14 ES ES12772421.9T patent/ES2583132T3/es active Active
-
2014
- 2014-03-12 IL IL231482A patent/IL231482A/en active IP Right Grant
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070224129A1 (en) * | 2005-11-10 | 2007-09-27 | Flamel Technologies, Inc. | Anti-misuse microparticulate oral pharmaceutical form |
| US20080063725A1 (en) * | 2006-05-24 | 2008-03-13 | Flamel Technologies | Prolonged-release multimicroparticulate oral pharmaceutical form |
| EP1897545A1 (en) * | 2006-08-25 | 2008-03-12 | Purdue Pharma LP | Tamper resistant oral pharmaceutical dosage forms comprising an opioid analgesic |
| WO2009023672A2 (en) * | 2007-08-13 | 2009-02-19 | Abuse Deterrent Pharmaceutical Llc | Abuse resistant drugs, method of use and method of making |
| WO2009025859A1 (en) * | 2007-08-21 | 2009-02-26 | Teva Pharmaceutical Industries Ltd. | Paliperidone sustained release formulation |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2703688T3 (es) | 2019-03-12 |
| JP2014530185A (ja) | 2014-11-17 |
| AU2012310251A1 (en) | 2013-05-09 |
| EP3078370B1 (en) | 2018-11-07 |
| EP2755638B1 (en) | 2016-06-01 |
| AU2012310251A8 (en) | 2013-06-20 |
| WO2013038268A1 (en) | 2013-03-21 |
| EP3078370A1 (en) | 2016-10-12 |
| ES2583132T3 (es) | 2016-09-19 |
| MX347961B (es) | 2017-05-19 |
| JP6138798B2 (ja) | 2017-05-31 |
| WO2013038268A8 (en) | 2013-06-13 |
| EP2755638A1 (en) | 2014-07-23 |
| IL231482A0 (en) | 2014-04-30 |
| US20140294947A1 (en) | 2014-10-02 |
| IL231482A (en) | 2017-03-30 |
| MX2014003192A (es) | 2015-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TH | Corrigenda |
Free format text: IN VOL 27 , NO 17 , PAGE(S) 2736 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE - NAME INDEX UNDER THE NAME PURDUE PHARMA L.P., APPLICATION NO. 2012310251, UNDER INID (31) CORRECT THE NUMBER TO 61/535,758 |
|
| FGA | Letters patent sealed or granted (standard patent) |