AU2012229983A1 - Substituted imadazapyrinidin-5(6H)-ones as allosteric modulators of mGluR5 receptors - Google Patents
Substituted imadazapyrinidin-5(6H)-ones as allosteric modulators of mGluR5 receptors Download PDFInfo
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Classifications
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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Landscapes
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- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161452921P | 2011-03-15 | 2011-03-15 | |
| US61/452,921 | 2011-03-15 | ||
| PCT/US2012/029085 WO2012125732A1 (en) | 2011-03-15 | 2012-03-14 | Substituted imadazapyrinidin-5(6h)-ones as allosteric modulators of mglur5 receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2012229983A1 true AU2012229983A1 (en) | 2013-10-03 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012229983A Abandoned AU2012229983A1 (en) | 2011-03-15 | 2012-03-14 | Substituted imadazapyrinidin-5(6H)-ones as allosteric modulators of mGluR5 receptors |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP2685825A4 (ja) |
| JP (1) | JP2014508172A (ja) |
| AU (1) | AU2012229983A1 (ja) |
| CA (1) | CA2830220A1 (ja) |
| WO (1) | WO2012125732A1 (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9255103B2 (en) | 2010-12-08 | 2016-02-09 | Vanderbilt University | Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulators |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8865725B2 (en) * | 2011-03-15 | 2014-10-21 | Vanderbilt University | Substituted imidazopyrimidin-5(6H)-ones as allosteric modulators of MGLUR5 receptors |
| US9682980B2 (en) * | 2012-06-21 | 2017-06-20 | Bristol-Myers Squibb Company | Positive allosteric modulators of mGluR2 |
| TWI713497B (zh) * | 2015-02-26 | 2020-12-21 | 南韓商愛思開生物製藥股份有限公司 | 咪唑并嘧啶及咪唑并三衍生物及包含該衍生物之醫藥組成物 |
| CN114929230A (zh) * | 2019-10-21 | 2022-08-19 | 爱思开生物制药株式会社 | 咪唑并嘧啶或咪唑并三嗪化合物用于预防、减轻或治疗认知障碍或者用于改善认知功能的用途 |
| WO2023064223A1 (en) | 2021-10-11 | 2023-04-20 | Gossamer Bio Services, Inc. | Tri-substituted pyridines |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8334210D0 (en) * | 1983-12-22 | 1984-02-01 | Roussel Lab Ltd | Imidazo(1 2-c)pyrimidines |
| JPH01203366A (ja) * | 1988-02-10 | 1989-08-16 | Mitsui Petrochem Ind Ltd | Ｎ−置換イミダゾール誘導体 |
| WO2007034282A2 (en) * | 2005-09-19 | 2007-03-29 | Pfizer Products Inc. | Diaryl-imidazole compounds condensed with a heterocycle as c3a receptor antagonists |
| US7985753B2 (en) * | 2006-08-04 | 2011-07-26 | Merz Pharma Gmbh & Co. Kgaa | Substituted pyrazolo[1,5-A]pyrimidines as metabotropic glutamate receptor modulators |
| US20080146523A1 (en) * | 2006-12-18 | 2008-06-19 | Guido Galley | Imidazole derivatives |
| GB0704230D0 (en) * | 2007-03-05 | 2007-04-11 | Novartis Ag | Organic compounds |
| US8034806B2 (en) * | 2007-11-02 | 2011-10-11 | Vanderbilt University | Bicyclic mGluR5 positive allosteric modulators and methods of making and using same |
| EP2651222A4 (en) * | 2010-12-17 | 2014-04-30 | Univ Vanderbilt | BICYCLIC TRIAZOL AND PYRAZOLLACTAME AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS |
-
2012
- 2012-03-14 EP EP12757940.7A patent/EP2685825A4/en not_active Withdrawn
- 2012-03-14 WO PCT/US2012/029085 patent/WO2012125732A1/en active Application Filing
- 2012-03-14 JP JP2013558139A patent/JP2014508172A/ja active Pending
- 2012-03-14 CA CA2830220A patent/CA2830220A1/en not_active Abandoned
- 2012-03-14 AU AU2012229983A patent/AU2012229983A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9255103B2 (en) | 2010-12-08 | 2016-02-09 | Vanderbilt University | Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulators |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012125732A8 (en) | 2013-10-17 |
| EP2685825A4 (en) | 2014-09-10 |
| EP2685825A1 (en) | 2014-01-22 |
| CA2830220A1 (en) | 2012-09-20 |
| JP2014508172A (ja) | 2014-04-03 |
| WO2012125732A1 (en) | 2012-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |