AU2010306559B2 - Recombinant modified vaccinia Ankara (MVA) vaccinia virus containing restructured insertion sites - Google Patents

Recombinant modified vaccinia Ankara (MVA) vaccinia virus containing restructured insertion sites Download PDF

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AU2010306559B2
AU2010306559B2 AU2010306559A AU2010306559A AU2010306559B2 AU 2010306559 B2 AU2010306559 B2 AU 2010306559B2 AU 2010306559 A AU2010306559 A AU 2010306559A AU 2010306559 A AU2010306559 A AU 2010306559A AU 2010306559 B2 AU2010306559 B2 AU 2010306559B2
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nucleic acid
mva
virus
essential
recombinant
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AU2010306559A1 (en
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Patricia L. Earl
Bernard Moss
Linda S. Wyatt
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United States Department of Health and Human Services
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
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    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24151—Methods of production or purification of viral material
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    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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AU2010306559A 2009-10-16 2010-10-15 Recombinant modified vaccinia Ankara (MVA) vaccinia virus containing restructured insertion sites Active AU2010306559B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25232609P 2009-10-16 2009-10-16
US61/252,326 2009-10-16
PCT/US2010/052929 WO2011047324A1 (en) 2009-10-16 2010-10-15 Recombinant modified vaccinia ankara (mva) vaccinia virus containing restructured insertion sites

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AU2010306559A1 AU2010306559A1 (en) 2012-06-07
AU2010306559B2 true AU2010306559B2 (en) 2015-07-16

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US (2) US9133480B2 (enExample)
EP (1) EP2488649B1 (enExample)
JP (1) JP5789263B2 (enExample)
AU (1) AU2010306559B2 (enExample)
CA (1) CA2777744C (enExample)
DK (1) DK2488649T3 (enExample)
WO (1) WO2011047324A1 (enExample)
ZA (1) ZA201203551B (enExample)

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DK2402451T3 (en) * 2006-08-25 2018-06-25 The Government Of The Us Secretary Department Of Health And Human Services Method for Stabilizing a DNA Insert in a Recombinant Vaccine Vector
US8580276B2 (en) 2009-06-05 2013-11-12 City Of Hope Genetically stable recombinant modified vaccinia ankara (rMVA) vaccines and methods of preparation thereof
WO2011047324A1 (en) 2009-10-16 2011-04-21 The U.S.A. As Represented By The Secretary , Department Of Health And Human Services . Recombinant modified vaccinia ankara (mva) vaccinia virus containing restructured insertion sites
EP2620446A1 (en) 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
DK3198017T3 (da) 2014-09-26 2021-04-12 Us Health Virusbaserede ekspressionsvektorer og anvendelser deraf
US11701418B2 (en) 2015-01-12 2023-07-18 Geovax, Inc. Replication-deficient modified vaccinia Ankara (MVA) expressing Ebola virus glycoprotein (GP) and matrix protein (VP40)
EP3355924A1 (en) 2015-09-29 2018-08-08 The U.S.A. as represented by the Secretary, Department of Health and Human Services Methods of treating and preventing amyotrophic lateral sclerosis
CN109071592B (zh) * 2016-01-08 2022-07-19 吉奥瓦科斯公司 用于产生对肿瘤相关抗原的免疫应答的组合物和方法
US20190030157A1 (en) 2016-02-03 2019-01-31 Geovax Inc. Compositions and Methods for Generating an Immune Response to a Flavivirus
US11052148B2 (en) 2016-05-30 2021-07-06 Geo Vax, Inc. Compositions and methods for generating an immune response to hepatitis B virus
US11311612B2 (en) 2017-09-19 2022-04-26 Geovax, Inc. Compositions and methods for generating an immune response to treat or prevent malaria
US11590219B2 (en) 2018-01-30 2023-02-28 Emory University Compositions and methods for promoting immune responses to human immunodeficiency virus
WO2019217922A1 (en) 2018-05-11 2019-11-14 City Of Hope Genetically modified recombinant vaccinia ankara (rmva) vaccines of improved stability and methods of preparation thereof
CN113924114A (zh) 2019-05-22 2022-01-11 吉利德科学公司 Tlr7调节化合物和hiv疫苗的组合
EP4043482A4 (en) * 2019-10-02 2024-03-13 Bionoxx Inc. TUMOR TARGETING PROTEIN OR ASSOCIATED FRAGMENT, ANTIBODIES BINDING THEREWITH AND ITS USE
AU2020384323A1 (en) 2019-11-14 2022-06-02 Aelix Therapeutics, S.L. Dosage regimens for vaccines
CA3167052A1 (en) 2020-02-14 2021-08-19 Mary Jo Hauser Vaccines and uses thereof to induce an immune response to sars-cov2
EP4153228A4 (en) 2020-05-17 2024-07-10 City of Hope CORONAVIRUS VACCINES BASED ON SYNTHETIC MODIFIED ANKARA VACCINE (SMVA) VIRUS
BR112023015467A2 (pt) 2021-02-02 2023-10-10 Geovax Inc Vetor viral de vaccinia ankara recombinante modificado, métodos para aumentar uma resposta imunológica a um antígeno alvo em um paciente e para prevenir, tratar ou induzir uma resposta imunológica contra um antígeno alvo, e, composição farmacêutica

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WO2011047324A1 (en) 2009-10-16 2011-04-21 The U.S.A. As Represented By The Secretary , Department Of Health And Human Services . Recombinant modified vaccinia ankara (mva) vaccinia virus containing restructured insertion sites

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Publication number Publication date
US20160040135A1 (en) 2016-02-11
JP5789263B2 (ja) 2015-10-07
CA2777744A1 (en) 2011-04-21
US9879231B2 (en) 2018-01-30
EP2488649B1 (en) 2019-04-03
EP2488649A1 (en) 2012-08-22
US20120263750A1 (en) 2012-10-18
WO2011047324A1 (en) 2011-04-21
AU2010306559A1 (en) 2012-06-07
US9133480B2 (en) 2015-09-15
DK2488649T3 (da) 2019-06-17
ZA201203551B (en) 2013-01-30
CA2777744C (en) 2019-09-24
JP2013507935A (ja) 2013-03-07

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