AU2009246134B2 - Genetic alterations on chromosomes 21q, 6q and 15q and methods of use thereof for the diagnosis and treatment of type I diabetes - Google Patents
Genetic alterations on chromosomes 21q, 6q and 15q and methods of use thereof for the diagnosis and treatment of type I diabetes Download PDFInfo
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| US61/054,040 | 2008-05-16 | ||
| PCT/US2009/044356 WO2009140679A2 (en) | 2008-05-16 | 2009-05-18 | Genetic alterations on chromosomes 21q, 6q and 15q and methods of use thereof for the diagnosis and treatment of type i diabetes |
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| JP5899527B2 (ja) * | 2011-03-14 | 2016-04-06 | 国立研究開発法人理化学研究所 | 第６染色体短腕２１．３３領域の一塩基多型に基づく抗てんかん薬による薬疹リスクの検査方法 |
| US10125395B2 (en) * | 2011-10-18 | 2018-11-13 | The Children's Hospital Of Philadelphia | Genetic alterations and methods of use thereof for the diagnosis and treatment of type I diabetes |
| CN109402117B (zh) * | 2018-11-07 | 2022-03-01 | 上海中医药大学附属曙光医院 | 一种沉默小鼠肠道rasgrp1表达的腺相关病毒及其制备方法和应用 |
| KR102169699B1 (ko) * | 2019-12-27 | 2020-10-23 | 주식회사 클리노믹스 | 유전자 검사를 위한 맞춤형 유전자칩 및 이의 제작 방법 |
| CN114427002B (zh) * | 2022-03-17 | 2023-06-02 | 江苏省人民医院（南京医科大学第一附属医院） | 基于22个snp易感位点评估1型糖尿病患病风险的试剂盒 |
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| US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| CA2127450C (en) | 1992-01-07 | 2007-04-17 | Samuel Wadsworth | Transgenic animal models for alzheimer's disease |
| US5604102A (en) | 1992-04-15 | 1997-02-18 | Athena Neurosciences, Inc. | Methods of screening for β-amyloid peptide production inhibitors |
| GB9212416D0 (en) | 1992-06-11 | 1992-07-22 | Medical Res Council | Reversible binding substances |
| CA2140343A1 (en) | 1992-07-17 | 1994-02-03 | Sean M. Sullivan | Method and reagent for treatment of animal diseases |
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| US5849999A (en) | 1996-10-16 | 1998-12-15 | The Mclean Hospital Corporation | Transgenic non-human mice expressing Flag-APP-C100 protein develop alzheimer's disease brain morphology and behavior |
| US7312196B2 (en) * | 1997-01-08 | 2007-12-25 | Amylin Pharmaceuticals, Inc. | Formulations for amylin agonist peptides |
| US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
| US6395713B1 (en) | 1997-07-23 | 2002-05-28 | Ribozyme Pharmaceuticals, Inc. | Compositions for the delivery of negatively charged molecules |
| ATE408699T1 (de) | 1999-03-10 | 2008-10-15 | Phogen Ltd | Verabreichung von nukleinsäuren und proteinen an zellen |
| US6841535B2 (en) | 2000-07-31 | 2005-01-11 | Active Motif | Peptide-mediated transfection agents and methods of use |
| US20020130430A1 (en) | 2000-12-29 | 2002-09-19 | Castor Trevor Percival | Methods for making polymer microspheres/nanospheres and encapsulating therapeutic proteins and other products |
| GB0104440D0 (en) * | 2001-02-22 | 2001-04-11 | Oxford Biomedica Ltd | Novel genes |
| US7205106B1 (en) * | 2001-07-20 | 2007-04-17 | Roche Molecular Systems, Inc. | Association of polymorphisms in IL4-related genes with autoimmune disease |
| US20030152951A1 (en) * | 2001-07-20 | 2003-08-14 | Mirel Daniel B. | IL-4 receptor sequence variation associated with type 1 diabetes |
| US7060498B1 (en) | 2001-11-28 | 2006-06-13 | Genta Salus Llc | Polycationic water soluble copolymer and method for transferring polyanionic macromolecules across biological barriers |
| US7141540B2 (en) | 2001-11-30 | 2006-11-28 | Genta Salus Llc | Cyclodextrin grafted biocompatible amphilphilic polymer and methods of preparation and use thereof |
| CA2441701C (en) * | 2002-10-04 | 2010-07-13 | F. Hoffmann-La Roche Ag | Detection of il4 and il13 polymorphisms in determination of type 1 diabetes susceptibility |
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| US7901885B2 (en) * | 2006-05-09 | 2011-03-08 | Dsm Ip Assets B.V. | Genes and markers in type 2 diabetes and obesity |
| WO2007138691A1 (ja) * | 2006-05-31 | 2007-12-06 | National University Corporation Nagoya University | 多発性嚢胞腎疾患関連遺伝子及びその利用 |
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Patent Citations (1)
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| AU2005248147A1 (en) * | 2004-05-11 | 2005-12-08 | Alphagen Co., Ltd. | Polynucleotides for causing RNA interference and method for inhibiting gene expression using the same |
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| NCBI GEO Accession No. GPL6433, "Illumina HumanHap550 Genotyping Beadchip v1", 05 February 2008 * |
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| WO2009140679A9 (en) | 2012-01-05 |
| CA2724475C (en) | 2019-05-07 |
| US10066266B2 (en) | 2018-09-04 |
| JP2011523552A (ja) | 2011-08-18 |
| CA2724475A1 (en) | 2009-11-19 |
| EP2291544B1 (en) | 2017-10-25 |
| AU2009246134A1 (en) | 2009-11-19 |
| WO2009140679A3 (en) | 2010-01-07 |
| US20110236370A1 (en) | 2011-09-29 |
| EP2291544A4 (en) | 2012-09-12 |
| JP6095889B2 (ja) | 2017-03-15 |
| US20150299793A1 (en) | 2015-10-22 |
| WO2009140679A2 (en) | 2009-11-19 |
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| DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ GENETIC ALTERATIONS ON CHROMOSOMES 21Q, 6Q AND 15Q AND METHODS OF USE THEREOF FOR THE DIAGNOSIS AND TREATMENT OF TYPE I DIABETES |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |